The influence of cigarette smoke on the pharyngeal mucosa.

Abstract:

:The influence of cigarette smoke on the pharyngeal mucosa was investigated in a clinical study and in an experiment on animals. Histologic reports were evaluated according to the Kambic-Lenart classification of hyperplastic aberrations of the throat mucosa. A close dependence of the degree of hyperplasia and the number of cigarettes smoked was revealed. The more cigarettes the patients smoked every day, the more evident were changes on the mucosa, more clearly manifested in male than in female smokers. It was observed that the changes related to the hyperplasia atypica were more evident the longer the patients smoked. They were also more intense the younger the smokers were when they started smoking. In the experiment on animals, a number of factors with additionally noxious influence on the pharyngeal mucosa were excluded. A great interdependence was observed between the number of daily inhaled cigaretes and the changes on the pharyngeal mucosa.

journal_name

Acta Otolaryngol

journal_title

Acta oto-laryngologica

authors

Radsel Z,Kambic V

doi

10.3109/00016487809121433

subject

Has Abstract

pub_date

1978-01-01 00:00:00

pages

128-34

issue

1-2

eissn

0001-6489

issn

1651-2251

journal_volume

85

pub_type

杂志文章
  • Vestibular malformation in mice lacking Na-K-2Cl cotransporter 1 and expression of Na-K-2Cl cotransporter 1 in human vestibular end organs.

    abstract:CONCLUSION:The Na-K-2Cl cotransporter-1 (NKCCl) may be essential for the maintenance and functioning of the vestibular morphology in mice and it is strongly expressed in human vestibular end organs. OBJECTIVE:NKCCl is a member of the cation-coupled chloride transporter which participates in salt transport and cell vol...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.1080/00016480510012309

    authors: Young Choi J,Ho Jung S,Namkung W,Lee JH,Jin Son E,Wook Shin J,Park HY,Sang Lee W,Kim HN

    更新日期:2005-12-01 00:00:00

  • The role of the endolymphatic sac in inner ear immunity.

    abstract::The present study further assessed the role of the endolymphatic sac (E.S.) in the generation of inner ear immune responses. Guinea pigs underwent unilateral endolymphatic sac obliteration (Rt) and the opposite ears (Lt) served as controls. The animals were then systemi-cally sensitized to KLII and both inner ears wer...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.3109/00016488709107782

    authors: Tomiyama S,Harris JP

    更新日期:1987-05-01 00:00:00

  • Postnatal development of the auditory evoked brainstem potentials in the guinea pig.

    abstract::The postnatal development of lower stations in the auditory pathway was studied in the guinea pig by recording auditory brainstem potentials. At birth, the brainstem responses of young guinea pigs already have thresholds corresponding to those of adult animals. However, the latencies of the individual potentials are s...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.3109/00016488409130965

    authors: Dum N

    更新日期:1984-01-01 00:00:00

  • Histological measures of cochlear blood flow. A validation study.

    abstract::Cochlear blood flow in guinea pigs was assessed using histological assessment of various red blood cell and vessel lumen parameters. Cochlear blood flow was either enhanced by administration of carbogen or inhibited by induced positive airway pressure. The resulting enhancement or reduction of blood flow in the cochle...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.3109/00016488709109055

    authors: Dengerink HA,Axelsson A,Wright J,Miller J

    更新日期:1987-07-01 00:00:00

  • Immunohistochemical distribution of fibronectin in the mucosa with chronic sinusitis.

    abstract::The distribution of fibronectin (FN) in operative specimens of maxillary sinus mucosa from 35 patients with chronic sinusitis was examined immunohistochemically. Mouse monoclonal antibody to human FN was used for the peroxidase-antiperoxidase staining technique. FN was found in most of the serous cells and in some (ab...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.3109/00016489109137365

    authors: Ito O,Suzaki H,Nomura Y

    更新日期:1991-01-01 00:00:00

  • Brain herniation into the middle ear following temporal bone fracture.

    abstract::Otorrhea of leaked cerebrospinal fluid and meningitis in a 33-year-old male originated from an encephalic herniation into the middle ear following traumatic temporal bone fracture. CT demonstrated a mixed-type fracture consisting of a longitudinal fracture and a posterior oblique fracture of the left temporal bone. Th...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.1080/00016480510029266

    authors: Nishiike S,Miyao Y,Gouda S,Shimada N,Nagai M,Nakagawa A,Konishi M,Sakata Y

