Abstract:
:The experimental use of jejunal free grafts with microvascular anastomosis in the head and neck region has been reported in pharyngeal and esophageal reconstruction. Lack of a suitable animal model has limited basic research for cutaneous or myocutaneous microvascular techniques. This investigation upon appropriate graft sites in the canine was instituted. Following a vertical hemilaryngectomy, reconstruction of the laryngeal defect was accomplished by transferring 2.5 to 3.5 centimeters square of a free myocutaneous graft from the caudal ventral abdominal region. The skin surface of the graft was placed inward to reline the laryngeal lumen. The epigastric artery and vein attached to the free graft were anastomosed to the superior thyroid or laryngeal artery or vein. Four of the six animals survived the procedure. All animals which survived the surgery showed excellent preservation of the airway lumen, pseudocord formation, and viability of the graft.
journal_name
Acta Otolaryngoljournal_title
Acta oto-laryngologicaauthors
Duncavage JA,Feider DE,Hobbs JD,Toohill RJdoi
10.3109/00016488409107574subject
Has Abstractpub_date
1984-09-01 00:00:00pages
362-7issue
3-4eissn
0001-6489issn
1651-2251journal_volume
98pub_type
杂志文章abstract:CONCLUSION:The circling mouse (cir/cir) has phenotypes which follow the pattern of neuroepithelial defects of deafness from 10 days after birth. The cir mouse is defective in Tmie gene, the function of which should be further elucidated. OBJECTIVES:We previously reported a recessive mutation of deafness called circlin...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016480600827071
更新日期:2007-03-01 00:00:00
abstract::Most epidemiological surveys concerning populations exposed to occupational noise or random populations have shown that the left ear is slightly but significantly poorer than the right ear, especially at frequencies most susceptible to noise damage. To experimentally study the possible left-right asymmetry in response...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489109138399
更新日期:1991-01-01 00:00:00
abstract::The inner ear distortion induced by gentamicin (GM), a type of aminoglycoside antibiotic, was examined in guinea-pigs. Previous studies which investigated the function of the eighth cranial nerve and organ of Corti using cochlear microphonics (CM) and compound action potential (CAP) reported ototoxicity following expe...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016489850183449
更新日期:1998-06-01 00:00:00
abstract::Two hundred Malaysian patients representing 227 ears with previously untreated cholesteatoma disease were analysed retrospectively in terms of i) type of disease, i.e. primary acquired attic defect or posterior superior retraction pocket and secondary acquired type cholesteatoma; ii) positive history of previous middl...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489109138380
更新日期:1991-01-01 00:00:00
abstract:CONCLUSION:This 3D prototyped model constructed using a selective laser sintering method serves as a good material for surgical simulation of a malformed ear. OBJECTIVE:In order to perform surgery of the malformed ear, a thorough understanding of the anatomy of the ear is required, together with sufficient experience....
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016480410016874
更新日期:2005-01-01 00:00:00
abstract::Synthesis of prostaglandins (PGs) was characterized in the lateral wall (LW) of guinea-pig cochlea. Basal synthesis at 37 degrees C was about 480 pg/LW (12.8 ng X mg-1 protein) for PGI2 and 85 pg/LW (2.3 ng X mg-1 protein) for PGE2, levelling out after 10 min of incubation. Incubation with arachidonic acid (10(-5) M) ...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:
更新日期:1987-05-01 00:00:00
abstract:CONCLUSION:The palatal implant method originally designed to reduce snoring can significantly reduce the apnea-hypopnea index (AHI) in some patients with mild to moderate obstructive sleep apnea (OSA) in a single office-based procedure. OBJECTIVE:An initial study designed to evaluate the short-term efficacy and safety...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016480600951392
更新日期:2007-05-01 00:00:00
abstract::The blowing of chilled (14 degrees C) air into the external auditory canal (EAC) resulted in a profuse middle ear fluid production. The stimulation caused marked changes in the pars flaccida of the tympanic membrane. A slight vasodilatation was noted in the oedematous loose connective tissue layer of the pars flaccida...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016488609108674
更新日期:1986-09-01 00:00:00
abstract:CONCLUSION:Results from a database for sudden sensorineural hearing loss (SSNHL) demonstrate no correlation between laboratory findings, treatment, and outcome in 400 patients. The patients with pathological test results were not treated differently from those with normal test results. The value of laboratory findings ...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016480903161541
更新日期:2010-03-01 00:00:00
abstract::The present study on the anatomy of the human facial nerve is based on the results of a series of gross dissections, and histological and electro-diagnostic examinations. From our findings it follows that there is a definite spatial orientation of the peripheral branches in the facial nerve trunk. The results of the m...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016487609119946
更新日期:1976-03-01 00:00:00
abstract:CONCLUSION:Concomitant antiemetic therapy comprising fosaprepitant, palonosetron, and dexamethasone is effective for head and neck carcinoma. OBJECTIVE:A patient diary was constructed to determine the effectiveness of concomitant antiemetic therapy with a neurokinin-1 receptor antagonist (fosaprepitant), 5-hydroxytryp...
