Abstract:
CONCLUSION:The results of this study give support to the theory that opening the middle ear (ME) to the atmosphere leads to a deterioration in its pressure regulation capacity. However, this is probably not the reason why a perforation of the tympanic membrane becomes chronic. OBJECTIVE:Direct, continuous measurement is a method of studying ME pressure regulation. We found previously that subjects with chronic central perforation (CCP) had a negative ME pressure in the daytime, in contrast to subjects with healthy ears. In this study, in order to elucidate the cause of this negative pressure, measurements were performed in healthy ears with ventilation tubes (VTs). MATERIAL AND METHODS:A VT was inserted 1 week prior to the measurements in 18 subjects. A hearing protector was tightly fitted deep into the external ear canal and connected to a portable system consisting of a pressure transducer and a memory. RESULTS:The measurements revealed a mean ME pressure during the first 3 h of -27 daPa. Ten subjects showed an initial decrease in pressure leading to a considerable negative mean ME pressure and a poor ability to equilibrate pressure differences through the Eustachian tube, like the subjects with CCP.
journal_name
Acta Otolaryngoljournal_title
Acta oto-laryngologicaauthors
Brattmo M,Tideholm B,Carlborg Bdoi
10.1080/00016480510029374subject
Has Abstractpub_date
2005-07-01 00:00:00pages
702-6issue
7eissn
0001-6489issn
1651-2251pii
MDKE25R56AUVKHTXjournal_volume
125pub_type
杂志文章abstract::Glyconjugate expression in formalin-fixed, paraffin-embedded Sjögren's syndrome labial glands (nine cases) was compared with that in normal glands (12 samples) using a wide panel of lectins. Mucous cells expressed mainly mucous-type glycoproteins including sialyl, fucosyl, galactosyl and galactosaminosyl residues, and...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489709114217
更新日期:1997-11-01 00:00:00
abstract:OBJECTIVE:The aim of this double-blind, randomized, multicenter study was to compare the efficacy of betahistine dihydrochloride (BH) and flunarizine (FL) using the Dizziness Handicap Inventory (DHI), a validated self-assessment questionnaire that has not previously been used in a clinical trial to evaluate antivertigo...
journal_title:Acta oto-laryngologica
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
doi:10.1080/00016480310001475
更新日期:2003-06-01 00:00:00
abstract::The aim of this study was to evaluate the effects of argon laser irradiation of the semicircular canals using computed tomography (CT) images and to examine the basis for laser treatment for benign paroxysmal positional vertigo (BPPV). CT images of the posterior canal were evaluated postoperatively in a patient with i...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489.2011.622292
更新日期:2012-01-01 00:00:00
abstract:CONCLUSIONS:Flat-panel cone-beam computed tomography (CBCT) is able to assess the trajectory of the implanted cochlear implant (CI) array. This is essential to determine specific effects of electrode design and surgical innovations on outcomes in cochlear implantation. CBCT is a non-invasive approach yielding similar d...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489.2011.644805
更新日期:2012-04-01 00:00:00
abstract:CONCLUSIONS:Available multichannel cochlear implants (CIs) provide effective tinnitus suppression. More sophisticated speech strategies are more effective than analogue or slow strategies. The mechanisms by which tinnitus is suppressed by CIs are unclear; however, both acoustic masking and reorganization of the right a...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016480701387173
更新日期:2008-02-01 00:00:00
abstract:CONCLUSIONS:The heparin-binding epidermal growth factor-like growth factor (HB-EGF) plays an essential role in the development and invasiveness of cholesteatoma. This study may help to realize the molecular mechanisms underlying the pathogenesis of cholesteatoma and make HB-EGF a promising target for drug intervention ...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016489.2017.1284343
更新日期:2017-08-01 00:00:00
abstract:CONCLUSION:The midline electroneurography (ENoG) method might reflect total facial nerve degeneration. OBJECTIVE:We compared ENoG values in patients with facial palsy using two different methods, the midline method and five electroneurogram recordings, to reveal whether the ENoG value obtained with the midline method ...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489.2012.743680
更新日期:2013-03-01 00:00:00
abstract:CONCLUSIONS:The underlying pathophysiological mechanisms of the posterior nasal nerve (PNN) resection involved the suppression of the secretogogue motor and the inhibition of neurogenic inflammation induced by parasympathetic and sensory denervation. OBJECTIVE:The study was designed to clarify the underlying mechanism...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016480801935525
