Correlation between severity of sleep apnea and upper airway morphology: Cephalometry and MD-CT study during awake and sleep states.

Abstract:

CONCLUSION:The data show that the evaluation of obstruction site in patients with obstructive sleep apnea (OSA) should be performed in the sleep state rather than in wakefulness. OBJECTIVE:The aim of this study was to identify correlation between severity of OSA as measured by the apnea-hypopnea index (AHI) and upper airway morphology examined by cephalometry and dynamic multidetector computed tomography (MD-CT) in awake and sleep states. METHODS:Polysomnography and cephalometry were performed in 94 patients with snoring or OSA. Among them, 64 patients underwent MD-CT study. Thirteen cephalometric variables were measured. We analyzed the correlations between AHI and MD-CT measurements - minimal cross-sectional area (mCSA) and collapsibility index (CI) in high retropalate (HRP), low retropalate (LRP), high retroglossal (HRG), and low retroglossal (LRG) areas. RESULTS:Statistically significant correlations between the AHI and inferior displacement of the hyoid bone and pharyngeal length were identified in the cephalometric study. In wakefulness, AHI had a negative correlation with mCSA in the LRP area and a significant correlation with CI in LRP and HRG in MD-CT measurements. However, in the sleep state, the AHI had a negative correlation with mCSA in LRP, HRG, and LRG areas and a meaningful correlation with CI for the whole upper airway (HRP, LRP, HRG, and LRG).

journal_name

Acta Otolaryngol

journal_title

Acta oto-laryngologica

authors

Heo JY,Kim JS

doi

10.3109/00016489.2010.514007

subject

Has Abstract

pub_date

2011-01-01 00:00:00

pages

84-90

issue

1

eissn

0001-6489

issn

1651-2251

journal_volume

131

pub_type

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