Abstract:
:It has already been reported that anaphylatoxin (AT) is closely related to inner ear lesions. In this study the pathology of inner ear damage caused by AT was investigated in Hartley strain and C4 deficient guinea pigs (C4D-GP). Although the biological activity of C3a and C5a is strong, it is of short duration, and the resulting ear damage is considered to be reversible. Because of the cellular degeneration caused by this slight damage, the damage owing to continuously activated C4a is thought to be irreversible, that is, atrophy in the stria vascularis, degeneration and sloughing of the cochlear neurons, and stretching of Reissner's membrane, and C4a is therefore considered to be requisite for the manifestation of inner ear damage.
journal_name
Acta Otolaryngoljournal_title
Acta oto-laryngologicaauthors
Harada T,Sano M,Matsunaga Tdoi
10.1080/00016489.1992.11665416subject
Has Abstractpub_date
1992-01-01 00:00:00pages
265-71issue
2eissn
0001-6489issn
1651-2251journal_volume
112pub_type
杂志文章abstract::The aim of this study was to evaluate the effects of argon laser irradiation of the semicircular canals using computed tomography (CT) images and to examine the basis for laser treatment for benign paroxysmal positional vertigo (BPPV). CT images of the posterior canal were evaluated postoperatively in a patient with i...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489.2011.622292
更新日期:2012-01-01 00:00:00
abstract:OBJECTIVE:We present for the first time evidence that vestibulopathy impairs coordination of the head with the body center of gravity (CG) during free speed gait over ground. Vestibulopathic individuals demonstrate uncoordinated movement and gait due, at least in part, to impaired head stability and visual fixation. Ve...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/003655402000028036
更新日期:2003-01-01 00:00:00
abstract:BACKGROUND AND OBJECTIVE:The aim of this study was to demonstrate the long-term effectiveness of Expansion Sphincter Pharyngoplasty (ESP) as a standalone surgical treatment of obstructive sleep apnea-hypopnea syndrome (OSAHS) patients through a prospective multi-center study. MATERIAL AND METHODS:A prospective non-com...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章,多中心研究
doi:10.1080/00016489.2018.1533992
更新日期:2019-02-01 00:00:00
abstract::The postnatal development of lower stations in the auditory pathway was studied in the guinea pig by recording auditory brainstem potentials. At birth, the brainstem responses of young guinea pigs already have thresholds corresponding to those of adult animals. However, the latencies of the individual potentials are s...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016488409130965
更新日期:1984-01-01 00:00:00
abstract::Primary afferent projections from singular parts of the vestibular labyrinth were studied in the guinea pig. The posterior ampullary nerve, the common trunk of the anterior and lateral ampullary nerves, as well as fibers innervating the macula sacculi or the macula utriculi were traced with crystals of horseradish per...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489209137430
更新日期:1992-01-01 00:00:00
abstract::Merkel cell carcinoma (MCC) is an uncommon cutaneous neoplasm which arises in adults with a peak incidence in the sixth and seventh decades. MCC most often arises in the head and neck area and extremities. Among head and neck primary sites, auricular MCC has proven to be rare and only 20 cases have been reported in th...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章,评审
doi:10.1080/00016480410017503-1
更新日期:2005-02-01 00:00:00
abstract:CONCLUSIONS:Flat-panel cone-beam computed tomography (CBCT) is able to assess the trajectory of the implanted cochlear implant (CI) array. This is essential to determine specific effects of electrode design and surgical innovations on outcomes in cochlear implantation. CBCT is a non-invasive approach yielding similar d...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489.2011.644805
更新日期:2012-04-01 00:00:00
