Effects of carbon dioxide in the middle ear cavity upon the cochlear potentials and cochlear pH.

Abstract:

:To elucidate the effects of CO2 in the middle ear upon the cochlea, measurements were made of the cochlear potentials (compound action potential and endocochlear potential) and of the pH of the inner ear fluids and the organ of Corti. Gas containing CO2 did not affect the AP threshold, except for a slight decrease in AP threshold elicited by an 8 kHz tone burst with 10% CO2 flow. The EP did not vary with CO2 gas. The CO2 gas mixture reduced the pH in perilymph significantly, by 0.11 +/- 0.05 with 5% CO2 and by 0.17 +/- 0.04 with 10% CO2, in comparison with 100% N2. The CO2 gas slightly but significantly decreased the endolymph pH, by 0.05 +/- 0.04 with 5% CO2 and by 0.09 +/- 0.06 with 10% CO2. The removal of perilymph led to a greater acidification of endolymph with CO2 gas. Acidification of the organ of Corti was also noted with the CO2 gas flush. These findings indicate that CO2 in the middle ear influences the acid-base regulation of inner ear fluids and the cochlear function.

journal_name

Acta Otolaryngol

journal_title

Acta oto-laryngologica

authors

Ikeda K,Morizono T

doi

10.3109/00016488909107397

subject

Has Abstract

pub_date

1989-07-01 00:00:00

pages

88-93

issue

1-2

eissn

0001-6489

issn

1651-2251

journal_volume

108

pub_type

杂志文章
  • Reconstruction of the segmental mandibular defect using a retroauricular or modified face-lift incision with an intraoral approach in head and neck cancer.

    abstract:CONCLUSIONS:This is the first report of mandibular reconstruction using the retroauricular (RA) or the modified face-lift (MFL) approach in head and neck cancer. This approach may have advantages over the conventional approach, especially in its superior aesthetic results. OBJECTIVE:The fibular osseous or osteocutaneo...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.3109/00016489.2014.986757

    authors: Kim WS,Jittreetat T,Nam W,Sannikorn P,Choi EC,Koh YW

    更新日期:2015-05-01 00:00:00

  • Allergen-induced specific and non-specific nasal reactions. Reciprocal relationship and inhibition by topical glucocorticosteroids.

    abstract::The correlation between allergen-induced specific and non-specific (histamine) nasal reactions was studied, especially as regards topical glucocorticosteroid effects on the non-specific reactions. Thirteen patients with strictly seasonal allergic rhinitis participated. A nasal challenge with histamine and three increa...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.3109/00016488909127508

    authors: Andersson M,Andersson P,Pipkorn U

    更新日期:1989-03-01 00:00:00

  • A comparison of vocal fold closure in rigid telescopic and flexible fiberoptic laryngostroboscopy.

    abstract::Fifteen normal speakers (7 women and 8 men), ranging in age from 21 to 35 years, were examined consecutively with rigid telescopy and flexible fiberscopy during sustained phonation at 3 loudness levels. The endoscopes were connected to a stroboscope and video equipment. The purpose was to investigate whether the two l...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.3109/00016489209100796

    authors: Södersten M,Lindestad PA

    更新日期:1992-01-01 00:00:00

  • Penetration of erythromycin stearate into maxillary sinus mucosa and secretion in chronic maxillary sinusitis.

    abstract::The penetration of oral erythromycin stearate (Abboticin), administered in a dosage of 500 mg three times a day, into the maxillary sinus mucosa and secretion was studied in 15 patients (22 sinuses) operated on for chronic maxillary sinusitis. The average concentration in serum was 2.3 microgram/ml, 1.2 microgram/ml i...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.3109/00016487709123970

    authors: Paavolainen M,Kohonen A,Palva T,Renkonen OV

    更新日期:1977-09-01 00:00:00

  • Studies on the anatomy of the facial nerve.

    abstract::The present study on the anatomy of the human facial nerve is based on the results of a series of gross dissections, and histological and electro-diagnostic examinations. From our findings it follows that there is a definite spatial orientation of the peripheral branches in the facial nerve trunk. The results of the m...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.3109/00016487609119946

    authors: Podvinec M,Pfaltz CR

    更新日期:1976-03-01 00:00:00

  • Intravenous administration of human mesenchymal stem cells after noise- or drug-induced hearing loss in rats.

