Abstract:
:The submucosal glands in the rat nose are characterized by the presence of both neutral and acid glycoproteins, which are important constituents of nasal and tracheobronchial secretions. This study is an attempt to gain a better insight into the secretion of these two types of glycoproteins and its neural regulation. Radiobiochemical experiments show a higher sensitivity to methacholine of the nasal glandular region producing acid glycoproteins than the area secreting neutral glycoproteins. Radioligand receptor binding suggests that the binding parameters of the muscarinic receptors in these two areas are mutually different. Furthermore, rat nasal glandular muscarinic receptors appear to be different from those in smooth muscle of rat ileum.
journal_name
Acta Otolaryngoljournal_title
Acta oto-laryngologicaauthors
Klaassen AB,Dooper MW,Rodrigues de Miranda JF,Krabbendam Hdoi
10.3109/00016488709128287subject
Has Abstractpub_date
1987-11-01 00:00:00pages
545-51issue
5-6eissn
0001-6489issn
1651-2251journal_volume
104pub_type
杂志文章abstract:BACKGROUND:Endolymphatic sac decompression has shown limited success for the treatment of Ménière's disease (MD). We have published a novel technique with very promising results for the treatment of refractory MD: the Endolymphatic Duct Blockage (EDB) with two titanium clips. One of the challenges of this technique was...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016489.2018.1481524
更新日期:2018-10-01 00:00:00
abstract::The early development of human otoconial membranes was studied by scanning electron microscopy and X-ray microanalysis; 87 specimens, ranging from 7 to 12 weeks gestational age were examined. A few otoconia, which contained calcium, were present in the utricle by the end of the seventh week. By 8 weeks, both the saccu...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016488209128884
更新日期:1982-07-01 00:00:00
abstract:CONCLUSIONS:The facial nerve courses shown by preoperative CT imaging coincide with the surgical findings in most congenital aural atresia cases. CT scanning is critical in evaluation of a patient's candidacy for atresia surgery. OBJECTIVES:To evaluate the diagnostic value of preoperative CT scanning of the facial ner...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016480801953064
更新日期:2008-01-01 00:00:00
abstract::An experimental model of sinusitis in the rabbit was developed, using type 3 pneumococci. The superior parts of the rabbit maxillary sinuses were surgically exposed and the maxillary ostium was unilaterally blocked. The following day a challenge dose of 10(7)-10(9) colony-forming units of Streptococcus pneumoniae, cap...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:
更新日期:1987-05-01 00:00:00
abstract::A case-control design was used to assess eye-head-trunk coordination for community-dwelling elders performing a stand-walk task. Eighteen elders with a high risk of falling were matched to 18 subjects with low risk on the basis of age, living status (living alone or with someone) and category of residence (independent...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016480152583656
更新日期:2001-09-01 00:00:00
abstract:OBJECTIVES:This study was conducted to demonstrate the safety and efficacy of the Otologics Middle Ear Transducer (MET) Ossicular Stimulator and, in particular, to compare the audiologic benefits of this novel form of electromechanical stimulation with those of conventional acoustical amplification. MATERIAL AND METHO...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章,多中心研究
doi:10.1080/00016480410016298
更新日期:2004-05-01 00:00:00
abstract::The gram negative bacteria, nontypable Haemophilus influenzae (NTHi) was used to induce otitis media in a total of 18 chinchillas. Three days post-inoculation, three cohorts of 6 chinchillas each were treated daily for four days with either ceftriaxone, chloramphenicol, or diluent without antibiotics. Middle ear fluid...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489709118000
更新日期:1997-01-01 00:00:00
abstract::In this study, cytological examination of nasal secretions of 17 patients with cystic fibrosis (CF) was combined with quantitative determination of common inflammatory mediators. Results showed a normal cytogram in these patients. However, obvious mucosal inflammation is evidenced by significantly higher concentration...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489609137875
更新日期:1996-05-01 00:00:00
abstract:CONCLUSION:Transforming growth factor β1 gene (TGFβ1) genotype is a potential p16 independent prognostic factor predicting response to chemoradiotherapy in head and neck squamous cell carcinoma (HNSCC). OBJECTIVES:Expression of p16 and epidermal growth factor receptor (EGFR) has been reported to be associated with sur...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489.2012.678944
更新日期:2012-09-01 00:00:00
abstract:CONCLUSION:Candidates for hearing preservation cochlear implant (CI) surgery can be divided into: those who benefit from electrical complement (EC) to remaining hearing and don't require additional amplification, those using a combined electric-acoustic stimulation (EAS) and those with the least amount of residual hear...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016480903567189
更新日期:2010-08-01 00:00:00
abstract::Craniotomy with cerebrospinal fluid (CSF) suction was performed on 18 guinea pigs to determine the effects on the inner ear morphology. Six control animals received anaesthesia only and 12 were operated on with a postoperative survival time of 1 or 24 h. The histologic examinations showed no signs of endolymphatic hyd...
