Abstract:
:In this study, cytological examination of nasal secretions of 17 patients with cystic fibrosis (CF) was combined with quantitative determination of common inflammatory mediators. Results showed a normal cytogram in these patients. However, obvious mucosal inflammation is evidenced by significantly higher concentrations of leukotriene C4 (LTC4) and eosinophil cationic protein (ECP). The activation of other common inflammatory cells such as mast cells (or basophils) and neutrophils could not be demonstrated since their mediators (histamine, tryptase and myeloperoxidase) are not raised. Increased concentrations of LTC4 and ECP indicate the active participation of eosinophils, and can contribute to the new concept of non-infectious inflammatory involvement of the nasal epithelium of patients with CF.
journal_name
Acta Otolaryngoljournal_title
Acta oto-laryngologicaauthors
Wang D,Brihaye P,Smitz J,De Waele M,Clement Pdoi
10.3109/00016489609137875subject
Has Abstractpub_date
1996-05-01 00:00:00pages
472-6issue
3eissn
0001-6489issn
1651-2251journal_volume
116pub_type
杂志文章abstract:CONCLUSION:L-N-Acetylcysteine (L-NAC) significantly reduced reactive oxygen species (ROS) generation and cochlear cell apoptosis after irradiation. The safe and effective use of L-NAC in reducing radiation-induced sensorineural hearing loss (SNHL) should be verified by further in vivo studies. OBJECTIVES:Radiation-ind...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016480701762490
更新日期:2008-04-01 00:00:00
abstract::The aim of this study was to investigate the influence of weather conditions on the frequency of acute laryngitis in adults. The medical records of 825 patients with a diagnosis of acute laryngitis obtained over a 5-year period were reviewed. Meteorological data reviewed included the daily values of 13 parameters. The...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/000164802320396358
更新日期:2002-09-01 00:00:00
abstract::Multimodality therapy of advanced malignant tumours of the head and neck includes surgery, radiotherapy and chemotherapy. However, the cure rate for these tumours is low and guidelines for the selection and timing of therapy are needed. For such guidelines, tumour cell kinetic parameter studies, e.g. cell proliferatio...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016488309130933
更新日期:1983-01-01 00:00:00
abstract::Background: It has been reported that head-up sleep (HUS) prevents free-floating otoliths from entering canals and that vertical recognition training (VRT) promotes vestibular compensation.Aims/objectives: We would like to assess HUS and VRT for intractable motion-evoked dizziness, including possible benign paroxysmal...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016489.2020.1727566
更新日期:2020-06-01 00:00:00
abstract:CONCLUSION:The data show that the evaluation of obstruction site in patients with obstructive sleep apnea (OSA) should be performed in the sleep state rather than in wakefulness. OBJECTIVE:The aim of this study was to identify correlation between severity of OSA as measured by the apnea-hypopnea index (AHI) and upper ...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489.2010.514007
更新日期:2011-01-01 00:00:00
abstract:OBJECTIVE:Temperature-controlled radiofrequency volumetric tissue reduction (RFVTR) is a minimally invasive technique used in the treatment of the tongue base, soft palate and turbinates. Complications seem to be rare, but the scope of previous studies was often limited by the small number of patients included. The aim...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016480310001385
更新日期:2003-05-01 00:00:00
abstract:CONCLUSION:The results suggest that the beneficial effect of astragaloside IV on impulse noise-induced hearing loss may be due to its ability to inhibit reactive oxygen species (ROS) and prevent apoptosis. OBJECTIVE:Astragaloside IV is the major active constituent of Astragalus membranaceus, which has been widely used...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489.2011.643457
更新日期:2012-05-01 00:00:00
abstract::Background: Betahistine is used worldwide to treat patients with Menière's disease. However, despite it being used for decades, diverging opinions on the effect of betahistine on Menière's symptomatology still exist.Aims: The objective of this systematic review was to provide an overview and rate the certainty of the ...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016489.2020.1777326
更新日期:2020-10-01 00:00:00
