Differences in innervation and secretory behaviour of two nasal glandular parts in the rat.

Abstract:

:The submucosal glands in the rat nose are characterized by the presence of both neutral and acid glycoproteins, which are important constituents of nasal and tracheobronchial secretions. This study is an attempt to gain a better insight into the secretion of these two types of glycoproteins and its neural regulation. Radiobiochemical experiments show a higher sensitivity to methacholine of the nasal glandular region producing acid glycoproteins than the area secreting neutral glycoproteins. Radioligand receptor binding suggests that the binding parameters of the muscarinic receptors in these two areas are mutually different. Furthermore, rat nasal glandular muscarinic receptors appear to be different from those in smooth muscle of rat ileum.

journal_name

Acta Otolaryngol

journal_title

Acta oto-laryngologica

authors

Klaassen AB,Dooper MW,Rodrigues de Miranda JF,Krabbendam H

doi

10.3109/00016488709128287

subject

Has Abstract

pub_date

1987-11-01 00:00:00

pages

545-51

issue

5-6

eissn

0001-6489

issn

1651-2251

journal_volume

104

pub_type

杂志文章
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