Abstract:
CONCLUSION:Although this study did not show higher risk of oropharyngeal malignancy in HIV patients overall, they still had much higher prevalence of NHL as well as HL than HIV negative patients. Presence of cervical lymphadenopathy is unreliable in differentiating malignant oropharyngeal tumours from benign lymphoid hyperplasia in HIV patients. OBJECTIVES:The aim of this study was to compare the histology of oropharyngeal masses between HIV positive and negative patients. METHODS:A retrospective review of 119 patients who underwent oropharyngeal biopsies in a tertiary institution between 2007-2014 and whose HIV status was known (HIV positives =47; negatives =72). RESULTS:Malignancies occurred in 63.8% of HIV patients and 65% of the negative group (p = 0.87). While non-Hodgkin's lymphoma (NHL), squamous cell carcinoma (SCC), and Hodgkin's lymphoma (HL) constituted 40%, 27%, and 17% of malignancies in HIV patients, respectively; in the HIV-negative group, it was 53%, 13%, and 2% for SCC, NHL, and HL, respectively (p = 0.039, 0.017, and 0.035, respectively). Reactive lymphoid proliferation accounted for 82.4% of the benign masses in the HIV positive group. Malignant tumours were recorded more in younger patient in the HIV positive than the negative group (p = 0.001).
journal_name
Acta Otolaryngoljournal_title
Acta oto-laryngologicaauthors
Alex-Okoro J,Orji FT,Umedum NG,Akpeh JOdoi
10.3109/00016489.2016.1170878subject
Has Abstractpub_date
2016-09-01 00:00:00pages
969-72issue
9eissn
0001-6489issn
1651-2251journal_volume
136pub_type
杂志文章abstract::The effect of adaptation of the ear on the SISI test was studied at 500 Hz and 2000 Hz in 43 patients with chronic otitis and in 20 patients with otosclerosis. The mean adaptation was slightly over 10 dB, except in the otosclerosis group at 2000 Hz, for which the value was nearly 20 dB after continuous stimulation at ...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016487509121302
更新日期:1975-07-01 00:00:00
abstract::Synthesis of prostaglandins (PGs) was characterized in the lateral wall (LW) of guinea-pig cochlea. Basal synthesis at 37 degrees C was about 480 pg/LW (12.8 ng X mg-1 protein) for PGI2 and 85 pg/LW (2.3 ng X mg-1 protein) for PGE2, levelling out after 10 min of incubation. Incubation with arachidonic acid (10(-5) M) ...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:
更新日期:1987-05-01 00:00:00
abstract::The author has performed clinical and follow-up studies of 80 acromegalic patients treated by transanthro-sphenoidal removal of the pituitary adenoma. Heredity for acromegaly or gigantism was recorded in 3.8% of the patients and other hereditary factors in 13.8%. Head trauma, meningitis or encephalitis was recorded in...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016487609120891
更新日期:1976-09-01 00:00:00
abstract::From a study of nitric oxide (NO) output in the nose and sinuses it seems that: (i) the results obtained regarding the regulation of NO output in the nose do not necessarily apply to the sinuses; (ii) the results obtained for one group of sinuses may not apply to another; and (iii) NO output in the sinuses does not be...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016480510031524
更新日期:2005-10-01 00:00:00
abstract::Malignant laryngeal tumours with spindle-cell morphology are relatively rare. Differential diagnosis of spindle-cell carcinoma, leiomyosarcoma, fibrosarcoma, rhabdomyosarcoma, malignant melanoma and inflammatory myofibroblastic tumour may be particularly difficult. Ambiguous and indeterminate diagnoses are also possib...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/0036554021000028070
更新日期:2003-01-01 00:00:00
abstract:CONCLUSION:Because nystagmus induced by ampullopetal inhibition of the posterior semicircular canal (PSCC) rotates around the axis perpendicular to the plane of the anterior semicircular canal (ASCC) of the other side, when free-floating debris is initially located at the distal portion of the PSCC, a patient showing p...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489.2012.763180
更新日期:2013-06-01 00:00:00
abstract:CONCLUSION:Neck dissection (ND) may not be warranted for those patients with complete response in the neck. Human papillomavirus (HPV)-positive or -negative tumour does not affect this recommendation. OBJECTIVES:Treatment of tonsillar cancer varies considerably worldwide, although non-surgical treatment, e.g. radiothe...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489.2014.920516
更新日期:2014-10-01 00:00:00
abstract::The MRL/lpr mouse, which is homozygous for the recessive lpr genes and has a mutation in the Fas gene encoding a cell-surface receptor for apoptosis, exhibits severe lymphadenopathy and develops systemic lupus erythematosus (SLE)-like disease. It has recently been reported that this mouse also manifests sensorineural ...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016480310015344
