Abstract:
:An in vivo method for the study of mucociliary activity in the human trachea and bronchi is presented. The method is based on a two-way fibre-optic system whereby reflections of light emitted by one glass-fibre and reflected by the cilia are picked up by a second glass fibre and transmitted to a recording unit. The glass fibre system is designed to be used in conjunction with a regular fibre bronchoscope, and is convenient for routine use in daily clinical work. As reference material, 15 subjects aged 23-73 years without evidence of disease were examined in their right upper bronchus. The average cilial beat frequency was found to be 12.0 +/- 1.0 (SD) waves per second.
journal_name
Acta Otolaryngoljournal_title
Acta oto-laryngologicaauthors
Huberman Ddoi
10.3109/00016489309135885subject
Has Abstractpub_date
1993-09-01 00:00:00pages
683-6issue
5eissn
0001-6489issn
1651-2251journal_volume
113pub_type
杂志文章abstract:CONCLUSION:The visual outcomes of endoscopic treatment of optic neuropathy are favorable. However, no specific prognostic factor was associated with good outcome. OBJECTIVE:To investigate visual outcomes of patients with optic neuropathy caused by paranasal mucocele or sinusitis. METHODS:The clinical course in 38 pat...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489.2011.557837
更新日期:2011-08-01 00:00:00
abstract:CONCLUSION:Changes in the metabolism of arachidonic acid (AA) might be part of a noise-induced compensatory mechanism with regional specificity. OBJECTIVES:The released imbalance of prostaglandins and leukotrienes, both AA metabolites, might result in altered blood flow regulation in the inner ear and probably contrib...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016480903168066
更新日期:2010-03-01 00:00:00
abstract::Background: Betahistine is used worldwide to treat patients with Menière's disease. However, despite it being used for decades, diverging opinions on the effect of betahistine on Menière's symptomatology still exist.Aims: The objective of this systematic review was to provide an overview and rate the certainty of the ...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016489.2020.1777326
更新日期:2020-10-01 00:00:00
abstract::Morphology of the tympanic membrane (TM) and external auditory canal (EAC) was studied in healthy, intact rat ears. TM-perforated ears (3 days after making the perforation) and TM-perforation-healed ears (14, 28 and 42 days after making the perforation). In intact ears, the epidermis in the annular region of the EAC d...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489609137939
更新日期:1996-11-01 00:00:00
abstract::The ultrastructural pattern of the acoustic nerve Schwannoma was studied on surgically excised tumours and on explants cultured in vitro. The typical neoplastic cell is elongated, spindle-shaped, coated with basement membrane and numerous protruding cellular processes. Cells demonstrating numerous microfilaments are a...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016488509108909
更新日期:1985-03-01 00:00:00
abstract::In experiments on 11 dogs, the authors attempted to develop a method for avoiding serious complications following simultaneous bilateral radical neck dissection. Both internal jugular veins were resected; one vein was reconstructed with the autologous v. femoralis. Blood flow in the reconstructed vein was normal in th...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016488409132914
更新日期:1984-05-01 00:00:00
abstract::By using the microsuction technique, quantitative determination of the chemical mediators in nasal secretions was performed in 40 patients with seasonal allergic rhinitis during the pollen season. The aim of this study was to investigate the actual concentrations of these important mediators in nasal secretions during...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489409126103
更新日期:1994-09-01 00:00:00
abstract:CONCLUSIONS:The intra-tumoral cytokines IL-6, hepatocyte growth factor (HGF) and tumour necrosis factor-a (TNF-a) stimulate oral cancer cells to enhanced secretion of matrix metalloproteinase (MMP)-1 and -9. These results contribute to an understanding of the extracellular events necessary for tumour progression. OBJE...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016480510027484
更新日期:2005-07-01 00:00:00
abstract:OBJECTIVE:To investigate the hearing prognosis of idiopathic sudden sensorineural hearing loss (SSNHL) treated with different initial therapies. METHODS:Subjects consisted of patients diagnosed with idiopathic SSNHL within 7 days from onset and showing severe hearing loss (≥60 dB), who were registered in a Japanese mu...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章,多中心研究