journal_title:Acta oto-laryngologica
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.3109/00016489409126116
更新日期:1994-11-01 00:00:00
abstract:OBJECTIVE:To improve the efficacy of intratympanic therapy using perilymphatic entry through the round window membrane. MATERIAL AND METHODS:The perilymphatic entry characteristics of 2 neutral molecules, mannitol (182.2 Da) and inulin (7,000 Da), were studied. A polyethylene catheter was placed in contact with the gu...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016480310001042
更新日期:2003-01-01 00:00:00
abstract::Abstract Usage of the Vibrant Soundbridge (VSB) with round window (RW)-Coupler placement at the RW has been shown to successfully treat mixed hearing loss. Coupling between the VSB's floating mass transducer (FMT) and the RW membrane is difficult in the case of sclerosis in the RW and drilling down the bony lip unti...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489.2011.649492
更新日期:2012-06-01 00:00:00
abstract::Localization of elements at the cellular and sub-cellular levels was performed with the energy dispersive X-ray microanalysis technique, using shock-frozen, freeze-dried and araldite-embedded mouse (CBA/CBA) cochleae sectioned dry. Anatomical identification occurred in the STEM (scanning transmission electron microsco...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016488409107585
更新日期:1984-11-01 00:00:00
abstract::Unilateral vestibular hypofunction (UVH) is a common vestibular dysfunction. Its influence upon the vestibulospinal reflex (VSR) is studied by posturography. The postural sway is disturbed when the VSR is disregulated because of the UVH. The degree of disturbance depends on the effectivity of the central compensation....
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016488709109046
更新日期:1987-07-01 00:00:00
abstract::In the present study, the protective effect of dexamethasone was analysed following exposure of the cochlea to Pseudomonas aeruginosa Exotoxin A (PaExoA). Four groups of albino Sprague-Dawley rats were used. 20 microl saline was instilled through the tympanic membrane into the round window niche (group A, n = 4); 1 mi...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/000164800750000577
更新日期:2000-03-01 00:00:00
abstract::Eight patients with dystrophia myotonica (Steinert) were studied. They all had myotonia and pathological EMG and in some cases other signs of the disease. The 50% relaxation times of the stapedius reflex were significantly prolonged compared with a control group of 40 healthy, young subjects with normal hearing and no...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016488209128937
更新日期:1982-11-01 00:00:00
abstract::Intense sound stimulation may result in excessive glutamate release from the inner hair cells, resulting in binding to the postsynaptic glutamate receptors and leading to neuronal degeneration and functional impairment. In this study we investigated the therapeutic effect and time window of caroverine, an N-methyl-D-a...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016480310000638
更新日期:2003-10-01 00:00:00
abstract::In a retrospective study of 475 patients suffering from Meniere's disease, the hearing loss, both in the low and high frequencies, and the loss of vestibular function were studied over time. There were large variations of hearing loss from case to case but, overall, the low were more affected than the high frequencies...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489609137819
更新日期:1996-03-01 00:00:00
abstract::Background: Intratympanic and intravenous gadolinium administration is used to visualise endolymphatic hydrops. Aims/objectives: The goal of this study was to compare the image quality between intratympanic (IT-method) and intravenous (IV-method) gadolinium administration using three-dimensional inversion recovery wit...
