Low serum folate levels: a risk factor for sudden sensorineural hearing loss?

Abstract:

OBJECTIVE:Ischemic vascular damage of the inner ear is one of the known causes of sensorineural sudden hearing loss (SSHL). Folate is an emerging risk factor associated with an increased risk of vascular damage. The aim of this study was to investigate whether low serum folate levels are associated with SSHL. MATERIAL AND METHODS:Serum folate levels were determined in 43 patients with SSHL and in 24 controls. RESULTS:Folate levels were found to be significantly lower in SSHL patients than in controls (mean difference -1.96 ng/ml; 95% CI -3.31, -0.59 ng/ml; p = 0.006). No significant relationship between folate levels and either sex, age, cigarette smoking, alcohol consumption or hypertension was observed, while a significant relationship was found between low folate levels and high homocysteine (HCY) levels in all 43 patients (p < 0.01). The potential influence of low folate levels on hearing impairment in SSHL patients can be explained by the effects on HCY metabolism and the diminution of folate antioxidant capacity. CONCLUSION:Further studies are needed to elucidate whether low folate levels can be considered a risk factor for SSHL.

journal_name

Acta Otolaryngol

journal_title

Acta oto-laryngologica

authors

Cadoni G,Agostino S,Scipione S,Galli J

doi

10.1080/00016480410016216

subject

Has Abstract

pub_date

2004-06-01 00:00:00

pages

608-11

issue

5

eissn

0001-6489

issn

1651-2251

journal_volume

124

pub_type

杂志文章
  • Laryngeal abductor muscle reinnervation in a pig model.

    abstract:OBJECTIVE:To develop a large animal model for studies of laryngeal abductor reinnervation. MATERIAL AND METHODS:Six minipigs underwent unilateral anastomosis of the phrenic nerve-abductor branch of the recurrent laryngeal nerve (RLN). Polyhydroxybutyrate (PHB) conduits were used for repair. At each of 30, 60 and 120 d...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.1080/00016480410022507

    authors: Birchall M,Idowu B,Murison P,Jones A,Burt R,Ayling S,Stokes C,Pope L,Terenghi G

    更新日期:2004-09-01 00:00:00

  • Head-body righting reflex from the supine position and preparatory eye movements.

    abstract:CONCLUSION:Saccular and utricular maculae can provide information on the supine static position, considering that both have pronounced curved structures with hair cells having a variety of polarization vectors that enable them to sense an inverted position and thus direct the righting reflex. OBJECTIVE:The vestibular ...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.1080/00016480510036448

    authors: Troiani D,Ferraresi A,Manni E

    更新日期:2005-05-01 00:00:00

  • Spontaneous otogenic pneumocephalus.

    abstract::The diagnosis and management of spontaneous otogenic pneumocephalus with literature review is described. A young sportsman experienced headache and fluctuating mass in his occiput during increased physical activity. A large extradural intracranial pneumocephalus with corresponding emphysema was imaged on a CT scan. Tr...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章,评审

    doi:10.3109/00016489.2010.541941

    authors: Mohammed el R,Profant M

    更新日期:2011-06-01 00:00:00

  • Electric stimulation complements functional residual hearing in partial deafness.

    abstract:CONCLUSION:Candidates for hearing preservation cochlear implant (CI) surgery can be divided into: those who benefit from electrical complement (EC) to remaining hearing and don't require additional amplification, those using a combined electric-acoustic stimulation (EAS) and those with the least amount of residual hear...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.3109/00016480903567189

    authors: Podskarbi-Fayette R,Pilka A,Skarzynski H

    更新日期:2010-08-01 00:00:00

  • Concurrent chemoradiotherapy with carboplatin and uracil-f tegafur (UFT) for patients with poor performance status with locally advanced squamous cell carcinoma of the head and neck (SCCHN).

    abstract:CONCLUSIONS:Concurrent chemoradiotherapy with carboplatin and uracil-f tegafur (UFT) seems to be a promising and appropriate regimen for patients with poor performance status (PS) with locally advanced squamous cell carcinoma of the head and neck (SCCHN). OBJECTIVE:We designed a regimen based on divided low-dose admin...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章,随机对照试验

    doi:10.1080/00016480701200251

    authors: Katori H,Tsukuda M,Taguchi T

    更新日期:2007-10-01 00:00:00

  • The rebound phenomenon of glycerol-induced changes in the endolymphatic space.

