Preparation of human scFv antibody against nasopharyngeal carcinoma and identification of its specificity.

abstract：CONCLUSION:Cochleostomy is the most efficient approach in delivering PEG-b-PCL polymersomes (PMs) to the inner ear. PMs can be delivered to the vestibule by transtympanic injection or cochleostomy. OBJECTIVE:To evaluate the efficiency of delivering PEG-b-PCL PMs into the inner ear using different approaches. METHODS:...

journal_title：Acta oto-laryngologica

authors： Zhang Y,Zhang W,Johnston AH,Newman TA,Pyykk I,Zou J

更新日期：2011-12-01 00:00:00

abstract：CONCLUSION:It is thought that oxidative stress may be the major cause of the increase in the oxide thiol form in the study group. The relationship between oxidative stress status and dynamic thiol/disulphide in nasal polyposis now needs to be investigated. OBJECTIVES:The purpose of this study was to evaluate the relat...

journal_title：Acta oto-laryngologica

authors： Şimşek E,Erel O,Bicer CK,Çarlıoğlu A

更新日期：2016-11-01 00:00:00

abstract：CONCLUSIONS:The risk factors for methicillin-resistant Staphylococcus aureus (MRSA) detection in head and neck cancer patients are the duration of hospitalization, intravenous hyperalimentation, prior antibiotic use, and the coexistence of other pathogens. OBJECTIVES:To shed light on the clinical characteristics of MR...

journal_title：Acta oto-laryngologica

authors： Shiomori T,Miyamoto H,Udaka T,Okochi J,Hiraki N,Hohchi N,Hashida K,Fujimura T,Kitamura T,Nagatani G,Ohbuchi T,Suzuki H

更新日期：2007-02-01 00:00:00

abstract：BACKGROUND:Intratympanic corticosteroid (IC), intravenous batroxobin (IB) as the treatment for sudden sensorineural hearing loss (SSNHL) has been reported. However, the data on combination therapy (CT) was scarce. OBJECTIVE:The aim of this retrospective study was to compare the efficacy of IC, IB, and CT in the treatm...

journal_title：Acta oto-laryngologica

authors： Jia H,Yu Z,Li X,Wang J,Ge X,Chen ZT,Huang X,Wei Y

更新日期：2019-06-01 00:00:00

abstract：:We investigated the effect of prolonged hypergravity on the otoconial layer of the maculae utriculi and the maculae sacculi in hamsters. The animals were placed in a centrifuge under conditions of 2.5 G, and remained there for 6 months. We then determined the calcium contents of the otoconia with energy dispersive X-r...

journal_title：Acta oto-laryngologica

authors： Sondag HN,de Jong HA,van Marle J,Oosterveld WJ

更新日期：1995-03-01 00:00:00

abstract：:Assessment of hearing handicap is frequently based on hearing loss in the frequency region from 0.5 to 2.0 kHz. The region above 2 kHz, however, is important for hearing, particularly when one considers speech perception in conditions with ambient noise. The present study, based on 200 individuals (400 ears) with nois...

journal_title：Acta oto-laryngologica

authors： Smoorenburg GF

更新日期：1990-01-01 00:00:00

abstract：:As a continuation of our previous work, where we have demonstrated that in chronic otitis media the picture in the submucosa-bone marginal zone is dominated by capillary proliferation and occurrence of a mononuclear, histiocyte-like cell containing lysosome-like cytoplasmatic bodies, we now report the presence of cons...

journal_title：Acta oto-laryngologica

authors： Thomsen J,Bretlau P,Kristensen HK

更新日期：1975-05-01 00:00:00

abstract：CONCLUSIONS:Polytetrafluoroethylene (PTFE) may represent a material that prevents adhesions when implanted in the middle ear. This characteristic can be used to improve the design of prostheses. OBJECTIVE:Prostheses in the middle ear have a relatively high failure rate due to extrusion, deformation and adhesion. Adhes...

journal_title：Acta oto-laryngologica

authors： Vicente J,Ramírez-Camacho R,Trinidad A,Ramón García-Berrocal J,Lobo D,Pinilla M

更新日期：2006-02-01 00:00:00

abstract：:Vascularization between vestibular schwannomas and the adjacent eighth cranial nerve was examined in order to elucidate the angiogenic effect of these tumours. Specimens from 12 patients were examined by light microscopy and immunohistochemistry (series 1), while specimens from another 17 patients were examined by lig...

journal_title：Acta oto-laryngologica

authors： Matsunaga T,Kanzaki J,Hosoda Y

更新日期：1996-01-01 00:00:00

abstract：CONCLUSIONS:The procedure cleared the lesion completely and preserved the physiological function of the external auditory canal. OBJECTIVE:To develop a novel surgical procedure to treat chronic suppurative otitis media (CSOM). To explore the merit of using pedicled temporalis myofascia (PTM) and reconstruction of the ...

