Abstract:
:Ionic mechanisms sustaining sensory transduction in crista ampullaris sensory cells have been investigated chiefly by replacing the endolymph with solutions with K+ and Ca++ chelators added. The effects of the modified solutions were evaluated by extracellular and intracellular recordings of both and the presynaptic and postsynaptic activity of ampullar receptors. The results strongly suggest that the receptor current in labyrinthine cells is carried exclusively by K+. Moreover evidence are reported indicating that the transducer membrane in ampullar receptors is provided with Ca++ sensitive potassium channels whose opening is depending on free Ca++ released from cupular structures during excitatory deflections.
journal_name
Acta Otolaryngoljournal_title
Acta oto-laryngologicaauthors
Zucca G,Valli P,Casella Cdoi
10.3109/00016488209130893subject
Has Abstractpub_date
1982-05-01 00:00:00pages
355-62issue
5-6eissn
0001-6489issn
1651-2251journal_volume
93pub_type
杂志文章abstract::In experimental autoimmune labyrinthitis, we found that the guinea pigs sensitized with bovine inner ear antigen (IEAg) developed cellular infiltration within the endolymphatic sac (E. sac). In this study, we investigated the distribution of immune mediated cells within bony vascular channels. The channels, which are ...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489309135786
更新日期:1993-03-01 00:00:00
abstract::Background: If the pulsatile tinnitus caused by sigmoid sinus diverticulum/dehiscence cannot be diagnosed and treated, it can lead to significant morbidity and mortality.Aim: To assess the sandwich surgical technique for sigmoid sinus wall reconstruction for the treatment of pulsatile tinnitus caused by sigmoid sinus ...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016489.2019.1668960
更新日期:2019-12-01 00:00:00
abstract:CONCLUSION:Vestibular disturbance is frequent, but mild even immediately after stapes surgery. Vestibular symptoms improved or disappeared quickly, and they did not correlate with nystagmus. Outpatient stapes surgery performed under local anaesthesia is a feasible approach. OBJECTIVE:Vestibular symptoms are common and...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489.2013.782106
更新日期:2013-08-01 00:00:00
abstract::Using primary cultures of marginal cells of stria vascularis from guinea pig and gerbil, ionic channels located on the luminal membrane were investigated by means of patch clamp technique. Recordings were performed in cell-attached and inside-out configurations. In cell-attached configuration, single channel activity ...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489109137391
更新日期:1991-01-01 00:00:00
abstract::Most epidemiological surveys concerning populations exposed to occupational noise or random populations have shown that the left ear is slightly but significantly poorer than the right ear, especially at frequencies most susceptible to noise damage. To experimentally study the possible left-right asymmetry in response...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489109138399
更新日期:1991-01-01 00:00:00
abstract::Aspiration biopsy is an accurate but still a somewhat controversial method of diagnosing salivary gland tumours preoperatively. During the last few years this method has been more and more accepted dependent on its increasing reliability in diagnosing the different types of tumours, but for an adequate treatment it is...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016487609107505
更新日期:1976-05-01 00:00:00
abstract:OBJECTIVE:To investigate whether the extent of expression of hyaluronan (HA) and epidermal growth factor receptor (EGFR) in squamous cell carcinoma of the mobile tongue can predict the risk of cervical metastasis and survival. STUDY DESIGN:Retrospective histopathologic study. METHODS:Surgical specimens from 64 patien...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016489.2017.1292049
更新日期:2017-08-01 00:00:00
abstract::The electromagnetic interference of the recently introduced bone-anchored hearing aid (BAHA) model "BAHA Compact" by digital cellular phones is investigated and compared with that of the older "BAHA Classic 300" model. Measurements with two different digital cellular phones in a laboratory setting indicated that the n...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016480260092318
更新日期:2002-07-01 00:00:00
abstract:CONCLUSION:These findings indicate a strong protective effect of ALCAR and NAC on impulse noise-induced cochlear damage, and suggest the feasibility of using clinically available antioxidant compounds to protect the ear from acute acoustic injury. OBJECTIVE:Reactive oxygen species have been shown to play a significant...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016480410023038
