Effects of mechanical trauma to the human tympanic membrane: an experimental study using transmission electron microscopy.

abstract：:It has already been reported that anaphylatoxin (AT) is closely related to inner ear lesions. In this study the pathology of inner ear damage caused by AT was investigated in Hartley strain and C4 deficient guinea pigs (C4D-GP). Although the biological activity of C3a and C5a is strong, it is of short duration, and th...

journal_title：Acta oto-laryngologica

authors： Harada T,Sano M,Matsunaga T

更新日期：1992-01-01 00:00:00

abstract：:Paclitaxel (Taxol) is an antimicrotubular agent which blocks the cells in the G2/M phase of the cell cycle. Because of this mechanism it is presumed that this drug could function as a radiation sensitizer. The cytotoxic and genotoxic effects of paclitaxel and a combination of paclitaxel and radiation were studied in t...

journal_title：Acta oto-laryngologica

authors： Preisler VK,Stopper H,Schindler D,Friedl R,Pfreundner L,Hoppe F,Hagen R

更新日期：1998-07-01 00:00:00

abstract：BACKGROUND:The most crucial clinical problem of Eosinophilic Otitis Media (EOM) is sensorineural hearing loss. A previous report revealed that repeated antigen stimulation of middle ear causes eosinophilic inflammation not only in the middle ear but also in the inner ear. OBJECTIVE:The purpose of the present study was...

journal_title：Acta oto-laryngologica

authors： Kudo N,Matsubara A,Nishizawa H,Miura T

更新日期：2017-05-01 00:00:00

abstract：CONCLUSION:Videomicroscopy with subpixel analysis is an excellent system for quantification of outer hair cell (OHC) movements. The resolution of a few nanometers is accurate enough to show induced differences of electromotility. OBJECTIVE:Electromotility of OHCs is a voltage-dependent process resulting from a membran...

journal_title：Acta oto-laryngologica

authors： Canis M,Ortner M,Olzowy B,Jahn K,Strupp M,Hemmert W,Berghaus A,Suckfuell M

更新日期：2008-03-01 00:00:00

abstract：CONCLUSION:Given the phonetic balancing across lists and the validation with spectrally degraded speech, the present Mandarin disyllable recognition test (DRT) materials may be useful for assessing speech performance of Mandarin-speaking cochlear implant (CI) users. If combined with the previously developed sentence ma...

journal_title：Acta oto-laryngologica

authors： Zhu M,Wang X,Fu QJ

更新日期：2012-08-01 00:00:00

abstract：:The perilymphatic space of the guinea pig was perfused in situ with artificial perilymph containing [32P] orthophosphate and 3H-glycerol while cochlear microphonic potentials (CM) were monitored. The perfusion of 10 mM gentamicin suppressed CM by 62% within 30 min. 32P-incorporation into phosphatidylinositol bisphosph...

journal_title：Acta oto-laryngologica

authors： Tachibana M,Anniko M,Schacht J

更新日期：1983-07-01 00:00:00

abstract：:Fifteen normal speakers (7 women and 8 men), ranging in age from 21 to 35 years, were examined consecutively with rigid telescopy and flexible fiberscopy during sustained phonation at 3 loudness levels. The endoscopes were connected to a stroboscope and video equipment. The purpose was to investigate whether the two l...

journal_title：Acta oto-laryngologica

authors： Södersten M,Lindestad PA

更新日期：1992-01-01 00:00:00

abstract：CONCLUSIONS:The presented results add further support to the observation that laser microsurgery is the preferential surgical treatment for recurrent respiratory papillomatosis (RRP). A meticulous follow-up for early recognition of local recurrence and malignant transformation is recommended. OBJECTIVES:Endoscopic mic...

journal_title：Acta oto-laryngologica

authors： Preuss SF,Klussmann JP,Jungehulsing M,Eckel HE,Guntinas-Lichius O,Damm M

更新日期：2007-11-01 00:00:00

abstract：:This study was designed to investigate morphological changes in the tympanic membrane (TM) associated with cholesteatoma formation in experimental animals following application of propylene glycol to the middle ear. A 50% solution of propylene glycol was applied bilaterally to the middle ear cavities of 30 young-adult...

journal_title：Acta oto-laryngologica

authors： Masaki M,Wright CG,Lee DH,Meyerhoff WL

更新日期：1989-07-01 00:00:00

abstract：CONCLUSIONS:The most likely cause of lesions with an absence of the long process of the incus was congenital origin because many cases were associated with the stapedial anomaly. However, the possibility of a potential inflammation of this lesion could not be completely excluded, especially in cases with only an absenc...