abstract:CONCLUSION:An 18-mer peptide derived from the neurotrophic region of prosaposin (PS-pep) prevents hearing loss and cochlear damage due to transient cochlear ischaemia by activating an anti-apoptotic pathway. PS-pep is a potent candidate molecule for alleviating ischaemia-induced hearing loss. OBJECTIVE:PS-pep was inve...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489.2012.750430
更新日期:2013-05-01 00:00:00
abstract::The sensory and secretory epithelia may become morphologically changed following the exposure to mercury chloride. The earliest and most sever change in the sensory epithelium appeared in the apical part of the cochlea, while the basal coils were only seldom damaged (cytocochleogram studies). Acute intoxication mostly...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016487809111928
更新日期:1978-03-01 00:00:00
abstract::The present paper investigates the hearing function in chronic otitis media vs. tympanoplasty in 41 patients with bilateral chronic otitis media, operated on unilaterally. The auditory evaluation was performed immediately before surgery and at a follow-up time varying from 1 to 14 years (mean = 5 years). Results were ...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489109138410
更新日期:1991-01-01 00:00:00
abstract::The efflux of Na-24 was investigated in isolated labyrinths from a membrane section containing stria vascularis and spiral ligament in artificial endolymph medium. The efflux curves were calculated and compartmental analyses were made. The theoretical possibility of a exchange of sodium between compartments connected ...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016487509121308
更新日期:1975-07-01 00:00:00
abstract::We studied three-dimensional arrangement of collagen fibers and elastic fibers in the human vocal fold by scanning electron microscopy after digesting cellular elements and collagen fibers with formic acid treatment and cellular elements and elastic fibers with 10% sodium hydroxide. The superficial layer consisted of ...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489609137924
更新日期:1996-09-01 00:00:00
abstract::The inner ear distortion induced by gentamicin (GM), a type of aminoglycoside antibiotic, was examined in guinea-pigs. Previous studies which investigated the function of the eighth cranial nerve and organ of Corti using cochlear microphonics (CM) and compound action potential (CAP) reported ototoxicity following expe...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016489850183449
更新日期:1998-06-01 00:00:00
abstract:CONCLUSION:This study demonstrated differential gene expression profiles in salicylate ototoxicity with oligonucleotide microarray. This study may also provide basic information on candidate genes associated with hearing loss and/or tinnitus or recovery after salicylate-induced cochlear dysfunction. OBJECTIVES:Salicyl...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016480600801365
更新日期:2007-05-01 00:00:00
abstract::Acid base balance changes were observed during 72 h following bilateral nasal obstruction in rats. Mouth breathing caused acute respiratory acidosis and marked aerophagia, leading to spontaneous death of the experimental animal 80 to 90 h postoperatively. Stenotic oropharyngeal airway, due to palatal-epiglottic approx...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489109137406
更新日期:1991-01-01 00:00:00
abstract::The facial nerve of the albino rat was compressed by inserting a thin nylon thread in the facial canal. After a survival period of 1-60 days, the animal was perfused with Ringer's solution followed by a 2% periodate-lysine-paraformaldehyde fixative. Frozen sections from the brain stem containing the facial motor nucle...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489409126055
更新日期:1994-05-01 00:00:00
abstract:CONCLUSION:MCT is a useful tool to pre-operatively determine whether internal nasal valve (INV) narrowing affects a nasal obstruction. Functional rhinoplasty seemed to produce better results than septoplasty in Asian patients with a nasal obstruction, due to INV narrowing. OBJECTIVE:This study compared pre-operative m...