    abstract:CONCLUSION:Systemic application of human mesenchymal stem cells (hMSCs) may be another effective tool for stem cell supply to the inner ear. OBJECTIVES:Most researchers have used local application to provide the inner ear with stem cells. In spite of their efficacy, these methods can potentially cause irreversible dam...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.3109/00016489.2012.660731

    authors: Choi BY,Song JJ,Chang SO,Kim SU,Oh SH

    更新日期:2012-06-01 00:00:00

  • Morphometric analysis using automated image analysis of CD34-positive vessels in salivary gland acinic cell carcinoma.

    abstract:CONCLUSIONS:In computer-assisted analysis of acinic cell cancer (ACC) morphological characteristics of CD34 immunoreactivity were detected. Bigger vessel size, vessel irregularity, and lower intensity of CD34-positive vessel staining may indicate unfavorable prognosis. OBJECTIVES:Salivary gland cancer (SGC) is a morph...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.1080/00016480601053099

    authors: Luukkaa H,Laitakari J,Vahlberg T,Klemi P,Grénman R

    更新日期:2007-08-01 00:00:00

  • Expression of glycoconjugates in normal and Sjögren's syndrome labial glands.

    abstract::Glyconjugate expression in formalin-fixed, paraffin-embedded Sjögren's syndrome labial glands (nine cases) was compared with that in normal glands (12 samples) using a wide panel of lectins. Mucous cells expressed mainly mucous-type glycoproteins including sialyl, fucosyl, galactosyl and galactosaminosyl residues, and...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.3109/00016489709114217

    authors: Sidagis J,Ueno K,Wang ZH,Hanamure Y,Furuta S,Ohyama M

    更新日期:1997-11-01 00:00:00

  • Meniere's disease and middle ear pressure: vestibular function after transtympanic tube placement.

    abstract:CONCLUSION:Selected patients with Meniere's disease (MD) show an improvement of disability from vertigo after transtympanic ventilation tube insertion, although an effect on vestibular function is not seen if ipsilateral middle ear pressure lower than -50 daPa is used as a selection criterion. OBJECTIVES:Transtympanic...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.3109/00016480902791678

    authors: Park JJ,Chen YS,Westhofen M

    更新日期:2009-12-01 00:00:00

  • Simultaneous and non-simultaneous dual electrode stimulation in cochlear implants: evidence for two neural response modalities.

    abstract:CONCLUSION:There are two modalities of dual electrode stimulation: a shifting, continuous excitation, which is the desired effect, and a split excitation with considerable variation in loudness. The first one most likely occurs in the basal turn, with adjacent contacts, stimulated simultaneously rather than sequentiall...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.1080/00016480802610218

    authors: Frijns JH,Kalkman RK,Vanpoucke FJ,Bongers JS,Briaire JJ

    更新日期:2009-04-01 00:00:00

  • Inner ear injury caused by air intrusion to the scala vestibuli of the cochlea.

    abstract::In a previous communication, we demonstrated that the introduction of air into the scala tympani of the cochlea causes a decrease of cochlear potentials; however, the change in endocochlear dc potential (EP) was mild and the decreased cochlear microphonics (CM) and compound action potentials (CAP) were, at least parti...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.3109/00016489309135892

    authors: Kobayashi T,Sakurada T,Ohyama K,Takasaka M

    更新日期:1993-11-01 00:00:00

  • Outcomes of surgically treated rhinogenic optic neuropathy.

    abstract:CONCLUSION:The visual outcomes of endoscopic treatment of optic neuropathy are favorable. However, no specific prognostic factor was associated with good outcome. OBJECTIVE:To investigate visual outcomes of patients with optic neuropathy caused by paranasal mucocele or sinusitis. METHODS:The clinical course in 38 pat...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.3109/00016489.2011.557837

    authors: Nakaya K,Oshima T,Kudo T,Ikeda R,Hidaka H,Kobayashi T

    更新日期:2011-08-01 00:00:00

  • Tensor tympani, a 'tuner' of tensor palati muscle.

    abstract::The author has proved experimentally (in two dogs) that there is reflex hypertonia of the tensor palati muscle, synchronous with the 'shortening' reaction of the tensor tympani muscle in response to its "static" relaxation during the gradual passive inward displacement of the drum resulting from the negative intratymp...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.3109/00016487609120926

    authors: Misurya VK

    更新日期:1976-11-01 00:00:00

  • Auditory evoked potentials in cats with neonatal high frequency hearing loss. Evidence of abnormal frequency representation in the midbrain.

