Abstract:
:The ultrastructural features of the interferon-treated adult laryngeal papillomas are described. Compared with untreated papillomas, no differences in ultrastructure were found by transmission electron microscopy. By scanning electron microscopy, significant alterations comprising a smooth and oedematous surface with a uniform microvilli pattern of the superficial cells were observed after interferon therapy. Our observations suggest an increased cell adhesion and maturation of epithelial cells caused by interferon.
journal_name
Acta Otolaryngoljournal_title
Acta oto-laryngologicaauthors
Bomholt A,Horn Tdoi
10.3109/00016488509104793subject
Has Abstractpub_date
1985-09-01 00:00:00pages
304-8issue
3-4eissn
0001-6489issn
1651-2251journal_volume
100pub_type
杂志文章abstract:CONCLUSION:Although this study did not show higher risk of oropharyngeal malignancy in HIV patients overall, they still had much higher prevalence of NHL as well as HL than HIV negative patients. Presence of cervical lymphadenopathy is unreliable in differentiating malignant oropharyngeal tumours from benign lymphoid h...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489.2016.1170878
更新日期:2016-09-01 00:00:00
abstract:CONCLUSION:Chronic subjective dizziness (CSD) is frequent and affects twice as many women as men. Anxiety is a strong predisposing factor. The pathophysiologic concept of this disorder assumes that balance function and emotion share common neurologic pathways, which might explain that the balance disorder can provoke f...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016480701805455
更新日期:2008-10-01 00:00:00
abstract::Based on the late results of tympanoplasty on 300 ears and of one-stage mastoidectomy and tympanoplasty on 269 discharging ears, the problems involved in staging tympanoplasty are discussed. The results of one-stage operations were found to be satisfactory 2-10 years after operation. The frequency of recurrent cholest...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016487609120906
更新日期:1976-09-01 00:00:00
abstract::Test-retest variability of values for directional asymmetry in primary and secondary horizontal optokinetic after-nystagmus (OKAN I and OKAN II, respectively) was studied in 16 apparently healthy subjects. OKAN was induced by 60 s of whole-field optokinetic stimulation at speeds of 60 degrees/s and 90 degrees/s in eit...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489209100776
更新日期:1992-01-01 00:00:00
abstract::In 12 healthy volunteers, and 5 prelingually and 5 postlingually profoundly deaf subjects, a 500 Hz filtered click stimulus was applied to the mastoid via the bone conductor. In all the healthy volunteers, middle latency response (MLR) was recorded. Among all profoundly deaf subjects, MLR was recorded only in 2 with p...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016488509108929
更新日期:1985-03-01 00:00:00
abstract:CONCLUSIONS:The vestibular function can be assessed by ice-water caloric test, rotational chair test and VEMP recording in severely hearing impaired infants and young children, and 85% of these patients showed abnormal responses in these tests. OBJECTIVES:To evaluate the vestibular function of infants and young childr...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016480601002039
更新日期:2007-07-01 00:00:00
abstract::Taking advantage of a natural experimental situation, we compared, retrospectively, functional results after nasalization and ethmoidectomy for diffuse nasal polyposis. Nasalization was a radical ethmoidectomy systematically removing all the bony lamellae and mucosa within the labyrinth, with large antrostomy, sphenoi...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489709113445
更新日期:1997-07-01 00:00:00
abstract:CONCLUSION:Our results suggest that hepatocyte growth factor (HGF) may play an important role in the progression of hypopharyngeal cancer. OBJECTIVE:HGF, a potent stimulator of hepatocyte growth, stimulates the motility, invasiveness, proliferation and morphogenesis of epithelium and may be involved in physiologic and...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016480510037014
更新日期:2006-01-01 00:00:00
abstract::Transtympanic electrocochleography (TT ECoG) was conducted in 61 patients (61 ears) with the clinical diagnosis of Meniere's disease and 15 patients (21 ears) with cochlear hearing loss of other aetiologies to assess the ability of the method to separate different cochlear disorders. The click-evoked summation potenti...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016489850154838
更新日期:1998-03-01 00:00:00
abstract::Normal subjects were exposed to two kinds of optokinetic stimulation, viz. at speeds of 60 degrees/s and 90 degrees/s preceded by acceleration at 6 degrees/s2 and 4.5 degrees/s2, respectively. In most subjects the speed of the eye in the slow nystagmus phase equalled the speed of the rotating device during the acceler...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016487709123954
更新日期:1977-09-01 00:00:00
abstract::Cisplatin and gentamicin are two ototoxicants that are supposed to be transported by the paracellar route, i.e. via cellular junctions, to the perilymphatic compartment. This study was initiated to test the hypothesis that susceptive variation of individuals to ototoxic drugs may be explained by variability in transpo...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/000164800750061624