更新日期:2004-01-01 00:00:00
abstract::Luetic hydrops can occur in both congenital and acquired lues and otologic manifestations may be indistinguishable from Meniere's disease. Eight endolymphatic sac decompression procedures were performed on 6 patients with refractory luetic vertigo. Of those, 3 had congenital and 3 acquired lues. All cases had received...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016488009127172
更新日期:1980-05-01 00:00:00
abstract:OBJECTIVE:To improve the efficacy of intratympanic therapy using perilymphatic entry through the round window membrane. MATERIAL AND METHODS:The perilymphatic entry characteristics of 2 neutral molecules, mannitol (182.2 Da) and inulin (7,000 Da), were studied. A polyethylene catheter was placed in contact with the gu...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016480310001042
更新日期:2003-01-01 00:00:00
abstract::A case-control design was used to assess eye-head-trunk coordination for community-dwelling elders performing a stand-walk task. Eighteen elders with a high risk of falling were matched to 18 subjects with low risk on the basis of age, living status (living alone or with someone) and category of residence (independent...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016480152583656
更新日期:2001-09-01 00:00:00
abstract:CONCLUSION:The average recovery of hearing and cessation of tinnitus was significantly better after treatment with Radix Astragali (RA) than after non-treatment with RA. RA can be valuable adjuvant therapy for patients with acute acoustic trauma (AAT). OBJECTIVES:AAT is one of the early indications for the use of RA. ...
journal_title:Acta oto-laryngologica
pub_type: 临床试验,杂志文章
doi:10.3109/00016489.2011.591823
更新日期:2011-10-01 00:00:00
abstract:CONCLUSIONS:The present study revealed that miR-21 promotes the proliferation and invasion of cholesteatoma keratinocytes. These results provide a partial explanation for the more aggressive clinical behavior observed in cholesteatoma. OBJECTIVE:This study aims to investigate the post-transcriptional regulatory effect...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016489.2016.1202447
更新日期:2016-12-01 00:00:00
abstract::One hundred and fifty-five patients with complaints indicating acute sinusitis were examined and their symptoms and signs registered. The final diagnosis--maxillary sinus empyema versus not empyema--was established by means of antral aspiration. A computer-based analysis of clinical data demonstrated the significance ...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016488809097017
更新日期:1988-03-01 00:00:00
abstract::Nl action potentials, elicited by low-level, 4.0-kHz filtered clicks, were recorded from the ear canals of normal-hearing adults. Responses were recorded at two sensation levels in the presence and absence of a pure tone delivered to the contralateral ear. Waveforms were analysed for changes in amplitude and latency. ...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016488709107792
更新日期:1987-05-01 00:00:00
abstract::45CaCl2 was injected into gerbils in single or multiple doses, and the resulting radioactivity in serum, otoconial CaCO3, bone samples, and selected labyrinthine epithelium was determined by liquid scintillation spectrometry. Incorporation into both utricular and saccular otoconia occurred at the rate of 0.06-0.07 nmo...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016487509121327
更新日期:1975-09-01 00:00:00
abstract:CONCLUSION:In the present study, about one-third of patients with Meniere's disease developed benign paroxysmal positional vertigo (BPPV)-like attacks. Additionally, more than one-third of all vertigo attacks were BPPV-like attacks. Thus, vertigo attacks in patients with Meniere's disease must be carefully treated beca...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489.2014.936624
更新日期:2014-11-01 00:00:00
abstract:CONCLUSION:A new murine model for the study of Ménière's disease has been developed by treatment with both lipopolysaccharide (LPS) and aldosterone. Induction of vestibular dysfunction in the hydropic animal model may entail additional stress such as reduced inner ear blood flow, and sudden acute changes in endolymph v...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016480701497436
更新日期:2008-03-01 00:00:00
abstract::This study was designed to investigate properties of laryngeal secretion and secretory activity of IgA in the larynx. Laryngeal secretions were collected by adsorption method on filter paper during laryngomicrosurgery from 20 patients having an inflammatory lesion in the larynx. Contents of IgG, IgA, IgE, secretory co...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016487909126397
