Abstract:
:This paper presents the results of an investigation into the possibility that gangliosides (brain cortex glycosphingolipids) are capable of being functionally incorporated into cell membranes and of interfering with enzymatic activity of the ATPase system on the stria vascularis and spiral ligament in the guinea pig. Labelled gangliosides (3H-GM1) were incorporated into the cell membranes of the tissues under examination. (Na+, K+)ATPase activity increased l0 minutes after intravenous injection of gangliosides and prevented the decrease in (Na+, K+)ATPase system produced by ethacrynic acid. The action of gangliosides on the (Na+, K+)ATPase system is discussed.
journal_name
Acta Otolaryngoljournal_title
Acta oto-laryngologicaauthors
Aporti F,Facci L,Pastorello A,Siliprandi R,Savastano M,Molinari Gdoi
10.3109/00016488109133282subject
Has Abstractpub_date
1981-11-01 00:00:00pages
433-7issue
5-6eissn
0001-6489issn
1651-2251journal_volume
92pub_type
杂志文章abstract::The distribution of vascular endothelial growth factor (VEGF), one of the most important angiogenic factors, and microvessel density (MVD) were assessed in laryngeal carcinomas by means of immunohistochemistry. Correlation of VEGF with MVD and clinical parameters (T stage, N stage, histological grading, survival, recu...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016489950180711
更新日期:1999-01-01 00:00:00
abstract:CONCLUSION:Although sentinel lymph node (SLN) biopsy is not yet validated for clinical use to replace elective neck dissection in patients with oral squamous cell carcinoma, it can be recommended for patients who do not fulfil the criteria for elective neck treatment according to current treatment protocols. OBJECTIVE...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016480701362002
更新日期:2008-01-01 00:00:00
abstract:CONCLUSION:Partial deafness cochlear implantation (PDCI) is a feasible means of treating individuals who have good low frequency hearing, but a severe to profound hearing loss in the mid to high frequencies. The individuals have benefit in noise and show significant benefit in a number of difficult listening conditions...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016480600606632
更新日期:2006-09-01 00:00:00
abstract::We have recorded auditory evoked potentials, of both neurogenic and myogenic origin, in cats having neonatal high frequency cochlear hearing loss. Using frequency specific stimuli (tone pips) and by measuring responses near to threshold, we have probed tonotopic (or cochleotopic) representation within the brainstem-mi...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489309135763
更新日期:1993-01-01 00:00:00
abstract:CONCLUSION:The prognosis of the clinically positive neck in temporal bone squamous cell carcinoma is bad and failures never occur in the neck but at the site of the primary. A clinically positive neck at presentation is a sign of aggressiveness of the primary and, in such cases, therapeutic neck dissection is to be per...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016480903390152
更新日期:2010-08-01 00:00:00
abstract::The first systematically performed study concerning the size variation of the mastoid air cell system was measured on the X-ray film in a lateral projection, as exposed on the skull table. A new type of equipment (Orbix) with an isocentric motion of the roentgen tube and the film cassette and a different magnification...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016488309130921
更新日期:1983-01-01 00:00:00
abstract::Test-retest variability of values for directional asymmetry in primary and secondary horizontal optokinetic after-nystagmus (OKAN I and OKAN II, respectively) was studied in 16 apparently healthy subjects. OKAN was induced by 60 s of whole-field optokinetic stimulation at speeds of 60 degrees/s and 90 degrees/s in eit...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489209100776
更新日期:1992-01-01 00:00:00
abstract::Five temporal bones and three surgical cochlear nerve specimens from patients who previously underwent labyrinthectomy were studied by light and electron microscopy. All cochleas had nearly total loss of sensory cells, extensive or total loss of both cochlear nerve fibers in the osseous spiral lamina, and spiral gangl...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016488109138495
更新日期:1981-03-01 00:00:00
abstract::The subjective visual horizontal (SVH) was measured by means of a small, rotatable, luminous line in darkness in the upright head and body position and at 10, 20 and 30 degrees of tilt to the right and left before, and repeatedly during a follow-up period of 1 year after intratympanic gentamicin instillations in 12 pa...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016489850154595