journal_title:Acta oto-laryngologica
pub_type: 评论,杂志文章
doi:10.3109/00016489.2015.1108523
更新日期:2016-01-01 00:00:00
abstract::Serial Thermal Vestibulometry with the application of increasing caloric stimuli (corresponding to decreasing temperature of water at successive irrigration of the ears) was performed on normal subjects and patients with lesions in the central nervous system involving the statoacoustic subsystem. The normal values and...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016487909137164
更新日期:1979-01-01 00:00:00
abstract:BACKGROUND:Intratympanic corticosteroid (IC), intravenous batroxobin (IB) as the treatment for sudden sensorineural hearing loss (SSNHL) has been reported. However, the data on combination therapy (CT) was scarce. OBJECTIVE:The aim of this retrospective study was to compare the efficacy of IC, IB, and CT in the treatm...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016489.2019.1592221
更新日期:2019-06-01 00:00:00
abstract:CONCLUSION:Nuclear expression of survivin should be studied as a promising marker of higher-risk laryngeal basaloid squamous cell carcinomas (BSCCs), which can then be treated more aggressively and followed more closely. OBJECTIVE:BSCC is an uncommon bimorphic variant of SCC. The hypothesized greater aggressiveness an...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016480500266685
更新日期:2006-02-01 00:00:00
abstract:CONCLUSION:The endoscopic approaches developed for the treatment of the chordomas according to the different clival location provide the possibility for more complete tumor resection with maximal preservation of anatomic structures and reduction of the overall incidence of complications. OBJECTIVE:The endoscope has re...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016480801995404
更新日期:2009-01-01 00:00:00
abstract:CONCLUSION:Our results suggest that patients with migraine or tension-type headache have subclinical deviations of the subjective visual vertical, which may be associated with their subjective imbalance. OBJECTIVES:Patients affected by migraine or tension-type headache often complain of unsteadiness. However, they rar...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016480802032785
更新日期:2009-01-01 00:00:00
abstract:CONCLUSION:Chances of hearing preservation are better in patients with vestibular schwannoma (VS) from the superior vestibular nerve (SVN) than from the inferior vestibular nerve (IVN). Pathologic posturography and electronystagmography (ENG) findings are more common in schwannomas from the SVN compared with tumors fro...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489.2010.536991
更新日期:2011-05-01 00:00:00
abstract::The vestibulo-ocular reflexes (VORs) were studied in guinea pigs receiving daily administration of aminoglycoside antibiotics. The vestibular epithelia were also examined by scanning electron microscope technique (SEM). The treatment with aminoglycosides led to varying degrees of VORs according to (i) the type of amin...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016488609108622
更新日期:1986-05-01 00:00:00
abstract::Nine subjects with long-term (8-30 years) occupational exposure to industrial solvents and a confirmed diagnosis of psycho-organic syndrome (POS) have been studied with audiological and otoneurological test batteries. The results were compared to a matched control group of nine industrial workers not exposed to solven...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016488909127473
更新日期:1989-01-01 00:00:00
abstract:CONCLUSIONS:The intra-tumoral cytokines IL-6, hepatocyte growth factor (HGF) and tumour necrosis factor-a (TNF-a) stimulate oral cancer cells to enhanced secretion of matrix metalloproteinase (MMP)-1 and -9. These results contribute to an understanding of the extracellular events necessary for tumour progression. OBJE...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016480510027484
更新日期:2005-07-01 00:00:00
abstract::During the period 1967-1985, 95 primary tracheal carcinomas occurred in Finland. The mean annual incidence rate was one per one million inhabitants, the male:female ratio being 7:3. There was a significant increase of the disease by increasing age with the exception of 70-79 years. The most common location was the low...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489109100772
更新日期:1991-01-01 00:00:00
abstract:CONCLUSION:A man-made bone tunnel of 1.5 turns around the modiolus can be created in cases of total cochlear ossification. Patients with ossified cochlea types I and II achieved satisfactory hearing results after cochlear implantation (CI). Patients with ossified cochlea type III, in which the modiolus is damaged by th...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489.2014.947656
更新日期:2014-12-01 00:00:00
abstract:HYPOTHESIS:To examine the cellular events following induced superficial lesions of the human tympanic membrane (TM). Such information could lead to enhanced appreciation of repair mechanisms and novel strategies to restore TM perforations. BACKGROUND:Persistent perforation of the TM in chronic otitis media is a major ...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016489.2017.1321139
更新日期:2017-09-01 00:00:00
abstract:CONCLUSION:The incidence of new cases of Meniere's disease (MD) in elderly patients aged 60 years or more was found to have increased over time after correction for age distribution in the overall population. Job- and care-related fatigue may be involved in the recent increase in elderly-onset cases because physical an...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章,多中心研究
doi:10.1080/00016480802112587
更新日期:2009-02-01 00:00:00