    abstract::We have recorded auditory evoked potentials, of both neurogenic and myogenic origin, in cats having neonatal high frequency cochlear hearing loss. Using frequency specific stimuli (tone pips) and by measuring responses near to threshold, we have probed tonotopic (or cochleotopic) representation within the brainstem-mi...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.3109/00016489309135763

    authors: Harrison RV,Gordon DC,Nagasawa A,Stanton S,Ibrahim D,Mount RJ

    更新日期:1993-01-01 00:00:00

  • Familial early-onset progressive vestibulopathy without hearing impairment.

    abstract::A family with early-onset vestibulopathy is presented. The 34-year-old father had experienced brief attacks of vertigo and currently suffers from unsteadiness and oscillopsia during head movements. His two young sons also experience brief attacks of spontaneous vertigo. In vestibular testing all three subjects showed ...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.1080/00016480310002500

    authors: Brantberg K

    更新日期:2003-08-01 00:00:00

  • Early timing of low-dose dexamethasone decreases inflammation in a murine model of eosinophilic airway disease.

    abstract:CONCLUSION:A very low dose of dexamethasone (DEX) was as equally as sufficient as a pharmacological dose to decrease eosinophil inflammation in airways and bone marrow. The timing of DEX treatment in relation to allergen challenge was strongly decisive for the outcome of the inflammatory response. OBJECTIVES:We aimed ...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.1080/00016480802126561

    authors: Georén SK,Tcacencu I,Wikström AC,Stierna P

    更新日期:2009-02-01 00:00:00

  • Extracellular ATP-induced Ca2+ mobilization of type I spiral ganglion cells from the guinea pig cochlea.

    abstract::Intracellular calcium concentrations ([Ca2+]i) in type I cochlear spiral ganglion cells (SGCs) of the guinea pig were measured by digital imaging microscopy and the Ca(2+)-sensitive dye Fura-2. Extracellular ATP induced elevation of [Ca2+]i in type I SGCs in a concentration-dependent manner. The ATP-induced elevation ...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.3109/00016489709113435

    authors: Cho H,Harada N,Yamashita T

    更新日期:1997-07-01 00:00:00

  • The roles of local inhibition mediated by gamma-aminobutyric acid (GABA)-A receptor in duration tuning in the inferior colliculus of guinea pigs.

    abstract:CONCLUSION:GABA-mediated inhibition is responsible for the duration tuning in the inferior colliculus (IC) of guinea pigs, a non-echo-locating mammal. Duration tuning in this species is better demonstrated in an appropriate short time window. OBJECTIVES:To investigate the role of GABA-mediated inhibition in duration t...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.1080/00016480701840122

    authors: Yin S,Chen Z,Feng Y,Wang J

    更新日期:2008-10-01 00:00:00

  • Surgery vs. natural course of chronic otitis media. Long-term hearing evaluation.

    abstract::The present paper investigates the hearing function in chronic otitis media vs. tympanoplasty in 41 patients with bilateral chronic otitis media, operated on unilaterally. The auditory evaluation was performed immediately before surgery and at a follow-up time varying from 1 to 14 years (mean = 5 years). Results were ...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.3109/00016489109138410

    authors: Colletti V,Fiorino FG,Indelicato T

    更新日期:1991-01-01 00:00:00

  • Acoustic cues underlying auditory distance in barn owls.

    abstract:CONCLUSIONS:We conclude that: (1) among several cues examined, the monaural cue of direct-to-reverberant (D/R) ratio in the ipsilateral ear provides the most information about sound-source distance; (2) interaural level difference (ILD) provides less information about sound-source distance; and (3) a comprehensive theo...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.1080/00016480701840114

    authors: Kim DO,Moiseff A,Turner JB,Gull J

    更新日期:2008-04-01 00:00:00

  • The relationship between vasomotor symptoms and menopause-associated dizziness.

    abstract:CONCLUSION:Vasomotor symptoms (VMS) and especially hot flushes are negatively associated with recovery from menopause-related dizziness. A further study is justified to determine whether hormone replacement therapy (HRT) can shorten this recovery time. OBJECTIVES:This study aimed to compare the rate of recovery from d...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.3109/00016489.2013.841991

    authors: Owada S,Suzuki M

    更新日期:2014-02-01 00:00:00

  • Objective and subjective evaluations of the Nurotron Venus cochlear implant system via animal experiments and clinical trials.

    abstract:CONCLUSION:This study described objective and subjective evaluations of the Nurotron® Venus™ Cochlear Implant System and indicated that this system produced a satisfactory performance. OBJECTIVE:To observe the performance of the Nurotron® Venus™ cochlear implant (CI) system via electrophysiological and psychophysical ...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.3109/00016489.2015.1086022

    authors: Gao N,Xu XD,Chi FL,Zeng FG,Fu QJ,Jia XH,Yin YB,Ping LC,Kang HY,Feng HH,Wu YZ,Jiang Y

