Incorporation of radioactive calcium into otolithic membranes and middle ear ossicles of the gerbil.

Abstract:

:45CaCl2 was injected into gerbils in single or multiple doses, and the resulting radioactivity in serum, otoconial CaCO3, bone samples, and selected labyrinthine epithelium was determined by liquid scintillation spectrometry. Incorporation into both utricular and saccular otoconia occurred at the rate of 0.06-0.07 nmole Ca++ per day, corresponding to a fractional rate of uptake of 0.1%. The retention of radioactivity had a half-life of approximately 11 days. The rate of incorporation of calcium for the middle ear ossicles was 5-7 times that for otoconia and was similar to that for otic capsule and skeletal bone. The level of 45Ca++ was higher in the pigmented regions of the utricular membranous wall than in the non-pigmented areas of the utricular and ampullary wall and in the stria vascularis.

journal_name

Acta Otolaryngol

journal_title

Acta oto-laryngologica

authors

Preston RE,Johnsson LG,Hill JH,Schacht J

doi

10.3109/00016487509121327

subject

Has Abstract

pub_date

1975-09-01 00:00:00

pages

269-75

issue

3-4

eissn

0001-6489

issn

1651-2251

journal_volume

80

pub_type

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