High nuclear expression of the apoptosis inhibitor protein survivin is associated with disease recurrence and poor prognosis in laryngeal basaloid squamous cell carcinoma.

abstract：CONCLUSIONS:A large set of mucin genes is expressed in nasal polyps. The expression pattern is complex and may reflect the wide spectrum of variables involved in polyp formation and progression. Prospective studies including subgroups of nasal polyps and involving substantial numbers of cases in each subgroup will be r...

journal_title：Acta oto-laryngologica

authors： Ali MS,Wilson JA,Bennett M,Pearson JP

更新日期：2005-06-01 00:00:00

abstract：:There is evidence that GABA acts as the excitatory neurotransmitter at synapses between vestibular hair cells and the afferent fibres in the mammalian labyrinth. The question arose as to whether certain vestibular dysfunctions such as labyrinthine vertigo could be treated in patients by influencing the peripheral GABA...

journal_title：Acta oto-laryngologica

authors： Ehrenberger K,Benkoe E,Felix D

更新日期：1982-01-01 00:00:00

abstract：:The nasal mucosa and the autonomic nervous regulation of protective reflexes plays an important role for the protection of the lower airways. Increasing experimental evidence from both animal models and humans suggests that the organization of the autonomic nervous pathways is more complicated than previously assumed....

journal_title：Acta oto-laryngologica

authors： Anggård A

更新日期：1993-05-01 00:00:00

abstract：:Hereditary angioneurotic edema (HAE) is an autosomal dominant disease resulting from a deficiency of functional C1-esterase inhibitor. If not recognized promptly and treated properly the disease can result in a fatal outcome as it causes laryngeal edema, which can lead to a life-threatening acute upper airway obstruct...

journal_title：Acta oto-laryngologica

authors： Lim YC,Kim JK,Shim DB,Lim CH,Jang HJ,Shin HA,Choi EC

更新日期：2005-11-01 00:00:00

abstract：:Several reports indicate that disturbances of the vestibulo-oculomotor ability are a manifestation of the toxic action on the central nervous system exerted by some industrial solvents. The aim of the present investigation was to examine the vestibulo-oculomotor system during exposure to styrene, which is extensively ...

journal_title：Acta oto-laryngologica

authors： Odkvist LM,Larsby B,Tham R,Ahlfeldt H,Andersson B,Eriksson B,Liedgren SR

更新日期：1982-11-01 00:00:00

abstract：CONCLUSION:Surgery remains the preferred option for large vestibular schwannoma (VS). The presence of unpredictable intraoperative difficulties may convince the operator to suspend the surgery to avoid risks to patient life. Additional surgeries may be mandatory and are better performed using a transcochlear approach. ...

journal_title：Acta oto-laryngologica

authors： Kunimoto Y,Lauda L,Falcioni M,Taibah A,Hasegawa K,Sanna M

更新日期：2015-09-01 00:00:00

abstract：:Cochlear blood flow is considered to be closely related to cochlear function. Among several etiologic factors implicated in inner ear diseases, disturbance of local blood flow is held to be one of the most important. With this in view, various pharmaceuticals are currently being used to increase local blood flow in pa...

journal_title：Acta oto-laryngologica

authors： Kawakami M,Makimoto K,Yamamoto H,Takahashi H

更新日期：1992-11-01 00:00:00

abstract：CONCLUSION:Changes in the metabolism of arachidonic acid (AA) might be part of a noise-induced compensatory mechanism with regional specificity. OBJECTIVES:The released imbalance of prostaglandins and leukotrienes, both AA metabolites, might result in altered blood flow regulation in the inner ear and probably contrib...

journal_title：Acta oto-laryngologica

authors： Heinrich UR,Selivanova O,Schmidtmann I,Feltens R,Brieger J,Mann WJ

更新日期：2010-03-01 00:00:00

abstract：:In a previous paper we demonstrated physiologically a sensitive period for acoustic trauma in the rat pup cochlea, with a maximum at 22 days of age. Seven or 60 days after noise exposure these 22-day exposed rats were used for light and electron microscopy. At 7 days, surface preparation revealed restricted damage to ...

journal_title：Acta oto-laryngologica

authors： Lenoir M,Pujol R

更新日期：1980-03-01 00:00:00

abstract：:The fear of destroying an anticipated growth centre has, with time, induced the postponement of nasal septal operations until adult age. Underdevelopment of the nose and middle face is otherwise believed to be the long-term result. In order to test this hypothesis, subepichondrial surgery was performed in growing dome...

journal_title：Acta oto-laryngologica

authors： Freng A,Haye R

更新日期：1985-09-01 00:00:00

abstract：CONCLUSION:The existence of patients with positive non-sentinel node indicates a risk of misdiagnosis of metastasis in oropharyngeal and oral cancer. OBJECTIVES:We attempted to confirm the usefulness of sentinel lymph node biopsy (SLNB) in oropharyngeal and oral cavity cancer to detect clinically occult metastases. P...

