Abstract:
:Morphology of the tympanic membrane (TM) and external auditory canal (EAC) was studied in healthy, intact rat ears. TM-perforated ears (3 days after making the perforation) and TM-perforation-healed ears (14, 28 and 42 days after making the perforation). In intact ears, the epidermis in the annular region of the EAC displayed a characteristic appearance with cytoplasmic protrusions. We termed these protrusions as "finger-like projections". In contrast to the rat, the annular region of the EAC in the guinea-pig did not show "finger-like projections". Following a perforation in the centre of the anterior or the posterior quadrant of the pars tensa in rats the "finger-like projections" disappeared from the annular region on the perforated side of the EAC, while the projections remained on the malleus side of the perforation edge. In perforation-healed ears analysed 42 days after the perforation, the "finger-like projections" had recurred in the annular region on the perforated side of the EAC. The "finger-like projections" are likely to express maturation (keratinization) and desquamation of epidermal cells in the pars tensa and also could constitute morphological evidence of their migration on the TM.
journal_name
Acta Otolaryngoljournal_title
Acta oto-laryngologicaauthors
Kakoi H,Anniko Mdoi
10.3109/00016489609137939subject
Has Abstractpub_date
1996-11-01 00:00:00pages
850-3issue
6eissn
0001-6489issn
1651-2251journal_volume
116pub_type
杂志文章abstract::Acid base balance changes were observed during 72 h following bilateral nasal obstruction in rats. Mouth breathing caused acute respiratory acidosis and marked aerophagia, leading to spontaneous death of the experimental animal 80 to 90 h postoperatively. Stenotic oropharyngeal airway, due to palatal-epiglottic approx...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489109137406
更新日期:1991-01-01 00:00:00
abstract:CONCLUSION:This study demonstrated that five Cx26 mutations (R32H, S199F, 572delT, 631-632delGT, and Y155X) affect gap junction (GJ) functions by causing impaired membrane targeting and aberrant cellular localization, and one mutation (R165W) leads to a constriction of the channel pore with no dye coupling. OBJECTIVE:...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489.2010.506885
更新日期:2011-01-01 00:00:00
abstract::A homozygous mutant rat at the white spotting (Ws) locus showing a deficiency of melanocytes has recently been found (4, 5). The function and morphology of the inner ear of the Ws/Ws rat were examined by auditory brainstem response (ABR), endocochlear DC potential (EP), and electron microscopy. The mean ABR threshold ...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489409126038
更新日期:1994-03-01 00:00:00
abstract::The nystagmus and motion perception of two astronauts were recorded during Earth-vertical axis rotation and during off-vertical axis rotation (OVAR) before and after 7 days of spaceflight. Postflight, the peak velocity and duration of per- and postrotatory nystagmus during velocity steps about the Earth-vertical axis ...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489509139374
更新日期:1995-09-01 00:00:00
abstract::The effects of transdermally administered scopolamine (TTS-scopolamine) (release rate 5 micrograms/h, one and two patches) and dimenhydrinate (100 mg) on caloric, angular acceleration induced and optokinetic nystagmus were examined in 16 volunteers in a randomized double-blind study. All drugs induced a statistically ...