abstract::Conclusion Eustachian tube (ET) dysfunction, which plays a role in the pathogenesis chronic suppurative otitis media (CSOM), does not seem to be due to differences in paratubal structures. Objective The aim of this study was to compare the magnetic resonance imaging (MRI) findings of the paratubal structures of the ET...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489.2016.1154187
更新日期:2016-07-01 00:00:00
abstract::The submeningeal approach through the middle cranial fossa to the internal auditory meatus and cerebello-pontine angle after cutting the tentorium cerebelli is described. It is in some way similar to that used by Morrison & King. The approach is achieved by drilling the petrous bone to the level of the compact plate o...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016487509121344
更新日期:1975-11-01 00:00:00
abstract:BACKGROUND:Many patients with coronavirus disease 2019 (COVID-19) complain from olfactory dysfunction (OD). Aims/objectives: To evaluate the prevalence, prognosis, and recovery from OD in COVID-19 patients. MATERIAL AND METHODS:In this study, patients with COVID-19 symptoms who were referred to six different tertiary ...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016489.2020.1836397
更新日期:2020-11-11 00:00:00
abstract::A study was performed to evaluate whether vascular reflex participates in mucosal swelling in nasal allergy, by measuring changes in mucosal swelling in both nasal cavities and changes in blood flow in the bilateral inferior turbinates caused by antigenic challenge in one inferior turbinate. On unilateral challenge, t...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016488209128897
更新日期:1982-07-01 00:00:00
abstract:CONCLUSION:No case of death related to surgery in the form of uvulopalatopharyngoplasty, uvulopalatoplasty or nasal surgery for snoring or sleep apnea has been recorded in Sweden among 4876 patients treated between 1997 and 2005. Severe complications of surgery in the peri- and postoperative period, especially in the f...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489.2010.528793
更新日期:2011-03-01 00:00:00
abstract::In a study on the effects of a frequency-dependent automatic gain control in hearing-aids, two experiments were carried out with hearing-impaired listeners. In the first experiment, the effect of varying the amplitude-frequency response on the speech-reception threshold (SRT) of sentences presented in noise was studie...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016489.1990.12088430
更新日期:1990-01-01 00:00:00
abstract:CONCLUSION:Each of eight patients with bilateral microtia and atresia underwent bilateral reconstruction of the auricles and external auditory canals and were fitted bilateral canal-type hearing aids in the operated ears to replace a bone conduction hearing aid. The ability to discriminate inter-aural intensity differe...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016489.2016.1249947
更新日期:2017-04-01 00:00:00
abstract::Central origin of the vidian nerve in the dog was investigated using the retrograde tracing technique of horseradish peroxidase (HRP). After HRP was applied to the vidian nerve, labelled neurons were found in the medulla oblongata and the geniculate ganglion but could not be found in the trigeminal ganglion. Labelled ...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016488309132883
更新日期:1983-07-01 00:00:00
abstract::Dysphagia is a common presenting complaint in otolaryngology practice, and there are many causes. Forestier syndrome is a rare cause of dysphagia. It is also known as diffuse idiopathic skeletal hyperostosis (DISH) syndrome or vertebral ankylosing hyperostosis. Forestier syndrome consists of anterolateral perivertebra...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016480500504192
更新日期:2006-07-01 00:00:00
abstract::Phoniatric and acoustic examinations were carried out in a group of 30 patients with dysphonia, including 15 with organic type and 15 with functional type. A complex phoniatric assessment offered the possibility to differentiate between these two groups of pathological voices. This was achieved also on the basis of ac...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489109137412
更新日期:1991-01-01 00:00:00
abstract:CONCLUSIONS:The critical stage for cochlear gene regulation in the embryo is E49-E56. These data provide a valuable resource to help elucidate gene regulation in cochlear development and will benefit ear-related studies, especially those that focus on gene and stem cell therapies in hearing loss. OBJECTIVES:To investi...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016489.2017.1341641
更新日期:2017-11-01 00:00:00