    abstract::Volumetric changes of the scala media were histologically investigated in normal guinea pigs to see whether glycerol-induced volumetric change of the scala media followed a biphasic course similar to the auditory threshold in the glycerol test. Glycerol was administered orally in a 12 ml/kg dose. The volume of the sca...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.1080/00016489950181369

    authors: Takeda T,Takeda S,Saito H,Hamada M,Sawada S

    更新日期:1999-01-01 00:00:00

  • Clinical trial on tinnitus patients with normal to mild hearing loss: broad band noise and mixed pure tones sound therapy.

    abstract:BACKGROUND:Tinnitus treatments present a quandary for clinicians, but no thoroughly satisfactory medical treatments are offered to tinnitus patients. OBJECTIVE:We compared sound therapy effects of the broad band noise (BBN) and the mixed pure tones on tinnitus patients with normal to mild hearing loss, and the possibl...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章,随机对照试验

    doi:10.1080/00016489.2019.1575522

    authors: Li Y,Feng G,Wu H,Gao Z

    更新日期:2019-03-01 00:00:00

  • Lateralization of horizontal semicircular canal benign paroxysmal positional vertigo (HSC-BPPV) with the latency test: a pilot study.

    abstract::Background: The treatments of horizontal semicircular canal benign paroxysmal positional vertigo (HSC-BPPV) have low remission rates ranging between 60% and 90%, connected to the difficulty in correctly identifying the affected side of HSC-BPPV. Objective: To propose and compare the efficacy of the latency test (LT) i...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.1080/00016489.2019.1635712

    authors: Scarpa A,Cassandro C,Gioacchini FM,Viola P,Cuofano R,Kaleci S,Ralli M,Chiarella G,Cassandro E

    更新日期:2019-10-01 00:00:00

  • Auditory potentials in profoundly deaf subjects.

    abstract::In 12 healthy volunteers, and 5 prelingually and 5 postlingually profoundly deaf subjects, a 500 Hz filtered click stimulus was applied to the mastoid via the bone conductor. In all the healthy volunteers, middle latency response (MLR) was recorded. Among all profoundly deaf subjects, MLR was recorded only in 2 with p...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.3109/00016488509108929

    authors: Ribarić K,Padovan I,Prevec TS

    更新日期:1985-03-01 00:00:00

  • The long-term effect of bilateral inferior colliculus ablation on auditory brainstem response in awake cats.

    abstract::In this study auditory brainstem responses (ABRs) were recorded repeatedly in three awake cats before and after bilateral aspiration of the inferior colliculi (ICs). All surgical procedures were performed under anaesthesia with Nembutal. Postoperative recordings were obtained 1 week, 3 months, 8 months and 13 months a...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.1080/00016489950181503

    authors: Kaga K,Yamada K,Tsuzuku T,Uno A

    更新日期:1999-03-01 00:00:00

  • The relationship between vasomotor symptoms and menopause-associated dizziness.

    abstract:CONCLUSION:Vasomotor symptoms (VMS) and especially hot flushes are negatively associated with recovery from menopause-related dizziness. A further study is justified to determine whether hormone replacement therapy (HRT) can shorten this recovery time. OBJECTIVES:This study aimed to compare the rate of recovery from d...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.3109/00016489.2013.841991

    authors: Owada S,Suzuki M

    更新日期:2014-02-01 00:00:00

  • Comparative ototoxicity of furosemide and piretanide.

    abstract::The purpose of these studies was to compare the ototoxicity of piretanide to that of furosemide in the chinchilla. Chinchillas weighing 400 to 700 g were anesthetized with ketamine plus pentobarbital. Endocochlear potential (EP) was measured continuously by the round window approach using glass microelectrodes. Pireta...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.3109/00016488609108608

    authors: Rybak LP,Whitworth C

    更新日期:1986-01-01 00:00:00

  • Noise exposure alters cyclooxygenase 1 (COX-1) and 5-lipoxygenase (5-LO) expression in the guinea pig cochlea.

    abstract:CONCLUSION:Changes in the metabolism of arachidonic acid (AA) might be part of a noise-induced compensatory mechanism with regional specificity. OBJECTIVES:The released imbalance of prostaglandins and leukotrienes, both AA metabolites, might result in altered blood flow regulation in the inner ear and probably contrib...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.1080/00016480903168066

    authors: Heinrich UR,Selivanova O,Schmidtmann I,Feltens R,Brieger J,Mann WJ

    更新日期:2010-03-01 00:00:00

  • Hoarseness and misdirected swallowing before and after antireflux surgery.

