Early timing of low-dose dexamethasone decreases inflammation in a murine model of eosinophilic airway disease.

abstract：:Hereditary angioneurotic edema (HAE) is an autosomal dominant disease resulting from a deficiency of functional C1-esterase inhibitor. If not recognized promptly and treated properly the disease can result in a fatal outcome as it causes laryngeal edema, which can lead to a life-threatening acute upper airway obstruct...

journal_title：Acta oto-laryngologica

authors： Lim YC,Kim JK,Shim DB,Lim CH,Jang HJ,Shin HA,Choi EC

更新日期：2005-11-01 00:00:00

abstract：:Beta 2-microglobulin (beta 2m) is a small polypeptide, related to the immunoglobulins and present on nucleated cells as part of the strong transplantation antigens. Elevated plasma levels have been recorded in patients with various malignant diseases. Human beta 2m has also been detected immunohistochemically in carci...

journal_title：Acta oto-laryngologica

authors： Wennerberg J,Alm P,Lögdberg L,Tropé C

更新日期：1984-09-01 00:00:00

abstract：:We examined the serial changes of intravenously applied dye leakage and preliminary examined histamine release into nasal lavage fluid after topical stimulation with capsaicin in guinea pigs. A significant increase in the dye leakage response was detected for 30-40 min, with the maximum response occurring between 5 an...

journal_title：Acta oto-laryngologica

authors： Asakura K,Shirasaki H,Narita S,Kojima T,Kataura A

更新日期：1992-01-01 00:00:00

abstract：:Nasal polyps is a chronic inflammatory disease of the upper airway characterized by structural abnormalities including stromal fibrosis. Fibroblasts are a rich source of cytokines and inflammatory mediators and are thought to play an important role in the development of fibrosis. In addition, there is considerable evi...

journal_title：Acta oto-laryngologica

authors： Nonaka M,Pawankar R,Saji F,Yagi T

更新日期：1999-01-01 00:00:00

abstract：:On-line measurement of ME gas composition in normal middle ears of 5 anesthetized guinea pigs at an established steady state was performed by mass spectrometry. The mean values for the gas composition of the middle ear were found to be: PN2: 82.4%, PO2: 7.6% and PCO2: 10.0%. This composition is very different from tha...

journal_title：Acta oto-laryngologica

authors： Sadé J,Luntz M

更新日期：1993-05-01 00:00:00

abstract：:The treatment of acute otitis media was studied in 158 children. All children (mean age 4 years) received penicillin orally 80 000--100 000 IU per day for 10 days. Myringotomy was performed on 68 children at the time of the diagnosis. The other 90 children were treated with penicillin and ear drops. The bacteriologica...

journal_title：Acta oto-laryngologica

authors： Puhakka H,Virolainen E,Aantaa E,Tuohimaa P,Eskola J,Ruuskanen O

更新日期：1979-01-01 00:00:00

abstract：CONCLUSION:The possible roles of CD44st, CD44v5 and CD44v6 in the prognosis of head and neck cancer deserve further elucidation and evaluation with long-term patient follow-up. OBJECTIVE:Standard CD44 (CD44st), CD44 variant 5 (CD44v5) and CD44 variant 6 (CD44v6) are expressed in human malignant cells and tissues. The ...

journal_title：Acta oto-laryngologica

authors： Kawano T,Yanoma S,Nakamura Y,Ozeki A,Kokatsu T,Kubota A,Furukawa M,Tsukuda M

更新日期：2005-04-01 00:00:00

abstract：BACKGROUND:Intratympanic corticosteroid (IC), intravenous batroxobin (IB) as the treatment for sudden sensorineural hearing loss (SSNHL) has been reported. However, the data on combination therapy (CT) was scarce. OBJECTIVE:The aim of this retrospective study was to compare the efficacy of IC, IB, and CT in the treatm...

journal_title：Acta oto-laryngologica

authors： Jia H,Yu Z,Li X,Wang J,Ge X,Chen ZT,Huang X,Wei Y

更新日期：2019-06-01 00:00:00

abstract：CONCLUSION:The technology of stimulation rates between 1500 and 5000 pulses per second per channel (pps/ch) brings a benefit for all users. However, the fastest possible rate does not necessarily lead to best hearing performance in each individual subject. Individual optimization of stimulation rate is recommended. OB...

journal_title：Acta oto-laryngologica

authors： Buechner A,Frohne-Büchner C,Gaertner L,Stoever T,Battmer RD,Lenarz T

更新日期：2010-01-01 00:00:00

abstract：:We recently reported the development of a cell line, AMC-HN-9, established from an undifferentiated carcinoma (UDC) of the parotid gland. AMC-HN-9 consists mostly of spindle-shaped cells, has poor in vitro adhesiveness and an in vitro appearance that is different from that of other epithelial cell lines. To test the h...

