Abstract:
CONCLUSIONS:This study showed that macrophages, B cells, and T cells occurred at different frequencies, localizations, and times after acute laser tympanic membrane perforation. Immunological cells were most prevalent in the proliferative mass adjacent to the annulus region. The cellular immunological response in freshly perforated eardrums was unexpectedly aggressive. OBJECTIVES:To study the occurrence of immunocompetent cells during the healing process of fresh perforated tympanic membranes. The information could be used to develop alternative outpatient procedures in the cure of chronic perforations, replacing conventional surgery. MATERIALS AND METHODS:A laser myringotomy was carried out in Sprague-Dawley rats, which were sacrificed at 3 and 6 days after the myringotomy. Tympanic membrane sections were stained immunohistochemically according to the avidin-biotin method, targeting macrophages, B cells, and T cells. Semi-quantification was performed; positive cells were counted and mean values were calculated. RESULTS:Macrophages and B cells were most frequent at day 6 and T cells at day 3 after laser myringotomy. B cells were the most prevalent studied cell type. T cells peaked at day 3, after which they decreased in number. Most immunocompetent cells were observed in the proliferative mass at the edge of the perforation.
journal_name
Acta Otolaryngoljournal_title
Acta oto-laryngologicaauthors
Tahar Aissa J,Hultcrantz Mdoi
10.3109/00016480802669552subject
Has Abstractpub_date
2009-11-01 00:00:00pages
1192-7issue
11eissn
0001-6489issn
1651-2251pii
10.3109/00016480802669552journal_volume
129pub_type
杂志文章abstract::Cochlear endolymph, scala tympani perilymph, and scala vestibuli perilymph were collected from fetal, neonatal, and mature guinea pigs. The concentrations of Na and K in these fluids were then assessed using a microflame photometer. The electrolyte composition in the endolymph was already characterized by a high conce...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016488509182256
更新日期:1985-05-01 00:00:00
abstract:OBJECTIVE:To evaluate the capability of indirect computed tomography and magnetic resonance lymphography (CT/MR-LG) with gadolinium-loaded, polyethylenimine-entrapped gold nanoprobes (Gd-Au PENPs) for assessing lingual sentinel lymph node (SLN) metastasis in a tongue VX2 carcinoma model. MATERIALS AND METHODS:Seventee...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016489.2018.1441544
更新日期:2018-08-01 00:00:00
abstract::The aim of the present study is to construct a reference model with the indication for the attitude, the requirements and the resources needed in order to be able to deal with deafness in the presence of disabilities or associated problems. The study group consisted of 13 adults and 18 children affected by profound de...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/03655230410017193
更新日期:2004-04-01 00:00:00
abstract:CONCLUSION:An 18-mer peptide derived from the neurotrophic region of prosaposin (PS-pep) prevents hearing loss and cochlear damage due to transient cochlear ischaemia by activating an anti-apoptotic pathway. PS-pep is a potent candidate molecule for alleviating ischaemia-induced hearing loss. OBJECTIVE:PS-pep was inve...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489.2012.750430
更新日期:2013-05-01 00:00:00
abstract::Seventeen cases of postinflammatory acquired artresia of the external auditory canal in 14 women are described and analysed. Fourteen of these cases were solid atresias in which the auditory canal was more or less filled with fibrous tissue. Three patients had partial membranous atresia. The aetiology was external oti...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016487509124663
更新日期:1975-01-01 00:00:00
abstract::Five out of eight consecutive cases with initial symptoms of a 'midline granuloma' were identified as malignant histiocytosis (histiocytic sarcoma) which within 5 months to 4 years led to generalization and death. The three remaining cases also fulfilled the morphological criteria of this type of neoplasia, though the...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016488609108616
更新日期:1986-01-01 00:00:00
abstract::The basement membrane zone (BMZ) of the epithelium of the vocal folds was investigated electron microscopically in 10 patients suffering from various benign lesions and in 3 controls. Various defects were observed: a thickening by deposition of electron dense material, a loss of normal architecture, and a near absence...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489309135774
更新日期:1993-01-01 00:00:00
