Comparison of vestibular function between large cerebellopontine angle meningioma and schwannoma.

Abstract:

CONCLUSION:Abnormal caloric and vestibular evoked myogenic potential (VEMP) responses are frequently encountered with a large cerebellopontine angle (CPA) schwannoma, while normal caloric responses and abnormal VEMPs are noted with a large CPA meningioma. This difference may possibly exist because schwannoma causes vestibular deficits via parenchymal involvement, while vestibular deficits in the meningioma are mostly due to compression neuropathy. OBJECTIVES:This study aimed to compare the tumor characteristics in relation to vestibular function, i.e. caloric and VEMP responses, between large-sized (>2.5 cm) meningioma and schwannoma in the CPA. PATIENTS AND METHODS:Five patients with large CPA meningioma and nine patients with large CPA schwannoma were enrolled in this study. Each patient underwent a battery of tests including audiometry, caloric test, VEMP test, and MRI study. RESULTS:The meningioma group showed 20% caloric abnormality and 75% VEMP abnormality, while the schwannoma group revealed 100% caloric and 100% VEMP abnormalities. A significant difference existed in relation to caloric abnormality between the two groups, but not in relation to VEMP abnormality.

journal_name

Acta Otolaryngol

journal_title

Acta oto-laryngologica

authors

Hu YF,Cheng PW,Young YH

doi

10.1080/00016480802126553

subject

Has Abstract

pub_date

2009-02-01 00:00:00

pages

161-5

issue

2

eissn

0001-6489

issn

1651-2251

pii

794025663

journal_volume

129

pub_type

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