Abstract:
CONCLUSION:The existence of patients with positive non-sentinel node indicates a risk of misdiagnosis of metastasis in oropharyngeal and oral cancer. OBJECTIVES:We attempted to confirm the usefulness of sentinel lymph node biopsy (SLNB) in oropharyngeal and oral cavity cancer to detect clinically occult metastases. PATIENTS AND METHODS:Twenty-two patients with a mean age of 57 (SD=13) years were studied prospectively. All presented T1-T3 squamous cell carcinoma (SCC) of the oropharynx or oral cavity, and were cN0 on palpation and CT. A preoperative (24 h) lymphoscintigraphy was performed with 99mTc-labelled sulfur colloid injected around the primary tumor. Subsequently, we proceeded with tumor exeresis and detection of SLN following the procedures described in a previous paper. RESULTS:We detected a total of 32 SLNs in 21 of 22 patients. Ipsilateral neck node location was observed in 18 patients and bilateral in 3. We observed 10 patients with true positive SLNs (3 patients had micrometastases), indicating occult metastases. We harvested a total of 454 nodes in our selective neck dissections, 19 of which presented metastatic invasion. We identified four patients with positive non-sentinel nodes.
journal_name
Acta Otolaryngoljournal_title
Acta oto-laryngologicaauthors
Santaolalla F,Sanchez JM,Ereño C,Gonzalez A,Rodriguez ML,Sanchez A,Martinez Adoi
10.1080/00016480801891710subject
Has Abstractpub_date
2008-10-01 00:00:00pages
1159-64issue
10eissn
0001-6489issn
1651-2251pii
791857168journal_volume
128pub_type
杂志文章abstract::Serial Thermal Vestibulometry with the application of increasing caloric stimuli (corresponding to decreasing temperature of water at successive irrigration of the ears) was performed on normal subjects and patients with lesions in the central nervous system involving the statoacoustic subsystem. The normal values and...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016487909137164
更新日期:1979-01-01 00:00:00
abstract:CONCLUSIONS:In computer-assisted analysis of acinic cell cancer (ACC) morphological characteristics of CD34 immunoreactivity were detected. Bigger vessel size, vessel irregularity, and lower intensity of CD34-positive vessel staining may indicate unfavorable prognosis. OBJECTIVES:Salivary gland cancer (SGC) is a morph...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016480601053099
更新日期:2007-08-01 00:00:00
abstract::Organophosphorus compounds in the form of insecticides are in widespread use and have recently attracted considerable interest as environmentally toxic agents. As little is known about the effect of environmental toxins on the tubal function in the ear, we studied the middle ear pressure necessary to force the eustach...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489509139361
更新日期:1995-07-01 00:00:00
abstract:OBJECTIVES:A meta-analysis was conducted to compare oncologic outcomes for patients of T1a glottic carcinoma who were treated with laser surgery (LS) or radiotherapy (RT). METHODS:All related studies published up to October 2016 were acquired by searching PubMed, EMBASE, and Cochrane were conducted by two authors, wit...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章,meta分析
doi:10.1080/00016489.2017.1353706
更新日期:2017-11-01 00:00:00
abstract:CONCLUSION:Our results demonstrate for the first time a potentially enhanced basal secretion of monocyte chemoattractant protein-1 (MCP-1) and interleukin (IL)-17A-stimulated secretion of IL-6 from nasal polyp fibroblasts, enhanced basal secretion of IL-6 from eosinophilic nasal polyp fibroblasts, and a remarkable up-r...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489.2013.796091
更新日期:2013-10-01 00:00:00
abstract::Urokinase-type plasminogen activator (uPA) is important for matrix degradation and motility of cancer cells. The binding of uPA to its cell surface receptor on cancer cells is essential for effective invasion. A soluble form of urokinase receptor (suPAR) has been described in serum and ascites of ovarian cancer patien...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016489950180342
更新日期:1999-01-01 00:00:00
abstract::The submeningeal approach through the middle cranial fossa to the internal auditory meatus and cerebello-pontine angle after cutting the tentorium cerebelli is described. It is in some way similar to that used by Morrison & King. The approach is achieved by drilling the petrous bone to the level of the compact plate o...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016487509121344
更新日期:1975-11-01 00:00:00
abstract::Undifferentiated giant and spindle cell carcinoma is an unusual and high-grade malignant type of cancer of the thyroid. The results of surgical and/or radiotherapeutic treatment have been discouraging. Only a few patients respond to therapy, usually for a short time. Recently, a few reports have been published on the ...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016487709128859
