Prospective multi-center study on expansion sphincter pharyngoplasty.

Abstract:

BACKGROUND AND OBJECTIVE:The aim of this study was to demonstrate the long-term effectiveness of Expansion Sphincter Pharyngoplasty (ESP) as a standalone surgical treatment of obstructive sleep apnea-hypopnea syndrome (OSAHS) patients through a prospective multi-center study. MATERIAL AND METHODS:A prospective non-comparative multicenter study of patients suffering from OSHAS selected after drug-induced sleep endoscopy, with ESP as standing alone procedure was performed. Inclusion criteria were lateral collapse on oropharynx and preoperative AHI between 5 and 70. Minimum follow-up was >12 months. Outcome measures were Epworth sleepiness scale (ESS), AHI, success rate and CPAP need after surgery. RESULTS:A total of 75 ESP were performed. Mean patient age was 46.7 ± 10.5 years. Mean pre-operative and post-operative AHI was 22.1 ± 12.2 and 8.6 ± 6.7, respectively (p < .001). Mean pre-operative and post-operative ESS score was 11.5 ± 4.7 and 4.6 ± 6.6, respectively (p < .001). AHI <5 was obtained in 25 patients (33.3%), and CPAP was not further needed after surgery in a total of 62 patients (82.6%). CONCLUSIONS AND SIGNIFICANCE:In this prospective multi-center study, patients undergoing ESP standing alone for the treatment of OSAHS have a reasonable expectation for success with minimal morbidity.

journal_name

Acta Otolaryngol

journal_title

Acta oto-laryngologica

authors

Plaza G,Baptista P,O'Connor-Reina C,Bosco G,Pérez-Martín N,Pang KP

doi

10.1080/00016489.2018.1533992

subject

Has Abstract

pub_date

2019-02-01 00:00:00

pages

219-222

issue

2

eissn

0001-6489

issn

1651-2251

journal_volume

139

pub_type

杂志文章,多中心研究
  • Long-term functional outcomes and quality of life after oncologic surgery and microvascular reconstruction in patients with oral or oropharyngeal cancer.

    abstract:CONCLUSIONS:Surgery for oral or oropharyngeal cancer with free-flap reconstruction is associated with moderate but persistent functional and quality of life (QoL) problems. Patient age, tumor stage, tumor site, and radiotherapy were the main predictors of functional outcome. OBJECTIVES:To evaluate long-term functional...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.3109/00016489.2014.913809

    authors: Pierre CS,Dassonville O,Chamorey E,Poissonnet G,Riss JC,Ettaiche M,Peyrade F,Benezery K,Chand ME,Leyssalle A,Sudaka A,Haudebourg J,Santini J,Bozec A

    更新日期:2014-10-01 00:00:00

  • Postnatal development of the auditory evoked brainstem potentials in the guinea pig.

    abstract::The postnatal development of lower stations in the auditory pathway was studied in the guinea pig by recording auditory brainstem potentials. At birth, the brainstem responses of young guinea pigs already have thresholds corresponding to those of adult animals. However, the latencies of the individual potentials are s...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.3109/00016488409130965

    authors: Dum N

    更新日期:1984-01-01 00:00:00

  • Smooth pursuit in senescence. Effects of target acceleration and velocity.

    abstract::Smooth pursuit responses to sinusoidal and triangular waveform targets were investigated in elderly and middle-aged subjects. The middle-aged pursued triangular targets with significantly lower gain than sinusoidal targets. In the elderly, pursuit gain was significantly lower than in the middle-aged under all target c...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.3109/00016488709107331

    authors: Zackon DH,Sharpe JA

    更新日期:1987-09-01 00:00:00

  • M2-polarized tumour-associated macrophages in stroma correlate with poor prognosis and Epstein-Barr viral infection in nasopharyngeal carcinoma.

    abstract:OBJECTIVES:To assess the relationships between CD163 expression, localization of CD163+ macrophages, clinicopathological features and prognosis of NPC. METHODS:A total of 110 cases of NPC specimens and 80 cases of nasopharyngitis specimens were analysed for CD163 expression by immunohistochemistry and EBERs expression...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.1080/00016489.2017.1296585

    authors: Huang H,Liu X,Zhao F,Lu J,Zhang B,Peng X,Zhang M,Chen X,Li G,Li X

    更新日期:2017-08-01 00:00:00

  • Artifacts in eighth cranial nerve biopsy.