doi:10.1080/00016489.2017.1296970
更新日期:2017-01-01 00:00:00
abstract::We have recorded auditory evoked potentials, of both neurogenic and myogenic origin, in cats having neonatal high frequency cochlear hearing loss. Using frequency specific stimuli (tone pips) and by measuring responses near to threshold, we have probed tonotopic (or cochleotopic) representation within the brainstem-mi...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489309135763
更新日期:1993-01-01 00:00:00
abstract:CONCLUSION:Cochlear implantation is a safe procedure in experienced hands, as the rate of severe complications is below 2%. Complications differ between children and adults, and transient disequilibrium/vertigo is the most common complication, followed by wound infection, haematoma/oedema and transient chorda tympani s...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016480903358261
更新日期:2010-05-01 00:00:00
abstract:OBJECTIVE:Setting the optimal rate of stimulation for individual cochlear implant recipients is critical to the successful functional outcome of cochlear implantation. In the absence of an objective methodology, cochlear implants are currently fitted by means of a time-consuming (and therefore expensive) trial-and-erro...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016480310002168
更新日期:2004-08-01 00:00:00
abstract:CONCLUSION:Telephone usage is a difficult challenge for cochlear implanted patients. A significant number of cochlear implanted patients are able to carry on a land-line or mobile telephone conversation. The telephone model may be a critical factor for telephone performance. OBJECTIVES:The goals of this study were to ...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016480500469552
更新日期:2006-07-01 00:00:00
abstract::Immunological mechanisms are thought to play an important role in the pathogenesis of some cochleo-vestibular diseases. This study attempts to present further evidence of autoantibodies reactive against guinea pig inner ear proteins found in patients with autoimmune inner ear diseases (AIED) and specifically identifie...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/000164801300006236
更新日期:2001-01-01 00:00:00
abstract::Synthesis of prostaglandins (PGs) was characterized in the lateral wall (LW) of guinea-pig cochlea. Basal synthesis at 37 degrees C was about 480 pg/LW (12.8 ng X mg-1 protein) for PGI2 and 85 pg/LW (2.3 ng X mg-1 protein) for PGE2, levelling out after 10 min of incubation. Incubation with arachidonic acid (10(-5) M) ...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:
更新日期:1987-05-01 00:00:00
abstract::Luetic hydrops can occur in both congenital and acquired lues and otologic manifestations may be indistinguishable from Meniere's disease. Eight endolymphatic sac decompression procedures were performed on 6 patients with refractory luetic vertigo. Of those, 3 had congenital and 3 acquired lues. All cases had received...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016488009127172
更新日期:1980-05-01 00:00:00
abstract::Middle ear lesions were produced in chinchillas by introducing fascia, Gelfoam, silastic or a combination of these materials into the labyrinthine and mastoid bullae. After 1-2 months, conventional 226 Hz and multifrequency tympanometry (MFT) were performed and the animals were sacrificed for histopathological analysi...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016489850154937
更新日期:1998-03-01 00:00:00
abstract::A questionnaire was devised to quantify and measure four categories: the behavioral characteristics of Type A, self-restraint and escape; the causes of anxiety; means of relaxation; and symptoms incidental to anxiety. Questionnaire analysis was performed in patients (n = 60) with Meniere's disease and in a control pop...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/000164801300043721
更新日期:2001-01-01 00:00:00
abstract::We have developed a new technique for analyzing the rotation vector of eye movement in three dimensions with an infrared CCD camera based on the following four assumptions; i) the eye rotates on a point; ii) the pupil edge is a circle; iii) the distance from the center of eye rotation to pupil circle remains unchanged...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016489950181882
更新日期:1999-01-01 00:00:00
