Localization of nontypeable Haemophilus influenzae endotoxin in the middle and inner ear during experimental otitis media.

Abstract:

:Nontypeable Haemophilus influenzae (NTHi) lipooligosaccharide, the major component of H. influenzae endotoxin, was localized in the middle and inner ear subsequent to the resolution of experimental otitis media induced by this pathogen. A monoclonal antibody specific for the lipooligosaccharide of this strain was used to probe sections of middle and inner ear tissue and visualized by means of the avidin-biotin peroxidase complex technique. Sixteen to seventeen days post inoculation with either viable or formalin-inactivated NTHi, endotoxin could be localized in both the middle and inner ear at a time when the middle ear was culture negative. Our data demonstrate that endotoxin shed by NTHi during otitis media penetrates the inner ear and binds to both tissue components and inflammatory cells in both the middle and inner ear.

journal_name

Acta Otolaryngol

journal_title

Acta oto-laryngologica

authors

Demaria TF

doi

10.1080/00016489950180838

subject

Has Abstract

pub_date

1999-01-01 00:00:00

pages

583-7

issue

5

eissn

0001-6489

issn

1651-2251

journal_volume

119

pub_type

杂志文章
  • Dynamic upper airway changes during sleep in patients with obstructive sleep apnea syndrome.

    abstract:CONCLUSION:The narrowing pattern of the upper airway in obstructive sleep apnea patients may be different in sleep as compared with awake. Three different types of obstruction were observed in these subjects during drug-induced sleep. The different obstruction pattern during drug-induced sleep suggests that different s...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.3109/00016480902780242

    authors: Chuang LP,Chen NH,Li HY,Lin SW,Chou YT,Wang CJ,Liao YF,Tsai YH

    更新日期:2009-12-01 00:00:00

  • Non-sentinel node tumor invasion in oropharyngeal and oral cancer: risk of misdiagnosis of metastasis.

    abstract:CONCLUSION:The existence of patients with positive non-sentinel node indicates a risk of misdiagnosis of metastasis in oropharyngeal and oral cancer. OBJECTIVES:We attempted to confirm the usefulness of sentinel lymph node biopsy (SLNB) in oropharyngeal and oral cavity cancer to detect clinically occult metastases. P...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.1080/00016480801891710

    authors: Santaolalla F,Sanchez JM,Ereño C,Gonzalez A,Rodriguez ML,Sanchez A,Martinez A

    更新日期:2008-10-01 00:00:00

  • Elemental composition of the mature inner ear.

    abstract::An X-ray energy dispersive analysis was performed on the mature serial sectioned freeze-dried mammalian labyrinth (CBA/CBA mouse). The elemental distribution in the endolymphatic and perilymphatic spaces revealed similar results as have been reported in the literature when withdrawing fluid for microanalysis. The cupu...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.3109/00016488009131744

    authors: Anniko M,Wroblewski R

    更新日期:1980-11-01 00:00:00

  • Postnatal development of vestibular receptor surfaces in the rat.

    abstract::The development of vestibular receptor surfaces was studied during the postnatal period in the rat on the 1st, 7th, 13th, 32nd and 75th days after birth. Cristae and utricles increase and change their shapes, up to day 13 for the cristae and day 32 for the utricles. Cristae hair bundles are less developed than those o...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.3109/00016488609108602

    authors: Dechesne C,Mbiene JP,Sans A

    更新日期:1986-01-01 00:00:00

  • Radiological analysis of swallowing and functional outcomes after hypopharyngo-laryngectomy with reconstruction using a jejunal autograft.

    abstract:CONCLUSION:We report a distinct pattern of tongue movement. This is interpreted as a compensatory mechanism after hypopharyngo-laryngectomy with reconstruction using a jejunal autograft. Passage through the oesophagus is mainly passive. OBJECTIVE:Swallowing is normally initiated voluntarily, and afterwards presumed to...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.3109/00016481003664785

    authors: Bakkan N,Boysen ME,Line PD,Aasen S

    更新日期:2010-09-01 00:00:00

  • The impact of comorbidity on the survival of patients with laryngeal squamous cell carcinoma.

    abstract:UNLABELLED:Abstract Conclusions: In survival analysis, the combined Charlson comorbidity index (CCI) can be considered as a prognostic factor independent of the tumor node metastasis (TNM) classification, tumor stage, and tumor location. Severe comorbidity was the factor that had the greatest impact on prognosis in cas...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.3109/00016489.2011.564651

    authors: Gimeno-Hernández J,Iglesias-Moreno MC,Gómez-Serrano M,Carricondo F,Gil-Loyzaga P,Poch-Broto J