更新日期:1998-07-01 00:00:00
abstract::A new generation of cochlear implant electrodes has been designed to position the stimulating contacts close to the modiolus in order to reduce power consumption and increase stimulation selectivity. The purpose of this study was to assess electrode position in the cochlea for three recently designed electrodes. Fifte...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016480260000021
更新日期:2002-06-01 00:00:00
abstract::Central origin of the vidian nerve in the dog was investigated using the retrograde tracing technique of horseradish peroxidase (HRP). After HRP was applied to the vidian nerve, labelled neurons were found in the medulla oblongata and the geniculate ganglion but could not be found in the trigeminal ganglion. Labelled ...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016488309132883
更新日期:1983-07-01 00:00:00
abstract::Several studies have reported variations in shape and size of stereociliary bundles and in a limited number of observations have associated them to type I and type II hair cells. A systematic study has been undertaken for which a technique was developed in order to identify both cell types and their corresponding hair...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489209137453
更新日期:1992-01-01 00:00:00
abstract::From a study of nitric oxide (NO) output in the nose and sinuses it seems that: (i) the results obtained regarding the regulation of NO output in the nose do not necessarily apply to the sinuses; (ii) the results obtained for one group of sinuses may not apply to another; and (iii) NO output in the sinuses does not be...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016480510031524
更新日期:2005-10-01 00:00:00
abstract::The ultrastructure of the epithelial cells of the endolymphatic duct in the rat is described, following vascular perfusion-fixation of live, anaesthetised and artificially respirated animals. The animals were fixed by means of a pressure feed-back controlled peristaltic pump and an isotonic perfusate-fixative containi...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489409126013
更新日期:1994-01-01 00:00:00
abstract::The possible beneficial effects of carbogen gas (95% O2/5% CO2) inhalation on noise-induced permanent cochlear impairment were investigated. Groups of guinea pigs were exposed to daily 3 1/2-hour presentations of 120 dB of broad-band noise in an atmosphere of either carbogen gas or normal air. Other groups received ca...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016488209130889
更新日期:1982-05-01 00:00:00
abstract:CONCLUSION:Neck dissection (ND) may not be warranted for those patients with complete response in the neck. Human papillomavirus (HPV)-positive or -negative tumour does not affect this recommendation. OBJECTIVES:Treatment of tonsillar cancer varies considerably worldwide, although non-surgical treatment, e.g. radiothe...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489.2014.920516
更新日期:2014-10-01 00:00:00
abstract::The penetration of oral erythromycin stearate (Abboticin), administered in a dosage of 500 mg three times a day, into the maxillary sinus mucosa and secretion was studied in 15 patients (22 sinuses) operated on for chronic maxillary sinusitis. The average concentration in serum was 2.3 microgram/ml, 1.2 microgram/ml i...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016487709123970
更新日期:1977-09-01 00:00:00
abstract::Acid base balance changes were observed during 72 h following bilateral nasal obstruction in rats. Mouth breathing caused acute respiratory acidosis and marked aerophagia, leading to spontaneous death of the experimental animal 80 to 90 h postoperatively. Stenotic oropharyngeal airway, due to palatal-epiglottic approx...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489109137406
更新日期:1991-01-01 00:00:00
abstract::The fear of destroying an anticipated growth centre has, with time, induced the postponement of nasal septal operations until adult age. Underdevelopment of the nose and middle face is otherwise believed to be the long-term result. In order to test this hypothesis, subepichondrial surgery was performed in growing dome...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016488509104794
更新日期:1985-09-01 00:00:00