    更新日期:2016-01-01 00:00:00

  • Cystine protects cochlear outer hair cells against glutamate toxicity.

    abstract::We previously reported that long-term exposure to glutamate (Glu) induced death of cochlear outer hair cells (OHCs). However, the mechanisms of OHC death induced by Glu were unclear. In the central nervous system, Glu is known to interfere with a cystine-Glu antiporter, leading to a decrease in cystine uptake and redu...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.1080/00016489950180612

    authors: Sunami K,Yamane H,Takayama M,Nakagawa T,Konishi K,Iguchi H

    更新日期:1999-01-01 00:00:00

  • Hearing fluctuation during migraine attacks. Activity of propranolol-HCl in rats.

    abstract::Transitory hearing impairment has been well documented in humans during basilar migraine attacks. Ischemia induced by activation of central nervous system adrenoreceptors by cAMP is one of the mechanisms that has been implicated, as well as calcium metabolism alterations. Propranolol-HCl has proven to be an effective ...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.3109/00016489109137383

    authors: Bernard PA,Bourret CS,Stenstrom R

    更新日期:1991-01-01 00:00:00

  • Induction of MUC5AC mucin expression by histamine through the activation of its core promoter region.

    abstract:CONCLUSION:This study provides evidence that histamine induced MUC5AC mRNA expression through the activation of the core region of its promoter. It may also help in approaching new therapeutic strategies in airway mucins hypersecretory diseases. OBJECTIVE:Mucin hypersecretion characterizes several respiratory diseases...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.3109/00016489.2015.1017890

    authors: Xu F,Zhang L,Gao J,Wang D

    更新日期:2015-07-01 00:00:00

  • MicroRNA-21 promotes the proliferation and invasion of cholesteatoma keratinocytes.

    abstract:CONCLUSIONS:The present study revealed that miR-21 promotes the proliferation and invasion of cholesteatoma keratinocytes. These results provide a partial explanation for the more aggressive clinical behavior observed in cholesteatoma. OBJECTIVE:This study aims to investigate the post-transcriptional regulatory effect...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.1080/00016489.2016.1202447

    authors: Chen X,Li X,Qin Z

    更新日期:2016-12-01 00:00:00

  • Evaluation of mutations in penicillin binding protein-3 gene of non-typeable Haemophilus influenzae isolated from the nasopharynx of children with acute otitis media.

    abstract:CONCLUSION:Younger children tend to harbor more resistant strains because they are exposed to these pathogens more often through contacts with siblings or attendance at day-care centers and are frequently treated with antibiotics. The high prevalence of BLNAR strains should be taken into account in the treatment of AOM...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.1080/00016480410020301

    authors: Sakai A,Hotomi M,Billal DS,Yamauchi K,Shimada J,Tamura S,Fujihara K,Yamanaka N

    更新日期:2005-02-01 00:00:00

  • Comparison of preoperative and postoperative radiation therapy for patients with carcinoma of the head and neck. Interim report.

    abstract::Three hundred and fifty-four patients with squamous cell carcinoma of the oral cavity, oropharynx, supraglottic larynx, hypopharynx or maxillary sinus have been randomized for preoperative radiation therapy and surgery versus surgery and postoperative radiation therapy plus, in the case of patients with lesions of the...

    journal_title:Acta oto-laryngologica

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.3109/00016488109138548

    authors: Snow JB,Gelber RD,Kramer S,Davis LW,Marcial VA,Lowry LD

    更新日期:1981-05-01 00:00:00

  • Indications of cone beam CT in head and neck imaging.

    abstract:CONCLUSION:Cone Beam Computed Tomography (CBCT) can be widely used in imaging of bony structures of the anterior and lateral skull base. Significant differences of applied dosages result from the different protocols of the various indications. OBJECTIVES:CBCT is increasingly being used in head and neck imaging. Until ...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.3109/00016489.2015.1076172

    authors: Stutzki M,Jahns E,Mandapathil MM,Diogo I,Werner JA,Güldner C

    更新日期:2015-01-01 00:00:00

  • The vestibular blood flow during CO2-breathing in rabbits.

    abstract::The microsphere method was used to measure the inner ear blood flow in albino rabbits before and during artificial ventilation with 5% CO2 in air. An increase in blood flow resulted in both the cochlear and the vestibular parts of the inner ear. ...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.3109/00016488709134692

    authors: Larsen HC,Angelborg C

    更新日期:1987-01-01 00:00:00