abstract::In a previous paper we demonstrated physiologically a sensitive period for acoustic trauma in the rat pup cochlea, with a maximum at 22 days of age. Seven or 60 days after noise exposure these 22-day exposed rats were used for light and electron microscopy. At 7 days, surface preparation revealed restricted damage to ...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016488009127143
更新日期:1980-03-01 00:00:00
abstract::Nerves displaying vasoactive intestinal peptide (VIP) immunoreactivity were detected in the upper respiratory tract of guinea pigs, rabbits and cats. VIP nerves were numerous in the cat, less numerous in the rabbit and rare in the guinea pig. In the nasal mucosa, fine varicose VIP nerves were found to surround nasal g...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016487809107524
更新日期:1978-11-01 00:00:00
abstract::The symptoms, preoperative diagnostic results and histological findings in 34 cerebellopontine angle tumour cases, other than acoustic neuromas, are presented. The meningeomas dominate by far this group of tumours. The symptomatology is much less uniform than that of the acoustic neuromas, where the VIII nerve is domi...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016487609120868
更新日期:1976-07-01 00:00:00
abstract::Human secretory leucocyte proteinase inhibitor (SLPI) is a low-molecular weight, acid-stable inhibitor of polymorph-nuclear granulocyte elastase and cathepsin G. Previous reports have demonstrated the existence of SLPI in the respiratory tract, salivary glands and cervical mucosa. Positive staining for SLPI using immu...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489409126042
更新日期:1994-03-01 00:00:00
abstract:CONCLUSION:Cone Beam Computed Tomography (CBCT) can be widely used in imaging of bony structures of the anterior and lateral skull base. Significant differences of applied dosages result from the different protocols of the various indications. OBJECTIVES:CBCT is increasingly being used in head and neck imaging. Until ...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489.2015.1076172
更新日期:2015-01-01 00:00:00
abstract::Utilizing an enlarged middle cranial fossa approach to the cerebello-pontine angle without destruction of the labyrinth or cochlea the authors have since 1981 operated on 263 unilateral acoustic neurinomas. Tumour sizes ranged between 3 mm intrameatal and 35 mm within the cerebello-pontine angle. Complete tumour remov...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489209137419
更新日期:1992-01-01 00:00:00
abstract::To predict the possible benefit of a cochlear implant to a patient, the clinician requires a reliable objective method to monitor the presence of surviving fibres in the 8th nerve. The subjective promontory test and the evaluation of electrically evoked brainstem potentials are not adequate. An electrical stimulus art...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489409126093
更新日期:1994-09-01 00:00:00
abstract::The symptoms of postural instability and dizziness associated with decompression sickness could be ascribed to either damage of the vestibular apparatus or to central nervous system damage. However, a histological study of monkeys exposed to decompression reveals that these symptoms primarily result from damage to the...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016488009131707
更新日期:1980-01-01 00:00:00
abstract::The experimental use of jejunal free grafts with microvascular anastomosis in the head and neck region has been reported in pharyngeal and esophageal reconstruction. Lack of a suitable animal model has limited basic research for cutaneous or myocutaneous microvascular techniques. This investigation upon appropriate gr...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016488409107574
更新日期:1984-09-01 00:00:00
abstract::The diagnosis and management of spontaneous otogenic pneumocephalus with literature review is described. A young sportsman experienced headache and fluctuating mass in his occiput during increased physical activity. A large extradural intracranial pneumocephalus with corresponding emphysema was imaged on a CT scan. Tr...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章,评审
doi:10.3109/00016489.2010.541941
更新日期:2011-06-01 00:00:00
abstract::Blood circulation in the cochlear lateral wall after exposure to a non-physiological level of sound (120-125 dB SPL, 3 h) was investigated immunohistologically. Kanamycin (KM), which was expected to function as a tracer of blood flow, was administered to guinea pigs 5 min to 21 h after sound termination. At 5-30 min, ...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489109137358
更新日期:1991-01-01 00:00:00
abstract::Background: Chronic exposure to whole body vibration can affect the gastrointestinal system, the lumbar spine, the peripheral veins and the vestibulocochlear system. Aims/Objectives: The aim of this study was to evaluate the effects of vibration on the vestibular system in noisy and noise-free environments using the v...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016489.2019.1666213
