Abstract:
OBJECTIVE:To ascertain whether a daily nasal spray with physiological saline could prevent symptoms of common cold in a population of otherwise healthy adults. MATERIAL AND METHODS:This was study involving 10 weeks of daily use of a nasal saline spray and 10 weeks of only recording symptoms. Young adults eligible for military service at an army barrack in Boden, Sweden were invited to participate in the study and 108 healthy conscripts aged approximately 20 years agreed to do so. Data were recorded by the participants in a diary at home. In the diary the participants noted symptoms such as rhinitis, blocked nose, cough, fever and sore throat (pharyngeal pain). They also recorded inability to perform their duties due to the symptoms, and any medication or antibiotics necessitated by upper respiratory tract infection. RESULTS:A total of 69 subjects completed the 20-week diary period. For 60 of them, compliance during the spray period exceeded 60% and their data were used in the statistical calculations. During the spray period the number of days with nasal secretion and/or blocked nose (mean 6.4 days) was significantly (p=0.027) lower than that during the observation period (mean 11 days). Furthermore, the participants had a mean of 0.7 episodes of upper respiratory tract infection during the spray period, compared with 1.0 episodes during the observation period (p=0.05). CONCLUSION:A daily nasal spray with saline can prevent nasal symptoms of common cold in a population of otherwise healthy adults.
journal_name
Acta Otolaryngoljournal_title
Acta oto-laryngologicaauthors
Tano L,Tano Kdoi
10.1080/00016480410017657subject
Has Abstractpub_date
2004-11-01 00:00:00pages
1059-62issue
9eissn
0001-6489issn
1651-2251pii
MEPLNPKE7C69KUJCjournal_volume
124pub_type
临床试验,杂志文章,随机对照试验abstract::The electromagnetic interference of the recently introduced bone-anchored hearing aid (BAHA) model "BAHA Compact" by digital cellular phones is investigated and compared with that of the older "BAHA Classic 300" model. Measurements with two different digital cellular phones in a laboratory setting indicated that the n...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016480260092318
更新日期:2002-07-01 00:00:00
abstract:OBJECTIVES:In this paper we test the concept of combining electrical stimulation for high-frequency sound with acoustic hearing for low-frequency information in the same ear. In addition, we test whether residual hearing can be preserved when an electrode is placed up to 10 mm into the inner ear, and whether the site o...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016480410016423
更新日期:2004-05-01 00:00:00
abstract:BACKGROUND:Oropharyngeal squamous cell carcinoma (OPSCC) positive for human papillomavirus (HPV) increases wolrd wide. AIMS/OBJECTIVES:The objective for this study has been to evaluate tumor phenotypes and tumor host responses with respect to five-year disease-specific survival (DSS) in HPV(+) and HPV(-) patients. MA...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016489.2018.1497809
更新日期:2018-11-01 00:00:00
abstract::Background: Various graft materials and surgical methods are used in the treatment of tympanic membrane perforations.Aims/Objectives: The aim of this study was to evaluate the operation method and graft success of extended perichondrial butterfly myringoplasty performed by an endoscopic method and the hearing gain of ...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016489.2020.1730949
更新日期:2020-04-01 00:00:00
abstract::Seventeen cases of postinflammatory acquired artresia of the external auditory canal in 14 women are described and analysed. Fourteen of these cases were solid atresias in which the auditory canal was more or less filled with fibrous tissue. Three patients had partial membranous atresia. The aetiology was external oti...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016487509124663
更新日期:1975-01-01 00:00:00
abstract::In 4 cases of Meniere's disease, E.P., concentrations of Na, K, Cl, and protein, and osmolality were determined in endolymph from the basal coil of the cochlea. In 3 cases, endolymph was found normal in nature as compared with normal animals. In one long-standing (11 years) case, a strial dysfunction was evidenced. In...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016488409132935
更新日期:1984-05-01 00:00:00
abstract::An antimicrobial agent, kanamycin, has been shown to produce as an untoward effect, ototoxicity. The purpose of this study was to investigate differential effects of kanamycin ototoxicity as a function of Rx timing with regard to circadian rhythms. Four groups of comparable weight Sprague-Dawley rats received a daily ...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489109100749