    abstract::The occurrence of artifactual morphological changes was investigated in human eighth nerve biopsies and corresponding changes were brought about in biopsies from rats by mechanical handling before fixation. At the very site of compression by a pair of forceps the biopsy stained lighter than in its immediate surroundin...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.3109/00016488009127111

    authors: Collan Y,Ylikoski J,Palva T,Selamaa R

    更新日期:1980-01-01 00:00:00

  • Clinical outcome and comparison between squamous and non-squamous cell carcinoma of the larynx.

    abstract::Background: The various pathological types of non-squamous cell carcinomas (nSCCs) of the larynx accounted for about 5% laryngeal malignancies, but the knowledge regarding these pathological behaviors, therapeutic models and prognostic factors was limited.Objectives: To investigate the clinical characteristics and the...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.1080/00016489.2019.1700305

    authors: Chen L,Deng W,Li C,Lau H,Tao L,Wang S,Zhou L,Zhang M

    更新日期:2020-02-01 00:00:00

  • Dual symptomatic and exudative nasal responses are not characteristics of perennial allergic rhinitis.

    abstract::Acute and late phase (dual) symptomatic responses after allergen challenge commonly occur in allergic asthma. The aim of the present study was to explore the occurrence of allergen challenge-induced biphasic responses in patients with chronic perennial allergic rhinitis living in an area with high house dust mite (HDM...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.1080/000164801300102950

    authors: Andersson M,Rimmer J,Salome C,Greiff L,Persson C

    更新日期:2001-04-01 00:00:00

  • A comparison between nitric oxide output in the nose and sinuses: A pilot study in one volunteer.

    abstract::From a study of nitric oxide (NO) output in the nose and sinuses it seems that: (i) the results obtained regarding the regulation of NO output in the nose do not necessarily apply to the sinuses; (ii) the results obtained for one group of sinuses may not apply to another; and (iii) NO output in the sinuses does not be...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.1080/00016480510031524

    authors: Qian W,Mäkitie AA,Witterick I,Haight JS

    更新日期:2005-10-01 00:00:00

  • Auditory potentials in profoundly deaf subjects.

    abstract::In 12 healthy volunteers, and 5 prelingually and 5 postlingually profoundly deaf subjects, a 500 Hz filtered click stimulus was applied to the mastoid via the bone conductor. In all the healthy volunteers, middle latency response (MLR) was recorded. Among all profoundly deaf subjects, MLR was recorded only in 2 with p...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.3109/00016488509108929

    authors: Ribarić K,Padovan I,Prevec TS

    更新日期:1985-03-01 00:00:00

  • Heterologous epidermal growth factor receptor (EGF-R) expression in larynx cancer cell lines: evidence for the existence of structurally modified receptors.

    abstract::Overexpression of epidermal growth factor receptor (EGF-R) is a common characteristic of epidermoid tumors and its expression in head and neck squamous cell carcinoma biopsies and cell lines has been reported previously by several authors. With the aim to provide more structural and functional details about the protei...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.3109/00016489309135902

    authors: Bujía J,Wustrow TP

    更新日期:1993-11-01 00:00:00

  • Freeze-fracturing of vestibular sensory epithelia in a strain of the waltzing guinea pig.

    abstract::The waltzing guinea pig exhibits genetically induced inner ear disease which develops into deafness and vestibular disorder. The type I hair cell in vestibular end organs shows specific pathology, featuring protrusion of the hair cell apex, sensory hair fusion and an intracellular actin filament rod. With the freeze-f...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.3109/00016488309132893

    authors: Sobin A,Flock A,Bagger-Sjöbäck D

    更新日期:1983-09-01 00:00:00

  • Potential pitfalls and therapeutic implications of pretherapeutic radiologic staging in glottic cancers.

    abstract:OBJECTIVES:The aim of this study was to compare the radiologic findings with histological results of anatomically matched whole organ sections and to analyze the accuracy of pretherapeutic radiologic staging of glottic cancers. METHODS:The histologic findings of surgical specimens of 30 patients who had undergone tota...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.3109/00016489.2011.562538

    authors: Lim JY,Park IS,Park SW,Kim JW,Kim YM

    更新日期:2011-08-01 00:00:00

  • Heredity and symptoms in acromegaly.

    abstract::The author has performed clinical and follow-up studies of 80 acromegalic patients treated by transanthro-sphenoidal removal of the pituitary adenoma. Heredity for acromegaly or gigantism was recorded in 3.8% of the patients and other hereditary factors in 13.8%. Head trauma, meningitis or encephalitis was recorded in...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.3109/00016487609120891

    authors: Kinnman JE

    更新日期:1976-09-01 00:00:00

  • Electrocochleography and cochlear pathology.