journal_title:Acta oto-laryngologica
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.3109/00016488509182266
更新日期:1985-05-01 00:00:00
abstract::We examined the serial changes of intravenously applied dye leakage and preliminary examined histamine release into nasal lavage fluid after topical stimulation with capsaicin in guinea pigs. A significant increase in the dye leakage response was detected for 30-40 min, with the maximum response occurring between 5 an...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489209137438
更新日期:1992-01-01 00:00:00
abstract:CONCLUSION:Chances of hearing preservation are better in patients with vestibular schwannoma (VS) from the superior vestibular nerve (SVN) than from the inferior vestibular nerve (IVN). Pathologic posturography and electronystagmography (ENG) findings are more common in schwannomas from the SVN compared with tumors fro...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489.2010.536991
更新日期:2011-05-01 00:00:00
abstract::In electrocochleography (ECochG) compound action potential (CAP) and summation potential (SP) are usually separated from the cochlear microphonic (CM) by the CM cancellation technique consisting in averaging the responses evoked by rarefaction and condensation clicks. With the aim of analysing the ECochG responses evo...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/000164800750000892
更新日期:2000-03-01 00:00:00
abstract::The muscle fiber content of the stapedius muscle of the cat was determined histochemically using a combination of oxidative enzymes and glycolytic markers. The major fiber type present was determined to be the fast oxidative glycolytic type (FOG; 77%). Two other types of fiber were found that could not be placed into ...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016488209128894
更新日期:1982-07-01 00:00:00
abstract::Fifteen normal speakers (7 women and 8 men), ranging in age from 21 to 35 years, were examined consecutively with rigid telescopy and flexible fiberscopy during sustained phonation at 3 loudness levels. The endoscopes were connected to a stroboscope and video equipment. The purpose was to investigate whether the two l...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489209100796
更新日期:1992-01-01 00:00:00
abstract::In 82 patients with acute tonsillitis studied, beta-hemolytic group A streptococci were isolated from 30 (37%), and group C or G streptococci from 12 (15%). In the 40 patients with non-streptococcal tonsillitis there was a significantly higher isolation rate of pneumococci, H. influenzae and/or B. catarrhalis, as comp...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016488709107339
更新日期:1987-09-01 00:00:00
abstract:CONCLUSIONS:Endoscopic laser microsurgery (ELM) provides comparable oncological outcomes, and improved functional recovery and laryngeal preservation compared with open partial laryngopharyngectomy (OPLP) in patients with early squamous cell carcinoma of the hypopharynx (HPSCC). The use of open surgery is declining. Th...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489.2013.805341
更新日期:2013-10-01 00:00:00
abstract::Background: Lermoyez syndrome (LS) is a rare auditory disorder, the details of LS remain unclear.Objectives: To investigate the grades of endolymphatic hydrops (ELH) and clinical characteristics of clinically diagnosed LS.Material and methods: Nine patients with clinically diagnosed LS were included. three-dimensional...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016489.2020.1751275
更新日期:2020-07-01 00:00:00
abstract:CONCLUSION:A 20 mm hole made backwards from the midpoint of the asterion to the mastoid process is suitable for a retrosigmoid keyhole approach with the aid of an endoscope. The endoscope-assisted retrosigmoid keyhole approach can be considered an effective and safe method for removal of vestibular schwannoma. OBJECTI...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489.2013.817682
更新日期:2013-11-01 00:00:00
abstract::Dose-effect curves for inhibition of growth of P388/P mouse lymphoma cells by ethacrynic acid and kanamycin used alone and in combination were determined in vitro. Ethacrynic acid was 600 times more potent than kanamycin and combinations of the drugs resulted in overall additive effects. These results were compared wi...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016487909126389
更新日期:1979-01-01 00:00:00
abstract:CONCLUSION:Di-K19Hc is a promising new ototopical antibiotic for treatment of middle ear infections associated with antibiotic-resistant bacteria. OBJECTIVES:Di-K19Hc was previously shown to exert profound antimicrobial activity against a variety of antibiotic-resistant bacteria and fungi. In this study, we evaluated ...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016480903536036
更新日期:2010-08-01 00:00:00
abstract:OBJECTIVE:We used ocular vestibular evoked myogenic potentials to investigate the relationship between residual dizziness and utricular function following the canalith repositioning procedure for benign paroxysmal positional vertigo. METHODS:Ocular vestibular evoked myogenic potentials were measured in 44 patients (40...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016489.2017.1347824
更新日期:2017-11-01 00:00:00