journal_title：Acta oto-laryngologica

authors： Santaolalla F,Sanchez JM,Ereño C,Gonzalez A,Rodriguez ML,Sanchez A,Martinez A

更新日期：2008-10-01 00:00:00

abstract：:Two speech processing schemes have been implemented on a real-time laboratory speech processor for speech perception studies on normal-hearing subjects. The first scheme presents the information of two spectral components, the first and second formant of the speech signal, and will be referred to as the ZC (zero-cross...

journal_title：Acta oto-laryngologica

authors： Tong YC,Harrison JM,Huigen J,Clark GM

更新日期：1990-01-01 00:00:00

abstract：CONCLUSION:Our findings suggest that there exists a Na(+) transport system in the cochlea consisting of SGK1, Nedd4 isoforms and ENaC, which may work in concert to transport Na(+) and to maintain homeostasis in the inner ear as they do in other tight epithelia. OBJECTIVES:It has been well demonstrated that the epithel...

journal_title：Acta oto-laryngologica

authors： Zhong SX,Liu ZH

更新日期：2009-09-01 00:00:00

abstract：CONCLUSIONS:The heparin-binding epidermal growth factor-like growth factor (HB-EGF) plays an essential role in the development and invasiveness of cholesteatoma. This study may help to realize the molecular mechanisms underlying the pathogenesis of cholesteatoma and make HB-EGF a promising target for drug intervention ...

journal_title：Acta oto-laryngologica

authors： Xie S,Wang X,Ren H,Liu X,Ren J,Liu W

更新日期：2017-08-01 00:00:00

abstract：:The penetration of oral erythromycin stearate (Abboticin), administered in a dosage of 500 mg three times a day, into the maxillary sinus mucosa and secretion was studied in 15 patients (22 sinuses) operated on for chronic maxillary sinusitis. The average concentration in serum was 2.3 microgram/ml, 1.2 microgram/ml i...

journal_title：Acta oto-laryngologica

authors： Paavolainen M,Kohonen A,Palva T,Renkonen OV

更新日期：1977-09-01 00:00:00

abstract：:The use of SEM as an adjunct to TEM and electrophysiological examination of the cochlea is now well established. It has provided a relatively simple method of assessing the effect of noise, ototoxic drugs, electrical stimulation, etc. on the surface features of the organ of corti. A controlled experiment was undertake...

journal_title：Acta oto-laryngologica

authors： Gleeson MJ

更新日期：1985-11-01 00:00:00

abstract：:Dose-effect curves for inhibition of growth of P388/P mouse lymphoma cells by ethacrynic acid and kanamycin used alone and in combination were determined in vitro. Ethacrynic acid was 600 times more potent than kanamycin and combinations of the drugs resulted in overall additive effects. These results were compared wi...

journal_title：Acta oto-laryngologica

authors： Fox KE,Brummett RE

更新日期：1979-01-01 00:00:00

abstract：:Ciliogenesis events in human vestibular epithelia develop as an asynchronous process between neighbouring cells, but it is a synchronous one within each sensory cell, presenting the following stages. Initially, the cilia buds appear as stubby cylinders well aligned on the cuticular plate of the presumptive sensory cel...

journal_title：Acta oto-laryngologica

authors： Sánchez-Fernández JM,Rivera-Pomar JM

更新日期：1985-03-01 00:00:00

abstract：CONCLUSION:Endolymphatic hydrops could be a reversible inner ear pathological condition. After sac surgery, hydrops was reduced and symptoms went into remission in some cases, although vertigo suppression was not always a result of the reduced hydrops. OBJECTIVE:To examine the changes in endolymphatic hydrops detected...

journal_title：Acta oto-laryngologica

authors： Uno A,Imai T,Watanabe Y,Tanaka H,Kitahara T,Horii A,Kamakura T,Takimoto Y,Osaki Y,Nishiike S,Inohara H

更新日期：2013-09-01 00:00:00

abstract：BACKGROUND:Many patients with coronavirus disease 2019 (COVID-19) complain from olfactory dysfunction (OD). Aims/objectives: To evaluate the prevalence, prognosis, and recovery from OD in COVID-19 patients. MATERIAL AND METHODS:In this study, patients with COVID-19 symptoms who were referred to six different tertiary ...

journal_title：Acta oto-laryngologica

authors： Samimi Ardestani SH,Mohammadi Ardehali M,Rabbani Anari M,Rahmaty B,Erfanian R,Akbari M,Motedayen Z,Samimi Niya F,Aminloo R,Farahbakhsh F,Hosseininasab A,Hassanlouei B,Rezaian N,Mokhtari Z

