Luminal non-specific cationic channels in cultured strial marginal cells of guinea pig and gerbil as determined by patch clamp technique.

abstract：:Histology, histogenesis, biology and treatment of the rare spindle cell carcinoma of the larynx are presented. The histogenesis of spindle cell tumours has been much debated, but electron microscopic investigations have shown that most of the laryngeal lesions are squamous epithelial carcinomas that have undergone tra...

journal_title：Acta oto-laryngologica

authors： Katholm M,Krogdahl A,Hainau B,Bretlau P

更新日期：1984-07-01 00:00:00

abstract：:The waltzing guinea pig exhibits genetically induced inner ear disease which develops into deafness and vestibular disorder. The type I hair cell in vestibular end organs shows specific pathology, featuring protrusion of the hair cell apex, sensory hair fusion and an intracellular actin filament rod. With the freeze-f...

journal_title：Acta oto-laryngologica

authors： Sobin A,Flock A,Bagger-Sjöbäck D

更新日期：1983-09-01 00:00:00

abstract：:Intense sound stimulation may result in excessive glutamate release from the inner hair cells, resulting in binding to the postsynaptic glutamate receptors and leading to neuronal degeneration and functional impairment. In this study we investigated the therapeutic effect and time window of caroverine, an N-methyl-D-a...

journal_title：Acta oto-laryngologica

authors： Chen Z,Ulfendahl M,Ruan R,Tan L,Duan M

更新日期：2003-10-01 00:00:00

abstract：:This paper presents the results of an investigation into the possibility that gangliosides (brain cortex glycosphingolipids) are capable of being functionally incorporated into cell membranes and of interfering with enzymatic activity of the ATPase system on the stria vascularis and spiral ligament in the guinea pig. ...

journal_title：Acta oto-laryngologica

authors： Aporti F,Facci L,Pastorello A,Siliprandi R,Savastano M,Molinari G

更新日期：1981-11-01 00:00:00

abstract：:The objective of this study was to determine whether methylcobalamin inhibits the ototoxic action of gentamicin. Fourteen pigmented guinea pigs were randomly divided into experimental and control groups. Each animal in the experimental group was given a large single dose of gentamicin (125 mg/kg i.m.), followed by imm...

journal_title：Acta oto-laryngologica

authors： Jin X,Jin X,Sheng X

更新日期：2001-04-01 00:00:00

abstract：:The inner ear of mutant bustling mice, BUS/Idr, was examined histopathologically. LM examinations revealed an age-dependent degeneration of the auditory organ of Corti in BUS homozygotes, but not heterozygotes. Cochlear base-to-apex gradient in severity of the degeneration was noted. First signs of degeneration were f...

journal_title：Acta oto-laryngologica

authors： Yonezawa S,Nodasaka Y,Kamada T,Fujita SC,Kato K,Yamada Y,Ogasawara N,Shoji R

更新日期：1996-05-01 00:00:00

abstract：:Ciliogenesis events in human vestibular epithelia develop as an asynchronous process between neighbouring cells, but it is a synchronous one within each sensory cell, presenting the following stages. Initially, the cilia buds appear as stubby cylinders well aligned on the cuticular plate of the presumptive sensory cel...

journal_title：Acta oto-laryngologica

authors： Sánchez-Fernández JM,Rivera-Pomar JM

更新日期：1985-03-01 00:00:00

abstract：:In human temporal bone specimens the vibrations of the labyrinthine fluid were measured by a piezoelectric system after application of various techniques of otosclerosis surgery. Compared with the amplitude in the case of a normal stapes, the surgical techniques according to Zangemeister, Shea and Schuknect resulted i...

journal_title：Acta oto-laryngologica

authors： Cancura W

更新日期：1975-01-01 00:00:00

abstract：:As part of an early intervention study on the acceptability of auditory rehabilitative intervention, we examined patient complaints and clinical findings of balance disorders. Hallam et al. have discussed desynchrony between such findings in hospital patient populations, and the aim of the present study was to investi...

journal_title：Acta oto-laryngologica

authors： Stephens SD,Hogan S,Meredith R

更新日期：1991-01-01 00:00:00

abstract：OBJECTIVE:To investigate the positive rate for the Cochlin tomo-protein (CTP: an inner ear-specific protein) detection test among patients with inner ear-related clinical manifestations and evaluate the clinical characteristics of definite perilymphatic fistula (PLF). METHODS:We have performed an ELISA-based CTP detec...

journal_title：Acta oto-laryngologica

authors： Matsuda H,Sakamoto K,Matsumura T,Saito S,Shindo S,Fukushima K,Nishio SY,Kitoh R,Shibasaki O,Ito A,Araki R,Usami SI,Suzuki M,Ogawa K,Hasegawa T,Hagiwara Y,Kase Y,Ikezono T

