Simultaneous and non-simultaneous dual electrode stimulation in cochlear implants: evidence for two neural response modalities.

abstract：:The MRL/lpr mouse, which is homozygous for the recessive lpr genes and has a mutation in the Fas gene encoding a cell-surface receptor for apoptosis, exhibits severe lymphadenopathy and develops systemic lupus erythematosus (SLE)-like disease. It has recently been reported that this mouse also manifests sensorineural ...

journal_title：Acta oto-laryngologica

authors： Iwai H,Lee S,Baba S,Tomoda K,Inaba M,Ikehara S,Yamashita T

更新日期：2004-01-01 00:00:00

abstract：CONCLUSIONS:Local administration of MP delivered by the C/GP-MP-hydrogel can improve the recovery of facial nerve following crush injury. The findings suggested that locally injected MP delivered by C/GP-hydrogel might be a promising treatment for facial nerve damage. OBJECTIVES:In this study, the aim is to assess the...

journal_title：Acta oto-laryngologica

authors： Chao X,Fan Z,Han Y,Wang Y,Li J,Chai R,Xu L,Wang H

更新日期：2015-01-01 00:00:00

abstract：CONCLUSIONS:The critical stage for cochlear gene regulation in the embryo is E49-E56. These data provide a valuable resource to help elucidate gene regulation in cochlear development and will benefit ear-related studies, especially those that focus on gene and stem cell therapies in hearing loss. OBJECTIVES:To investi...

journal_title：Acta oto-laryngologica

authors： Wang Q,Zhang Y,Guo W,Liu Y,Wei H,Yang S

更新日期：2017-11-01 00:00:00

abstract：:POLGON (Polarized light goniometer) was used to evaluate ataxia during stepping movements in patients with spinocerebellar degeneration (SCD) and Parkinson's disease. The measurements included mean angular change of shoulders (M.A.C.S.) and its coefficient of variation (C.V.). In patients with SCD, the values of M.A.C...

journal_title：Acta oto-laryngologica

authors： Sasaki O,Taguchi K,Kikukawa M,Ogiba T

更新日期：1993-07-01 00:00:00

abstract：CONCLUSION:These findings indicate a strong protective effect of ALCAR and NAC on impulse noise-induced cochlear damage, and suggest the feasibility of using clinically available antioxidant compounds to protect the ear from acute acoustic injury. OBJECTIVE:Reactive oxygen species have been shown to play a significant...

journal_title：Acta oto-laryngologica

authors： Kopke R,Bielefeld E,Liu J,Zheng J,Jackson R,Henderson D,Coleman JK

更新日期：2005-03-01 00:00:00

abstract：:A questionnaire was devised to quantify and measure four categories: the behavioral characteristics of Type A, self-restraint and escape; the causes of anxiety; means of relaxation; and symptoms incidental to anxiety. Questionnaire analysis was performed in patients (n = 60) with Meniere's disease and in a control pop...

journal_title：Acta oto-laryngologica

authors： Takahashi M,Ishida K,Iida M,Yamashita H,Sugawara K

更新日期：2001-01-01 00:00:00

abstract：CONCLUSION:SOD1 is an important gene related to noise-induced hearing loss (NIHL), and its effect is dependent on noise exposure levels. OBJECTIVES:To test whether the polymorphisms in the CuZn-superoxide dismutase gene (SOD1) are associated with susceptibility to NIHL in the Chinese population. METHODS:Audiometric d...

journal_title：Acta oto-laryngologica

authors： Liu YM,Li XD,Guo X,Liu B,Lin AH,Rao SQ

更新日期：2010-04-01 00:00:00

abstract：:In consecutive series of 326 laryngeal cancer patients, of 29 (9%) with stage T3N0 glottic carcinomas, 23 achieved complete local remission after curative radiotherapy and form the basis of the present investigation. Flow cytometry determinations of DNA-ploidy status and the S-phase fraction, and a "histopathological ...

journal_title：Acta oto-laryngologica

authors： Tennvall J,Wennerberg J,Willén R,Ask A,Baldetorp B,Fernö M

更新日期：1993-03-01 00:00:00

abstract：UNLABELLED:Abstract Conclusion: The selected scFv antibody could specifically recognize and target nasopharyngeal carcinoma (NPC), and could be applied to clinical diagnosis and therapy. OBJECTIVE:The aim was to construct and screen fully human anti-NPC single chain Fv fusion phage libraries, and to identify the sp...

journal_title：Acta oto-laryngologica

authors： Li YD,Li YH,Zhao Y,Wang JJ,Xie PL,Guo FJ,Ren CP,Li GC

更新日期：2012-06-01 00:00:00

abstract：:Enzymatic tracer techniques to study normal and pathologic strial capillary transport pose various problems. The use of electron opaque tracers can circumvent many of these problems. Iron dextran (mol. diam 20--70 A) and ferritin (mol. diam 110 A) were injected intravenously and the mice sacrificed at intervals of 1/2...