更新日期:1991-01-01 00:00:00
abstract::Beta 2-microglobulin (beta 2m) is a small polypeptide, related to the immunoglobulins and present on nucleated cells as part of the strong transplantation antigens. Elevated plasma levels have been recorded in patients with various malignant diseases. Human beta 2m has also been detected immunohistochemically in carci...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016488409107571
更新日期:1984-09-01 00:00:00
abstract:CONCLUSION:Contrast enhancement of the inner ear by three-dimensional fluid-attenuated inversion recovery magnetic resonance imaging (3D-FLAIR MRI) taken 4 h after intravenous gadolinium (Gd) injection was better than when taken at 10 min. Using heavily T2-weighted 3D-FLAIR MRI, visualization of endolymphatic hydrops (...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489.2011.639085
更新日期:2012-03-01 00:00:00
abstract::It has already been reported that anaphylatoxin (AT) is closely related to inner ear lesions. In this study the pathology of inner ear damage caused by AT was investigated in Hartley strain and C4 deficient guinea pigs (C4D-GP). Although the biological activity of C3a and C5a is strong, it is of short duration, and th...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016489.1992.11665416
更新日期:1992-01-01 00:00:00
abstract:CONCLUSION:Idiopathic otolithic vertigo (IOV) with relatively long duration of attacks might be caused by endolymphatic hydrops in the otolith organ. OBJECTIVES:To clarify the pathophysiology underlying IOV, episodic tilting or translational sensation attacks by unknown causes, especially the possibility of endolympha...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489.2015.1022834
更新日期:2015-01-01 00:00:00
abstract::Nontypeable Haemophilus influenzae (NTHi) lipooligosaccharide, the major component of H. influenzae endotoxin, was localized in the middle and inner ear subsequent to the resolution of experimental otitis media induced by this pathogen. A monoclonal antibody specific for the lipooligosaccharide of this strain was used...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016489950180838
更新日期:1999-01-01 00:00:00
abstract:CONCLUSION:This study shows that, in cochlear implantation (CI) surgery, pre-operative caloric test results are not correlated with post-operative outcomes of dizziness or speech perception. OBJECTIVES:To determine the role of pre-operative caloric tests in CI. METHODS:The records of 95 patients who underwent unilate...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489.2016.1172731
更新日期:2016-09-01 00:00:00
abstract:CONCLUSION:The increased AQP5 expression associated with ageing in glands, which mainly secreted a serous solution, suggests a compensation for the decreased amount of saliva secretion associated with age progression. OBJECTIVE:To investigate the change in aquaporin-1 (AQP1) and aquaporin-5 (AQP5) expression in the sa...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489.2016.1165353
更新日期:2016-09-01 00:00:00
abstract::Microsurgery of the facial nerve has resulted in a great progress by regaining, thanks to its various techniques, not only the voluntary movements of the face but in addition also the emotional expressive motility. It has become evident, however, that one disadvantage is always unavoidable even in the most subtle reco...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016488109138533
更新日期:1981-05-01 00:00:00
abstract::The influence of posture on nasal cavity geometry was studied by acoustic rhinometry in 14 normal adult subjects. On adopting a supine position from sitting the volume of the initially more patulous nasal cavity decreased and the volume of the less patulous side increased. These changes in volume are statistically sig...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489309135858
更新日期:1993-07-01 00:00:00
abstract:CONCLUSION:The results of this study suggest that treatment with radical scavengers has the potential to become an effective new therapy for age-related hearing loss. OBJECTIVE:To assess the efficacy of treatment with radical scavengers for age-related hearing loss. SUBJECTS AND METHODS:Rebamipide (300 mg/day), alpha...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016480802008215
更新日期:2009-01-01 00:00:00
abstract:CONCLUSION:The Finnish Matrix Test is the first sentence test in noise for the Finnish language. It was developed according to the HearCom standards and provides reliable speech intelligibility measurements with highly comparable results with the other international matrix tests. OBJECTIVES:The aim of the study was to...