journal_title：Acta oto-laryngologica

authors： Kim SH,Carey TE,Liebert M,Yoo SJ,Kwon HJ,Kim SY

更新日期：2000-08-01 00:00:00

abstract：:This study aimed to investigate whether unilateral vestibular neuritis (VN) causes the same deficits of ocular counter-roll during static head roll (OCR(S)) and dynamic vestibulo-ocular reflex gains during head impulses (VOR(HI)) as unilateral vestibular deafferentation (VD). Ten patients with acute and 14 patients wi...

journal_title：Acta oto-laryngologica

authors： Schmid-Priscoveanu A,Straumann D,Böhmer A,Obzina H

更新日期：1999-01-01 00:00:00

abstract：BACKGROUND:Endolymphatic sac decompression has shown limited success for the treatment of Ménière's disease (MD). We have published a novel technique with very promising results for the treatment of refractory MD: the Endolymphatic Duct Blockage (EDB) with two titanium clips. One of the challenges of this technique was...

journal_title：Acta oto-laryngologica

authors： Saliba I,Asmar MH

更新日期：2018-10-01 00:00:00

abstract：:The view current over the last 60 years or so that coniotomy often leads to subglottic stenosis has recently been called into question. In the present study 103 electively performed coniotomies have been analysed. The operation was found to be much easier than tracheotomy. There was no case of severe peroperative or p...

journal_title：Acta oto-laryngologica

authors： Holst M,Hedenstierna G,Kumlien JA,Schiratzki H

更新日期：1983-09-01 00:00:00

abstract：:The purpose of this paper was to establish a mammalian comparative study between the neuronal spaces of the upper versus the basal cochlear turns. We studied with light microscopy i) Webster albino rat embryos at various gestational days (GD), and a postnatal (PN) series; ii) kittens 3 weeks old; iii) pigmented guinea...

journal_title：Acta oto-laryngologica

authors： Sánchez-Fernández JM,Sánchez-del Rey A,Santaolalla-Montoya F,Martinez Ibarguen A

更新日期：1997-03-01 00:00:00

abstract：CONCLUSIONS:Increased expression of Dicer may be a prognostic biomarker for patients with laryngeal squamous cell carcinoma (LSCC). OBJECTIVES:Recent studies have shown that many microRNAs (miRNAs) play an important role in the development and progression of human cancers. Dicer, one of the most important enzymes of t...

journal_title：Acta oto-laryngologica

authors： Gao C,Li X,Tong B,Wu K,Liu Y,Anniko M,Duan M

更新日期：2014-09-01 00:00:00

abstract：:Characteristic patterns of laryngeal dysfunction due to central neurologic disease are documented by 16 mm ciné photography. Representative patients are used to describe typical patterns of abnormal laryngeal function which occur in upper motor neuron, extrapyramidal, cerebellar, nuclear and mixed foci of lesions. The...

journal_title：Acta oto-laryngologica

authors： Ward PH,Hanson DG,Berci G

更新日期：1981-05-01 00:00:00

abstract：:The distribution of vascular endothelial growth factor (VEGF), one of the most important angiogenic factors, and microvessel density (MVD) were assessed in laryngeal carcinomas by means of immunohistochemistry. Correlation of VEGF with MVD and clinical parameters (T stage, N stage, histological grading, survival, recu...

journal_title：Acta oto-laryngologica

authors： Neuchrist C,Quint C,Pammer A,Burian M

更新日期：1999-01-01 00:00:00

abstract：:The aerobic and anaerobic bacterial flora of middle ear exudate (MEE) of 47 consecutive patients with chronic suppurative otitis media were studied using a quantitative bacteriological technique under strictly anaerobic conditions. Specimens from the external auditory canal (EAC) and the nasopharynx (NP) were obtained...

journal_title：Acta oto-laryngologica

authors： Jonsson L,Schwan A,Thomander L,Fabian P

更新日期：1986-11-01 00:00:00

abstract：CONCLUSIONS:Local administration of MP delivered by the C/GP-MP-hydrogel can improve the recovery of facial nerve following crush injury. The findings suggested that locally injected MP delivered by C/GP-hydrogel might be a promising treatment for facial nerve damage. OBJECTIVES:In this study, the aim is to assess the...

journal_title：Acta oto-laryngologica

authors： Chao X,Fan Z,Han Y,Wang Y,Li J,Chai R,Xu L,Wang H

更新日期：2015-01-01 00:00:00

abstract：:T lymphocytes from tonsil (To) and peripheral blood (PB) of 4 tonsillectomized children were subjected to clonal expansion with PHA in order to analyze at single cell level their cytolytic activity and their ability to produce interleukins such as IL-2, IFN-gamma and IL-4. Analyzing all T-cell clones (CD4+ and CD8+) o...