更新日期:2008-01-01 00:00:00
abstract:CONCLUSIONS:The critical stage for cochlear gene regulation in the embryo is E49-E56. These data provide a valuable resource to help elucidate gene regulation in cochlear development and will benefit ear-related studies, especially those that focus on gene and stem cell therapies in hearing loss. OBJECTIVES:To investi...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016489.2017.1341641
更新日期:2017-11-01 00:00:00
abstract:CONCLUSION:Salivary gland diseases should be handled with a high index of suspicion. Although an inference could be drawn it is not clear from this study if primary head and neck cancers (HNCs) have a significant association with HIV/AIDS. OBJECTIVE:HIV/AIDS manifestations and malignancies do occur in the head and nec...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016480701230936
更新日期:2007-11-01 00:00:00
abstract:OBJECTIVE:To investigate the positive rate for the Cochlin tomo-protein (CTP: an inner ear-specific protein) detection test among patients with inner ear-related clinical manifestations and evaluate the clinical characteristics of definite perilymphatic fistula (PLF). METHODS:We have performed an ELISA-based CTP detec...
journal_title:Acta oto-laryngologica
pub_type: 临床试验,杂志文章,多中心研究
doi:10.1080/00016489.2017.1300940
更新日期:2017-01-01 00:00:00
abstract::The influence of cigarette smoke on the pharyngeal mucosa was investigated in a clinical study and in an experiment on animals. Histologic reports were evaluated according to the Kambic-Lenart classification of hyperplastic aberrations of the throat mucosa. A close dependence of the degree of hyperplasia and the numbe...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016487809121433
更新日期:1978-01-01 00:00:00
abstract::The aim of this paper was to examine the accuracy of passive whole-body self-rotation estimate around the earth-vertical (yaw) axis. Subjects were required to reach an imposed angle of +/- 90 degrees, 180 degrees or 360 degrees (outward way), and then to rotate back to the initial position (return way), through passiv...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489509133338
更新日期:1995-01-01 00:00:00
abstract:CONCLUSIONS:Increased expression of Dicer may be a prognostic biomarker for patients with laryngeal squamous cell carcinoma (LSCC). OBJECTIVES:Recent studies have shown that many microRNAs (miRNAs) play an important role in the development and progression of human cancers. Dicer, one of the most important enzymes of t...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489.2014.920962
更新日期:2014-09-01 00:00:00
abstract::An X-ray energy dispersive analysis was performed on the mature serial sectioned freeze-dried mammalian labyrinth (CBA/CBA mouse). The elemental distribution in the endolymphatic and perilymphatic spaces revealed similar results as have been reported in the literature when withdrawing fluid for microanalysis. The cupu...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016488009131744
更新日期:1980-11-01 00:00:00
abstract::We examined the mucosa of 50 rat middle ears in an experimental model of acute otitis media, in order to obtain information on the mechanisms of polyp formation. The right middle ear of 25 rats was inoculated with type 3 pneumococci, and the left ear served as a control. The animals were killed, the middle ear bulla r...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489509133351
更新日期:1995-01-01 00:00:00
abstract:CONCLUSION:Low-dose administration of Aspartame (Ap) did not produce a significant ototoxic effect at the end of the 6th month. However, duration of the ototoxic effect is shortened and severity of the effect is increased as dose and duration of Ap administration is increased. OBJECTIVES:While Ap toxicity has been stu...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016489.2016.1256498
更新日期:2017-04-01 00:00:00
abstract:CONCLUSION:This study demonstrated differential gene expression profiles in salicylate ototoxicity with oligonucleotide microarray. This study may also provide basic information on candidate genes associated with hearing loss and/or tinnitus or recovery after salicylate-induced cochlear dysfunction. OBJECTIVES:Salicyl...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016480600801365
更新日期:2007-05-01 00:00:00
abstract::Utilizing an enlarged middle cranial fossa approach to the cerebello-pontine angle without destruction of the labyrinth or cochlea the authors have since 1981 operated on 263 unilateral acoustic neurinomas. Tumour sizes ranged between 3 mm intrameatal and 35 mm within the cerebello-pontine angle. Complete tumour remov...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489209137419
