Differential gene expression profiles in salicylate ototoxicity of the mouse.

abstract：:The gas nitric oxide (NO) is present in high concentrations in human nasal airways. Since NO is known to inhibit the growth of bacteria and viruses, it has been suggested that airborne NO represents the first line of defence against pathogens in the upper airways. Low nasal NO levels have been reported previously in p...

journal_title：Acta oto-laryngologica

authors： Palm J,Lidman C,Graf P,Alving K,Lundberg J

更新日期：2000-03-01 00:00:00

abstract：:Cochlear blood flow is considered to be closely related to cochlear function. Among several etiologic factors implicated in inner ear diseases, disturbance of local blood flow is held to be one of the most important. With this in view, various pharmaceuticals are currently being used to increase local blood flow in pa...

journal_title：Acta oto-laryngologica

authors： Kawakami M,Makimoto K,Yamamoto H,Takahashi H

更新日期：1992-11-01 00:00:00

abstract：:The aerobic and anaerobic bacterial flora of middle ear exudate (MEE) of 47 consecutive patients with chronic suppurative otitis media were studied using a quantitative bacteriological technique under strictly anaerobic conditions. Specimens from the external auditory canal (EAC) and the nasopharynx (NP) were obtained...

journal_title：Acta oto-laryngologica

authors： Jonsson L,Schwan A,Thomander L,Fabian P

更新日期：1986-11-01 00:00:00

abstract：:Nine subjects with long-term (8-30 years) occupational exposure to industrial solvents and a confirmed diagnosis of psycho-organic syndrome (POS) have been studied with audiological and otoneurological test batteries. The results were compared to a matched control group of nine industrial workers not exposed to solven...

journal_title：Acta oto-laryngologica

authors： Möller C,Odkvist LM,Thell J,Larsby B,Hydén D,Bergholtz LM,Tham R

更新日期：1989-01-01 00:00:00

abstract：:Morphology of the tympanic membrane (TM) and external auditory canal (EAC) was studied in healthy, intact rat ears. TM-perforated ears (3 days after making the perforation) and TM-perforation-healed ears (14, 28 and 42 days after making the perforation). In intact ears, the epidermis in the annular region of the EAC d...

journal_title：Acta oto-laryngologica

authors： Kakoi H,Anniko M

更新日期：1996-11-01 00:00:00

abstract：:The inner ear of mutant bustling mice, BUS/Idr, was examined histopathologically. LM examinations revealed an age-dependent degeneration of the auditory organ of Corti in BUS homozygotes, but not heterozygotes. Cochlear base-to-apex gradient in severity of the degeneration was noted. First signs of degeneration were f...

journal_title：Acta oto-laryngologica

authors： Yonezawa S,Nodasaka Y,Kamada T,Fujita SC,Kato K,Yamada Y,Ogasawara N,Shoji R

更新日期：1996-05-01 00:00:00

abstract：CONCLUSIONS:The vestibular function can be assessed by ice-water caloric test, rotational chair test and VEMP recording in severely hearing impaired infants and young children, and 85% of these patients showed abnormal responses in these tests. OBJECTIVES:To evaluate the vestibular function of infants and young childr...

journal_title：Acta oto-laryngologica

authors： Shinjo Y,Jin Y,Kaga K

更新日期：2007-07-01 00:00:00

abstract：CONCLUSION:The Na-K-2Cl cotransporter-1 (NKCCl) may be essential for the maintenance and functioning of the vestibular morphology in mice and it is strongly expressed in human vestibular end organs. OBJECTIVE:NKCCl is a member of the cation-coupled chloride transporter which participates in salt transport and cell vol...

journal_title：Acta oto-laryngologica

authors： Young Choi J,Ho Jung S,Namkung W,Lee JH,Jin Son E,Wook Shin J,Park HY,Sang Lee W,Kim HN

更新日期：2005-12-01 00:00:00

abstract：CONCLUSION:The technology of stimulation rates between 1500 and 5000 pulses per second per channel (pps/ch) brings a benefit for all users. However, the fastest possible rate does not necessarily lead to best hearing performance in each individual subject. Individual optimization of stimulation rate is recommended. OB...

journal_title：Acta oto-laryngologica

authors： Buechner A,Frohne-Büchner C,Gaertner L,Stoever T,Battmer RD,Lenarz T

更新日期：2010-01-01 00:00:00

abstract：:Thirteen normal subjects were investigated with a broad frequency-band (up to 4.5 Hz) rotatory test. The vestibular stimulation consisted of either a pseudo-random or a sinusoidal frequency sweep oscillation. Eye movements were recorded by EOG. Head movements were recorded either by a potentiometer attached to the cha...

