Fibroblast growth factor improves the healing of experimental tympanic membrane perforations.

abstract：CONCLUSION:An 18-mer peptide derived from the neurotrophic region of prosaposin (PS-pep) prevents hearing loss and cochlear damage due to transient cochlear ischaemia by activating an anti-apoptotic pathway. PS-pep is a potent candidate molecule for alleviating ischaemia-induced hearing loss. OBJECTIVE:PS-pep was inve...

journal_title：Acta oto-laryngologica

authors： Terashita T,Saito S,Nabeka H,Hato N,Wakisaka H,Shimokawa T,Kobayashi N,Gyo K,Matsuda S

更新日期：2013-05-01 00:00:00

abstract：CONCLUSION:No case of death related to surgery in the form of uvulopalatopharyngoplasty, uvulopalatoplasty or nasal surgery for snoring or sleep apnea has been recorded in Sweden among 4876 patients treated between 1997 and 2005. Severe complications of surgery in the peri- and postoperative period, especially in the f...

journal_title：Acta oto-laryngologica

authors： Franklin KA,Haglund B,Axelsson S,Holmlund T,Rehnqvist N,Rosén M

更新日期：2011-03-01 00:00:00

abstract：:Aspartate and alanine aminotransferase (ASAT, ALAT) activities were measured in human post-mortem sera, cerebrospinal fluid (CSF), perilymph and endolymph. Due to heart and/or liver morbidity during a terminal illness, the ASAT and ALAT serum activities were considerably increased as compared with normal and both were...

journal_title：Acta oto-laryngologica

authors： Palva T,Nousiainen R,Raunio V

更新日期：1976-01-01 00:00:00

abstract：:The present morphological study was designed to investigate the expression of HLA class II subregion gene products on human trachea. Frozen sections from the tracheas of 20 cadavers not suffering from ear, nose or throat diseases were studied immunohistochemically using monoclonal antibodies which recognize monomorphi...

journal_title：Acta oto-laryngologica

authors： Bujia J,Wilmes E,Hammer C,Kastenbauer E

更新日期：1990-07-01 00:00:00

abstract：:The distribution of vascular endothelial growth factor (VEGF), one of the most important angiogenic factors, and microvessel density (MVD) were assessed in laryngeal carcinomas by means of immunohistochemistry. Correlation of VEGF with MVD and clinical parameters (T stage, N stage, histological grading, survival, recu...

journal_title：Acta oto-laryngologica

authors： Neuchrist C,Quint C,Pammer A,Burian M

更新日期：1999-01-01 00:00:00

abstract：:The objective of this study was to examine the outcome of unilateral stapes surgery in one patient group with bilateral hearing loss and one group with unilateral hearing loss. The patients' own estimations of improvement in hearing ability and the occurrence of other ear-related symptoms were examined retrospectively...

journal_title：Acta oto-laryngologica

authors： Lundman L,Mendel L,Bagger-Sjöbäck D,Rosenhall U

更新日期：1999-01-01 00:00:00

abstract：:The maculae sacculi and utriculi of the chinchilla vestibular labyrinth have been studied by freeze-fracture method. In the replicas extensive zonulae occludentes have been found between sensory and supporting cells at the endolymphatic surface. Gap junctions are located between the supporting cells. Some intramembran...

journal_title：Acta oto-laryngologica

authors： Laciano L,Franke K,Iurato S,Reale E

更新日期：1977-01-01 00:00:00

abstract：:During the development of the mammalian inner ear, the number of hair cells produced is highly regulated and remains constant throughout life. The mechanism underlying this regulation is beginning to be understood although many aspects still remain obscure. When late embryonic or early postnatal rat organs of Corti we...

journal_title：Acta oto-laryngologica

authors： Lefebvr PP,Malgrange B,Thiry M,Breuskin I,Van De Water TR,Moonen G

更新日期：2001-01-01 00:00:00

abstract：:The expression of the intermediate filament subclasses cytokeratins (CKs), vimentin, and neurofilament triplet proteins (NFs) was analysed in the embryonic inner ear of the CBA/CBA mouse, in vivo and in vitro, using well-defined monoclonal antibodies. Some of the cultured inner ears were exposed to 1-10 micrograms/ml ...

journal_title：Acta oto-laryngologica

authors： Berggren D,Anniko M,Thornell LE,Ramaekers FC,Virtanen I

更新日期：1990-01-01 00:00:00

abstract：:Using primary cultures of marginal cells of stria vascularis from guinea pig and gerbil, ionic channels located on the luminal membrane were investigated by means of patch clamp technique. Recordings were performed in cell-attached and inside-out configurations. In cell-attached configuration, single channel activity ...