journal_title：Acta oto-laryngologica

authors： Yu F

更新日期：2013-07-01 00:00:00

abstract：:Phoniatric and acoustic examinations were carried out in a group of 30 patients with dysphonia, including 15 with organic type and 15 with functional type. A complex phoniatric assessment offered the possibility to differentiate between these two groups of pathological voices. This was achieved also on the basis of ac...

journal_title：Acta oto-laryngologica

authors： Pruszewicz A,Obrebowski A,Swidziński P,Demeńko G,Wika T,Wojciechowska A

更新日期：1991-01-01 00:00:00

abstract：:This study correlates static and flow-cytometric analysis on paraffin-embedded and fresh material of salivary gland carcinomas. Nuclear suspensions for DNA analysis were prepared from paraffin-embedded and fresh material. Comparison of the results of static and flow cytometry on paraffin-embedded material revealed no ...

journal_title：Acta oto-laryngologica

authors： Nordgård S,Franzén G,Boysen M,Tytor M

更新日期：1999-01-01 00:00:00

abstract：CONCLUSIONS:Proteases in fungi interact with nasal epithelial cells and enhance the production of inflammatory cytokines in vitro. These cytokines induced the migration of eosinophils and neutrophils. Protease-activated receptors (PARs) might also play a role in the process of epithelial cell activation. OBJECTIVE:The...

journal_title：Acta oto-laryngologica

authors： Shin SH,Lee YH,Jeon CH

更新日期：2006-12-01 00:00:00

abstract：CONCLUSION:Our results suggest that hepatocyte growth factor (HGF) may play an important role in the progression of hypopharyngeal cancer. OBJECTIVE:HGF, a potent stimulator of hepatocyte growth, stimulates the motility, invasiveness, proliferation and morphogenesis of epithelium and may be involved in physiologic and...

journal_title：Acta oto-laryngologica

authors： Kim CH,Moon SK,Bae JH,Lee JH,Han JH,Kim K,Choi EC

更新日期：2006-01-01 00:00:00

abstract：BACKGROUND:ABO blood group status may be a risk factor for some diseases, including hearing loss. Individuals with blood group O show a higher prevalence of hearing loss after industrial noise exposure. Group O individuals with normal hearing show reduced amplitudes in otoacoustic emission recordings. Whether blood gro...

journal_title：Acta oto-laryngologica

authors： Yang Y,Hood LJ,McPherson B

更新日期：2021-01-11 00:00:00

abstract：:In experimental autoimmune labyrinthitis, we found that the guinea pigs sensitized with bovine inner ear antigen (IEAg) developed cellular infiltration within the endolymphatic sac (E. sac). In this study, we investigated the distribution of immune mediated cells within bony vascular channels. The channels, which are ...

journal_title：Acta oto-laryngologica

authors： Yamanobe S,Harris JP,Keithley EM

更新日期：1993-03-01 00:00:00

abstract：:Ionic mechanisms sustaining sensory transduction in crista ampullaris sensory cells have been investigated chiefly by replacing the endolymph with solutions with K+ and Ca++ chelators added. The effects of the modified solutions were evaluated by extracellular and intracellular recordings of both and the presynaptic a...

journal_title：Acta oto-laryngologica

authors： Zucca G,Valli P,Casella C

更新日期：1982-05-01 00:00:00

abstract：:Background: Chronic rhinosinusitis (CRS) is an inflammatory disease of the nose and the paranasal sinuses, often associated with an infection by Staphylococcus aureus (S. aureus). Disturbance in the function of ion channels is regarded as an etiological factor for pathogenesis of CRS. Aims: The study aims to measure t...

journal_title：Acta oto-laryngologica

authors： Saber A,Nakka SS,Hussain R,Hugosson S

更新日期：2019-07-01 00:00:00

abstract：CONCLUSION:The developed software (HITCal) may be a useful tool in the analysis and measurement of the saccadic video head impulse test (vHIT) responses and with the experience obtained during its use the authors suggest that HITCal is an excellent method for enhanced exploration of vHIT outputs. OBJECTIVE:To develop ...

journal_title：Acta oto-laryngologica

authors： Rey-Martinez J,Batuecas-Caletrio A,Matiño E,Perez Fernandez N

更新日期：2015-09-01 00:00:00

abstract：:Macrolides have been used for decades as an important chemotherapeutic agent in the treatment of infectious diseases. In the last 10 years there has also been increasing interest in the interaction between macrolide antibiotics and the immune system. The aim of this review is to focus on the anti-inflammatory action o...

