Recovery period of sinonasal quality of life and its associated factors after endoscopic endonasal approach for anterior skull base tumors.

Abstract:

BACKGROUND:Although endoscopic endonasal approach (EEA) for skull base tumors showed a good prognosis in sinonasal quality of life (QOL), what factors have influence on QOL is still in question. Aim/Objectives: To investigate the recovery of sinonasal QOL after EEA for anterior skull base tumors and find its prognostic factors. MATERIAL AND METHODS:The study enrolled 250 patients undergoing EEA for anterior skull base tumors over 3 years. Sinonasal QOL was evaluated via sinonasal outcome test (SNOT-22) during 6 months. Age, gender, previous surgery, surgical extent, tumor pathology, combined surgical procedures, and surgical complications were analyzed. RESULTS:There were 101 male and 149 female with average 48.6 ± 16.1 years old. SNOT-22 increased from baseline (median 17.0; Q1-Q3 8.25-30.0) to postoperative 1 and 3 months (27.0; 15.0-36.0; p   <   .001 and 20.5; 11.0-32.0; p = .021, respectively) and it returned to the baseline within 6 months. Reconstruction with calcium hydroxyapatite and postoperative mucosal edema had a negative impact on the recovery (p  = .016 and .010, respectively), after adjustment for the baseline scores and postoperative months. CONCLUSIONS AND SIGNIFICANCE:Sinonasal QOL was recovered within 6 months. Avoidance of calcium hydroxyapatite could prevent delayed recovery. Surgeons should carefully manipulate nasal mucosa to minimize postoperative mucosal edema.

journal_name

Acta Otolaryngol

journal_title

Acta oto-laryngologica

authors

Ahn JC,Cho SW,Kim DK,Han DH,Kim DY,Rhee CS,Lee CH,Kim YH,Paek SH,Won TB

doi

10.1080/00016489.2019.1574982

subject

Has Abstract

pub_date

2019-05-01 00:00:00

pages

461-466

issue

5

eissn

0001-6489

issn

1651-2251

journal_volume

139

pub_type

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