abstract:CONCLUSION:This study provides evidence that histamine induced MUC5AC mRNA expression through the activation of the core region of its promoter. It may also help in approaching new therapeutic strategies in airway mucins hypersecretory diseases. OBJECTIVE:Mucin hypersecretion characterizes several respiratory diseases...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489.2015.1017890
更新日期:2015-07-01 00:00:00
abstract::Ciliogenesis events in human vestibular epithelia develop as an asynchronous process between neighbouring cells, but it is a synchronous one within each sensory cell, presenting the following stages. Initially, the cilia buds appear as stubby cylinders well aligned on the cuticular plate of the presumptive sensory cel...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016488509108931
更新日期:1985-03-01 00:00:00
abstract:CONCLUSION:Nitric oxide synthase (NOS) II induction is a protective mechanism against age-related degeneration of the cochlea. OBJECTIVES:An induction of NOS II has been described in different inner ear pathologies. The objective was to examine the role of NOS II in age-related degeneration of the cochlea. METHODS:Th...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016489.2016.1183167
更新日期:2016-10-01 00:00:00
abstract:CONCLUSION:Contrary to our expectation, that the clinical characteristics of temporal bone fracture would differ in children and adults, we found that the two groups were similar. OBJECTIVES:Most studies of temporal bone fractures have been performed in adults. To our knowledge, no study has investigated differences i...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489.2012.754995
更新日期:2013-05-01 00:00:00
abstract::Background: Lermoyez syndrome (LS) is a rare auditory disorder, the details of LS remain unclear.Objectives: To investigate the grades of endolymphatic hydrops (ELH) and clinical characteristics of clinically diagnosed LS.Material and methods: Nine patients with clinically diagnosed LS were included. three-dimensional...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016489.2020.1751275
更新日期:2020-07-01 00:00:00
abstract:OBJECTIVES:Hearing loss after spinal anesthesia has been reported to be related to the transmission of a reduced subarachnoid pressure to the inner ear via the cochlear aqueduct due to loss of spinal fluid. However, there are also some controversies related to this phenomenon, which require systematic investigation. M...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016480410017143
更新日期:2004-12-01 00:00:00
abstract:CONCLUSION:A simple measuring box to determine lip-shift angle and eye-width narrowing offered simultaneous and objective data on outcome dysfunction. The method is as easy as visual approaches. The method is objective and as easy as visual access. It is practical for routine clinical use in any clinic. OBJECTIVES:The...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489.2011.626793
更新日期:2012-01-01 00:00:00
abstract::Thirteen normal subjects were investigated with a broad frequency-band (up to 4.5 Hz) rotatory test. The vestibular stimulation consisted of either a pseudo-random or a sinusoidal frequency sweep oscillation. Eye movements were recorded by EOG. Head movements were recorded either by a potentiometer attached to the cha...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016488409130983
更新日期:1984-03-01 00:00:00
abstract::Voluntary control of the human vestibulo-ocular reflex with and without visual targets was investigated. Subjects were rotated sinusoidally from 0.1 to 1.0 Hz using d.c. electro-oculography to record eye position. The ratio of eye to head movement, or gain, of the vestibulo-ocular reflex was measured. When subjects we...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016487609107490
更新日期:1976-05-01 00:00:00
abstract:CONCLUSION:Cochlear implantation assessment is possible using commercially available standard flat-detector computed tomography (FD-CT) protocols. Image quality is superior to multislice CT (MSCT). The radiation dose of FD-CT is lower in comparison with MSCT standard protocols and may therefore overcome the limitations...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016480903292700
更新日期:2010-04-01 00:00:00
abstract:CONCLUSIONS:We describe a Japanese family with high-frequency sensorineural hearing loss (SNHL) harboring a c.211delC mutation in the KCNQ4 gene. Families showing progressive high-frequency SNHL should be investigated for mutations in the KCNQ4 gene. OBJECTIVE:To determine the responsible deafness gene in a Japanese f...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489.2014.890740
更新日期:2014-06-01 00:00:00