    abstract:CONCLUSION:Patients with hiatus hernia can be relieved from H, MSL and MSN by hiatus hernia repair. OBJECTIVE:It has been hypothesized that respiratory symptoms in patients with gastro-oesophageal reflux disease (GORD) may, in some cases, be due to misdirected swallowing as a consequence of defective opening of the up...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.1080/00016480410017945

    authors: Mjönes AB,Ledin T,Grahn LT,Hultcrantz E

    更新日期:2005-01-01 00:00:00

  • Dynamic upper airway changes during sleep in patients with obstructive sleep apnea syndrome.

    abstract:CONCLUSION:The narrowing pattern of the upper airway in obstructive sleep apnea patients may be different in sleep as compared with awake. Three different types of obstruction were observed in these subjects during drug-induced sleep. The different obstruction pattern during drug-induced sleep suggests that different s...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.3109/00016480902780242

    authors: Chuang LP,Chen NH,Li HY,Lin SW,Chou YT,Wang CJ,Liao YF,Tsai YH

    更新日期:2009-12-01 00:00:00

  • Correlation between severity of sleep apnea and upper airway morphology: Cephalometry and MD-CT study during awake and sleep states.

    abstract:CONCLUSION:The data show that the evaluation of obstruction site in patients with obstructive sleep apnea (OSA) should be performed in the sleep state rather than in wakefulness. OBJECTIVE:The aim of this study was to identify correlation between severity of OSA as measured by the apnea-hypopnea index (AHI) and upper ...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.3109/00016489.2010.514007

    authors: Heo JY,Kim JS

    更新日期:2011-01-01 00:00:00

  • The use of Preyer's reflex in evaluation of hearing in mice.

    abstract::Preyer's reflex, the elicitation of startle response to auditory stimuli, has been widely used for the evaluation of hearing in rodents and other animals. Surprisingly, however, the sensitivity and specificity of Preyer's reflex in the assessment of hearing has not been adequately studied. The aim of this study was to...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:

    authors: Jero J,Coling DE,Lalwani AK

    更新日期:2001-07-01 00:00:00

  • Cochlear implantation surgery without posterior tympanotomy: can we still improve it?

    abstract:CONCLUSION:The amendments made to pre-existing transcanal approaches limit the possibility of extrusion of the electrode and reduce the time of 'blind' surgery. OBJECTIVE:Alternative techniques to classic mastoidectomy and posterior tympanotomy for cochlear implantation have already been described but their main drawb...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.3109/00016480902998299

    authors: Guevara N,Bailleux S,Santini J,Castillo L,Gahide I

    更新日期:2010-01-01 00:00:00

  • Vestibular morphology in relation to age and circling behavior.

    abstract::The DBA/2 strain of mice have genetically induced vestibular dysfunction that presents grossly at an early age as circling behavior and abnormal righting reflexes. The vestibular morphology of this strain has not previously been examined. DBA/2 mice of different ages that showed circling behavior were sacrificed and t...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.3109/00016489409126075

    authors: Bloom D,Hultcrantz M

    更新日期:1994-07-01 00:00:00

  • Effects of chronic exposure to electromagnetic waves on the auditory system.

    abstract:CONCLUSION:The results support that chronic electromagnetic field exposure may cause damage by leading to neuronal degeneration of the auditory system. OBJECTIVES:Numerous researches have been done about the risks of exposure to the electromagnetic fields that occur during the use of these devices, especially the effe...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.3109/00016489.2015.1032434

    authors: Özgür A,Tümkaya L,Terzi S,Kalkan Y,Erdivanlı ÖÇ,Dursun E

    更新日期:2015-08-01 00:00:00

  • Evaluation of functional rhinoplasty using the Modified Cottle test in Asian patients.

    abstract:CONCLUSION:MCT is a useful tool to pre-operatively determine whether internal nasal valve (INV) narrowing affects a nasal obstruction. Functional rhinoplasty seemed to produce better results than septoplasty in Asian patients with a nasal obstruction, due to INV narrowing. OBJECTIVE:This study compared pre-operative m...

    journal_title:Acta oto-laryngologica

    pub_type: 评论,杂志文章

    doi:10.3109/00016489.2015.1108523

    authors: Kwun C,Yang CW,Kim SW,Lee KH

    更新日期:2016-01-01 00:00:00

  • House-Brackmann and Yanagihara grading scores in relation to electroneurographic results in the time course of Bell's palsy.