    更新日期:2011-08-01 00:00:00

  • Hearing loss and vestibular dysfunction in Menière's disease.

    abstract::In a retrospective study of 475 patients suffering from Meniere's disease, the hearing loss, both in the low and high frequencies, and the loss of vestibular function were studied over time. There were large variations of hearing loss from case to case but, overall, the low were more affected than the high frequencies...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.3109/00016489609137819

    authors: Katsarkas A

    更新日期:1996-03-01 00:00:00

  • Amplification of int-2 and bcl-1 genes in squamous cell carcinoma of the larynx.

    abstract::We studied int-2 and bcl-1 gene amplification in 21 operated patients with cancer of the larynx. In 9 cases, the int-2 gene was amplified (42.9%) and in 4 cases. the bcl-1 gene was amplified (25.0%). Co-amplification of int-2 and bcl-1 was observed in three cases (18.8%), all of which were glottic carcinomas. Other am...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.1080/00016489850183331

    authors: Miyahara H,Naito H,Ueda K,Yane K,Matsunaga T,Okaichi K,Ohnishi T

    更新日期:1998-09-01 00:00:00

  • Comparison of different mobile telephones in Combi40+ users.

    abstract:CONCLUSION:Telephone usage is a difficult challenge for cochlear implanted patients. A significant number of cochlear implanted patients are able to carry on a land-line or mobile telephone conversation. The telephone model may be a critical factor for telephone performance. OBJECTIVES:The goals of this study were to ...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.1080/00016480500469552

    authors: Castro A,Lassaletta L,Bastarrica M,Prim MP,De Sarriá MJ,Gavilán J

    更新日期:2006-07-01 00:00:00

  • Auditory potentials in profoundly deaf subjects.

    abstract::In 12 healthy volunteers, and 5 prelingually and 5 postlingually profoundly deaf subjects, a 500 Hz filtered click stimulus was applied to the mastoid via the bone conductor. In all the healthy volunteers, middle latency response (MLR) was recorded. Among all profoundly deaf subjects, MLR was recorded only in 2 with p...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.3109/00016488509108929

    authors: Ribarić K,Padovan I,Prevec TS

    更新日期:1985-03-01 00:00:00

  • Prediction of upper respiratory tract bacteria in acute otitis media.

    abstract:CONCLUSIONS:Thorough otomicroscopical examination of the tympanic membrane in acute otitis media (AOM) might distinguish AOM episodes caused by different bacteria. It thus might be a way to select appropriate treatment for each patient without raising the number of dangerous complications. OBJECTIVES:The aim of this s...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.1080/00016480601091719

    authors: Foglé-Hansson M,White P,Hermansson A

    更新日期:2007-09-01 00:00:00

  • Assessment of lingual sentinel lymph nodes metastases using dual-modal indirect CT/MR lymphography with gold-gadolinium-based nanoprobes in a tongue VX2 carcinoma model.

    abstract:OBJECTIVE:To evaluate the capability of indirect computed tomography and magnetic resonance lymphography (CT/MR-LG) with gadolinium-loaded, polyethylenimine-entrapped gold nanoprobes (Gd-Au PENPs) for assessing lingual sentinel lymph node (SLN) metastasis in a tongue VX2 carcinoma model. MATERIALS AND METHODS:Seventee...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.1080/00016489.2018.1441544

    authors: Yang Y,Zhou B,Zhou J,Shi X,Sha Y,Wu H

    更新日期:2018-08-01 00:00:00

  • Effect of meteorological parameters on acute laryngitis in adults.

    abstract::The aim of this study was to investigate the influence of weather conditions on the frequency of acute laryngitis in adults. The medical records of 825 patients with a diagnosis of acute laryngitis obtained over a 5-year period were reviewed. Meteorological data reviewed included the daily values of 13 parameters. The...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.1080/000164802320396358

    authors: Danielides V,Nousia CS,Patrikakos G,Bartzokas A,Lolis CJ,Milionis HJ,Skevas A

    更新日期:2002-09-01 00:00:00

  • Vestibular and optokinetic responses of the white cat.

    abstract::The vestibular and optokinetic responses of a group of white cats were evaluated and compared with the responses from a control group of pigmented animals. The results indicate that in all cases the white cats exhibited varying degrees of vestibular and/or optokinetic dysfunction, which in some animals varied from tes...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.3109/00016487709123944

    authors: Waldorf RA,Polsinelli DJ,Knister JR,Kohut RI

    更新日期:1977-07-01 00:00:00

  • The relaxation time of the stapedius reflex in dystrophia myotonica (Steinert).