    abstract::In experimentally damaged inner ears the structural alterations were correlated to electrocochleographic responses of the ear. Sectioning of the cochlear nerve with degeneration of the type I neurons but intact sensory cells results in normal cochlear microphonics but very weak and atypical nerve responses. By contras...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.3109/00016487709128822

    authors: Spoendlin H,Baumgartner H

    更新日期:1977-01-01 00:00:00

  • Substance P nerve fibres in the canine larynx by PAP immunohistochemistry.

    abstract::The distribution of the Substance P (SP) immunoreactive nerve fibres in the canine larynx and laryngeal nerves was studied by PAP immunohistochemistry. Many individual SP immunoreactive nerve fibres with varicosities were observed within the epithelial layer and in the connective tissue below the epithelium of the lar...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.3109/00016488509108597

    authors: Hisa Y,Sato F,Fukui K,Ibata Y,Mizukoshi O

    更新日期:1985-07-01 00:00:00

  • Automated image analysis of proliferating cells in carcinoma of the larynx.

    abstract:OBJECTIVE:To determine the role of cell proliferation neoplastic progression in the larynx and possibly derive criteria of clinical significance using automated quantitative image analysis. MATERIAL AND METHODS:In a retrospective study involving archival material, the occurrence and location, size, shape and staining ...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.1080/0001648021000028135

    authors: Laitakari J,Harrison D,Stenbäck F

    更新日期:2003-08-01 00:00:00

  • The influence of cigarette smoke on the pharyngeal mucosa.

    abstract::The influence of cigarette smoke on the pharyngeal mucosa was investigated in a clinical study and in an experiment on animals. Histologic reports were evaluated according to the Kambic-Lenart classification of hyperplastic aberrations of the throat mucosa. A close dependence of the degree of hyperplasia and the numbe...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.3109/00016487809121433

    authors: Radsel Z,Kambic V

    更新日期:1978-01-01 00:00:00

  • Sound quality in adult cochlear implant recipients using the HISQUI19.

    abstract:CONCLUSION:On average, adult CI recipients report a moderate sound quality using the Dutch version of the HISQUI19 questionnaire. These results are correlated with their age, speech perception scores, CI aided hearing thresholds, and the SSQ5 and the APHAB questionnaire. BACKGROUND:The general aim of the study was to ...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.3109/00016489.2015.1066934

    authors: Mertens G,Kleine Punte A,De Bodt M,Van de Heyning P

    更新日期:2015-01-01 00:00:00

  • Vestibulo-ocular responses during static head roll and three-dimensional head impulses after vestibular neuritis.

    abstract::This study aimed to investigate whether unilateral vestibular neuritis (VN) causes the same deficits of ocular counter-roll during static head roll (OCR(S)) and dynamic vestibulo-ocular reflex gains during head impulses (VOR(HI)) as unilateral vestibular deafferentation (VD). Ten patients with acute and 14 patients wi...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.1080/00016489950180379

    authors: Schmid-Priscoveanu A,Straumann D,Böhmer A,Obzina H

    更新日期:1999-01-01 00:00:00

  • Factors associated with successful decannulation in pediatric tracheostomy patients.

    abstract:OBJECTIVES:To investigate the outcome of pediatric tracheostomy and identify predictive factors for successful decannulation. METHODS:We performed a retrospective chart review of a series of 42 consecutive patients of less than 24 months of age who underwent a tracheostomy between 2012 and 2015. RESULTS:Successful de...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.1080/00016489.2017.1326064

    authors: Takahashi N,Takano K,Mitsuzawa H,Kurose M,Himi T

    更新日期:2017-10-01 00:00:00

  • Effects of chronic exposure to electromagnetic waves on the auditory system.

    abstract:CONCLUSION:The results support that chronic electromagnetic field exposure may cause damage by leading to neuronal degeneration of the auditory system. OBJECTIVES:Numerous researches have been done about the risks of exposure to the electromagnetic fields that occur during the use of these devices, especially the effe...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.3109/00016489.2015.1032434

    authors: Özgür A,Tümkaya L,Terzi S,Kalkan Y,Erdivanlı ÖÇ,Dursun E

    更新日期:2015-08-01 00:00:00

  • Effects of viral and bacterial infection on nasal and sinus mucosa.

