Abstract:
:The influence of cigarette smoke on the pharyngeal mucosa was investigated in a clinical study and in an experiment on animals. Histologic reports were evaluated according to the Kambic-Lenart classification of hyperplastic aberrations of the throat mucosa. A close dependence of the degree of hyperplasia and the number of cigarettes smoked was revealed. The more cigarettes the patients smoked every day, the more evident were changes on the mucosa, more clearly manifested in male than in female smokers. It was observed that the changes related to the hyperplasia atypica were more evident the longer the patients smoked. They were also more intense the younger the smokers were when they started smoking. In the experiment on animals, a number of factors with additionally noxious influence on the pharyngeal mucosa were excluded. A great interdependence was observed between the number of daily inhaled cigaretes and the changes on the pharyngeal mucosa.
journal_name
Acta Otolaryngoljournal_title
Acta oto-laryngologicaauthors
Radsel Z,Kambic Vdoi
10.3109/00016487809121433subject
Has Abstractpub_date
1978-01-01 00:00:00pages
128-34issue
1-2eissn
0001-6489issn
1651-2251journal_volume
85pub_type
杂志文章abstract:CONCLUSION:The Na-K-2Cl cotransporter-1 (NKCCl) may be essential for the maintenance and functioning of the vestibular morphology in mice and it is strongly expressed in human vestibular end organs. OBJECTIVE:NKCCl is a member of the cation-coupled chloride transporter which participates in salt transport and cell vol...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016480510012309
更新日期:2005-12-01 00:00:00
abstract::The present study further assessed the role of the endolymphatic sac (E.S.) in the generation of inner ear immune responses. Guinea pigs underwent unilateral endolymphatic sac obliteration (Rt) and the opposite ears (Lt) served as controls. The animals were then systemi-cally sensitized to KLII and both inner ears wer...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016488709107782
更新日期:1987-05-01 00:00:00
abstract::The postnatal development of lower stations in the auditory pathway was studied in the guinea pig by recording auditory brainstem potentials. At birth, the brainstem responses of young guinea pigs already have thresholds corresponding to those of adult animals. However, the latencies of the individual potentials are s...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016488409130965
更新日期:1984-01-01 00:00:00
abstract::Cochlear blood flow in guinea pigs was assessed using histological assessment of various red blood cell and vessel lumen parameters. Cochlear blood flow was either enhanced by administration of carbogen or inhibited by induced positive airway pressure. The resulting enhancement or reduction of blood flow in the cochle...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016488709109055
更新日期:1987-07-01 00:00:00
abstract::The distribution of fibronectin (FN) in operative specimens of maxillary sinus mucosa from 35 patients with chronic sinusitis was examined immunohistochemically. Mouse monoclonal antibody to human FN was used for the peroxidase-antiperoxidase staining technique. FN was found in most of the serous cells and in some (ab...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489109137365
更新日期:1991-01-01 00:00:00
abstract::Otorrhea of leaked cerebrospinal fluid and meningitis in a 33-year-old male originated from an encephalic herniation into the middle ear following traumatic temporal bone fracture. CT demonstrated a mixed-type fracture consisting of a longitudinal fracture and a posterior oblique fracture of the left temporal bone. Th...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016480510029266
更新日期:2005-08-01 00:00:00
abstract:BACKGROUND:The most crucial clinical problem of Eosinophilic Otitis Media (EOM) is sensorineural hearing loss. A previous report revealed that repeated antigen stimulation of middle ear causes eosinophilic inflammation not only in the middle ear but also in the inner ear. OBJECTIVE:The purpose of the present study was...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016489.2016.1266508
更新日期:2017-05-01 00:00:00
abstract::In previous studies, sinus secretions have been analysed concerning pO2, pCO2 and pH. In this study the energy metabolism in the maxillary sinus mucosa and secretion was studied in 33 New Zealand White rabbits. In freeze-dried samples, glucose and lactate were analysed by enzymatic assays and ATP by HPLC. In the purul...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016488809122271
更新日期:1988-11-01 00:00:00