journal_title:Acta oto-laryngologica
pub_type: 临床试验,杂志文章
doi:10.3109/00016489.2014.913314
更新日期:2014-11-01 00:00:00
abstract::The present paper presents monopolar recording of facial nerve antidromic potentials as an alternative technique to facial electromyography for the continuous monitoring of the facial nerve during acoustic neuroma surgery. The investigation involved 22 patients undergoing acoustic neuroma surgery via a retrosigmoid ap...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489709113457
更新日期:1997-09-01 00:00:00
abstract:OBJECTIVE:To report on the long-term results, focusing on prosthesis lifetime, achieved with the VoiceMaster prosthesis in an outpatient population. MATERIAL AND METHODS:The VoiceMaster prosthesis was used over a 40-month period. Average prosthesis lifetimes were calculated both individually and for the group as a who...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016480310001330
更新日期:2003-06-01 00:00:00
abstract:CONCLUSION:The addition of transoral robotic surgery (TORS) in the diagnostic management of patients classified with head and neck squamous cell carcinoma of unknown primary (SCCUP) is promising and appears to improve detection rates of the primary tumour. The approach presented in this first Scandinavian study could p...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489.2015.1052983
更新日期:2015-01-01 00:00:00
abstract:CONCLUSION:These findings indicate a strong protective effect of ALCAR and NAC on impulse noise-induced cochlear damage, and suggest the feasibility of using clinically available antioxidant compounds to protect the ear from acute acoustic injury. OBJECTIVE:Reactive oxygen species have been shown to play a significant...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016480410023038
更新日期:2005-03-01 00:00:00
abstract:CONCLUSION:This study suggests that hyperbilirubinemia in the neonatal rat can impair auditory function and induce peripheral nerve pathology by reducing neurofilament-positive cells in spiral ganglion neurons (SGNs). This finding indicates a potential connection between hyperbilirubinemia and auditory impairment. OBJ...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489.2014.938361
更新日期:2014-11-01 00:00:00
abstract:CONCLUSION:This work demonstrated that juvenile nasopharyngeal angiofibromas (JNAs) express high levels of hormone receptors and vascular endothelial growth factor (VEGF) compared with normal nasal mucosa. The interaction between hormone receptors and VEGF may be involved in the initiation and growth of JNA. OBJECTIVE...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489.2014.952774
更新日期:2015-01-01 00:00:00
abstract::This is a study of the effects of repeated angular acceleration on the activity of vestibular nuclei units in anesthetized and in conscious cats. The experimental animals were subjected to trains of repeated and consecutive constant acceleration-deceleration ramps (4-8 degrees/sec2). In a few cases nystagmus was recor...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016488009131713
更新日期:1980-09-01 00:00:00
abstract:CONCLUSION:Our findings suggest that there exists a Na(+) transport system in the cochlea consisting of SGK1, Nedd4 isoforms and ENaC, which may work in concert to transport Na(+) and to maintain homeostasis in the inner ear as they do in other tight epithelia. OBJECTIVES:It has been well demonstrated that the epithel...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016480802552501
更新日期:2009-09-01 00:00:00
abstract::Serially cultivated rat middle ear epithelium was studied under exposure to various concentrations of carbon dioxide. Three experiments were performed exposing the epithelium to a gaseous environment containing 5 or 10% CO2 or to an atmosphere almost devoid of CO2. Oxygen was maintained constant at 20% and nitrogen wa...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489009125165
更新日期:1990-05-01 00:00:00