journal_title：Acta oto-laryngologica

authors： Liu DS,Achouche J,Wu AH,Trotier D,Tran Ba Huy P

更新日期：1991-01-01 00:00:00

abstract：CONCLUSIONS:The most likely cause of lesions with an absence of the long process of the incus was congenital origin because many cases were associated with the stapedial anomaly. However, the possibility of a potential inflammation of this lesion could not be completely excluded, especially in cases with only an absenc...

journal_title：Acta oto-laryngologica

authors： Park K,Choung YH,Shin YR,Hong SP

更新日期：2007-08-01 00:00:00

abstract：CONCLUSIONS:We describe a Japanese family with high-frequency sensorineural hearing loss (SNHL) harboring a c.211delC mutation in the KCNQ4 gene. Families showing progressive high-frequency SNHL should be investigated for mutations in the KCNQ4 gene. OBJECTIVE:To determine the responsible deafness gene in a Japanese f...

journal_title：Acta oto-laryngologica

authors： Ishikawa K,Naito T,Nishio SY,Iwasa Y,Nakamura K,Usami S,Ichimura K

更新日期：2014-06-01 00:00:00

abstract：:Most epidemiological surveys concerning populations exposed to occupational noise or random populations have shown that the left ear is slightly but significantly poorer than the right ear, especially at frequencies most susceptible to noise damage. To experimentally study the possible left-right asymmetry in response...

journal_title：Acta oto-laryngologica

authors： Pirilä T

更新日期：1991-01-01 00:00:00

abstract：:Juvenile nasopharyngeal angiofibroma is a disease afflicting mainly adolescent males. The lesion is benign but characterized by local aggressive growth. In advanced cases the tumour may extend intracranially. In this study 18 cases of juvenile nasopharyngeal angiofibroma were investigated. Tumour extension was assesse...

journal_title：Acta oto-laryngologica

authors： Jacobsson M,Petruson B,Svendsen P,Berthelsen B

更新日期：1988-01-01 00:00:00

abstract：PURPOSE:To analyze the outcomes following re-irradiation for local recurrence of rare head and neck tumors. MATERIAL AND METHODS:We retrospectively analyzed 11 patients who had received intensity-modulated radiation therapy (IMRT) for recurrent tumors in the head and neck except for laryngopharynx. RESULTS:Primary tu...

journal_title：Acta oto-laryngologica

authors： Doi H,Uemoto K,Masai N,Tatsumi D,Shiomi H,Oh RJ

更新日期：2018-08-01 00:00:00

abstract：CONCLUSIONS:Osteomas of the incus were found in surprisingly high numbers in ancient and modern populations. The coexistence of osteoma formation and unique vascularization on the medial surface of the incus alludes to a relationship between the two findings. OBJECTIVE:Osteomas involving the middle ear ossicles are ra...

journal_title：Acta oto-laryngologica

authors： Arensburg B,Belkin V,Wolf M

更新日期：2005-11-01 00:00:00

abstract：CONCLUSIONS:Patients with sudden hearing loss and dizziness after barotrauma should be suspected of barotraumatic perilymph fistula (PLF). Early surgical repair of PLF showed better hearing outcomes. Therefore, diagnostic criteria should help surgical indications of barotraumatic PLF. OBJECTIVES:The aim of this study ...

journal_title：Acta oto-laryngologica

authors： Choi JE,Moon IJ,Kim H,Lee K,Cho YS,Chung WH

更新日期：2017-01-01 00:00:00

abstract：CONCLUSION:The clinical presentation and outcome of post-traumatic benign paroxysmal positional vertigo (t-BPPV) are different from those idiopathic BPPV (i-BPPV). It appears that t-BPPV is more difficult to treat than i-BPPV. OBJECTIVE:To identify the clinical presentation and outcome of t-BPPV. METHODS:We reviewed ...

journal_title：Acta oto-laryngologica

authors： Liu H

更新日期：2012-08-01 00:00:00

abstract：:Nl action potentials, elicited by low-level, 4.0-kHz filtered clicks, were recorded from the ear canals of normal-hearing adults. Responses were recorded at two sensation levels in the presence and absence of a pure tone delivered to the contralateral ear. Waveforms were analysed for changes in amplitude and latency. ...

journal_title：Acta oto-laryngologica

authors： Folsom RC,Owsley RM

更新日期：1987-05-01 00:00:00

abstract：:An in vivo method for the study of mucociliary activity in the human trachea and bronchi is presented. The method is based on a two-way fibre-optic system whereby reflections of light emitted by one glass-fibre and reflected by the cilia are picked up by a second glass fibre and transmitted to a recording unit. The gl...