journal_title：Acta oto-laryngologica

authors： Cervin A

更新日期：2001-01-01 00:00:00

abstract：:We established new cell lines from head and neck cancer patients for studies of adhesion molecules and cellular behavior in nine patients with primary or metastatic cancer treated at the Asan Medical Center. Explant cultures of fresh tumor tissue were used to develop new permanent tumor cell lines. Lines were tested f...

journal_title：Acta oto-laryngologica

authors： Kim SY,Chu KC,Lee HR,Lee KS,Carey TE

更新日期：1997-09-01 00:00:00

abstract：:Based on the late results of tympanoplasty on 300 ears and of one-stage mastoidectomy and tympanoplasty on 269 discharging ears, the problems involved in staging tympanoplasty are discussed. The results of one-stage operations were found to be satisfactory 2-10 years after operation. The frequency of recurrent cholest...

journal_title：Acta oto-laryngologica

authors： Tos M

更新日期：1976-09-01 00:00:00

abstract：:Ultrastructural changes of the extrasensory epithelium in the scala media of guinea pig cochleae were observed from 3 to 137 days after perilymphatic perfusion with 20% streptomycin. The degeneration started in the organ of Corti, progressed to the interdental cells and roots of the outer sulcus cells and finally invo...

journal_title：Acta oto-laryngologica

authors： Kaneko Y,Terayama Y,Kawamoto K,Kasajima K,Ise I

更新日期：1978-11-01 00:00:00

abstract：:We studied three-dimensional arrangement of collagen fibers and elastic fibers in the human vocal fold by scanning electron microscopy after digesting cellular elements and collagen fibers with formic acid treatment and cellular elements and elastic fibers with 10% sodium hydroxide. The superficial layer consisted of ...

journal_title：Acta oto-laryngologica

authors： Ishii K,Zhai WG,Akita M,Hirose H

更新日期：1996-09-01 00:00:00

abstract：:Specimens from the epithelium on the lateral wall of the human nose were examined under the electron microscope using a lipid and carbohydrate retaining method. In many of the ciliated epithelial cells and in some of the cells in the mucosal glands we identified multilamellated granules. These structures resembled lam...

journal_title：Acta oto-laryngologica

authors： Svane-Knudsen V,Rasmussen G,Clausen PP

更新日期：1990-03-01 00:00:00

abstract：CONCLUSION:Nasal obstruction, rhinorrhea, and the amount of rhinorrhea that confidently reflect the parasympathetic stimulation can be used to more precisely predict nonspecific nasal hyper-reactivity (NHR). OBJECTIVE:We aimed to identify factors that confidently reflected the presence and the degree of NHR, measured ...

journal_title：Acta oto-laryngologica

authors： Kim YH,Jang TY

更新日期：2012-10-01 00:00:00

abstract：:Detection of immune complexes (ICs) of IgG, IgM, or IgA isotypes in middle ear effusions (MEEs) by the solid-phase anti-C3 ELISA and cytologic analyses of MEEs were done in 245 patients with otitis media with effusion (OME). In 320 ears, the clinical classification was acute, 10.3%; subacute, 16.6%; chronic, 73.1%. In...

journal_title：Acta oto-laryngologica

authors： Yamanaka N,Somekawa Y,Suzuki T,Kataura A

更新日期：1987-11-01 00:00:00

abstract：INTRODUCTION:Bilateral cochlear implants are seen to improve hearing capabilities. OBJECTIVE:To assess the auditory outcome of paediatric bilateral cochlear implant in Universiti Kebangsaan Malaysia. MATERIALS AND METHODS:This was a cross-sectional and descriptive study single centre analysis. Categories of Auditory ...

journal_title：Acta oto-laryngologica

authors： Mohammad Azmi HH,Goh BS,Abdullah A,Umat C

更新日期：2020-10-01 00:00:00

abstract：CONCLUSIONS:We conclude that: (1) among several cues examined, the monaural cue of direct-to-reverberant (D/R) ratio in the ipsilateral ear provides the most information about sound-source distance; (2) interaural level difference (ILD) provides less information about sound-source distance; and (3) a comprehensive theo...

journal_title：Acta oto-laryngologica

authors： Kim DO,Moiseff A,Turner JB,Gull J

更新日期：2008-04-01 00:00:00

abstract：:The efferent cochlear system, composed of both ipsi- and contralateral bundles, runs along with the vestibular nerve and may serve as protection for the inner ear. Sectioning of the vestibular nerve could thus create an experimental model for further in-depth study of such a protective role. A personal surgical approa...

journal_title：Acta oto-laryngologica

authors： Barbara M,Attanasio G,Piccoli F,Filipo R

更新日期：1999-03-01 00:00:00