journal_title：Acta oto-laryngologica

authors： Larsby B,Hydén D,Odkvist LM

更新日期：1984-03-01 00:00:00

abstract：:We studied the influence of neck afferents on the perception of orientation. In Experiment 1, we investigated the effect of head tilt on the subjective vertical in both the visual and tactile modalities. The results showed that head tilt triggers an Aubert effect in the visual modality and a Müller effect in the tacti...

journal_title：Acta oto-laryngologica

authors： Guerraz M,Luyat M,Poquin D,Ohlmann T

更新日期：2000-09-01 00:00:00

abstract：CONCLUSION:The visual outcomes of endoscopic treatment of optic neuropathy are favorable. However, no specific prognostic factor was associated with good outcome. OBJECTIVE:To investigate visual outcomes of patients with optic neuropathy caused by paranasal mucocele or sinusitis. METHODS:The clinical course in 38 pat...

journal_title：Acta oto-laryngologica

authors： Nakaya K,Oshima T,Kudo T,Ikeda R,Hidaka H,Kobayashi T

更新日期：2011-08-01 00:00:00

abstract：:The blowing of chilled (14 degrees C) air into the external auditory canal (EAC) resulted in a profuse middle ear fluid production. The stimulation caused marked changes in the pars flaccida of the tympanic membrane. A slight vasodilatation was noted in the oedematous loose connective tissue layer of the pars flaccida...

journal_title：Acta oto-laryngologica

authors： Goldie P,Hellström S

更新日期：1986-09-01 00:00:00

abstract：:Luetic hydrops can occur in both congenital and acquired lues and otologic manifestations may be indistinguishable from Meniere's disease. Eight endolymphatic sac decompression procedures were performed on 6 patients with refractory luetic vertigo. Of those, 3 had congenital and 3 acquired lues. All cases had received...

journal_title：Acta oto-laryngologica

authors： Paparella MM,Kim CS,Shea DA

更新日期：1980-05-01 00:00:00

abstract：:Although still the subject of discussion, vestibular-evoked myogenic potentials (VEMPs) have been considered to reflect the function of the saccular and, more recently, the cochlear tracts. To accurately determine the precise afferent pathway carrying VEMPs, we studied the outcomes of VEMPs and other examinations in p...

journal_title：Acta oto-laryngologica

authors： Tsutsumi T,Komatsuzaki A,Noguchi Y,Tokano H,Kitamura K

更新日期：2001-06-01 00:00:00

abstract：:The nasopharyngeal microflora was monitored during a prospective study of 52 otitis-prone children and 33 age-matched controls up to the age of 30 months. The relation between nasopharyngeal culture results and corresponding otoscopic findings was investigated. In contrast to pneumococci, the rate of H. influenzae iso...

journal_title：Acta oto-laryngologica

authors： Freijd A,Bygdeman S,Rynnel-Dagöö B

更新日期：1984-01-01 00:00:00

abstract：:The waltzing guinea pig exhibits genetically induced inner ear disease which develops into deafness and vestibular disorder. The type I hair cell in vestibular end organs shows specific pathology, featuring protrusion of the hair cell apex, sensory hair fusion and an intracellular actin filament rod. With the freeze-f...

journal_title：Acta oto-laryngologica

authors： Sobin A,Flock A,Bagger-Sjöbäck D

更新日期：1983-09-01 00:00:00

abstract：:The embryonic development of the crista ampullaris of the CBA/CBA mouse was followed both in organ culture of explanted inner ears of the 16th gestational day and in vivo from the 16th gestational day until the 21st day, an age corresponding to birth. Cytodifferentiation of the sensory epithelium of the crista ampulla...

journal_title：Acta oto-laryngologica

authors： Nordemar H

更新日期：1983-07-01 00:00:00

abstract：CONCLUSIONS:Intra-arterial high-dose cisplatin chemoradiation (CRT-IA) with sodium thiosulfate (STS) causes relatively less severe cisplatin ototoxicity than intravenous cisplatin chemoradiation without STS (CRT-IV). The results of this study also suggest that early detection of ototoxicity is possible by testing the h...

journal_title：Acta oto-laryngologica

authors： Ishikawa E,Sugimoto H,Hatano M,Nakanishi Y,Tsuji A,Endo K,Kondo S,Wakisaka N,Murono S,Ito M,Yoshizaki T