abstract::Several reports have indicated that some cochlear implant patients experience a reduction in their tinnitus while listening to noise or speech. In the present study, two patients reporting bilateral tinnitus were selected from a group of adults with the Nucleus cochlear implant. They rated their tinnitus loudness and ...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489309135811
更新日期:1993-05-01 00:00:00
abstract::A family with early-onset vestibulopathy is presented. The 34-year-old father had experienced brief attacks of vertigo and currently suffers from unsteadiness and oscillopsia during head movements. His two young sons also experience brief attacks of spontaneous vertigo. In vestibular testing all three subjects showed ...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016480310002500
更新日期:2003-08-01 00:00:00
abstract::Histological measures of cochlear vasculature and blood flow were examined in 20 guinea pigs. Sixteen were exposed to octave band noise at 120 dB SPL for 30 min and then permitted to survive after the exposure for 6 h, 18 h, 48 h, or 4 weeks (N = 4 in each group). Control animals were exposed to the laboratory and app...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016488509108582
更新日期:1985-07-01 00:00:00
abstract::Microsurgery of the facial nerve has resulted in a great progress by regaining, thanks to its various techniques, not only the voluntary movements of the face but in addition also the emotional expressive motility. It has become evident, however, that one disadvantage is always unavoidable even in the most subtle reco...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016488109138533
更新日期:1981-05-01 00:00:00
abstract:HYPOTHESIS:To examine the cellular events following induced superficial lesions of the human tympanic membrane (TM). Such information could lead to enhanced appreciation of repair mechanisms and novel strategies to restore TM perforations. BACKGROUND:Persistent perforation of the TM in chronic otitis media is a major ...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016489.2017.1321139
更新日期:2017-09-01 00:00:00
abstract:CONCLUSIONS:Surgery for oral or oropharyngeal cancer with free-flap reconstruction is associated with moderate but persistent functional and quality of life (QoL) problems. Patient age, tumor stage, tumor site, and radiotherapy were the main predictors of functional outcome. OBJECTIVES:To evaluate long-term functional...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489.2014.913809
更新日期:2014-10-01 00:00:00
abstract::Topical application of FGF (fibroblast growth factor), a potent mitogen for mesodermal and neuroectodermal cells, was given to promote the healing of tympanic membrane perforations in rats. Calibrated tympanic membrane perforations were performed in 30 rats. At day 0, each rat received 40 microliters of placebo in the...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489109137397
更新日期:1991-01-01 00:00:00
abstract:CONCLUSIONS:The microarray analysis identified 39 genes up- or down-regulated by dexamethasone in the cultured tissue of mice cochlea. Of the eight genes most highly affected, several are suggested to have protective effects in the traumatized inner ear (Fkbp5, Glucocorticoid-induced leucine zipper (Gilz), glutathione ...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489.2010.498836
更新日期:2010-12-01 00:00:00
abstract::Six profoundly deaf patients were studied with mapping evoked potentials (MEP) using an acoustic signal passed through the vibrotactile prosthesis. This stimulus produced an activation of the central sulcus brain cortex. When the proSthesis was placed in the presenternal area it showed N1 P1 potentials with higher vol...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489709117771
更新日期:1997-03-01 00:00:00
abstract:CONCLUSION:The psychometric characteristics of Standard-Chinese lexical neighborhood test (LNT) confirmed the lexical effects of the four word categories. The established normative baseline can be used in evaluating the word-recognition performance of the hearing-impaired listeners. OBJECTIVES:The purpose of the prese...
journal_title:Acta oto-laryngologica
pub_type: 临床试验,杂志文章
doi:10.3109/00016489.2013.840923
更新日期:2014-01-01 00:00:00
abstract::Cisplatin and gentamicin are two ototoxicants that are supposed to be transported by the paracellar route, i.e. via cellular junctions, to the perilymphatic compartment. This study was initiated to test the hypothesis that susceptive variation of individuals to ototoxic drugs may be explained by variability in transpo...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/000164800750061624
更新日期:2000-10-01 00:00:00