abstract:BACKGROUND AND OBJECTIVE:The aim of this study was to demonstrate the long-term effectiveness of Expansion Sphincter Pharyngoplasty (ESP) as a standalone surgical treatment of obstructive sleep apnea-hypopnea syndrome (OSAHS) patients through a prospective multi-center study. MATERIAL AND METHODS:A prospective non-com...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章,多中心研究
doi:10.1080/00016489.2018.1533992
更新日期:2019-02-01 00:00:00
abstract::Four groups of guinea pigs received different doses of cis-platinum. SEM and TEM showed a direct relation between the dose and the damage. The first row of OHC is the first one to be damaged. The IHC are more resistant than the OHC. The pattern of destruction is similar to the one produced by the aminoglucoside antibi...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016488509108921
更新日期:1985-03-01 00:00:00
abstract:CONCLUSION:In patients with early glottic squamous cell carcinoma (SCC) submitted to CO2 laser endoscopic resection, local disease recurrence was significantly correlated with the presence of positive additional surgical margins on permanent sections. OBJECTIVES:To evaluate the rate of cancer recurrence in patients wi...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016480500316985
更新日期:2006-03-01 00:00:00
abstract:CONCLUSIONS:A large set of mucin genes is expressed in nasal polyps. The expression pattern is complex and may reflect the wide spectrum of variables involved in polyp formation and progression. Prospective studies including subgroups of nasal polyps and involving substantial numbers of cases in each subgroup will be r...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016480510027538
更新日期:2005-06-01 00:00:00
abstract::Background: The management of patients with tinnitus who receive middle ear surgery has not been established.Aims: The aim of this study is (1) how many patients who receive middle ear surgery have tinnitus and (2) how educational counselling and middle ear surgery is effective with consistent tinnitus.Subjects and me...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016489.2020.1713397
更新日期:2020-04-01 00:00:00
abstract::Localization of elements at the cellular and sub-cellular levels was performed with the energy dispersive X-ray microanalysis technique, using shock-frozen, freeze-dried and araldite-embedded mouse (CBA/CBA) cochleae sectioned dry. Anatomical identification occurred in the STEM (scanning transmission electron microsco...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016488409107585
更新日期:1984-11-01 00:00:00
abstract:CONCLUSION:This study suggests that hyperbilirubinemia in the neonatal rat can impair auditory function and induce peripheral nerve pathology by reducing neurofilament-positive cells in spiral ganglion neurons (SGNs). This finding indicates a potential connection between hyperbilirubinemia and auditory impairment. OBJ...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489.2014.938361
更新日期:2014-11-01 00:00:00
abstract:CONCLUSION:After conventional curette adenoidectomy, a significant mass of residual adenoid tissue is observed in about 50% of the cases. The combined approach of conventional curette and endoscopic adenoidectomy with microdebrider assures a complete and accurate removal of the mass. It is an effective and safe method ...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016480802294377
更新日期:2009-05-01 00:00:00
abstract:CONCLUSION:Early intervention may change the natural course of allergic rhinitis, preventing the progression to asthma. In particular, immunotherapy guarantees remission of local symptoms and valid protection against local and bronchial complications. Symptomatic treatment represents a valid alternative; it is always t...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489.2013.815362
更新日期:2013-11-01 00:00:00
abstract::The occurrence of artifactual morphological changes was investigated in human eighth nerve biopsies and corresponding changes were brought about in biopsies from rats by mechanical handling before fixation. At the very site of compression by a pair of forceps the biopsy stained lighter than in its immediate surroundin...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016488009127111
更新日期:1980-01-01 00:00:00
abstract:CONCLUSION:The narrowing pattern of the upper airway in obstructive sleep apnea patients may be different in sleep as compared with awake. Three different types of obstruction were observed in these subjects during drug-induced sleep. The different obstruction pattern during drug-induced sleep suggests that different s...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016480902780242
更新日期:2009-12-01 00:00:00
