Cytotoxic and genotoxic effects of paclitaxel (Taxol) and radiation in a squamous cell carcinoma cell line of the larynx.

abstract：:In experimental autoimmune labyrinthitis, we found that the guinea pigs sensitized with bovine inner ear antigen (IEAg) developed cellular infiltration within the endolymphatic sac (E. sac). In this study, we investigated the distribution of immune mediated cells within bony vascular channels. The channels, which are ...

journal_title：Acta oto-laryngologica

authors： Yamanobe S,Harris JP,Keithley EM

更新日期：1993-03-01 00:00:00

abstract：:The ultrastructure of the geniculate ganglion was studied in the guinea pig and monkey. Two cytologically distinct colonies of ganglion cells were seen and identified as light and dark cells. All neurons were unmyelinated and most were unipolar, although a few bipolar cells were seen. The axons, upon leaving the cell ...

journal_title：Acta oto-laryngologica

authors： Kitamura K,Kimura RS,Schuknecht HF

更新日期：1982-01-01 00:00:00

abstract：:The muscle fiber content of the stapedius muscle of the cat was determined histochemically using a combination of oxidative enzymes and glycolytic markers. The major fiber type present was determined to be the fast oxidative glycolytic type (FOG; 77%). Two other types of fiber were found that could not be placed into ...

journal_title：Acta oto-laryngologica

authors： Lyon MJ,Malmgren LT

更新日期：1982-07-01 00:00:00

abstract：:The present study on the anatomy of the human facial nerve is based on the results of a series of gross dissections, and histological and electro-diagnostic examinations. From our findings it follows that there is a definite spatial orientation of the peripheral branches in the facial nerve trunk. The results of the m...

journal_title：Acta oto-laryngologica

authors： Podvinec M,Pfaltz CR

更新日期：1976-03-01 00:00:00

abstract：:The production of middle ear effusion by mechanical stimulation was studied in sympathectomized and vagotomized animals. Mechanical stimulation was obtained by a 14 degree C airstream in the external auditory canal. In sympathectomized animals this procedure caused effusion production and vasoconstriction of pars flac...

journal_title：Acta oto-laryngologica

authors： Goldie P,Hellström S

更新日期：1988-07-01 00:00:00

abstract：BACKGROUND:Laryngeal squamous cell carcinoma (LSCC) is rare in the young. OBJECTIVES:We characterized the clinical behavior of LSCC and assessed the presentation of second primary tumors (SPCs) in this patient population. MATERIALS AND METHODS:Data from the Finnish Cancer Registry (FCR) were used to identify an epide...

journal_title：Acta oto-laryngologica

authors： Silén S,Haapaniemi A,Dickinson A,Rönn K,Mäkitie A

更新日期：2019-01-01 00:00:00

abstract：:Laryngoscopy in cases of sulcus vocalis reveals bowed vocal folds, resulting in a spindle-shaped chink with glottal incompetence. The anatomic and functional problems and resulting incomplete glottal closure during phonation lead to the presenting symptoms of breathy hoarseness, decrease in maximum phonation time (MPT...

journal_title：Acta oto-laryngologica

authors： Tsunoda K,Fujimaki Y,Nito T,Yamasoba T,Tayama N,Makiyama K,Murofushi T,Tsunoda A,Ohshima K,Nishiyama K,Kano S,Niimi S

更新日期：2015-06-01 00:00:00

abstract：:Voluntary control of the human vestibulo-ocular reflex with and without visual targets was investigated. Subjects were rotated sinusoidally from 0.1 to 1.0 Hz using d.c. electro-oculography to record eye position. The ratio of eye to head movement, or gain, of the vestibulo-ocular reflex was measured. When subjects we...

journal_title：Acta oto-laryngologica

authors： Barr CC,Schultheis LW,Robinson DA

更新日期：1976-05-01 00:00:00

abstract：CONCLUSION:In the mouse, when a tympanic perforation is present, gadoteridol does not seem to cause ototoxicity. Gadodiamide may cause mild ototoxicity other than toxicity to the outer hair cells of the cochlea. OBJECTIVES:Endolymphatic hydrops have been visualized through intra-tympanic injection of gadolinium-based ...

journal_title：Acta oto-laryngologica

authors： Nonoyama H,Tanigawa T,Shibata R,Tanaka H,Katahira N,Horibe Y,Takemura K,Murotani K,Ozeki N,Ueda H

更新日期：2016-11-01 00:00:00

abstract：CONCLUSION:The prognosis of the clinically positive neck in temporal bone squamous cell carcinoma is bad and failures never occur in the neck but at the site of the primary. A clinically positive neck at presentation is a sign of aggressiveness of the primary and, in such cases, therapeutic neck dissection is to be per...