更新日期：2017-01-01 00:00:00

abstract：CONCLUSIONS:This is the first report of mandibular reconstruction using the retroauricular (RA) or the modified face-lift (MFL) approach in head and neck cancer. This approach may have advantages over the conventional approach, especially in its superior aesthetic results. OBJECTIVE:The fibular osseous or osteocutaneo...

journal_title：Acta oto-laryngologica

authors： Kim WS,Jittreetat T,Nam W,Sannikorn P,Choi EC,Koh YW

更新日期：2015-05-01 00:00:00

abstract：:The ultrastructure of the geniculate ganglion was studied in the guinea pig and monkey. Two cytologically distinct colonies of ganglion cells were seen and identified as light and dark cells. All neurons were unmyelinated and most were unipolar, although a few bipolar cells were seen. The axons, upon leaving the cell ...

journal_title：Acta oto-laryngologica

authors： Kitamura K,Kimura RS,Schuknecht HF

更新日期：1982-01-01 00:00:00

abstract：:Nl action potentials, elicited by low-level, 4.0-kHz filtered clicks, were recorded from the ear canals of normal-hearing adults. Responses were recorded at two sensation levels in the presence and absence of a pure tone delivered to the contralateral ear. Waveforms were analysed for changes in amplitude and latency. ...

journal_title：Acta oto-laryngologica

authors： Folsom RC,Owsley RM

更新日期：1987-05-01 00:00:00

abstract：CONCLUSION:The increased AQP5 expression associated with ageing in glands, which mainly secreted a serous solution, suggests a compensation for the decreased amount of saliva secretion associated with age progression. OBJECTIVE:To investigate the change in aquaporin-1 (AQP1) and aquaporin-5 (AQP5) expression in the sa...

journal_title：Acta oto-laryngologica

authors： Sapmaz E,Uysal M,Tumer MK,Sapmaz HI,Somuk BT,Arici A,Tas U

更新日期：2016-09-01 00:00:00

abstract：:In experimental autoimmune labyrinthitis, we found that the guinea pigs sensitized with bovine inner ear antigen (IEAg) developed cellular infiltration within the endolymphatic sac (E. sac). In this study, we investigated the distribution of immune mediated cells within bony vascular channels. The channels, which are ...

journal_title：Acta oto-laryngologica

authors： Yamanobe S,Harris JP,Keithley EM

更新日期：1993-03-01 00:00:00

abstract：CONCLUSIONS:The expression of phosphorylcholine (ChoP) in the surface of nontypeable Haemophilus influenzae (NTHi) is an important factor in the pathogenesis of persistent otitis media with effusion (OME) in humans. OBJECTIVES:Lipooligosaccharide (LOS) in NTHi undergoes phase variation in expression of the ChoP epitop...

journal_title：Acta oto-laryngologica

authors： Fujita K,Hirano T,Kodama S,Suzuki M

更新日期：2009-08-01 00:00:00

abstract：:We examined the mucosa of 50 rat middle ears in an experimental model of acute otitis media, in order to obtain information on the mechanisms of polyp formation. The right middle ear of 25 rats was inoculated with type 3 pneumococci, and the left ear served as a control. The animals were killed, the middle ear bulla r...

journal_title：Acta oto-laryngologica

authors： Cayé-Thomasen P,Hermansson A,Tos M,Prellner K

更新日期：1995-01-01 00:00:00

abstract：:The biocompatibility of commercially available polyimides was examined in relation to the sensory and neural structures of the cochlea. Thin films of four different polyimides were prepared as substrates for photolithographically produced scala tympani electrode arrays and implanted in 32 cat cochleae. Following at le...

journal_title：Acta oto-laryngologica

authors： Haggerty HS,Lusted HS

更新日期：1989-01-01 00:00:00

abstract：:The expression of vascular cell adhesion molecule-1 (VCAM-1), alpha4-integrin and L-selectin was dynamically observed using an immunohistochemical approach during labyrinthitis induced by inoculation of keyhole limpet hemocyanin into the scala tympani of animals that had been systemically sensitized to it. At the same...

journal_title：Acta oto-laryngologica

authors： Zhang C,Huang W,Song H

更新日期：2000-08-01 00:00:00

abstract：:In this study, cytological examination of nasal secretions of 17 patients with cystic fibrosis (CF) was combined with quantitative determination of common inflammatory mediators. Results showed a normal cytogram in these patients. However, obvious mucosal inflammation is evidenced by significantly higher concentration...