    更新日期:2005-08-01 00:00:00

  • Immunohistological analysis of eotaxin and RANTES in the model animal of eosinophilic otitis media.

    abstract:BACKGROUND:The most crucial clinical problem of Eosinophilic Otitis Media (EOM) is sensorineural hearing loss. A previous report revealed that repeated antigen stimulation of middle ear causes eosinophilic inflammation not only in the middle ear but also in the inner ear. OBJECTIVE:The purpose of the present study was...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.1080/00016489.2016.1266508

    authors: Kudo N,Matsubara A,Nishizawa H,Miura T

    更新日期:2017-05-01 00:00:00

  • Experimental acute sinusitis in rabbits. Energy metabolism in sinus mucosa and secretion.

    abstract::In previous studies, sinus secretions have been analysed concerning pO2, pCO2 and pH. In this study the energy metabolism in the maxillary sinus mucosa and secretion was studied in 33 New Zealand White rabbits. In freeze-dried samples, glucose and lactate were analysed by enzymatic assays and ATP by HPLC. In the purul...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.3109/00016488809122271

    authors: Johansson P,Kumlien J,Söderlund K,Hultman E

    更新日期:1988-11-01 00:00:00

  • Prospective multi-center study on expansion sphincter pharyngoplasty.

    abstract:BACKGROUND AND OBJECTIVE:The aim of this study was to demonstrate the long-term effectiveness of Expansion Sphincter Pharyngoplasty (ESP) as a standalone surgical treatment of obstructive sleep apnea-hypopnea syndrome (OSAHS) patients through a prospective multi-center study. MATERIAL AND METHODS:A prospective non-com...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章,多中心研究

    doi:10.1080/00016489.2018.1533992

    authors: Plaza G,Baptista P,O'Connor-Reina C,Bosco G,Pérez-Martín N,Pang KP

    更新日期:2019-02-01 00:00:00

  • Cis-diaminedichloro platinum ototoxicity. An experimental study.

    abstract::Four groups of guinea pigs received different doses of cis-platinum. SEM and TEM showed a direct relation between the dose and the damage. The first row of OHC is the first one to be damaged. The IHC are more resistant than the OHC. The pattern of destruction is similar to the one produced by the aminoglucoside antibi...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.3109/00016488509108921

    authors: Marco-Algarra J,Basterra J,Marco J

    更新日期:1985-03-01 00:00:00

  • Role of margin status in recurrence after CO2 laser endoscopic resection of early glottic cancer.

    abstract:CONCLUSION:In patients with early glottic squamous cell carcinoma (SCC) submitted to CO2 laser endoscopic resection, local disease recurrence was significantly correlated with the presence of positive additional surgical margins on permanent sections. OBJECTIVES:To evaluate the rate of cancer recurrence in patients wi...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.1080/00016480500316985

    authors: Crespo AN,Chone CT,Gripp FM,Spina AL,Altemani A

    更新日期:2006-03-01 00:00:00

  • Mucin gene expression in nasal polyps.

    abstract:CONCLUSIONS:A large set of mucin genes is expressed in nasal polyps. The expression pattern is complex and may reflect the wide spectrum of variables involved in polyp formation and progression. Prospective studies including subgroups of nasal polyps and involving substantial numbers of cases in each subgroup will be r...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.1080/00016480510027538

    authors: Ali MS,Wilson JA,Bennett M,Pearson JP

    更新日期:2005-06-01 00:00:00

  • How effect is educational counseling prior to middle ear surgery for patients with both middle ear diseases and consistent tinnitus?

    abstract::Background: The management of patients with tinnitus who receive middle ear surgery has not been established.Aims: The aim of this study is (1) how many patients who receive middle ear surgery have tinnitus and (2) how educational counselling and middle ear surgery is effective with consistent tinnitus.Subjects and me...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.1080/00016489.2020.1713397

    authors: Kanzaki S,Ogawa K

    更新日期:2020-04-01 00:00:00

  • Elemental composition of individual cells and tissues in the cochlea.

    abstract::Localization of elements at the cellular and sub-cellular levels was performed with the energy dispersive X-ray microanalysis technique, using shock-frozen, freeze-dried and araldite-embedded mouse (CBA/CBA) cochleae sectioned dry. Anatomical identification occurred in the STEM (scanning transmission electron microsco...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.3109/00016488409107585

    authors: Anniko M,Lim D,Wróblewski R

    更新日期:1984-11-01 00:00:00

  • Hemolysis in neonatal rats results in auditory impairment.