journal_title：Acta oto-laryngologica

authors： Zanoletti E,Danesi G

更新日期：2010-08-01 00:00:00

abstract：:The aim of this study was to investigate the influence of weather conditions on the frequency of acute laryngitis in adults. The medical records of 825 patients with a diagnosis of acute laryngitis obtained over a 5-year period were reviewed. Meteorological data reviewed included the daily values of 13 parameters. The...

journal_title：Acta oto-laryngologica

authors： Danielides V,Nousia CS,Patrikakos G,Bartzokas A,Lolis CJ,Milionis HJ,Skevas A

更新日期：2002-09-01 00:00:00

abstract：CONCLUSION:The existence of patients with positive non-sentinel node indicates a risk of misdiagnosis of metastasis in oropharyngeal and oral cancer. OBJECTIVES:We attempted to confirm the usefulness of sentinel lymph node biopsy (SLNB) in oropharyngeal and oral cavity cancer to detect clinically occult metastases. P...

journal_title：Acta oto-laryngologica

authors： Santaolalla F,Sanchez JM,Ereño C,Gonzalez A,Rodriguez ML,Sanchez A,Martinez A

更新日期：2008-10-01 00:00:00

abstract：:Ionic mechanisms sustaining sensory transduction in crista ampullaris sensory cells have been investigated chiefly by replacing the endolymph with solutions with K+ and Ca++ chelators added. The effects of the modified solutions were evaluated by extracellular and intracellular recordings of both and the presynaptic a...

journal_title：Acta oto-laryngologica

authors： Zucca G,Valli P,Casella C

更新日期：1982-05-01 00:00:00

abstract：:It has previously been shown that simple compounds with multiple amine groups are ototoxic, the degree of ototoxicity depending on the number of amine groups in the molecule. The relationship between the number of amino groups and ototoxicity in aminoglycoside was studied using kanamycin A and kanamycin B, which conta...

journal_title：Acta oto-laryngologica

authors： Yung MW

更新日期：1987-01-01 00:00:00

abstract：:One hundred fifty-three cases of acoustic neuroma were treated surgically by the middle cranial fossa approach or extended middle cranial fossa approach. Attempts to preserve hearing were made in 30 cases with tumours extending 2.0 cm or less into the posterior fossa; successful hearing preservation was achieved in 12...

journal_title：Acta oto-laryngologica

authors： Kanzaki J,Ogawa K,Shiobara R,Toya S

更新日期：1989-05-01 00:00:00

abstract：:The influence of posture on nasal cavity geometry was studied by acoustic rhinometry in 14 normal adult subjects. On adopting a supine position from sitting the volume of the initially more patulous nasal cavity decreased and the volume of the less patulous side increased. These changes in volume are statistically sig...

journal_title：Acta oto-laryngologica

authors： O'Flynn P

更新日期：1993-07-01 00:00:00

abstract：:The vestibular and optokinetic responses of a group of white cats were evaluated and compared with the responses from a control group of pigmented animals. The results indicate that in all cases the white cats exhibited varying degrees of vestibular and/or optokinetic dysfunction, which in some animals varied from tes...

journal_title：Acta oto-laryngologica

authors： Waldorf RA,Polsinelli DJ,Knister JR,Kohut RI

更新日期：1977-07-01 00:00:00

abstract：CONCLUSION:Coexistent migraine affects relevant clinical features of patients with Ménière's disease (MD). OBJECTIVE:Epidemiological studies have shown an association between migraine and MD. We sought to determine whether the coexistence of migraine affects any clinical features in patients with MD. PATIENTS AND MET...

journal_title：Acta oto-laryngologica

authors： Cha YH,Brodsky J,Ishiyama G,Sabatti C,Baloh RW

更新日期：2007-12-01 00:00:00

abstract：:The objective of this study was to examine the outcome of unilateral stapes surgery in one patient group with bilateral hearing loss and one group with unilateral hearing loss. The patients' own estimations of improvement in hearing ability and the occurrence of other ear-related symptoms were examined retrospectively...

journal_title：Acta oto-laryngologica

authors： Lundman L,Mendel L,Bagger-Sjöbäck D,Rosenhall U

更新日期：1999-01-01 00:00:00

abstract：:T lymphocytes from tonsil (To) and peripheral blood (PB) of 4 tonsillectomized children were subjected to clonal expansion with PHA in order to analyze at single cell level their cytolytic activity and their ability to produce interleukins such as IL-2, IFN-gamma and IL-4. Analyzing all T-cell clones (CD4+ and CD8+) o...

journal_title：Acta oto-laryngologica

authors： Gallo O,De Carli M,Gallina E,Toccafondi G,Romagnani S,Del Prete G

更新日期：1991-01-01 00:00:00

abstract：:Background: Neutrophil-to-lymphocyte ratio (NLR) has emerged as a marker for degree of inflammation. Inflammation has been regarded as one of the causes of idiopathic sudden sensorineural hearing loss.Objectives: This study investigated the potential association between neutrophil-to-lymphocyte ratio (NLR) and prognos...