    abstract::Eight patients with dystrophia myotonica (Steinert) were studied. They all had myotonia and pathological EMG and in some cases other signs of the disease. The 50% relaxation times of the stapedius reflex were significantly prolonged compared with a control group of 40 healthy, young subjects with normal hearing and no...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.3109/00016488209128937

    authors: Zakrisson JE,Blom S

    更新日期:1982-11-01 00:00:00

  • High variability of perilymphatic entry of neutral molecules through the round window.

    abstract:OBJECTIVE:To improve the efficacy of intratympanic therapy using perilymphatic entry through the round window membrane. MATERIAL AND METHODS:The perilymphatic entry characteristics of 2 neutral molecules, mannitol (182.2 Da) and inulin (7,000 Da), were studied. A polyethylene catheter was placed in contact with the gu...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.1080/00016480310001042

    authors: Chelikh L,Teixeira M,Martin C,Sterkers O,Ferrary E,Couloigner V

    更新日期:2003-01-01 00:00:00

  • Comparative ototoxicity of furosemide and piretanide.

    abstract::The purpose of these studies was to compare the ototoxicity of piretanide to that of furosemide in the chinchilla. Chinchillas weighing 400 to 700 g were anesthetized with ketamine plus pentobarbital. Endocochlear potential (EP) was measured continuously by the round window approach using glass microelectrodes. Pireta...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.3109/00016488609108608

    authors: Rybak LP,Whitworth C

    更新日期:1986-01-01 00:00:00

  • Psychometric properties of the Standard-Chinese lexical neighborhood test.

    abstract:CONCLUSION:The psychometric characteristics of Standard-Chinese lexical neighborhood test (LNT) confirmed the lexical effects of the four word categories. The established normative baseline can be used in evaluating the word-recognition performance of the hearing-impaired listeners. OBJECTIVES:The purpose of the prese...

    journal_title:Acta oto-laryngologica

    pub_type: 临床试验,杂志文章

    doi:10.3109/00016489.2013.840923

    authors: Wang S,Liu S,Kong Y,Liu H,Feng J,Li S,Yang Y

    更新日期:2014-01-01 00:00:00

  • Rotation vector analysis of eye movement in three dimensions with an infrared CCD camera.

    abstract::We have developed a new technique for analyzing the rotation vector of eye movement in three dimensions with an infrared CCD camera based on the following four assumptions; i) the eye rotates on a point; ii) the pupil edge is a circle; iii) the distance from the center of eye rotation to pupil circle remains unchanged...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.1080/00016489950181882

    authors: Imai T,Takeda N,Morita M,Koizuka I,Kubo T,Miura K,Nakamae K,Fujioka H

    更新日期:1999-01-01 00:00:00

  • The evaluation of eustachian tube paratubal structures using magnetic resonance imaging in patients with chronic suppurative otitis media.

    abstract::Conclusion Eustachian tube (ET) dysfunction, which plays a role in the pathogenesis chronic suppurative otitis media (CSOM), does not seem to be due to differences in paratubal structures. Objective The aim of this study was to compare the magnetic resonance imaging (MRI) findings of the paratubal structures of the ET...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.3109/00016489.2016.1154187

    authors: Terzi S,Beyazal Çeliker F,Özgür A,Çeliker M,Beyazal M,Demirci M,Dursun E

    更新日期:2016-07-01 00:00:00

  • Clinical trial on tinnitus patients with normal to mild hearing loss: broad band noise and mixed pure tones sound therapy.

    abstract:BACKGROUND:Tinnitus treatments present a quandary for clinicians, but no thoroughly satisfactory medical treatments are offered to tinnitus patients. OBJECTIVE:We compared sound therapy effects of the broad band noise (BBN) and the mixed pure tones on tinnitus patients with normal to mild hearing loss, and the possibl...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章,随机对照试验

    doi:10.1080/00016489.2019.1575522

    authors: Li Y,Feng G,Wu H,Gao Z

    更新日期:2019-03-01 00:00:00

  • Value of pre-operative caloric test in predicting speech perception after cochlear implantation in adults with post-lingual hearing loss.

    abstract:CONCLUSION:This study shows that, in cochlear implantation (CI) surgery, pre-operative caloric test results are not correlated with post-operative outcomes of dizziness or speech perception. OBJECTIVES:To determine the role of pre-operative caloric tests in CI. METHODS:The records of 95 patients who underwent unilate...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.3109/00016489.2016.1172731

    authors: Yang CJ,Lee JY,Ahn JH,Lee KS

    更新日期:2016-09-01 00:00:00

  • Ultrastructural changes of the basement membrane zone in benign lesions of the vocal folds.