    abstract::The results of House Brackmann and Yanagihara grading were compared with electroneurographic (ENoG) data in 30 consecutive patients with Bell's palsy. The examinations were made on mean days 11, 36 and 99. Twenty-four patients had a favourable outcome (Yanagihara > or = 36 at three months). Based on our observations, ...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.1080/00016489850182440

    authors: Engström M,Jonsson L,Grindlund M,Stålberg E

    更新日期:1998-11-01 00:00:00

  • Acoustic cues underlying auditory distance in barn owls.

    abstract:CONCLUSIONS:We conclude that: (1) among several cues examined, the monaural cue of direct-to-reverberant (D/R) ratio in the ipsilateral ear provides the most information about sound-source distance; (2) interaural level difference (ILD) provides less information about sound-source distance; and (3) a comprehensive theo...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.1080/00016480701840114

    authors: Kim DO,Moiseff A,Turner JB,Gull J

    更新日期:2008-04-01 00:00:00

  • Assessment of vestibular function of infants and children with congenital and acquired deafness using the ice-water caloric test, rotational chair test and vestibular-evoked myogenic potential recording.

    abstract:CONCLUSIONS:The vestibular function can be assessed by ice-water caloric test, rotational chair test and VEMP recording in severely hearing impaired infants and young children, and 85% of these patients showed abnormal responses in these tests. OBJECTIVES:To evaluate the vestibular function of infants and young childr...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.1080/00016480601002039

    authors: Shinjo Y,Jin Y,Kaga K

    更新日期:2007-07-01 00:00:00

  • Expression of transient receptor potential channel melastin (TRPM) 1-8 and TRPA1 (ankyrin) in mouse inner ear.

    abstract:CONCLUSIONS:It has been shown that TRPMs may play a functional role in sensory cell physiology, fluid homeostasis, sensory cell death, and thermosensation in the inner ear, while TRPA1 plays an important role in sensory transduction. OBJECTIVE:To study expression of TRPM1-8 and TRPA1 in the mouse inner ear. MATERIALS...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.1080/00016480802570545

    authors: Takumida M,Ishibashi T,Hamamoto T,Hirakawa K,Anniko M

    更新日期:2009-10-01 00:00:00

  • Direction of lateral traction in Ejnell's technique: an experimental study and case report of bilateral vocal cord paralysis.

    abstract::In order to develop the method of laterofixation of the vocal cord (Ejnell's method) in cases of bilateral vocal cord paralysis, six autopsy specimens of normal larynx were obtained. We inserted traction sutures under conditions of direct visualization and studied the relationship between the direction of the traction...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.1080/00016480260000120

    authors: Tamura E,Kitahara S,Ogura M,Hiroi S

    更新日期:2002-06-01 00:00:00

  • Proteomic analysis of cholesteatoma.

    abstract:OBJECTIVE:Proteomic analysis with 2D electrophoresis and matrix-assisted laser desorption and ionization time-of-flight mass spectrometry (MALDI-TOF MS) may be a powerful tool for identifying and characterizing the specific proteins relating to the pathogenesis of some diseases, including cholesteatoma. The purpose of ...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.1080/00016480410017882

    authors: Kim JL,Jung HH

    更新日期:2004-09-01 00:00:00

  • Hearing in patients operated unilaterally for otosclerosis. Self-assessment of hearing and audiometric results.

    abstract::The objective of this study was to examine the outcome of unilateral stapes surgery in one patient group with bilateral hearing loss and one group with unilateral hearing loss. The patients' own estimations of improvement in hearing ability and the occurrence of other ear-related symptoms were examined retrospectively...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.1080/00016489950180982

    authors: Lundman L,Mendel L,Bagger-Sjöbäck D,Rosenhall U

    更新日期:1999-01-01 00:00:00

  • Cross-coupling between horizontal and vertical eye movements during optokinetic nystagmus and optokinetic afternystagmus elicited in microgravity.

    abstract::The occurrence of horizontal jerks with larger amplitudes than on Earth was observed during vertical optokinetic nystagmus in astronauts tested throughout a 7-day spaceflight. During early exposure to microgravity, a horizontal spontaneous-like nystagmus was recorded in darkness following both vertical and horizontal ...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.3109/00016489009107432

    authors: Clement G,Berthoz A

    更新日期:1990-03-01 00:00:00

  • Cochlear Implants in Special Cases: Deafness in the Presence of Disabilities and/or Associated Problems.

    abstract::The aim of the present study is to construct a reference model with the indication for the attitude, the requirements and the resources needed in order to be able to deal with deafness in the presence of disabilities or associated problems. The study group consisted of 13 adults and 18 children affected by profound de...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.1080/03655230410017193

    authors: Filipo,Bosco,Mancini,Ballantyne

    更新日期:2004-04-01 00:00:00