journal_title：Acta oto-laryngologica

authors： Park K,Choung YH,Shin YR,Hong SP

更新日期：2007-08-01 00:00:00

abstract：:A time-sequence study was made of the early ultrastructural changes of the stria vascularis and Reissner's membrane in the guinea pig after obliteration of the endolymphatic sac and duct. Pathological alterations of both the stria vascularis and Reissner's membrane were found to start in the apex of the cochlea. The m...

journal_title：Acta oto-laryngologica

authors： Albers FW,de Groot JC,Veldman JE,Huizing EH

更新日期：1987-09-01 00:00:00

abstract：:Gaze functions under high-frequency head oscillations with large amplitudes were investigated in 12 normal subjects. Oscillation amplitude decreased as the frequency increased (31 degrees at 2 Hz to 11 degrees at 5 Hz on average). Maximum head velocity and acceleration were 170-200 degrees/s and 2,500-5,000 degrees/s2...

journal_title：Acta oto-laryngologica

authors： Takahashi M,Akiyama I,Tsujita N

更新日期：1989-03-01 00:00:00

abstract：CONCLUSION:The prognosis of the clinically positive neck in temporal bone squamous cell carcinoma is bad and failures never occur in the neck but at the site of the primary. A clinically positive neck at presentation is a sign of aggressiveness of the primary and, in such cases, therapeutic neck dissection is to be per...

journal_title：Acta oto-laryngologica

authors： Zanoletti E,Danesi G

更新日期：2010-08-01 00:00:00

abstract：:Material for electron microscopy study was obtained from a patient previously suffering from Meniere's disease and treated by ultrasound. It consisted of parts of the membranous labyrinth as well as the vestibular ganglion. The neuro-epithelium of the macula showed degenerative changes and there was marked vacuolation...

journal_title：Acta oto-laryngologica

authors： Colman BH,Friedmann I,Wright JL

更新日期：1975-03-01 00:00:00

abstract：:The sensory and secretory epithelia may become morphologically changed following the exposure to mercury chloride. The earliest and most sever change in the sensory epithelium appeared in the apical part of the cochlea, while the basal coils were only seldom damaged (cytocochleogram studies). Acute intoxication mostly...

journal_title：Acta oto-laryngologica

authors： Anniko M,Sarkady L

更新日期：1978-03-01 00:00:00

abstract：:In 82 patients with acute tonsillitis studied, beta-hemolytic group A streptococci were isolated from 30 (37%), and group C or G streptococci from 12 (15%). In the 40 patients with non-streptococcal tonsillitis there was a significantly higher isolation rate of pneumococci, H. influenzae and/or B. catarrhalis, as comp...

journal_title：Acta oto-laryngologica

authors： Stjernquist-Desatnik A,Prellner K,Christensen P

更新日期：1987-09-01 00:00:00

abstract：:Nasal polyps is a chronic inflammatory disease of the upper airway characterized by structural abnormalities including stromal fibrosis. Fibroblasts are a rich source of cytokines and inflammatory mediators and are thought to play an important role in the development of fibrosis. In addition, there is considerable evi...

journal_title：Acta oto-laryngologica

authors： Nonaka M,Pawankar R,Saji F,Yagi T

更新日期：1999-01-01 00:00:00

abstract：:45CaCl2 was injected into gerbils in single or multiple doses, and the resulting radioactivity in serum, otoconial CaCO3, bone samples, and selected labyrinthine epithelium was determined by liquid scintillation spectrometry. Incorporation into both utricular and saccular otoconia occurred at the rate of 0.06-0.07 nmo...

journal_title：Acta oto-laryngologica

authors： Preston RE,Johnsson LG,Hill JH,Schacht J

更新日期：1975-09-01 00:00:00

abstract：:A platinum-iridium electrode with a Teflon cover tube was chronically implanted through the round window into the scala tympani of the guinea pig. Animals were sacrificed at 30 to 40 weeks after electrode implantation, and the cochleae were observed by scanning electron microscopy or with light microscopy. The results...

journal_title：Acta oto-laryngologica

authors： Gyo K

更新日期：1988-03-01 00:00:00

abstract：CONCLUSIONS:Concurrent chemoradiotherapy with carboplatin and uracil-f tegafur (UFT) seems to be a promising and appropriate regimen for patients with poor performance status (PS) with locally advanced squamous cell carcinoma of the head and neck (SCCHN). OBJECTIVE:We designed a regimen based on divided low-dose admin...