journal_title:Acta oto-laryngologica
pub_type: 临床试验,杂志文章
doi:10.3109/00016489.2014.898185
更新日期:2014-07-01 00:00:00
abstract:CONCLUSION:We report a distinct pattern of tongue movement. This is interpreted as a compensatory mechanism after hypopharyngo-laryngectomy with reconstruction using a jejunal autograft. Passage through the oesophagus is mainly passive. OBJECTIVE:Swallowing is normally initiated voluntarily, and afterwards presumed to...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016481003664785
更新日期:2010-09-01 00:00:00
abstract::Almost all the pathological and physiological process that effect the nose will change the volume of the airspace within it. This volume has previously been difficult to measure but a new method that calculates this space has been developed. A mechanical model was built to test the physical parameters involved in maki...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489709117791
更新日期:1997-03-01 00:00:00
abstract::A comparison was made between polysomnographic recordings and recordings of airflow pressures in the pharynx and respiratory pressures in the esophagus of 10 adult sleeping subjects with differing degrees of apnea. Pressure measurements were obtained by microsensors mounted on a 7F gauge flexible catheter which sited ...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489509139346
更新日期:1995-05-01 00:00:00
abstract:CONCLUSION:Younger children tend to harbor more resistant strains because they are exposed to these pathogens more often through contacts with siblings or attendance at day-care centers and are frequently treated with antibiotics. The high prevalence of BLNAR strains should be taken into account in the treatment of AOM...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016480410020301
更新日期:2005-02-01 00:00:00
abstract::The ultrastructural features of the interferon-treated adult laryngeal papillomas are described. Compared with untreated papillomas, no differences in ultrastructure were found by transmission electron microscopy. By scanning electron microscopy, significant alterations comprising a smooth and oedematous surface with ...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016488509104793
更新日期:1985-09-01 00:00:00
abstract::During a one-year period, 82 consecutive patients seeking medical attention for facial palsy primarily of unknown etiology were examined for underlying Ixodes ricinus-borne borreliosis. Evidence of the infection was found in 16 (20%) of the patients, most of whom had cerebrospinal fluid findings indicating meningeal i...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016488809119451
更新日期:1988-01-01 00:00:00
abstract:CONCLUSION:Given the phonetic balancing across lists and the validation with spectrally degraded speech, the present Mandarin disyllable recognition test (DRT) materials may be useful for assessing speech performance of Mandarin-speaking cochlear implant (CI) users. If combined with the previously developed sentence ma...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489.2011.653668
更新日期:2012-08-01 00:00:00
abstract::Following responses to constant velocity and sinusoidally oscillating movements of the whole visual environment were examined in normal subjects wearing blinkers to obscure central vision or subjected to a photo flash to induce a central scotoma, in patients with central scotomas of pathological origin and in one pati...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016487909126455
更新日期:1979-05-01 00:00:00
abstract::Acoustic rhinometry (AR) evaluates the geometry of the nasal cavity by measuring the minimum cross-sectional area (MCA) and nasal volume (V) by means of acoustic reflection. Understanding the normal and pathologic conditions of the internal nasal cavity using AR is important in the diagnosis of structural abnormalitie...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016480152602311
更新日期:2001-10-01 00:00:00
abstract::The change in the EP, CM, SP and AP during perilymphatic perfusion of vasopressin (antidiuretic hormone) was examined in the guinea pig. The EP was recorded with a microelectrode through the spiral ligament of the second turn. The CM, SP and AP were measured with the differential electrodes in the basal turn. The perf...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016488609132830
更新日期:1986-03-01 00:00:00
abstract::During the development of the mammalian inner ear, the number of hair cells produced is highly regulated and remains constant throughout life. The mechanism underlying this regulation is beginning to be understood although many aspects still remain obscure. When late embryonic or early postnatal rat organs of Corti we...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/000164801300043325
更新日期:2001-01-01 00:00:00
abstract::The vestibular and optokinetic responses of a group of white cats were evaluated and compared with the responses from a control group of pigmented animals. The results indicate that in all cases the white cats exhibited varying degrees of vestibular and/or optokinetic dysfunction, which in some animals varied from tes...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016487709123944
更新日期:1977-07-01 00:00:00