更新日期：2020-11-11 00:00:00

abstract：:Under constant visual guidance and closed-circuit television monitoring, electrodes are inserted into the fluid spaces of the organ of Corti. The resting electrical potentials are determined with respect to the neutral voltage of the guinea pig and related to other potentials of the auditory labyrinth. The resting pot...

journal_title：Acta oto-laryngologica

authors： Lawrence M

更新日期：1975-03-01 00:00:00

abstract：:Based on a single-chip DSP (TMS320C25, Texas Instruments) a programmable battery-operated sound processor with a digital encoder interface for the Nucleus-22 cochlear implant (CI) was built. The number of quasi-simultaneously addressed electrodes is only limited by the selected pulse width and the maximum rate of stim...

journal_title：Acta oto-laryngologica

authors： Dillier N,Senn C,Schlatter T,Stöckli M,Utzinger U

更新日期：1990-01-01 00:00:00

abstract：CONCLUSIONS:A large series confirmation may suggest elective neck dissection in cN0 MASPIN-negative oral squamous cell carcinomas (SCCs). Re-activated nuclear MASPIN in association with anti-angiogenic or cytotoxic drugs may be extremely effective in the treatment of laryngeal SCC. OBJECTIVES:MASPIN is a serpin showin...

journal_title：Acta oto-laryngologica

authors： Marioni G,Staffieri C,Staffieri A,De Filippis C,Blandamura S

更新日期：2009-05-01 00:00:00

abstract：CONCLUSIONS:The microarray analysis identified 39 genes up- or down-regulated by dexamethasone in the cultured tissue of mice cochlea. Of the eight genes most highly affected, several are suggested to have protective effects in the traumatized inner ear (Fkbp5, Glucocorticoid-induced leucine zipper (Gilz), glutathione ...

journal_title：Acta oto-laryngologica

authors： Maeda Y,Fukushima K,Hirai M,Kariya S,Smith RJ,Nishizaki K

更新日期：2010-12-01 00:00:00

abstract：:In the last few years the use of ABR in the dysmetabolic encephalopathies has aroused considerable interest. Even though brainstem involvement in these syndromes is not yet entirely understood, ABR techniques have provided new and important insights. We studied 60 insulin-dependent diabetic subjects, 29 females and 31...

journal_title：Acta oto-laryngologica

authors： Martini A,Comacchio F,Fedele D,Crepaldi G,Sala O

更新日期：1987-05-01 00:00:00

abstract：CONCLUSION:Glucocorticoid (GC) administration enhanced apoptotic changes in mature olfactory receptor neurons (ORNs). GC administration may enhance regeneration of olfactory epithelium (OE). OBJECTIVES:The mechanism underlying olfactory epithelial cells turnover involves apoptosis replaced by new ORNs. On regeneration...

journal_title：Acta oto-laryngologica

authors： Takanosawa M,Nishino H,Ohta Y,Ichimura K

更新日期：2009-09-01 00:00:00

abstract：:The feasibility of furosemide test for the detection of endolymphatic hydrops has previously been discussed (Authors, 1973, 1975). The glycerol test also has been reported as being effective for the same purpose but only in Meniere patients with fluctuating hearing loss (Klockhoff & Lindblom, 1966). In 48 patients wit...

journal_title：Acta oto-laryngologica

authors： Futaki T,Kitahara M,Morimoto M

更新日期：1977-03-01 00:00:00

abstract：:Explants of basilar papillae from 6-7 days posthatch chicks were cultured in growth medium for a period of 1-8 days. Hair cells were counted following staining of stereocilia bundles with FITC-phalloidin, and the percentage of hair cell survival was determined by comparison to control (i.e. uncultured) specimens. Hair...

journal_title：Acta oto-laryngologica

authors： Frenz DA,Yoo H,Liu W

更新日期：1998-09-01 00:00:00

abstract：OBJECTIVE:To improve the efficacy of intratympanic therapy using perilymphatic entry through the round window membrane. MATERIAL AND METHODS:The perilymphatic entry characteristics of 2 neutral molecules, mannitol (182.2 Da) and inulin (7,000 Da), were studied. A polyethylene catheter was placed in contact with the gu...

journal_title：Acta oto-laryngologica

authors： Chelikh L,Teixeira M,Martin C,Sterkers O,Ferrary E,Couloigner V

更新日期：2003-01-01 00:00:00

abstract：CONCLUSIONS:The presented results add further support to the observation that laser microsurgery is the preferential surgical treatment for recurrent respiratory papillomatosis (RRP). A meticulous follow-up for early recognition of local recurrence and malignant transformation is recommended. OBJECTIVES:Endoscopic mic...

journal_title：Acta oto-laryngologica

authors： Preuss SF,Klussmann JP,Jungehulsing M,Eckel HE,Guntinas-Lichius O,Damm M

更新日期：2007-11-01 00:00:00