更新日期：2015-09-01 00:00:00

abstract：:In precollicular decerebrate cats, activation of limb extensors during side-down roll tilt of the animal depends on both an increased discharge of excitatory vestibulospinal neurons and a reduced discharge of inhibitory medullary reticulospinal (mRS) neurons. These inhibitory neurons are tonically excited by a choline...

journal_title：Acta oto-laryngologica

authors： Pompeiano O,Stampacchia G,Horn E,d'Ascanio P

更新日期：1987-05-01 00:00:00

abstract：CONCLUSIONS:Auricle reconstruction combined with hearing reconstruction can help patients with microtia to obtain practical hearing improvement as well as cosmetic improvement. The integrated procedures can facilitate the incision design and obtain a natural-looking three-dimensional shape of the reconstruction auricle...

journal_title：Acta oto-laryngologica

authors： Zhao S,Wang D,Han D,Gong S,Ma X,Li Y,Chen S

更新日期：2012-08-01 00:00:00

abstract：OBJECTIVE:To determine the role of cell proliferation neoplastic progression in the larynx and possibly derive criteria of clinical significance using automated quantitative image analysis. MATERIAL AND METHODS:In a retrospective study involving archival material, the occurrence and location, size, shape and staining ...

journal_title：Acta oto-laryngologica

authors： Laitakari J,Harrison D,Stenbäck F

更新日期：2003-08-01 00:00:00

abstract：:A new generation of cochlear implant electrodes has been designed to position the stimulating contacts close to the modiolus in order to reduce power consumption and increase stimulation selectivity. The purpose of this study was to assess electrode position in the cochlea for three recently designed electrodes. Fifte...

journal_title：Acta oto-laryngologica

authors： Balkany TJ,Eshraghi AA,Yang N

更新日期：2002-06-01 00:00:00

abstract：:The diagnosis and management of spontaneous otogenic pneumocephalus with literature review is described. A young sportsman experienced headache and fluctuating mass in his occiput during increased physical activity. A large extradural intracranial pneumocephalus with corresponding emphysema was imaged on a CT scan. Tr...

journal_title：Acta oto-laryngologica

authors： Mohammed el R,Profant M

更新日期：2011-06-01 00:00:00

abstract：:We recently reported the development of a cell line, AMC-HN-9, established from an undifferentiated carcinoma (UDC) of the parotid gland. AMC-HN-9 consists mostly of spindle-shaped cells, has poor in vitro adhesiveness and an in vitro appearance that is different from that of other epithelial cell lines. To test the h...

journal_title：Acta oto-laryngologica

authors： Kim SH,Carey TE,Liebert M,Yoo SJ,Kwon HJ,Kim SY

更新日期：2000-08-01 00:00:00

abstract：:Critical bandwidths and absolute intensity thresholds were measured in cats before and after kanamycin treatment which induced selective inner and outer hair cell losses. Hair cell losses were measured from cochleograms constructed from surface preparations of the organ of Corti. Results suggested that, for the test f...

journal_title：Acta oto-laryngologica

authors： Nienhuys TG,Clark GM

更新日期：1979-01-01 00:00:00

abstract：:The objective of this study was to determine whether methylcobalamin inhibits the ototoxic action of gentamicin. Fourteen pigmented guinea pigs were randomly divided into experimental and control groups. Each animal in the experimental group was given a large single dose of gentamicin (125 mg/kg i.m.), followed by imm...

journal_title：Acta oto-laryngologica

authors： Jin X,Jin X,Sheng X

更新日期：2001-04-01 00:00:00

abstract：:Anaesthesia and sedation in electrocochleo-graphy are of paramount importance for the whole procedure, since restlessness of the patient during the measurements can invalidate the results of the test. The time needed for extensive electrocochleography amounts on average to two hours. The only pain experienced during t...

journal_title：Acta oto-laryngologica

authors： Zvonar M,Zvonar-Kuhndl B,Odenthal DW

更新日期：1974-01-01 00:00:00

abstract：:During the last third of the 20th century, pediatric otolaryngology became a defined specialty in many nations, resulting in focused training, fellowships, societies, journals, textbooks, etc. This development occurred as a result of an interaction between the changing sociological and economic status of the child and...

journal_title：Acta oto-laryngologica

authors： Ruben RJ

更新日期：2004-05-01 00:00:00

abstract：:Under constant visual guidance and closed-circuit television monitoring, electrodes are inserted into the fluid spaces of the organ of Corti. The resting electrical potentials are determined with respect to the neutral voltage of the guinea pig and related to other potentials of the auditory labyrinth. The resting pot...

journal_title：Acta oto-laryngologica

authors： Lawrence M

更新日期：1975-03-01 00:00:00