更新日期:2005-03-01 00:00:00
abstract:CONCLUSION:The narrowing pattern of the upper airway in obstructive sleep apnea patients may be different in sleep as compared with awake. Three different types of obstruction were observed in these subjects during drug-induced sleep. The different obstruction pattern during drug-induced sleep suggests that different s...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016480902780242
更新日期:2009-12-01 00:00:00
abstract:BACKGROUND:Benign paroxysmal positional vertigo (BPPV) is the most common type of peripheral vertigo. This study aimed to evaluate the effects of the Semont maneuver (SM) for BPPV treatment, compared with other methods. METHODS:Studies were selected in relevant databases under pre-defined criteria up to June 2015. The...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章,meta分析
doi:10.1080/00016489.2016.1212265
更新日期:2017-01-01 00:00:00
abstract:OBJECTIVE:To evaluate the capability of indirect computed tomography and magnetic resonance lymphography (CT/MR-LG) with gadolinium-loaded, polyethylenimine-entrapped gold nanoprobes (Gd-Au PENPs) for assessing lingual sentinel lymph node (SLN) metastasis in a tongue VX2 carcinoma model. MATERIALS AND METHODS:Seventee...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016489.2018.1441544
更新日期:2018-08-01 00:00:00
abstract::A method is described for the intravital microscopic observations of rabbit tracheal mucosa microcirculation during compression with a thin, transparent high volume cuff. The cuff pressure (CP) required to cause complete ischemia in the mucosa over the cartilages was measured and a correlation was found to the mean ar...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016487909137192
更新日期:1979-01-01 00:00:00
abstract::We previously reported that long-term exposure to glutamate (Glu) induced death of cochlear outer hair cells (OHCs). However, the mechanisms of OHC death induced by Glu were unclear. In the central nervous system, Glu is known to interfere with a cystine-Glu antiporter, leading to a decrease in cystine uptake and redu...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016489950180612
更新日期:1999-01-01 00:00:00
abstract:CONCLUSIONS:Endoscopic laser microsurgery (ELM) provides comparable oncological outcomes, and improved functional recovery and laryngeal preservation compared with open partial laryngopharyngectomy (OPLP) in patients with early squamous cell carcinoma of the hypopharynx (HPSCC). The use of open surgery is declining. Th...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489.2013.805341
更新日期:2013-10-01 00:00:00
abstract::There is no single technique for reconstruction of the canal wall following radical mastoidectomy. Autograft tissues may be unsuitable because of resorption and limited availability. An ideal foreign implant material should be bone-like in quality, non-ototoxic, readily available and malleable. Plaster of Paris, a deg...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016488609108631
更新日期:1986-05-01 00:00:00
abstract::The early diagnosis of the Mondini dysplasia by means of electrocochleography and temporal bone polytomography, and the prevention of further hearing loss through the endolymphatic subarachnoid shunt operation, brought new data on the follow-up of patients with this malformation. They were found to present specific me...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016488309139454
更新日期:1983-05-01 00:00:00
abstract::Dysphagia is a common presenting complaint in otolaryngology practice, and there are many causes. Forestier syndrome is a rare cause of dysphagia. It is also known as diffuse idiopathic skeletal hyperostosis (DISH) syndrome or vertebral ankylosing hyperostosis. Forestier syndrome consists of anterolateral perivertebra...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016480500504192
更新日期:2006-07-01 00:00:00
abstract:OBJECTIVES:The aim of this prospective study was to assess the usefulness of nasal smear eosinophilia compared with a skin sensitivity test for the diagnosis of allergic rhinitis and to determine the degree of correlation between the tests. MATERIAL AND METHODS:Fifty patients with a clinical history suggestive of nasa...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016480310002159
更新日期:2003-12-01 00:00:00