journal_title：Acta oto-laryngologica

authors： Katori H,Tsukuda M,Taguchi T

更新日期：2007-10-01 00:00:00

abstract：CONCLUSION:The clinical presentation and outcome of post-traumatic benign paroxysmal positional vertigo (t-BPPV) are different from those idiopathic BPPV (i-BPPV). It appears that t-BPPV is more difficult to treat than i-BPPV. OBJECTIVE:To identify the clinical presentation and outcome of t-BPPV. METHODS:We reviewed ...

journal_title：Acta oto-laryngologica

authors： Liu H

更新日期：2012-08-01 00:00:00

abstract：:Upper airway symptoms are common, but there is little information available on clinical findings in relation to indoor air pollution. This pilot study was conducted to test whether increased levels of indoor air pollutants in schools may correlate to a swelling of the nasal mucosa. The assumption was made that the deg...

journal_title：Acta oto-laryngologica

authors： Wålinder R,Norbäck D,Wieslander G,Smedje G,Erwall C

更新日期：1997-09-01 00:00:00

abstract：CONCLUSION:The results suggest that the beneficial effect of astragaloside IV on impulse noise-induced hearing loss may be due to its ability to inhibit reactive oxygen species (ROS) and prevent apoptosis. OBJECTIVE:Astragaloside IV is the major active constituent of Astragalus membranaceus, which has been widely used...

journal_title：Acta oto-laryngologica

authors： Xiong M,He Q,Lai H,Wang J

更新日期：2012-05-01 00:00:00

abstract：:The facial nerve of the albino rat was compressed by inserting a thin nylon thread in the facial canal. After a survival period of 1-60 days, the animal was perfused with Ringer's solution followed by a 2% periodate-lysine-paraformaldehyde fixative. Frozen sections from the brain stem containing the facial motor nucle...

journal_title：Acta oto-laryngologica

authors： Ruan RS,Leong SK,Yeoh KH

更新日期：1994-05-01 00:00:00

abstract：CONCLUSION:This study demonstrated that five Cx26 mutations (R32H, S199F, 572delT, 631-632delGT, and Y155X) affect gap junction (GJ) functions by causing impaired membrane targeting and aberrant cellular localization, and one mutation (R165W) leads to a constriction of the channel pore with no dye coupling. OBJECTIVE:...

journal_title：Acta oto-laryngologica

authors： Xiao Z,Yang Z,Liu X,Xie D

更新日期：2011-01-01 00:00:00

abstract：:We investigated the postoperative conditions of ears and the hearing acuity of patients who underwent posterior canal wall reconstruction tympanoplasty for operated ears with open mastoid. The study included 118 ears of 105 patients (57 males, 48 females; age range 5-75 years) and the patients were followed for > 1 ye...

journal_title：Acta oto-laryngologica

authors： Sasaki Y,Iino Y,Suzuki J

更新日期：2002-04-01 00:00:00

abstract：CONCLUSION:The narrowing pattern of the upper airway in obstructive sleep apnea patients may be different in sleep as compared with awake. Three different types of obstruction were observed in these subjects during drug-induced sleep. The different obstruction pattern during drug-induced sleep suggests that different s...

journal_title：Acta oto-laryngologica

authors： Chuang LP,Chen NH,Li HY,Lin SW,Chou YT,Wang CJ,Liao YF,Tsai YH

更新日期：2009-12-01 00:00:00

abstract：BACKGROUND:Posterior tympanotomy (PT) is an important step in cochlear implant (CI) surgery, as it is the main access to the round window. Some CI candidates, especially children, may have concomitant otitis media with effusion (OME) which may result in technical issues during PT. There is still a debate whether to wai...

journal_title：Acta oto-laryngologica

authors： Elzayat S,Nada I,El Sherif H,Mahrous A

更新日期：2021-01-01 00:00:00

abstract：CONCLUSION:The technology of stimulation rates between 1500 and 5000 pulses per second per channel (pps/ch) brings a benefit for all users. However, the fastest possible rate does not necessarily lead to best hearing performance in each individual subject. Individual optimization of stimulation rate is recommended. OB...

journal_title：Acta oto-laryngologica

authors： Buechner A,Frohne-Büchner C,Gaertner L,Stoever T,Battmer RD,Lenarz T

更新日期：2010-01-01 00:00:00

abstract：:Ultrastructural changes of the extrasensory epithelium in the scala media of guinea pig cochleae were observed from 3 to 137 days after perilymphatic perfusion with 20% streptomycin. The degeneration started in the organ of Corti, progressed to the interdental cells and roots of the outer sulcus cells and finally invo...

journal_title：Acta oto-laryngologica

authors： Kaneko Y,Terayama Y,Kawamoto K,Kasajima K,Ise I

更新日期：1978-11-01 00:00:00