Effects of short inter-stimulus intervals on olfactory and trigeminal event-related potentials.

Abstract:

CONCLUSION:Chemosensory event-related potentials (CSERPs) were identified in all measurements using the 20 s and the 10 s inter-stimulus interval (ISI) protocol, reducing the recording time to 75% or 57% compared with the standard protocol. A possible explanation for the rising CSERP amplitudes by shortening the ISI in CO(2) stimulation is due to a phenomenon known as trigeminal sensitization during repeated stimulation. OBJECTIVES:CSERPs are influenced by the ISI. The aim of this study was to evaluate the changes in CSERPs by decreasing the ISI from 30 s to 20 s or 10 s, respectively. SUBJECTS AND METHODS:Ten normosmic healthy subjects participated this study. Phenyl ethyl alcohol (PEA), hydrogen sulphide (H(2)S) and carbon dioxide (CO(2)) were used in CSERP measurements with different ISI protocols (30 s (standard), 20 s and 10 s). Amplitudes and latencies of ISI protocols were submitted to ANOVA for repeated measurements and t tests for paired samples. RESULTS:The amplitudes of CSERPs with PEA and H(2)S stimuli were decreasing with shortening the ISI significantly. In contrast, the highest amplitudes of trigeminal CSERPs were recorded with the 10 s ISI protocol with CO(2). The ANOVA revealed a significantly different effect of shortening the ISI on CSERPs on the right and the left side.

journal_name

Acta Otolaryngol

journal_title

Acta oto-laryngologica

authors

Kassab A,Schaub F,Vent J,Hüttenbrink KB,Damm M

doi

10.3109/00016480802644605

subject

Has Abstract

pub_date

2009-11-01 00:00:00

pages

1250-6

issue

11

eissn

0001-6489

issn

1651-2251

pii

10.3109/00016480802644605

journal_volume

129

pub_type

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