更新日期:1977-03-01 00:00:00
abstract::Topical application of FGF (fibroblast growth factor), a potent mitogen for mesodermal and neuroectodermal cells, was given to promote the healing of tympanic membrane perforations in rats. Calibrated tympanic membrane perforations were performed in 30 rats. At day 0, each rat received 40 microliters of placebo in the...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489109137397
更新日期:1991-01-01 00:00:00
abstract::Background: It has been reported that head-up sleep (HUS) prevents free-floating otoliths from entering canals and that vertical recognition training (VRT) promotes vestibular compensation.Aims/objectives: We would like to assess HUS and VRT for intractable motion-evoked dizziness, including possible benign paroxysmal...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016489.2020.1727566
更新日期:2020-06-01 00:00:00
abstract:OBJECTIVES:The aim of this prospective study was to assess the usefulness of nasal smear eosinophilia compared with a skin sensitivity test for the diagnosis of allergic rhinitis and to determine the degree of correlation between the tests. MATERIAL AND METHODS:Fifty patients with a clinical history suggestive of nasa...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016480310002159
更新日期:2003-12-01 00:00:00
abstract:CONCLUSION:The data suggest that histamine up-regulates MUC2 gene regulation and mucin production in airway epithelial cells through histamine 1 receptor (H1R). Histamine appears to play an important role in the early phase of mucin regulation, which might be effectively blocked by an H1R antagonist. OBJECTIVE:Histami...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489.2012.661075
更新日期:2012-06-01 00:00:00
abstract:CONCLUSION:The possible roles of CD44st, CD44v5 and CD44v6 in the prognosis of head and neck cancer deserve further elucidation and evaluation with long-term patient follow-up. OBJECTIVE:Standard CD44 (CD44st), CD44 variant 5 (CD44v5) and CD44 variant 6 (CD44v6) are expressed in human malignant cells and tissues. The ...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016480510026971
更新日期:2005-04-01 00:00:00
abstract::During the course of a chronic intracochlear electrical stimulation study using charge balanced biphasic current pulses, one animal inadvertently received a short period of direct current (DC) stimulation at a level of approximately 1 microA. Subsequent, the animal was chronically stimulated using a poorly charge bala...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489109138421
更新日期:1991-01-01 00:00:00
abstract::The three-dimensional distribution of the cricoid area was investigated using computer graphics and its histological structure and pathology were studied using whole-organ serial sections. A total of 26 adult human larynges were examined. The findings were as follows: 1. Cricoid areas were located along the superior p...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:
更新日期:2002-12-01 00:00:00
abstract::Fibroblasts in two portions of the vocal fold mucosa, the macula flava (MF) and Reinke's space (RS), were investigated by means of transmission electron microscopy. Five adult and five newborn larynges from autopsy cases were subjected to study. Both in adults and newborns, fibroblasts in the MF tended to be stellate ...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016489950181800
更新日期:1999-03-01 00:00:00
abstract:CONCLUSION:Our results suggest that patients with migraine or tension-type headache have subclinical deviations of the subjective visual vertical, which may be associated with their subjective imbalance. OBJECTIVES:Patients affected by migraine or tension-type headache often complain of unsteadiness. However, they rar...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016480802032785
更新日期:2009-01-01 00:00:00
abstract::By using the microsuction technique, quantitative determination of the chemical mediators in nasal secretions was performed in 40 patients with seasonal allergic rhinitis during the pollen season. The aim of this study was to investigate the actual concentrations of these important mediators in nasal secretions during...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489409126103
更新日期:1994-09-01 00:00:00
abstract::The ultrastructure of the epithelial cells of the endolymphatic duct in the rat is described, following vascular perfusion-fixation of live, anaesthetised and artificially respirated animals. The animals were fixed by means of a pressure feed-back controlled peristaltic pump and an isotonic perfusate-fixative containi...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489409126013