journal_title：Acta oto-laryngologica

authors： Santos-Sacchi J,Marovitz WF

更新日期：1980-01-01 00:00:00

abstract：:Most epidemiological surveys concerning populations exposed to occupational noise or random populations have shown that the left ear is slightly but significantly poorer than the right ear, especially at frequencies most susceptible to noise damage. To experimentally study the possible left-right asymmetry in response...

journal_title：Acta oto-laryngologica

authors： Pirilä T

更新日期：1991-01-01 00:00:00

abstract：:The influence of neck and leg proprioceptive inputs on optokinetic-induced quick phases was studied in humans. Ten subjects received unidirectional horizontal optokinetic stimulation (10-20%/s) during sinusoidal neck, leg and combined neck + leg proprioceptive stimulation. The optokinetic reflex was measured by electr...

journal_title：Acta oto-laryngologica

authors： Botti F,Anastasopoulos D,Kostadima V,Bambagioni D,Pettorossi VE

更新日期：2001-01-01 00:00:00

abstract：CONCLUSIONS:Cyclo-oxygenase-2 (COX-2) enzyme would not appear to be constitutively expressed in human perilymph while it is always induced in the perilymph of patients affected by sensorineural hearing loss (SNHL). The COX-2 isoform may be involved in hearing loss and, therefore, pathological states of the inner ear sh...

journal_title：Acta oto-laryngologica

authors： Attanasio G,Viccaro M,Covelli E,De seta E,Minni A,Pizzoli F,Filipo R

更新日期：2011-03-01 00:00:00

abstract：:The occurrence of artifactual morphological changes was investigated in human eighth nerve biopsies and corresponding changes were brought about in biopsies from rats by mechanical handling before fixation. At the very site of compression by a pair of forceps the biopsy stained lighter than in its immediate surroundin...

journal_title：Acta oto-laryngologica

authors： Collan Y,Ylikoski J,Palva T,Selamaa R

更新日期：1980-01-01 00:00:00

abstract：:Volumetric changes of the scala media were histologically investigated in normal guinea pigs to see whether glycerol-induced volumetric change of the scala media followed a biphasic course similar to the auditory threshold in the glycerol test. Glycerol was administered orally in a 12 ml/kg dose. The volume of the sca...

journal_title：Acta oto-laryngologica

authors： Takeda T,Takeda S,Saito H,Hamada M,Sawada S

更新日期：1999-01-01 00:00:00

abstract：CONCLUSION:The endoscopic transnasal approach with IGS is a safe and effective technique, allowing completely resection of JPOF, with minimal morbidity and recurrence. OBJECTIVES:JPOF is a benign but locally aggressive fibro-osseous lesion. This study presents a series of JPOF cases, involving anterior skull base and ...

journal_title：Acta oto-laryngologica

authors： Wang M,Zhou B,Cui S,Li Y

更新日期：2017-07-01 00:00:00

abstract：:By using the microsuction technique, quantitative determination of the chemical mediators in nasal secretions was performed in 40 patients with seasonal allergic rhinitis during the pollen season. The aim of this study was to investigate the actual concentrations of these important mediators in nasal secretions during...

journal_title：Acta oto-laryngologica

authors： Wang D,Clement P,Smitz J,Derde MP

更新日期：1994-09-01 00:00:00

abstract：CONCLUSION:Extensive bone erosion correlated with a worse prognosis of the squamous cell carcinoma (SCC) of the temporal bone but extensive soft tissue involvement did not correlate with prognosis in this study. Resectability of the tumor seems to be major prognostic factor of temporal bone SCC. OBJECTIVE:Prognostic f...

journal_title：Acta oto-laryngologica

authors： Ito M,Hatano M,Yoshizaki T

更新日期：2009-11-01 00:00:00

abstract：:This study was performed in order to determine the immunohistochemical expression and distribution pattern as well as the electrophysiological actions of substance P in human vestibular ganglion cells. Substance P-like immunostaining was mainly found in the cytoplasm of small vestibular ganglion cells. In contrast, ne...

journal_title：Acta oto-laryngologica

authors： Felix H,Schickinger B,Felix D

更新日期：1996-03-01 00:00:00

abstract：:Spiral ganglia of guinea pig and mouse were investigated by scanning electron microscopy (SEM). The cochlea was freeze-fractured and then macerated with 0.1% OsO4 solution for 70-90 h (A-O-D-O method (1]. This allowed three-dimensional observation of the general view of the spiral ganglion and the intracellular struct...