更新日期:1992-01-01 00:00:00
abstract::In a previous paper we demonstrated physiologically a sensitive period for acoustic trauma in the rat pup cochlea, with a maximum at 22 days of age. Seven or 60 days after noise exposure these 22-day exposed rats were used for light and electron microscopy. At 7 days, surface preparation revealed restricted damage to ...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016488009127143
更新日期:1980-03-01 00:00:00
abstract::Dose-effect curves for inhibition of growth of P388/P mouse lymphoma cells by ethacrynic acid and kanamycin used alone and in combination were determined in vitro. Ethacrynic acid was 600 times more potent than kanamycin and combinations of the drugs resulted in overall additive effects. These results were compared wi...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016487909126389
更新日期:1979-01-01 00:00:00
abstract:CONCLUSIONS:Thorough otomicroscopical examination of the tympanic membrane in acute otitis media (AOM) might distinguish AOM episodes caused by different bacteria. It thus might be a way to select appropriate treatment for each patient without raising the number of dangerous complications. OBJECTIVES:The aim of this s...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016480601091719
更新日期:2007-09-01 00:00:00
abstract::Smooth pursuit responses to sinusoidal and triangular waveform targets were investigated in elderly and middle-aged subjects. The middle-aged pursued triangular targets with significantly lower gain than sinusoidal targets. In the elderly, pursuit gain was significantly lower than in the middle-aged under all target c...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016488709107331
更新日期:1987-09-01 00:00:00
abstract:CONCLUSION:Computed tomography (CT) in nasal polyposis (NP) patients has three functions before any treatment. CT provides objective evidence of the disease and precise topography of the disease, and is an indicator of the disease severity. After functional endoscopic sinus surgery (FESS), CT is an indicator of the res...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016480701551760
更新日期:2008-03-01 00:00:00
abstract:OBJECTIVE:To determine the clinical usefulness of the dichotic multiple-frequency (MF) auditory steady-state response (ASSR) technique for estimating normal hearing compared to a 0.5-kHz tone burst and broadband click auditory brainstem response (ABR) protocol in a sample of adults. MATERIAL AND METHODS:A comparative ...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016480310015902
更新日期:2004-01-01 00:00:00
abstract::Phoniatric and acoustic examinations were carried out in a group of 30 patients with dysphonia, including 15 with organic type and 15 with functional type. A complex phoniatric assessment offered the possibility to differentiate between these two groups of pathological voices. This was achieved also on the basis of ac...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489109137412
更新日期:1991-01-01 00:00:00
abstract::Formation of carotid artery pseudoaneurysm is uncommon after intensive treatment for head and neck cancer. We encountered a case of postoperative formation of pseudoaneurysm at the left carotid bifurcation in a diabetic man. The risk factors for carotid artery pseudoaneurysm in the patient included diabetes mellitus, ...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016480500437401
更新日期:2006-05-01 00:00:00
abstract::In a double-blind crossover trial, 24 patients with perennial rhinitis have been treated with 2% disodium cromoglycate (DSCG) nasal spray. 15 patients preferred DSCG to placebo, 9 patients showed no preference. Analysis of the diary cards showed a significant preference of DSCG in the group which received placebo firs...
journal_title:Acta oto-laryngologica
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.3109/00016487709123969
更新日期:1977-09-01 00:00:00
abstract:CONCLUSION:The results suggested mercury (Hg)-induced anomalies in the brainstem-mediated acoustic stapedius muscle reflex in children. OBJECTIVES:Hg exposure has been associated with hearing impairment and brainstem anomalies. Acoustic stapedius reflex (ASR) thresholds, growth functions, decay/adaptation times, and b...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489.2011.617778
更新日期:2012-01-01 00:00:00
abstract::T lymphocytes from tonsil (To) and peripheral blood (PB) of 4 tonsillectomized children were subjected to clonal expansion with PHA in order to analyze at single cell level their cytolytic activity and their ability to produce interleukins such as IL-2, IFN-gamma and IL-4. Analyzing all T-cell clones (CD4+ and CD8+) o...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489109138439
更新日期:1991-01-01 00:00:00