abstract:CONCLUSION:The prognosis of the clinically positive neck in temporal bone squamous cell carcinoma is bad and failures never occur in the neck but at the site of the primary. A clinically positive neck at presentation is a sign of aggressiveness of the primary and, in such cases, therapeutic neck dissection is to be per...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016480903390152
更新日期:2010-08-01 00:00:00
abstract:CONCLUSIONS:We used a feedback method, based on a blood pressure manometer with inflatable cuff, to control the sternocleidomastoid muscle (SCM) contraction. To obtain comparable left-right VEMP responses, it is necessary (1) to determine which cuff pressures on both sides yield identical mean rectified voltage (MRV) v...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016480500527227
更新日期:2006-08-01 00:00:00
abstract::The present study further assessed the role of the endolymphatic sac (E.S.) in the generation of inner ear immune responses. Guinea pigs underwent unilateral endolymphatic sac obliteration (Rt) and the opposite ears (Lt) served as controls. The animals were then systemi-cally sensitized to KLII and both inner ears wer...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016488709107782
更新日期:1987-05-01 00:00:00
abstract::Little is known about the physiologic regulation of the vestibular end organ blood flow. The purpose of the current study was to examine posterior semicircular canal ampulla blood flow in addition to systemic factors during intravenous infusions of calcitonin-gene related peptide (CGRP), a factor involved in the tonic...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489709114207
更新日期:1997-11-01 00:00:00
abstract::Mucormycosis is a rare acute fatal fungal infection. It is typically observed in diabetic or immunocompromised patients but not in systemically healthy individuals. Here, we describe an unusual mucormycosis case in an immunocompetent patient who had clinical signs of a maxillary sinusitis and associated osteomyelitis ...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016480500534439
更新日期:2006-09-01 00:00:00
abstract::A comparison was made between polysomnographic recordings and recordings of airflow pressures in the pharynx and respiratory pressures in the esophagus of 10 adult sleeping subjects with differing degrees of apnea. Pressure measurements were obtained by microsensors mounted on a 7F gauge flexible catheter which sited ...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489509139346
更新日期:1995-05-01 00:00:00
abstract::We studied the influence of neck afferents on the perception of orientation. In Experiment 1, we investigated the effect of head tilt on the subjective vertical in both the visual and tactile modalities. The results showed that head tilt triggers an Aubert effect in the visual modality and a Müller effect in the tacti...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/000164800750000261
更新日期:2000-09-01 00:00:00
abstract:CONCLUSIONS:The adenovirus-5 vector specifically transduced spiral ganglion cells with high efficiency, suggesting that it is a potential gene therapeutic tool for the survival of spiral ganglion cells with secondary injury. OBJECTIVES:This study aimed to find a suitable viral vector allowing efficient transduction to...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016480903510742
更新日期:2010-07-01 00:00:00
abstract::This is a study of the effects of repeated angular acceleration on the activity of vestibular nuclei units in anesthetized and in conscious cats. The experimental animals were subjected to trains of repeated and consecutive constant acceleration-deceleration ramps (4-8 degrees/sec2). In a few cases nystagmus was recor...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016488009131713
更新日期:1980-09-01 00:00:00
abstract::EMG recordings of the neck muscles (biventer cervicis, complexus, splenius, longus capitis) of decerebrate cats were obtained during pitch and roll stimulations (sinusoidal stimulation: 30 degrees p-p amplitude, 0.2 Hz frequency). Most of the EMG responses to pitch showed activation peaks leading the position stimuli ...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489309135800
更新日期:1993-05-01 00:00:00
abstract:CONCLUSIONS:The intra-tumoral cytokines IL-6, hepatocyte growth factor (HGF) and tumour necrosis factor-a (TNF-a) stimulate oral cancer cells to enhanced secretion of matrix metalloproteinase (MMP)-1 and -9. These results contribute to an understanding of the extracellular events necessary for tumour progression. OBJE...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016480510027484
更新日期:2005-07-01 00:00:00