    abstract:CONCLUSION:This study suggests that hyperbilirubinemia in the neonatal rat can impair auditory function and induce peripheral nerve pathology by reducing neurofilament-positive cells in spiral ganglion neurons (SGNs). This finding indicates a potential connection between hyperbilirubinemia and auditory impairment. OBJ...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.3109/00016489.2014.938361

    authors: Li Q,Chen P,Guo W,Fang R,Yang S

    更新日期:2014-11-01 00:00:00

  • How we do it: a combined method of traditional curette and power-assisted endoscopic adenoidectomy.

    abstract:CONCLUSION:After conventional curette adenoidectomy, a significant mass of residual adenoid tissue is observed in about 50% of the cases. The combined approach of conventional curette and endoscopic adenoidectomy with microdebrider assures a complete and accurate removal of the mass. It is an effective and safe method ...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.1080/00016480802294377

    authors: Pagella F,Matti E,Colombo A,Giourgos G,Mira E

    更新日期:2009-05-01 00:00:00

  • The natural course of allergic rhinitis: a 32-year follow-up study.

    abstract:CONCLUSION:Early intervention may change the natural course of allergic rhinitis, preventing the progression to asthma. In particular, immunotherapy guarantees remission of local symptoms and valid protection against local and bronchial complications. Symptomatic treatment represents a valid alternative; it is always t...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.3109/00016489.2013.815362

    authors: Passali GC,Bellussi LM,De Corso E,Passali FM,Passali D

    更新日期:2013-11-01 00:00:00

  • Artifacts in eighth cranial nerve biopsy.

    abstract::The occurrence of artifactual morphological changes was investigated in human eighth nerve biopsies and corresponding changes were brought about in biopsies from rats by mechanical handling before fixation. At the very site of compression by a pair of forceps the biopsy stained lighter than in its immediate surroundin...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.3109/00016488009127111

    authors: Collan Y,Ylikoski J,Palva T,Selamaa R

    更新日期:1980-01-01 00:00:00

  • Dynamic upper airway changes during sleep in patients with obstructive sleep apnea syndrome.

    abstract:CONCLUSION:The narrowing pattern of the upper airway in obstructive sleep apnea patients may be different in sleep as compared with awake. Three different types of obstruction were observed in these subjects during drug-induced sleep. The different obstruction pattern during drug-induced sleep suggests that different s...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.3109/00016480902780242

    authors: Chuang LP,Chen NH,Li HY,Lin SW,Chou YT,Wang CJ,Liao YF,Tsai YH

    更新日期:2009-12-01 00:00:00

  • Facial nerve course in congenital aural atresia--identified by preoperative CT scanning and surgical findings.

    abstract:CONCLUSIONS:The facial nerve courses shown by preoperative CT imaging coincide with the surgical findings in most congenital aural atresia cases. CT scanning is critical in evaluation of a patient's candidacy for atresia surgery. OBJECTIVES:To evaluate the diagnostic value of preoperative CT scanning of the facial ner...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.1080/00016480801953064

    authors: Yu Z,Han D,Gong S,Wang Z,Dai H,Zhao S,Zheng Y,Leng T

    更新日期:2008-01-01 00:00:00

  • Production of otoconia in the endolymphatic sac in the Japanese red-bellied newt, Cynops pyrrhogaster: light and transmission electron microscopic study.

    abstract::The formation of otoconia in the endolymphatic sac (ES) of the larval newt, Cynops pyrrhogaster, has been studied by light and transmission electron microscopy. Some of the epithelial cells of the ES contain an abundance of swollen vesicles, Golgi complexes, rough endoplasmic reticula and ribosomes at the late larval ...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.1080/00016489850154694

    authors: Gao W,Wiederhold ML,Hejl R

    更新日期:1998-07-01 00:00:00

  • Combined endoscopic and transcutaneous approach for immobile parotid stones.

    abstract:CONCLUSION:Salivary stones in the parotid gland that are not amenable to endoscopic extraction can safely be removed by a combined, endoscopic-external approach. OBJECTIVE:Limitations for endoscopic removability of salivary stones from the parotid gland are immobile stones in the deeper salivary duct system. A combine...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.3109/00016489.2014.953204

    authors: Mikolajczak S,Bremke M,Beutner D,Luers JC

    更新日期:2015-01-01 00:00:00

  • Selective resection of the semicircular canals of rabbits with preservation of hearing.