abstract:OBJECTIVE:To investigate whether the extent of expression of hyaluronan (HA) and epidermal growth factor receptor (EGFR) in squamous cell carcinoma of the mobile tongue can predict the risk of cervical metastasis and survival. STUDY DESIGN:Retrospective histopathologic study. METHODS:Surgical specimens from 64 patien...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016489.2017.1292049
更新日期:2017-08-01 00:00:00
abstract::Acoustic rhinometry (AR) evaluates the geometry of the nasal cavity by measuring the minimum cross-sectional area (MCA) and nasal volume (V) by means of acoustic reflection. Understanding the normal and pathologic conditions of the internal nasal cavity using AR is important in the diagnosis of structural abnormalitie...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016480152602311
更新日期:2001-10-01 00:00:00
abstract::Background: The management of patients with tinnitus who receive middle ear surgery has not been established.Aims: The aim of this study is (1) how many patients who receive middle ear surgery have tinnitus and (2) how educational counselling and middle ear surgery is effective with consistent tinnitus.Subjects and me...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016489.2020.1713397
更新日期:2020-04-01 00:00:00
abstract:CONCLUSIONS:Sensorineural hearing loss must be considered within the clinical picture of systemic lupus erythematosus. The results confirm the usefulness of extended high-frequency audiometry in the audiologic testing of these patients, enabling the possibility of modifying or applying a preventive treatment for a poss...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016489.2016.1219049
更新日期:2017-02-01 00:00:00
abstract::In the present study, the protective effect of dexamethasone was analysed following exposure of the cochlea to Pseudomonas aeruginosa Exotoxin A (PaExoA). Four groups of albino Sprague-Dawley rats were used. 20 microl saline was instilled through the tympanic membrane into the round window niche (group A, n = 4); 1 mi...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/000164800750000577
更新日期:2000-03-01 00:00:00
abstract::Lymphangioscopical and ultrastructural studies of the larynx reveal a lymphatic capillary and a collecting vessel system. Collecting vessels show luminal valves and elastic structural components within the wall. Lymphangioscopy reveals that a strict compartmentation of different laryngeal areas is unjustifiable with t...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016488009127137
更新日期:1980-03-01 00:00:00
abstract:CONCLUSION:This study demonstrated that five Cx26 mutations (R32H, S199F, 572delT, 631-632delGT, and Y155X) affect gap junction (GJ) functions by causing impaired membrane targeting and aberrant cellular localization, and one mutation (R165W) leads to a constriction of the channel pore with no dye coupling. OBJECTIVE:...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489.2010.506885
更新日期:2011-01-01 00:00:00
abstract:CONCLUSION:Although this study did not show higher risk of oropharyngeal malignancy in HIV patients overall, they still had much higher prevalence of NHL as well as HL than HIV negative patients. Presence of cervical lymphadenopathy is unreliable in differentiating malignant oropharyngeal tumours from benign lymphoid h...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489.2016.1170878
更新日期:2016-09-01 00:00:00
abstract::One hundred patients subjected to tonsillectomy because of recurrent acute tonsillitis or tonsillar hypertrophy were evaluated bacteriologically both with ordinary throat culturing and cultures from tonsillar cores. In 26% of the patients H. influenzae was isolated and in 20% beta-haemolytic group A streptococci. Grow...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489009107448
更新日期:1990-03-01 00:00:00
abstract::Sigmoid sinus diverticulum-induced pulsatile tinnitus is a rare medical problem. Here we report a case where pulsatile tinnitus occurred in the perimenopause with evidence of sigmoid sinus diverticulum. The tinnitus disappeared with the restoration of hearing after surgery. While diagnosis is critical for the treatmen...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489.2011.567998
更新日期:2011-08-01 00:00:00
abstract::The submucosal glands in the rat nose are characterized by the presence of both neutral and acid glycoproteins, which are important constituents of nasal and tracheobronchial secretions. This study is an attempt to gain a better insight into the secretion of these two types of glycoproteins and its neural regulation. ...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016488709128287
更新日期:1987-11-01 00:00:00