journal_title：Acta oto-laryngologica

authors： Kang JW,Kim MG,Kim SS,Im HI,Dong SH,Kim SH,Yeo SG

更新日期：2020-04-01 00:00:00

abstract：:Malignant laryngeal tumours with spindle-cell morphology are relatively rare. Differential diagnosis of spindle-cell carcinoma, leiomyosarcoma, fibrosarcoma, rhabdomyosarcoma, malignant melanoma and inflammatory myofibroblastic tumour may be particularly difficult. Ambiguous and indeterminate diagnoses are also possib...

journal_title：Acta oto-laryngologica

authors： Marioni G,Bottin R,Staffieri A,Altavilla G

更新日期：2003-01-01 00:00:00

abstract：CONCLUSION:Cochlear implantation is a safe procedure in experienced hands, as the rate of severe complications is below 2%. Complications differ between children and adults, and transient disequilibrium/vertigo is the most common complication, followed by wound infection, haematoma/oedema and transient chorda tympani s...

journal_title：Acta oto-laryngologica

authors： Hansen S,Anthonsen K,Stangerup SE,Jensen JH,Thomsen J,Cayé-Thomasen P

更新日期：2010-05-01 00:00:00

abstract：:Contact endoscopy allows an in vivo and in situ study of the superficial layers of the vocal cord epithelium. This technique offers access to some characteristics of the epithelium cells: dimension and shape of the nuclei, nucleus/cytoplasm ratio, keratosis, presence of nucleolus, mitosis and koylocites. Contact endos...

journal_title：Acta oto-laryngologica

authors： Andrea M,Dias O,Santos A

更新日期：1995-03-01 00:00:00

abstract：:The blowing of chilled (14 degrees C) air into the external auditory canal (EAC) resulted in a profuse middle ear fluid production. The stimulation caused marked changes in the pars flaccida of the tympanic membrane. A slight vasodilatation was noted in the oedematous loose connective tissue layer of the pars flaccida...

journal_title：Acta oto-laryngologica

authors： Goldie P,Hellström S

更新日期：1986-09-01 00:00:00

abstract：:Background: In otosclerosis mixed hearing loss is the most frequent symptom and arises when the focus involves the stapes footplate. Surgeons usually prefer to wait a minimum air-bone gap of 25 - 35 dB before surgery.Objectives: To evaluate the outcome of microdrill stapedotomy for otosclerosis in patients with a preo...

journal_title：Acta oto-laryngologica

authors： Canale A,Albera A,Macocco F,Caranzano F,Albera R

更新日期：2020-09-01 00:00:00

abstract：OBJECTIVE:To ascertain whether a daily nasal spray with physiological saline could prevent symptoms of common cold in a population of otherwise healthy adults. MATERIAL AND METHODS:This was study involving 10 weeks of daily use of a nasal saline spray and 10 weeks of only recording symptoms. Young adults eligible for ...

journal_title：Acta oto-laryngologica

authors： Tano L,Tano K

更新日期：2004-11-01 00:00:00

abstract：OBJECTIVES:The authors would like to confirm a fluid pathway from the scala tympani to the organ of Corti, and to observe its morphological changes. METHODS:A staining solution for succinic dehydrogenase was perfused with phenazine methosulfate in the scala tympani of living guinea pigs (n = 5) under deep anesthesia. ...

journal_title：Acta oto-laryngologica

authors： Nomura Y,Kimura Y,Kobayashi H

更新日期：2016-11-01 00:00:00

abstract：BACKGROUND:Many patients with coronavirus disease 2019 (COVID-19) complain from olfactory dysfunction (OD). Aims/objectives: To evaluate the prevalence, prognosis, and recovery from OD in COVID-19 patients. MATERIAL AND METHODS:In this study, patients with COVID-19 symptoms who were referred to six different tertiary ...

journal_title：Acta oto-laryngologica

authors： Samimi Ardestani SH,Mohammadi Ardehali M,Rabbani Anari M,Rahmaty B,Erfanian R,Akbari M,Motedayen Z,Samimi Niya F,Aminloo R,Farahbakhsh F,Hosseininasab A,Hassanlouei B,Rezaian N,Mokhtari Z

更新日期：2020-11-11 00:00:00

abstract：CONCLUSIONS:The heparin-binding epidermal growth factor-like growth factor (HB-EGF) plays an essential role in the development and invasiveness of cholesteatoma. This study may help to realize the molecular mechanisms underlying the pathogenesis of cholesteatoma and make HB-EGF a promising target for drug intervention ...

journal_title：Acta oto-laryngologica

authors： Xie S,Wang X,Ren H,Liu X,Ren J,Liu W

更新日期：2017-08-01 00:00:00