abstract:CONCLUSION:Saccular and utricular maculae can provide information on the supine static position, considering that both have pronounced curved structures with hair cells having a variety of polarization vectors that enable them to sense an inverted position and thus direct the righting reflex. OBJECTIVE:The vestibular ...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016480510036448
更新日期:2005-05-01 00:00:00
abstract:CONCLUSION:After conventional curette adenoidectomy, a significant mass of residual adenoid tissue is observed in about 50% of the cases. The combined approach of conventional curette and endoscopic adenoidectomy with microdebrider assures a complete and accurate removal of the mass. It is an effective and safe method ...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016480802294377
更新日期:2009-05-01 00:00:00
abstract:OBJECTIVE:In order to facilitate surgery for spasmodic dysphonia, i.e. type 2 thyroplasty, a device was designed to fix the incised edges of the thyroid cartilage firmly. MATERIAL AND METHODS:Various types and sizes of titanium bridge were developed for clinical use. RESULTS:The results of surgery for spasmodic dysph...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016480410016261
更新日期:2004-04-01 00:00:00
abstract::In the guinea pig, the organ of Corti and the spiral ganglion cells were destroyed by administering gentamicin into the inner ear. The antero-ventral cochlear nucleus (AVCN) was studied with electron microscopy 15 and 30 days after treatment. There does not seem to be a specific type of degeneration induced by the dru...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016488609108643
更新日期:1986-07-01 00:00:00
abstract::Urokinase-type plasminogen activator (uPA) is important for matrix degradation and motility of cancer cells. The binding of uPA to its cell surface receptor on cancer cells is essential for effective invasion. A soluble form of urokinase receptor (suPAR) has been described in serum and ascites of ovarian cancer patien...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016489950180342
更新日期:1999-01-01 00:00:00
abstract:CONCLUSIONS:The transconjunctival approach to orbital floor fractures permits excellent exposure of the inferior orbit and provides a good surgical outcome, especially with regard to ocular motility. OBJECTIVE:Surgical access to orbital floor fractures can be accomplished via the transconjunctival approach. The majori...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016480500395757
更新日期:2006-04-01 00:00:00
abstract:CONCLUSION:Extensive bone erosion correlated with a worse prognosis of the squamous cell carcinoma (SCC) of the temporal bone but extensive soft tissue involvement did not correlate with prognosis in this study. Resectability of the tumor seems to be major prognostic factor of temporal bone SCC. OBJECTIVE:Prognostic f...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016480802642096
更新日期:2009-11-01 00:00:00
abstract::In 4 cases of Meniere's disease, E.P., concentrations of Na, K, Cl, and protein, and osmolality were determined in endolymph from the basal coil of the cochlea. In 3 cases, endolymph was found normal in nature as compared with normal animals. In one long-standing (11 years) case, a strial dysfunction was evidenced. In...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016488409132935
更新日期:1984-05-01 00:00:00
abstract::Retropharyngeal haematomas (RPHs) are rare but potentially life-threatening conditions that require a prompt diagnosis. However, the clinical scenario is not always straightforward as their presentation may be insidious, with no specific signs or symptoms. Treatment of RPH is conservative in the majority of cases, wit...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016480410017233
更新日期:2005-04-01 00:00:00
abstract::In a previous paper we demonstrated physiologically a sensitive period for acoustic trauma in the rat pup cochlea, with a maximum at 22 days of age. Seven or 60 days after noise exposure these 22-day exposed rats were used for light and electron microscopy. At 7 days, surface preparation revealed restricted damage to ...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016488009127143
更新日期:1980-03-01 00:00:00
abstract:CONCLUSION:Patients with posterior semicircular canal dehiscence (PSCD) have low frequency conductive hearing loss similar to patients with superior semicircular canal dehiscence (SSCD) secondary to a pathologic third window. OBJECTIVES:PSCD can result in conductive hearing loss, but the magnitude of this hearing loss...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章,评审
doi:10.3109/00016489.2015.1060630
更新日期:2015-01-01 00:00:00
abstract::Cochlear microphonics (CM) were recorded in the guinea pig using differential recording from the first and third cochlear turns as well as by using a 10-electrode array inserted in the scala tympani of the basal turn. The excitation profile as represented by the CM was quantified by amplitude and phase data, and was m...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016487809121465
更新日期:1978-05-01 00:00:00
abstract:CONCLUSION:The external neck brace (ENB) is a new concept in the improvement of peristomal fixation of an automatic stoma valve (ASV), which was evaluated with a new imaging method. The addition of the ENB to the Flexiderm (FLD) and Xtrabase (XB) adhesives significantly reduced absolute mean differences between the spe...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016480903426600
更新日期:2010-07-01 00:00:00