    abstract::The goal of this investigation was to develop a method of surgical removal of the semicircular canals of the rabbit without induction of auditory impairment. Four different surgical techniques were utilized: i) fenestration of the lateral semicircular canal; ii) fibrin glue perfusion of the canal following fenestratio...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.3109/00016489209137490

    authors: Gjuric M,Wigand ME,Hosemann W

    更新日期:1992-11-01 00:00:00

  • Histological reaction to polyimide films in the cochlea.

    abstract::The biocompatibility of commercially available polyimides was examined in relation to the sensory and neural structures of the cochlea. Thin films of four different polyimides were prepared as substrates for photolithographically produced scala tympani electrode arrays and implanted in 32 cat cochleae. Following at le...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.3109/00016488909127474

    authors: Haggerty HS,Lusted HS

    更新日期:1989-01-01 00:00:00

  • A device for measuring mucociliary activity in the human bronchi during fibre-optic bronchoscopy.

    abstract::An in vivo method for the study of mucociliary activity in the human trachea and bronchi is presented. The method is based on a two-way fibre-optic system whereby reflections of light emitted by one glass-fibre and reflected by the cilia are picked up by a second glass fibre and transmitted to a recording unit. The gl...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.3109/00016489309135885

    authors: Huberman D

    更新日期:1993-09-01 00:00:00

  • Middle ear transmission losses caused by tympanic membrane perforations in cats.

    abstract::Losses (determined by measuring microphonic responses) were essentially identical, regardless of whether produced by admittance of sound into the middle ear via perforations in the tympanic membrane (TM) or in the bulla. With SPLs monitored directly at the TM, losses increased at 12 dB/oct with inverse frequency for f...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.3109/00016487609119970

    authors: Tonndorf J,McArdle F,Kruger B

    更新日期:1976-03-01 00:00:00

  • Inner ear injury caused by air intrusion to the scala vestibuli of the cochlea.

    abstract::In a previous communication, we demonstrated that the introduction of air into the scala tympani of the cochlea causes a decrease of cochlear potentials; however, the change in endocochlear dc potential (EP) was mild and the decreased cochlear microphonics (CM) and compound action potentials (CAP) were, at least parti...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.3109/00016489309135892

    authors: Kobayashi T,Sakurada T,Ohyama K,Takasaka M

    更新日期:1993-11-01 00:00:00

  • Interleukin 2 receptors on squamous cell carcinomas of the head and neck. Characterization and functional role.

    abstract::IL2Rs, in the presence of IL2, mediate activation and proliferation of human normal lymphocytes and modulate functional changes of some human leukocytic malignancies. IL2Rs have been demonstrated also on human neoplastic and fetal non-hematologic cells in vitro, although their functional role has not been described. W...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.1080/00016489.1992.11665436

    authors: Cortesina G,Sacchi M,Galeazzi E,Johnson JT,Whiteside TL

    更新日期:1992-01-01 00:00:00

  • Spiral modiolar vein: its importance in inner ear inflammation.

    abstract::The inner ear responds immunologically to foreign proteins and pathogens introduced into the cochlea. The route of entry of the cells participating in the inner ear inflammatory process is the spiral modiolar vein with its collecting venules. Since this vein is located adjacent to the scala tympani, the end result of ...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章,评审

    doi:10.3109/00016489009107455

    authors: Harris JP,Fukuda S,Keithley EM

    更新日期:1990-11-01 00:00:00

  • Ear, nose and throat manifestations of Churg-Strauss syndrome.

    abstract:CONCLUSION:Ear, nose and throat (ENT) involvement is common in Churg-Strauss syndrome (CSS), usually manifesting as allergic rhinitis and chronic rhinosinusitis with or without polyps. Otolaryngologists may play a pivotal role in making an early diagnosis of this disease. OBJECTIVES:CSS is a systemic vasculitic disord...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.1080/00016480500437435

    authors: Bacciu A,Bacciu S,Mercante G,Ingegnoli F,Grasselli C,Vaglio A,Pasanisi E,Vincenti V,Garini G,Ronda N,Ferri T,Corradi D,Buzio C

    更新日期:2006-05-01 00:00:00