更新日期:2019-11-01 00:00:00
abstract:BACKGROUND:The most crucial clinical problem of Eosinophilic Otitis Media (EOM) is sensorineural hearing loss. A previous report revealed that repeated antigen stimulation of middle ear causes eosinophilic inflammation not only in the middle ear but also in the inner ear. OBJECTIVE:The purpose of the present study was...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016489.2016.1266508
更新日期:2017-05-01 00:00:00
abstract:CONCLUSIONS:Intratympanic steroid (ITS) treatment groups exhibited better outcomes in PTA improvement and recovery rate than systemic steroid therapy (SST) groups. Whether initial hearing loss severity would influence the PTA improvement and recovery rate still requires further research. OBJECTIVE:This article was aim...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章,meta分析
doi:10.1080/00016489.2016.1260157
更新日期:2017-06-01 00:00:00
abstract::By means of cleaving the soft palate and blocking the Eustachian tube, two otomicroscopically well defined types of otitis media, serous and purulent, were created in an animal model (rat). The microbiological pattern of these conditions were characterized at 1, 2, 3, 4 and 6 weeks after the onset. Samples were collec...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489009122521
更新日期:1990-07-01 00:00:00
abstract::Following responses to constant velocity and sinusoidally oscillating movements of the whole visual environment were examined in normal subjects wearing blinkers to obscure central vision or subjected to a photo flash to induce a central scotoma, in patients with central scotomas of pathological origin and in one pati...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016487909126455
更新日期:1979-05-01 00:00:00
abstract:CONCLUSIONS:In skilled hands, selective embolization is a safe procedure and represents an effective treatment for prolonged epistaxis. Embolization therapy can be repeated if necessary. OBJECTIVE:Severe posterior epistaxis is a common clinical problem in an ENT department and controlling the bleeding may present diff...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016480410023029
更新日期:2005-03-01 00:00:00
abstract::Simultaneous monitoring in human subjects on the same ear of eardrum displacement by tympanomanometry, and impedance with the electroacoustic bridge, provided information concerning contraction of the stapedius muscle and its effect on eardrum displacement. Extensive control procedures were employed to elicit only the...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016487609107472
更新日期:1976-01-01 00:00:00
abstract::Little is known about the physiologic regulation of the vestibular end organ blood flow. The purpose of the current study was to examine posterior semicircular canal ampulla blood flow in addition to systemic factors during intravenous infusions of calcitonin-gene related peptide (CGRP), a factor involved in the tonic...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489709114207
更新日期:1997-11-01 00:00:00
abstract::The vestibular and optokinetic responses of a group of white cats were evaluated and compared with the responses from a control group of pigmented animals. The results indicate that in all cases the white cats exhibited varying degrees of vestibular and/or optokinetic dysfunction, which in some animals varied from tes...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016487709123944
更新日期:1977-07-01 00:00:00
abstract:CONCLUSION:Results from a database for sudden sensorineural hearing loss (SSNHL) demonstrate no correlation between laboratory findings, treatment, and outcome in 400 patients. The patients with pathological test results were not treated differently from those with normal test results. The value of laboratory findings ...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016480903161541
更新日期:2010-03-01 00:00:00
abstract:BACKGROUND:Endolymphatic sac decompression has shown limited success for the treatment of Ménière's disease (MD). We have published a novel technique with very promising results for the treatment of refractory MD: the Endolymphatic Duct Blockage (EDB) with two titanium clips. One of the challenges of this technique was...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016489.2018.1481524
更新日期:2018-10-01 00:00:00
abstract:CONCLUSION:Salivary gland diseases should be handled with a high index of suspicion. Although an inference could be drawn it is not clear from this study if primary head and neck cancers (HNCs) have a significant association with HIV/AIDS. OBJECTIVE:HIV/AIDS manifestations and malignancies do occur in the head and nec...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016480701230936
更新日期:2007-11-01 00:00:00