journal_title：Acta oto-laryngologica

authors： Harada Y,Nagasawa A,Takumida M,Tagashira N,Hirakawa K,Suzuki M

更新日期：1989-05-01 00:00:00

abstract：:During the development of the mammalian inner ear, the number of hair cells produced is highly regulated and remains constant throughout life. The mechanism underlying this regulation is beginning to be understood although many aspects still remain obscure. When late embryonic or early postnatal rat organs of Corti we...

journal_title：Acta oto-laryngologica

authors： Lefebvr PP,Malgrange B,Thiry M,Breuskin I,Van De Water TR,Moonen G

更新日期：2001-01-01 00:00:00

abstract：:The ultrastructure of the geniculate ganglion was studied in the guinea pig and monkey. Two cytologically distinct colonies of ganglion cells were seen and identified as light and dark cells. All neurons were unmyelinated and most were unipolar, although a few bipolar cells were seen. The axons, upon leaving the cell ...

journal_title：Acta oto-laryngologica

authors： Kitamura K,Kimura RS,Schuknecht HF

更新日期：1982-01-01 00:00:00

abstract：CONCLUSION:The improved biocompatibility of Bioverit II coated with a nanostructured surface shows promising qualities for use in human reconstructive middle ear surgery. In the case of chitosan-hydroxyapatite composite prostheses, further investigations regarding composition of the material, degree of purity and desig...

journal_title：Acta oto-laryngologica

authors： Turck C,Brandes G,Krueger I,Behrens P,Mojallal H,Lenarz T,Stieve M

更新日期：2007-08-01 00:00:00

abstract：CONCLUSION:The clinical presentation and outcome of post-traumatic benign paroxysmal positional vertigo (t-BPPV) are different from those idiopathic BPPV (i-BPPV). It appears that t-BPPV is more difficult to treat than i-BPPV. OBJECTIVE:To identify the clinical presentation and outcome of t-BPPV. METHODS:We reviewed ...

journal_title：Acta oto-laryngologica

authors： Liu H

更新日期：2012-08-01 00:00:00

abstract：CONCLUSION:The increased AQP5 expression associated with ageing in glands, which mainly secreted a serous solution, suggests a compensation for the decreased amount of saliva secretion associated with age progression. OBJECTIVE:To investigate the change in aquaporin-1 (AQP1) and aquaporin-5 (AQP5) expression in the sa...

journal_title：Acta oto-laryngologica

authors： Sapmaz E,Uysal M,Tumer MK,Sapmaz HI,Somuk BT,Arici A,Tas U

更新日期：2016-09-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to analyze the safety and effectiveness of a new cochlear implant (CI) system developed in China, the Nurotron Venus device. MATERIAL AND METHODS:Fifteen post-lingually deafened patients received Nurotron Venus CIs in our hospital. The safety and effectiveness of the devices were ev...

journal_title：Acta oto-laryngologica

authors： Li J,Ji F,Chen W,Zhao H,Han D,Yang S

更新日期：2014-06-01 00:00:00

abstract：:The efferent cochlear system, composed of both ipsi- and contralateral bundles, runs along with the vestibular nerve and may serve as protection for the inner ear. Sectioning of the vestibular nerve could thus create an experimental model for further in-depth study of such a protective role. A personal surgical approa...

journal_title：Acta oto-laryngologica

authors： Barbara M,Attanasio G,Piccoli F,Filipo R

更新日期：1999-03-01 00:00:00

abstract：:The sympathetic nerve pathways to the nasal vasculature were examined in 8 cats by recoding the effects of section of the orbital nerves on vasoconstriction produced by cervical sympathetic nerve stimulation. No sympathetic fibres were found in the sphenopalatine and infraorbital nerves. The majority were conveyed by ...

journal_title：Acta oto-laryngologica

authors： Wilson H,Yates MS

更新日期：1977-09-01 00:00:00

abstract：CONCLUSION:The average recovery of hearing and cessation of tinnitus was significantly better after treatment with Radix Astragali (RA) than after non-treatment with RA. RA can be valuable adjuvant therapy for patients with acute acoustic trauma (AAT). OBJECTIVES:AAT is one of the early indications for the use of RA. ...

journal_title：Acta oto-laryngologica

authors： Xiong M,He Q,Lai H,Huang W,Wang L,Yang C,Wang J

更新日期：2011-10-01 00:00:00

abstract：BACKGROUND:To identify the difference of surgical margin and recurrence status of early stage tongue carcinoma via wide excision in a single institution with and without free flap reconstruction. OBJECTIVE:Survey whether the reconstruction methods for early tongue cancer affects disease control, survival outcomes. ME...

journal_title：Acta oto-laryngologica

authors： Lu CC,Tsou YA,Hua CH,Tsai MH

更新日期：2018-10-01 00:00:00