Elevated levels of myelin basic protein in CSF in relation to auditory brainstem responses in Bell's palsy.

Abstract:

:Myelin basic protein (MBP) in the cerebrospinal fluid (CSF) was quantified from 28 patients with acute facial palsy. The mean value of MBP in CSF in the study group was 3.4 +/- 0.22 micrograms/l (mean +/- SEM), which was significantly higher than the found in 37 healthy subjects (2.4 +/- 0.13 micrograms/l). Using a 95% confidence interval, 10 patients demonstrated significantly increased CSF concentrations of MBP (greater than 3.95 micrograms/l). Auditory brainstem response (ABR) test showed that 5 patients had abnormal brainstem responses. No significant correlation was observed between elevated MBP in CSF and either pathologic auditory brainstem responses or the clinical degree of the palsy. These results suggest that a brainstem involvement may occur in patients with Bell's palsy. Furthermore, our data accord with previous reports suggesting Bell's palsy to be part of a polyneuropathy.

journal_name

Acta Otolaryngol

journal_title

Acta oto-laryngologica

authors

Edström S,Hanner P,Andersen O,Rosenhall U,Vahlne A,Karlsson B

subject

Has Abstract

pub_date

1987-03-01 00:00:00

pages

198-203

issue

3-4

eissn

0001-6489

issn

1651-2251

journal_volume

103

pub_type

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