    abstract::The basement membrane zone (BMZ) of the epithelium of the vocal folds was investigated electron microscopically in 10 patients suffering from various benign lesions and in 3 controls. Various defects were observed: a thickening by deposition of electron dense material, a loss of normal architecture, and a near absence...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.3109/00016489309135774

    authors: Dikkers FG,Hulstaert CE,Oosterbaan JA,Cervera-Paz FJ

    更新日期:1993-01-01 00:00:00

  • Transforming growth factor beta 1 genotype and p16 as prognostic factors in head and neck squamous cell carcinoma.

    abstract:CONCLUSION:Transforming growth factor β1 gene (TGFβ1) genotype is a potential p16 independent prognostic factor predicting response to chemoradiotherapy in head and neck squamous cell carcinoma (HNSCC). OBJECTIVES:Expression of p16 and epidermal growth factor receptor (EGFR) has been reported to be associated with sur...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.3109/00016489.2012.678944

    authors: Lundberg M,Leivo I,Saarilahti K,Mäkitie AA,Mattila PS

    更新日期:2012-09-01 00:00:00

  • Ultrastructural localization of GABA-like immunoreactivity in the vestibular periphery of the rat.

    abstract::Gamma-aminobutyric acid (GABA) is presumed to be a neurotransmitter candidate in the vestibular periphery of mammals. However, experimental reports about the localization of GABA in afferents or efferents of the vestibular systems are contradictory. It is an open question whether there are species differences in the a...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.1080/00016489850155198

    authors: Kong WJ,Hussl B,Thumfart WF,Schrott-Fischer A

    更新日期:1998-01-01 00:00:00

  • Analysis on outcomes of facial paralysis complicated by middle ear cholesteatoma.

    abstract:BACKGROUND:The prognostic factors of facial paralysis complicated by middle ear cholesteatoma (MEC) are largely unknown due to limited reports and smaller sample size. OBJECTIVES:This study aimed to analyze prognostic factors of postoperative outcomes of facial paralysis complicated by MEC. MATERIAL AND METHODS:Clini...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.1080/00016489.2018.1543951

    authors: Li Q,Jia Y,Feng Q,Tang B,Luo X,Xu P,Wang D,Zhang X

    更新日期:2019-02-01 00:00:00

  • Soft palate implants as a minimally invasive treatment for mild to moderate obstructive sleep apnea.

    abstract:CONCLUSION:The palatal implant method originally designed to reduce snoring can significantly reduce the apnea-hypopnea index (AHI) in some patients with mild to moderate obstructive sleep apnea (OSA) in a single office-based procedure. OBJECTIVE:An initial study designed to evaluate the short-term efficacy and safety...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.1080/00016480600951392

    authors: Goessler UR,Hein G,Verse T,Stuck BA,Hormann K,Maurer JT

    更新日期:2007-05-01 00:00:00

  • Meniere's disease and middle ear pressure: vestibular function after transtympanic tube placement.

    abstract:CONCLUSION:Selected patients with Meniere's disease (MD) show an improvement of disability from vertigo after transtympanic ventilation tube insertion, although an effect on vestibular function is not seen if ipsilateral middle ear pressure lower than -50 daPa is used as a selection criterion. OBJECTIVES:Transtympanic...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.3109/00016480902791678

    authors: Park JJ,Chen YS,Westhofen M

    更新日期:2009-12-01 00:00:00

  • Traumatic retropharyngeal haematoma in an anticoagulated patient: Case report and proposal for a clinical protocol.

    abstract::Retropharyngeal haematomas (RPHs) are rare but potentially life-threatening conditions that require a prompt diagnosis. However, the clinical scenario is not always straightforward as their presentation may be insidious, with no specific signs or symptoms. Treatment of RPH is conservative in the majority of cases, wit...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.1080/00016480410017233

    authors: Chiti-Batelli S,Vaz F,Coman S

    更新日期:2005-04-01 00:00:00

  • Middle ear effusion induced by a stream of air in the external auditory canal. A temperature-related phenomenon.

    abstract::The blowing of chilled (14 degrees C) air into the external auditory canal (EAC) resulted in a profuse middle ear fluid production. The stimulation caused marked changes in the pars flaccida of the tympanic membrane. A slight vasodilatation was noted in the oedematous loose connective tissue layer of the pars flaccida...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.3109/00016488609108674

    authors: Goldie P,Hellström S

    更新日期:1986-09-01 00:00:00