journal_title：Acta oto-laryngologica

authors： Wang D,Brihaye P,Smitz J,De Waele M,Clement P

更新日期：1996-05-01 00:00:00

abstract：:The effect of adaptation of the ear on the SISI test was studied at 500 Hz and 2000 Hz in 43 patients with chronic otitis and in 20 patients with otosclerosis. The mean adaptation was slightly over 10 dB, except in the otosclerosis group at 2000 Hz, for which the value was nearly 20 dB after continuous stimulation at ...

journal_title：Acta oto-laryngologica

authors： Rahko T

更新日期：1975-07-01 00:00:00

abstract：:Background: The incidence of oropharyngeal squamous cell carcinoma (OPSCC) has been rising in the Western world in recent years. Human papillomavirus (HPV) infection is established as the main explanation.Aims/objectives: This study aims to review the most recently published studies on the repartition of HPV-positive ...

journal_title：Acta oto-laryngologica

authors： Stjernstrøm KD,Jensen JS,Jakobsen KK,Grønhøj C,von Buchwald C

更新日期：2019-12-01 00:00:00

abstract：CONCLUSION:The use of both gadolinium chloride (GdCl(3)) and osmium tetroxide (OsO(4)) allowed for the visualization of the membranous labyrinth and other intralabyrinthine structures, at different intensities, as compared with the control sample. This initial comparison shows the advantages of GdCl(3) in radiological ...

journal_title：Acta oto-laryngologica

authors： Wong CC,Curthoys IS,O'Leary SJ,Jones AS

更新日期：2013-01-01 00:00:00

abstract：CONCLUSION:Partial deafness cochlear implantation (PDCI) is a feasible means of treating individuals who have good low frequency hearing, but a severe to profound hearing loss in the mid to high frequencies. The individuals have benefit in noise and show significant benefit in a number of difficult listening conditions...

journal_title：Acta oto-laryngologica

authors： Skarzynski H,Lorens A,Piotrowska A,Anderson I

更新日期：2006-09-01 00:00:00

abstract：:IL2Rs, in the presence of IL2, mediate activation and proliferation of human normal lymphocytes and modulate functional changes of some human leukocytic malignancies. IL2Rs have been demonstrated also on human neoplastic and fetal non-hematologic cells in vitro, although their functional role has not been described. W...

journal_title：Acta oto-laryngologica

authors： Cortesina G,Sacchi M,Galeazzi E,Johnson JT,Whiteside TL

更新日期：1992-01-01 00:00:00

abstract：BACKGROUND:The balloon catheter has been used for a decade to dilate paranasal sinus outflow tracts. The question is: how wide and how durable is the dilation of drainage pathways in patients in long-term observations after this procedure? OBJECTIVE:The objective of our study was to observe the changes occurring in th...

journal_title：Acta oto-laryngologica

authors： Szczygielski K,Galusza B,Rapiejko P,Klopotek M,Jurkiewicz D

更新日期：2017-09-01 00:00:00

abstract：:The early diagnosis of the Mondini dysplasia by means of electrocochleography and temporal bone polytomography, and the prevention of further hearing loss through the endolymphatic subarachnoid shunt operation, brought new data on the follow-up of patients with this malformation. They were found to present specific me...

journal_title：Acta oto-laryngologica

authors： Mangabeira-Albernaz PL

更新日期：1983-05-01 00:00:00

abstract：BACKGROUND:Laryngeal squamous cell carcinoma (LSCC) is rare in the young. OBJECTIVES:We characterized the clinical behavior of LSCC and assessed the presentation of second primary tumors (SPCs) in this patient population. MATERIALS AND METHODS:Data from the Finnish Cancer Registry (FCR) were used to identify an epide...

journal_title：Acta oto-laryngologica

authors： Silén S,Haapaniemi A,Dickinson A,Rönn K,Mäkitie A

更新日期：2019-01-01 00:00:00

abstract：:Cisplatin and gentamicin are two ototoxicants that are supposed to be transported by the paracellar route, i.e. via cellular junctions, to the perilymphatic compartment. This study was initiated to test the hypothesis that susceptive variation of individuals to ototoxic drugs may be explained by variability in transpo...

journal_title：Acta oto-laryngologica

authors： Laurell G,Viberg A,Teixeira M,Sterkers O,Ferrary E

更新日期：2000-10-01 00:00:00

abstract：CONCLUSION:The results suggest that the beneficial effect of astragaloside IV on impulse noise-induced hearing loss may be due to its ability to inhibit reactive oxygen species (ROS) and prevent apoptosis. OBJECTIVE:Astragaloside IV is the major active constituent of Astragalus membranaceus, which has been widely used...

journal_title：Acta oto-laryngologica

authors： Xiong M,He Q,Lai H,Wang J

更新日期：2012-05-01 00:00:00