abstract:CONCLUSIONS:The facial nerve courses shown by preoperative CT imaging coincide with the surgical findings in most congenital aural atresia cases. CT scanning is critical in evaluation of a patient's candidacy for atresia surgery. OBJECTIVES:To evaluate the diagnostic value of preoperative CT scanning of the facial ner...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016480801953064
更新日期:2008-01-01 00:00:00
abstract::The formation of otoconia in the endolymphatic sac (ES) of the larval newt, Cynops pyrrhogaster, has been studied by light and transmission electron microscopy. Some of the epithelial cells of the ES contain an abundance of swollen vesicles, Golgi complexes, rough endoplasmic reticula and ribosomes at the late larval ...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016489850154694
更新日期:1998-07-01 00:00:00
abstract:CONCLUSION:Salivary stones in the parotid gland that are not amenable to endoscopic extraction can safely be removed by a combined, endoscopic-external approach. OBJECTIVE:Limitations for endoscopic removability of salivary stones from the parotid gland are immobile stones in the deeper salivary duct system. A combine...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489.2014.953204
更新日期:2015-01-01 00:00:00
abstract::The goal of this investigation was to develop a method of surgical removal of the semicircular canals of the rabbit without induction of auditory impairment. Four different surgical techniques were utilized: i) fenestration of the lateral semicircular canal; ii) fibrin glue perfusion of the canal following fenestratio...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489209137490
更新日期:1992-11-01 00:00:00
abstract::The biocompatibility of commercially available polyimides was examined in relation to the sensory and neural structures of the cochlea. Thin films of four different polyimides were prepared as substrates for photolithographically produced scala tympani electrode arrays and implanted in 32 cat cochleae. Following at le...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016488909127474
更新日期:1989-01-01 00:00:00
abstract::An in vivo method for the study of mucociliary activity in the human trachea and bronchi is presented. The method is based on a two-way fibre-optic system whereby reflections of light emitted by one glass-fibre and reflected by the cilia are picked up by a second glass fibre and transmitted to a recording unit. The gl...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489309135885
更新日期:1993-09-01 00:00:00
abstract::Losses (determined by measuring microphonic responses) were essentially identical, regardless of whether produced by admittance of sound into the middle ear via perforations in the tympanic membrane (TM) or in the bulla. With SPLs monitored directly at the TM, losses increased at 12 dB/oct with inverse frequency for f...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016487609119970
更新日期:1976-03-01 00:00:00
abstract::In a previous communication, we demonstrated that the introduction of air into the scala tympani of the cochlea causes a decrease of cochlear potentials; however, the change in endocochlear dc potential (EP) was mild and the decreased cochlear microphonics (CM) and compound action potentials (CAP) were, at least parti...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489309135892
更新日期:1993-11-01 00:00:00
abstract::IL2Rs, in the presence of IL2, mediate activation and proliferation of human normal lymphocytes and modulate functional changes of some human leukocytic malignancies. IL2Rs have been demonstrated also on human neoplastic and fetal non-hematologic cells in vitro, although their functional role has not been described. W...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016489.1992.11665436
更新日期:1992-01-01 00:00:00
abstract::The inner ear responds immunologically to foreign proteins and pathogens introduced into the cochlea. The route of entry of the cells participating in the inner ear inflammatory process is the spiral modiolar vein with its collecting venules. Since this vein is located adjacent to the scala tympani, the end result of ...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章,评审
doi:10.3109/00016489009107455
更新日期:1990-11-01 00:00:00
abstract:CONCLUSION:Ear, nose and throat (ENT) involvement is common in Churg-Strauss syndrome (CSS), usually manifesting as allergic rhinitis and chronic rhinosinusitis with or without polyps. Otolaryngologists may play a pivotal role in making an early diagnosis of this disease. OBJECTIVES:CSS is a systemic vasculitic disord...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016480500437435
更新日期:2006-05-01 00:00:00