abstract:CONCLUSION:Continuous positive airway pressure (CPAP) therapy improved not only apnea-hypopnea during sleep and sleep structure but also sleep-related deglutition, especially respiratory phase patterns associated with deglutition. OBJECTIVES:Sleep-related deglutition and related respiratory phase patterns in patients ...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489.2010.520166
更新日期:2011-02-01 00:00:00
abstract:CONCLUSION:Abnormal caloric and vestibular evoked myogenic potential (VEMP) responses are frequently encountered with a large cerebellopontine angle (CPA) schwannoma, while normal caloric responses and abnormal VEMPs are noted with a large CPA meningioma. This difference may possibly exist because schwannoma causes ves...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016480802126553
更新日期:2009-02-01 00:00:00
abstract:CONCLUSION:Speech thresholds measured using Cantonese Hearing in Noise Test (CHINT) and cortical evoked response audiometry (CERA) thresholds were highly correlated with pure-tone behavioral results. Both tests are considered to provide good estimates of hearing thresholds and can be employed to confirm the degree of h...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016480701642189
更新日期:2008-06-01 00:00:00
abstract:OBJECTIVE:To investigate the outcome of surgically managed laryngeal carcinoma patients attending an outpatient clinic over a 5-year period. MATERIAL AND METHODS:This was an analytical, retrospective, cross-sectional study. A total of 36 laryngeal carcinoma patients who were managed surgically with or without radiothe...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016480410018070
更新日期:2004-08-01 00:00:00
abstract::The early diagnosis of the Mondini dysplasia by means of electrocochleography and temporal bone polytomography, and the prevention of further hearing loss through the endolymphatic subarachnoid shunt operation, brought new data on the follow-up of patients with this malformation. They were found to present specific me...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016488309139454
更新日期:1983-05-01 00:00:00
abstract:CONCLUSION:The Na-K-2Cl cotransporter-1 (NKCCl) may be essential for the maintenance and functioning of the vestibular morphology in mice and it is strongly expressed in human vestibular end organs. OBJECTIVE:NKCCl is a member of the cation-coupled chloride transporter which participates in salt transport and cell vol...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016480510012309
更新日期:2005-12-01 00:00:00
abstract::In experimental autoimmune labyrinthitis, we found that the guinea pigs sensitized with bovine inner ear antigen (IEAg) developed cellular infiltration within the endolymphatic sac (E. sac). In this study, we investigated the distribution of immune mediated cells within bony vascular channels. The channels, which are ...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489309135786
更新日期:1993-03-01 00:00:00
abstract::We studied int-2 and bcl-1 gene amplification in 21 operated patients with cancer of the larynx. In 9 cases, the int-2 gene was amplified (42.9%) and in 4 cases. the bcl-1 gene was amplified (25.0%). Co-amplification of int-2 and bcl-1 was observed in three cases (18.8%), all of which were glottic carcinomas. Other am...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016489850183331
更新日期:1998-09-01 00:00:00
abstract:BACKGROUND:Supracricoid partial laryngectomy (SCL) can have a positive impact on patients' quality of life by circumventing dysphagia and voice problems resulting from creation of a permanent stoma after conventional total laryngectomy (TL) surgery. AIMS/OBJECTIVES:The aim of this study was to investigate the oncologi...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016489.2018.1506154
更新日期:2018-12-01 00:00:00
abstract::IL2Rs, in the presence of IL2, mediate activation and proliferation of human normal lymphocytes and modulate functional changes of some human leukocytic malignancies. IL2Rs have been demonstrated also on human neoplastic and fetal non-hematologic cells in vitro, although their functional role has not been described. W...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016489.1992.11665436
更新日期:1992-01-01 00:00:00