journal_title：Acta oto-laryngologica

authors： Huberman D

更新日期：1993-09-01 00:00:00

abstract：CONCLUSION:Extensive bone erosion correlated with a worse prognosis of the squamous cell carcinoma (SCC) of the temporal bone but extensive soft tissue involvement did not correlate with prognosis in this study. Resectability of the tumor seems to be major prognostic factor of temporal bone SCC. OBJECTIVE:Prognostic f...

journal_title：Acta oto-laryngologica

authors： Ito M,Hatano M,Yoshizaki T

更新日期：2009-11-01 00:00:00

abstract：UNLABELLED:Abstract Conclusions: In survival analysis, the combined Charlson comorbidity index (CCI) can be considered as a prognostic factor independent of the tumor node metastasis (TNM) classification, tumor stage, and tumor location. Severe comorbidity was the factor that had the greatest impact on prognosis in cas...

journal_title：Acta oto-laryngologica

authors： Gimeno-Hernández J,Iglesias-Moreno MC,Gómez-Serrano M,Carricondo F,Gil-Loyzaga P,Poch-Broto J

更新日期：2011-08-01 00:00:00

abstract：OBJECTIVE:To develop a large animal model for studies of laryngeal abductor reinnervation. MATERIAL AND METHODS:Six minipigs underwent unilateral anastomosis of the phrenic nerve-abductor branch of the recurrent laryngeal nerve (RLN). Polyhydroxybutyrate (PHB) conduits were used for repair. At each of 30, 60 and 120 d...

journal_title：Acta oto-laryngologica

authors： Birchall M,Idowu B,Murison P,Jones A,Burt R,Ayling S,Stokes C,Pope L,Terenghi G

更新日期：2004-09-01 00:00:00

abstract：:Thirty-two patients affected by idiopathic benign paroxysmal positional vertigo (BPPV) of the posterior semicircular canal were studied before, 3 days and I month after a resolutive Semont manoeuvre by means of dynamic posturography. The overall postural control in BPPV patients was shown to be impaired, as demonstrat...

journal_title：Acta oto-laryngologica

authors： Di Girolamo S,Paludetti G,Briglia G,Cosenza A,Santarelli R,Di Nardo W

更新日期：1998-06-01 00:00:00

abstract：:Overexpression of epidermal growth factor receptor (EGF-R) is a common characteristic of epidermoid tumors and its expression in head and neck squamous cell carcinoma biopsies and cell lines has been reported previously by several authors. With the aim to provide more structural and functional details about the protei...

journal_title：Acta oto-laryngologica

authors： Bujía J,Wustrow TP

更新日期：1993-11-01 00:00:00

abstract：:This is a study of the effects of repeated angular acceleration on the activity of vestibular nuclei units in anesthetized and in conscious cats. The experimental animals were subjected to trains of repeated and consecutive constant acceleration-deceleration ramps (4-8 degrees/sec2). In a few cases nystagmus was recor...

journal_title：Acta oto-laryngologica

authors： Kileny P,Ryu JH,McCabe BF,Abbas PJ

更新日期：1980-09-01 00:00:00

abstract：:The purpose of this study was to show the early stages of polyp formation, as part of our studies on the pathogenesis of nasal polyps. Two and 4 weeks after experimental tubal occlusion in 18 Wistar rats, 13 showed signs of bacterial infection, respective acute otitis media. In the majority of these rats polypouslike ...

journal_title：Acta oto-laryngologica

authors： Larsen PL,Tos M

更新日期：1991-01-01 00:00:00

abstract：:An X-ray energy dispersive analysis was performed on the mature serial sectioned freeze-dried mammalian labyrinth (CBA/CBA mouse). The elemental distribution in the endolymphatic and perilymphatic spaces revealed similar results as have been reported in the literature when withdrawing fluid for microanalysis. The cupu...

journal_title：Acta oto-laryngologica

authors： Anniko M,Wroblewski R

更新日期：1980-11-01 00:00:00

abstract：:The DBA/2 strain of mice have genetically induced vestibular dysfunction that presents grossly at an early age as circling behavior and abnormal righting reflexes. The vestibular morphology of this strain has not previously been examined. DBA/2 mice of different ages that showed circling behavior were sacrificed and t...

journal_title：Acta oto-laryngologica

authors： Bloom D,Hultcrantz M

更新日期：1994-07-01 00:00:00

abstract：CONCLUSION:The curative effect in the group where facial-facial anastomosis (FFA) was delayed for 7 days was similar to that in the immediate FFA group and had a better repair within 60 days. OBJECTIVE:Due to the uncertainty about optimal timing of delayed facial nerve repair, we designed an experimental study in guin...

journal_title：Acta oto-laryngologica

authors： Hu J,Zhou L,Ma Z

更新日期：2013-07-01 00:00:00