更新日期:1979-01-01 00:00:00
abstract::Histological measures of cochlear vasculature and blood flow were examined in 20 guinea pigs. Sixteen were exposed to octave band noise at 120 dB SPL for 30 min and then permitted to survive after the exposure for 6 h, 18 h, 48 h, or 4 weeks (N = 4 in each group). Control animals were exposed to the laboratory and app...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016488509108582
更新日期:1985-07-01 00:00:00
abstract:CONCLUSION:Low-dose administration of Aspartame (Ap) did not produce a significant ototoxic effect at the end of the 6th month. However, duration of the ototoxic effect is shortened and severity of the effect is increased as dose and duration of Ap administration is increased. OBJECTIVES:While Ap toxicity has been stu...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016489.2016.1256498
更新日期:2017-04-01 00:00:00
abstract:CONCLUSION:Saccular and utricular maculae can provide information on the supine static position, considering that both have pronounced curved structures with hair cells having a variety of polarization vectors that enable them to sense an inverted position and thus direct the righting reflex. OBJECTIVE:The vestibular ...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016480510036448
更新日期:2005-05-01 00:00:00
abstract:CONCLUSION:The results of this study give support to the theory that opening the middle ear (ME) to the atmosphere leads to a deterioration in its pressure regulation capacity. However, this is probably not the reason why a perforation of the tympanic membrane becomes chronic. OBJECTIVE:Direct, continuous measurement ...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016480510029374
更新日期:2005-07-01 00:00:00
abstract:CONCLUSION:Nuclear expression of survivin should be studied as a promising marker of higher-risk laryngeal basaloid squamous cell carcinomas (BSCCs), which can then be treated more aggressively and followed more closely. OBJECTIVE:BSCC is an uncommon bimorphic variant of SCC. The hypothesized greater aggressiveness an...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016480500266685
更新日期:2006-02-01 00:00:00
abstract:CONCLUSION:Our results indicate that siRNA E6 and/or E7 may have potential as a gene-specific therapy for human papillomavirus (HPV) type 16 (HPV16)-related squamous cell carcinoma of the head and neck (HNSCC). OBJECTIVES:To evaluate the effectiveness of siRNA targeting E6 and/or E7 on the in vitro and in vivo growth ...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489.2013.773405
更新日期:2013-07-01 00:00:00
abstract::Substance P has been proved an important neurotransmitter and neuromodulator, serving not only as an excitatory transmitter of the first afferent synapse of pain pathways but as a valuable neuromodulator in the primary cortical areas of sensosensorial integration. In the human acoustic cortex, substance P has been fou...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016488909127525
更新日期:1989-05-01 00:00:00
abstract:CONCLUSION:The data suggest that histamine up-regulates MUC2 gene regulation and mucin production in airway epithelial cells through histamine 1 receptor (H1R). Histamine appears to play an important role in the early phase of mucin regulation, which might be effectively blocked by an H1R antagonist. OBJECTIVE:Histami...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489.2012.661075
更新日期:2012-06-01 00:00:00
abstract:OBJECTIVE:To develop a large animal model for studies of laryngeal abductor reinnervation. MATERIAL AND METHODS:Six minipigs underwent unilateral anastomosis of the phrenic nerve-abductor branch of the recurrent laryngeal nerve (RLN). Polyhydroxybutyrate (PHB) conduits were used for repair. At each of 30, 60 and 120 d...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016480410022507
更新日期:2004-09-01 00:00:00
abstract::Life-threatening cervical complications associated with infectious mononucleosis are rare. The combination of acute epiglottitis and subsequent necrotizing fasciitis of the head and neck in a patient with infectious mononucleosis has not been reported to date.A 47-year-old female with infectious mononucleosis and epig...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016480510027475
更新日期:2005-10-01 00:00:00
abstract::The vestibular and optokinetic responses of a group of white cats were evaluated and compared with the responses from a control group of pigmented animals. The results indicate that in all cases the white cats exhibited varying degrees of vestibular and/or optokinetic dysfunction, which in some animals varied from tes...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016487709123944
更新日期:1977-07-01 00:00:00