journal_title：Acta oto-laryngologica

authors： Gallo O,De Carli M,Gallina E,Toccafondi G,Romagnani S,Del Prete G

更新日期：1991-01-01 00:00:00

abstract：CONCLUSION:Patients with hiatus hernia can be relieved from H, MSL and MSN by hiatus hernia repair. OBJECTIVE:It has been hypothesized that respiratory symptoms in patients with gastro-oesophageal reflux disease (GORD) may, in some cases, be due to misdirected swallowing as a consequence of defective opening of the up...

journal_title：Acta oto-laryngologica

authors： Mjönes AB,Ledin T,Grahn LT,Hultcrantz E

更新日期：2005-01-01 00:00:00

abstract：:The facial nerve of the albino rat was compressed by inserting a thin nylon thread in the facial canal. After a survival period of 1-60 days, the animal was perfused with Ringer's solution followed by a 2% periodate-lysine-paraformaldehyde fixative. Frozen sections from the brain stem containing the facial motor nucle...

journal_title：Acta oto-laryngologica

authors： Ruan RS,Leong SK,Yeoh KH

更新日期：1994-05-01 00:00:00

abstract：:Reserpine (2 mg/kg and 10 mg/kg, i.p.), an adrenergic blocker, was administered to normal guinea pigs, and samples of serum, CSF, scala tympani perilymph, scala vestibuli perilymph and cochlear endolymph were collected. The concentrations of Na and K in these fluids were then assessed to observe electrolyte distributi...

journal_title：Acta oto-laryngologica

authors： Kanoh N,Makimoto K

更新日期：1984-07-01 00:00:00

abstract：:Vestibular microphonics in response to acoustical stimulation were recorded in cochlea-deprived pigeons. Endolymph flow in the semicircular canals alters this response. A caloric stimulus was applied to the horizontal canal or the posterior vertical canal close to the ampulla. To minimize the influence of gravity, the...

journal_title：Acta oto-laryngologica

authors： Wit HP,Segenhout JM

更新日期：1988-03-01 00:00:00

abstract：BACKGROUND:pH monitoring can reflect the changes in H+ in the airway. OBJECTIVES:To explore the utility of pharyngeal pH monitoring in the diagnosis of laryngopharyngeal reflux disease (LPRD). MATERIAL AND METHODS:Clinical data from 956 suspected LPRD patients from February 2016 to March 2018 were analyzed retrospect...

journal_title：Acta oto-laryngologica

authors： Wang G,Qu C,Wang L,Liu H,Han H,Xu B,Zhou Y,Li B,Zhang Y,Sun Z,Gong J,Li L,Wu W

更新日期：2019-03-01 00:00:00

abstract：:Conclusion Eustachian tube (ET) dysfunction, which plays a role in the pathogenesis chronic suppurative otitis media (CSOM), does not seem to be due to differences in paratubal structures. Objective The aim of this study was to compare the magnetic resonance imaging (MRI) findings of the paratubal structures of the ET...

journal_title：Acta oto-laryngologica

authors： Terzi S,Beyazal Çeliker F,Özgür A,Çeliker M,Beyazal M,Demirci M,Dursun E

更新日期：2016-07-01 00:00:00

abstract：OBJECTIVE:To quantitatively analyze modifications of the paratubal muscles in developing Wistar rats following nasal obstruction. MATERIAL AND METHODS:Twenty-four Wistar rats were used. Twelve were examined at 6, 8 and 12 weeks after birth and were considered normal controls. The nostrils of the remaining 12 rats were...

journal_title：Acta oto-laryngologica

authors： Scarano E,Fetoni AR,Picciotti P,Cadoni G,Galli J,Paludetti G

更新日期：2003-01-01 00:00:00

abstract：:The objective of the present study was to establish the estimated incidence of symptomatic nasal polyps within a defined geographic area. Over a 6-year period all polyp patients diagnosed for the first time (n = 252; 174 males, 78 females) were prospectively registered at the study clinic. An estimated background popu...

journal_title：Acta oto-laryngologica

authors： Larsen K,Tos M

更新日期：2002-03-01 00:00:00

abstract：CONCLUSION:We demonstrated an early increase in aquaporin 2 (AQP2) expression in a motor nerve (extratemporal facial nerve, FN) following acute peripheral compression (crush), concomitant to effective development of motor dysfunction (facial palsy). The early increase in AQP2 expression that occurred concomitantly with...

journal_title：Acta oto-laryngologica

authors： Neiva FC,Borin A,Lee KS,Dias MV,Rodrigues BR,Testa JR,Cruz OL,Covolan L

更新日期：2015-07-01 00:00:00

abstract：CONCLUSIONS:A large series confirmation may suggest elective neck dissection in cN0 MASPIN-negative oral squamous cell carcinomas (SCCs). Re-activated nuclear MASPIN in association with anti-angiogenic or cytotoxic drugs may be extremely effective in the treatment of laryngeal SCC. OBJECTIVES:MASPIN is a serpin showin...

journal_title：Acta oto-laryngologica

authors： Marioni G,Staffieri C,Staffieri A,De Filippis C,Blandamura S

更新日期：2009-05-01 00:00:00