journal_title:Acta oto-laryngologica
pub_type: 临床试验,杂志文章
doi:10.1080/00016489.2019.1600719
更新日期:2019-08-01 00:00:00
abstract::It is well documented that quinine induces reversible hearing loss and tinnitus. The purpose in this study was to induce a quinine hearing loss and to investigate if verapamil, a Ca2+ channel antagonist of L-type might affect the response. Pigmented guinea pigs (n = 24) were anaesthetized by atropine. Hypnorm and mida...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489709117990
更新日期:1997-01-01 00:00:00
abstract:CONCLUSIONS:Patients with sudden hearing loss and dizziness after barotrauma should be suspected of barotraumatic perilymph fistula (PLF). Early surgical repair of PLF showed better hearing outcomes. Therefore, diagnostic criteria should help surgical indications of barotraumatic PLF. OBJECTIVES:The aim of this study ...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016489.2016.1213419
更新日期:2017-01-01 00:00:00
abstract::Several reports have indicated that some cochlear implant patients experience a reduction in their tinnitus while listening to noise or speech. In the present study, two patients reporting bilateral tinnitus were selected from a group of adults with the Nucleus cochlear implant. They rated their tinnitus loudness and ...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489309135811
更新日期:1993-05-01 00:00:00
abstract:CONCLUSIONS:The results of this study confirm that both smoking of tobacco and alcohol consumption are risk factors for oral and oropharyngeal squamous cell carcinoma (OOSCC). The use of moist snuff had no effect on the risk of OOSCC, probably due to the low levels of tobacco-specific N-nitrosamines in Swedish moist sn...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016480510043440
更新日期:2005-09-01 00:00:00
abstract:CONCLUSION:Moxifloxacin was generally well tolerated and highly effective in the treatment of acute bacterial rhinosinusitis (ABS). The incidence of adverse events (AEs) and adverse drug reactions (ADRs) was low. The effectiveness, safety, and tolerability information collected in this study confirm the clinical safety...
journal_title:Acta oto-laryngologica
pub_type: 临床试验,杂志文章,多中心研究
doi:10.3109/00016481003629036
更新日期:2010-09-01 00:00:00
abstract:CONCLUSION:The degree of contrast enhancement of the cochlea after intratympanic administration of meglumine gadopentetate (Gd-DTPA) or gadodiamide hydrate (Gd-DTPA-BMA) varies widely among patients with inner ear diseases. There was no morphological change in the stria vascularis after Gd-DTPA or Gd-DTPA-BMA was place...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489.2010.507781
更新日期:2011-02-01 00:00:00
abstract:OBJECTIVE:Ischemic vascular damage of the inner ear is one of the known causes of sensorineural sudden hearing loss (SSHL). Folate is an emerging risk factor associated with an increased risk of vascular damage. The aim of this study was to investigate whether low serum folate levels are associated with SSHL. MATERIAL...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016480410016216
更新日期:2004-06-01 00:00:00
abstract::ESS is a form of minimal access surgery that includes different tasks and manoeuvres requiring sophisticated psychomotor coordination with varying levels of force application. The avoidance of complications is partially dependent upon reducing surgical force application when operating against vital barriers such as th...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016480410016568
更新日期:2004-03-01 00:00:00
abstract:CONCLUSION:The Esteem(®) device proved to offer beneficial results in subjects suffering from high frequency, severe bilateral sensorineural hearing loss (SNHL) and may be considered as an alternative procedure to conventional hearing aids (HAs) or electroacoustic stimulation (EAS) systems. OBJECTIVES:Since the Esteem...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489.2010.536994
更新日期:2011-04-01 00:00:00
abstract:CONCLUSION:The data show that the evaluation of obstruction site in patients with obstructive sleep apnea (OSA) should be performed in the sleep state rather than in wakefulness. OBJECTIVE:The aim of this study was to identify correlation between severity of OSA as measured by the apnea-hypopnea index (AHI) and upper ...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489.2010.514007
更新日期:2011-01-01 00:00:00