更新日期:1994-01-01 00:00:00
abstract:OBJECTIVE:To develop a large animal model for studies of laryngeal abductor reinnervation. MATERIAL AND METHODS:Six minipigs underwent unilateral anastomosis of the phrenic nerve-abductor branch of the recurrent laryngeal nerve (RLN). Polyhydroxybutyrate (PHB) conduits were used for repair. At each of 30, 60 and 120 d...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016480410022507
更新日期:2004-09-01 00:00:00
abstract:CONCLUSION:A 20 mm hole made backwards from the midpoint of the asterion to the mastoid process is suitable for a retrosigmoid keyhole approach with the aid of an endoscope. The endoscope-assisted retrosigmoid keyhole approach can be considered an effective and safe method for removal of vestibular schwannoma. OBJECTI...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489.2013.817682
更新日期:2013-11-01 00:00:00
abstract:CONCLUSION:We demonstrated an early increase in aquaporin 2 (AQP2) expression in a motor nerve (extratemporal facial nerve, FN) following acute peripheral compression (crush), concomitant to effective development of motor dysfunction (facial palsy). The early increase in AQP2 expression that occurred concomitantly with...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489.2015.1010104
更新日期:2015-07-01 00:00:00
abstract:CONCLUSION:Patients with hiatus hernia can be relieved from H, MSL and MSN by hiatus hernia repair. OBJECTIVE:It has been hypothesized that respiratory symptoms in patients with gastro-oesophageal reflux disease (GORD) may, in some cases, be due to misdirected swallowing as a consequence of defective opening of the up...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016480410017945
更新日期:2005-01-01 00:00:00
abstract::Vestibular microphonics in response to acoustical stimulation were recorded in cochlea-deprived pigeons. Endolymph flow in the semicircular canals alters this response. A caloric stimulus was applied to the horizontal canal or the posterior vertical canal close to the ampulla. To minimize the influence of gravity, the...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016488809097016
更新日期:1988-03-01 00:00:00
abstract:CONCLUSION:The palatal implant method originally designed to reduce snoring can significantly reduce the apnea-hypopnea index (AHI) in some patients with mild to moderate obstructive sleep apnea (OSA) in a single office-based procedure. OBJECTIVE:An initial study designed to evaluate the short-term efficacy and safety...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016480600951392
更新日期:2007-05-01 00:00:00
abstract:CONCLUSION:L-N-Acetylcysteine (L-NAC) significantly reduced reactive oxygen species (ROS) generation and cochlear cell apoptosis after irradiation. The safe and effective use of L-NAC in reducing radiation-induced sensorineural hearing loss (SNHL) should be verified by further in vivo studies. OBJECTIVES:Radiation-ind...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016480701762490
更新日期:2008-04-01 00:00:00
abstract:CONCLUSION:The midline electroneurography (ENoG) method might reflect total facial nerve degeneration. OBJECTIVE:We compared ENoG values in patients with facial palsy using two different methods, the midline method and five electroneurogram recordings, to reveal whether the ENoG value obtained with the midline method ...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489.2012.743680
更新日期:2013-03-01 00:00:00
abstract:CONCLUSIONS:Local administration of MP delivered by the C/GP-MP-hydrogel can improve the recovery of facial nerve following crush injury. The findings suggested that locally injected MP delivered by C/GP-hydrogel might be a promising treatment for facial nerve damage. OBJECTIVES:In this study, the aim is to assess the...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:
更新日期:2015-01-01 00:00:00
abstract::We examined the mucosa of 50 rat middle ears in an experimental model of acute otitis media, in order to obtain information on the mechanisms of polyp formation. The right middle ear of 25 rats was inoculated with type 3 pneumococci, and the left ear served as a control. The animals were killed, the middle ear bulla r...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489509133351
更新日期:1995-01-01 00:00:00
abstract:OBJECTIVE:To investigate the outcome of surgically managed laryngeal carcinoma patients attending an outpatient clinic over a 5-year period. MATERIAL AND METHODS:This was an analytical, retrospective, cross-sectional study. A total of 36 laryngeal carcinoma patients who were managed surgically with or without radiothe...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016480410018070
更新日期:2004-08-01 00:00:00