    abstract::There is still controversy over the role of viruses and bacteria in rhinologic infections, especially in sinusitis. Until recently it was not fully known whether the sinuses do in fact take part in the infectious process of a common cold (viral rhinitis). CT scans show that in the vast majority of otherwise healthy vo...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章,评审

    doi:10.3109/00016489609137849

    authors: van Cauwenberge P,Ingels K

    更新日期:1996-03-01 00:00:00

  • Use of Swedish moist snuff, smoking and alcohol consumption in the aetiology of oral and oropharyngeal squamous cell carcinoma. A population-based case-control study in southern Sweden.

    abstract:CONCLUSIONS:The results of this study confirm that both smoking of tobacco and alcohol consumption are risk factors for oral and oropharyngeal squamous cell carcinoma (OOSCC). The use of moist snuff had no effect on the risk of OOSCC, probably due to the low levels of tobacco-specific N-nitrosamines in Swedish moist sn...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.1080/00016480510043440

    authors: Rosenquist K,Wennerberg J,Schildt EB,Bladström A,Hansson BG,Andersson G

    更新日期:2005-09-01 00:00:00

  • The role of the locus coeruleus in the gain regulation of vestibulospinal reflexes.

    abstract::In precollicular decerebrate cats, activation of limb extensors during side-down roll tilt of the animal depends on both an increased discharge of excitatory vestibulospinal neurons and a reduced discharge of inhibitory medullary reticulospinal (mRS) neurons. These inhibitory neurons are tonically excited by a choline...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:

    authors: Pompeiano O,Stampacchia G,Horn E,d'Ascanio P

    更新日期:1987-05-01 00:00:00

  • Acute tympanic membrane perforations and the early immunological response in rats.

    abstract:CONCLUSIONS:This study showed that macrophages, B cells, and T cells occurred at different frequencies, localizations, and times after acute laser tympanic membrane perforation. Immunological cells were most prevalent in the proliferative mass adjacent to the annulus region. The cellular immunological response in fresh...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.3109/00016480802669552

    authors: Tahar Aissa J,Hultcrantz M

    更新日期:2009-11-01 00:00:00

  • Inner ear autoantibodies and their targets in patients with autoimmune inner ear diseases.

    abstract::Immunological mechanisms are thought to play an important role in the pathogenesis of some cochleo-vestibular diseases. This study attempts to present further evidence of autoantibodies reactive against guinea pig inner ear proteins found in patients with autoimmune inner ear diseases (AIED) and specifically identifie...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.1080/000164801300006236

    authors: Boulassel MR,Deggouj N,Tomasi JP,Gersdorff M

    更新日期:2001-01-01 00:00:00

  • New techniques for optimum reconstruction of the facial nerve in its extemporal course.

    abstract::Microsurgery of the facial nerve has resulted in a great progress by regaining, thanks to its various techniques, not only the voluntary movements of the face but in addition also the emotional expressive motility. It has become evident, however, that one disadvantage is always unavoidable even in the most subtle reco...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.3109/00016488109138533

    authors: Miehlke A,Stennert E

    更新日期:1981-05-01 00:00:00

  • Study on the dye leakage response of nasal mucosa following topical, capsaicin challenge in guinea pigs.

    abstract::We examined the serial changes of intravenously applied dye leakage and preliminary examined histamine release into nasal lavage fluid after topical stimulation with capsaicin in guinea pigs. A significant increase in the dye leakage response was detected for 30-40 min, with the maximum response occurring between 5 an...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.3109/00016489209137438

    authors: Asakura K,Shirasaki H,Narita S,Kojima T,Kataura A

    更新日期:1992-01-01 00:00:00

  • Elective coniotomy. A prospective study.

    abstract::The view current over the last 60 years or so that coniotomy often leads to subglottic stenosis has recently been called into question. In the present study 103 electively performed coniotomies have been analysed. The operation was found to be much easier than tracheotomy. There was no case of severe peroperative or p...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.3109/00016488309132905

    authors: Holst M,Hedenstierna G,Kumlien JA,Schiratzki H

    更新日期:1983-09-01 00:00:00

  • Multifrequency tympanometry and histopathology in chinchillas with experimentally produced middle ear pathologies.

    abstract::Middle ear lesions were produced in chinchillas by introducing fascia, Gelfoam, silastic or a combination of these materials into the labyrinthine and mastoid bullae. After 1-2 months, conventional 226 Hz and multifrequency tympanometry (MFT) were performed and the animals were sacrificed for histopathological analysi...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.1080/00016489850154937

    authors: Margolis RH,Schachern PL,Fulton S

    更新日期:1998-03-01 00:00:00