更新日期:2000-10-01 00:00:00
abstract::The facial nerve of the albino rat was compressed by inserting a thin nylon thread in the facial canal. After a survival period of 1-60 days, the animal was perfused with Ringer's solution followed by a 2% periodate-lysine-paraformaldehyde fixative. Frozen sections from the brain stem containing the facial motor nucle...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489409126055
更新日期:1994-05-01 00:00:00
abstract:CONCLUSION:Glucocorticoid (GC) administration enhanced apoptotic changes in mature olfactory receptor neurons (ORNs). GC administration may enhance regeneration of olfactory epithelium (OE). OBJECTIVES:The mechanism underlying olfactory epithelial cells turnover involves apoptosis replaced by new ORNs. On regeneration...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016480802530663
更新日期:2009-09-01 00:00:00
abstract::Background: Frequency-specific hearing studies are important for predicting hearing results and the prognosis after stapes surgery, to prepare for the rehabilitation of frequency-specific hearing in patients with otosclerosis.Objectives: To evaluate outcomes of stapes surgery of Chinese otosclerosis patients with diff...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016489.2020.1724331
更新日期:2020-05-01 00:00:00
abstract::Patients with Bell's palsy were investigated with regard to the cellular immune response during the acute and convalescent stages with the purpose of acquiring information concerning the etiology of the condition. In order to ascertain whether there was activation of the immune system, the proportion of activated T ce...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016488809119452
更新日期:1988-01-01 00:00:00
abstract:CONCLUSION:The aetiology of Zenker's diverticulum is likely to be multifactorial. The geographical and racial variation in the prevalence and the rare familial cases suggest that genetic predisposition might have a role in the pathogenesis. The mode of inheritance in the rare possible familial cases seems to be autosom...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016480701813822
更新日期:2008-09-01 00:00:00
abstract:CONCLUSION:Di-K19Hc is a promising new ototopical antibiotic for treatment of middle ear infections associated with antibiotic-resistant bacteria. OBJECTIVES:Di-K19Hc was previously shown to exert profound antimicrobial activity against a variety of antibiotic-resistant bacteria and fungi. In this study, we evaluated ...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016480903536036
更新日期:2010-08-01 00:00:00
abstract::Upper airway symptoms are common, but there is little information available on clinical findings in relation to indoor air pollution. This pilot study was conducted to test whether increased levels of indoor air pollutants in schools may correlate to a swelling of the nasal mucosa. The assumption was made that the deg...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489709113467
更新日期:1997-09-01 00:00:00
abstract::Five temporal bones and three surgical cochlear nerve specimens from patients who previously underwent labyrinthectomy were studied by light and electron microscopy. All cochleas had nearly total loss of sensory cells, extensive or total loss of both cochlear nerve fibers in the osseous spiral lamina, and spiral gangl...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016488109138495
更新日期:1981-03-01 00:00:00
abstract:CONCLUSIONS:This is the first report of mandibular reconstruction using the retroauricular (RA) or the modified face-lift (MFL) approach in head and neck cancer. This approach may have advantages over the conventional approach, especially in its superior aesthetic results. OBJECTIVE:The fibular osseous or osteocutaneo...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489.2014.986757
更新日期:2015-05-01 00:00:00
abstract::The nasal airways of 94 healthy term infants (37-42 weeks gestational age) were examined by continuous wide-band noise acoustic rhinometry under standardized conditions on the second or third day postpartum. Validation of the flexible infant probe on tubular plastic models with dimensions similar to the nasal cavity o...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489709113416
更新日期:1997-05-01 00:00:00
abstract::The diagnosis and management of spontaneous otogenic pneumocephalus with literature review is described. A young sportsman experienced headache and fluctuating mass in his occiput during increased physical activity. A large extradural intracranial pneumocephalus with corresponding emphysema was imaged on a CT scan. Tr...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章,评审
doi:10.3109/00016489.2010.541941
更新日期:2011-06-01 00:00:00
abstract::To elucidate immune mechanisms in otitis media, middle ear infection was induced in 12 rats by intratympanic inoculation of Streptococcus pneumoniae type 3, either the ipsilateral or the contralateral middle ear being re-challenged 4 weeks later. Otomicroscopy inspection confirmed the presence of acute otitis media (A...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489109100760
更新日期:1991-01-01 00:00:00
abstract::Background: It has been reported that head-up sleep (HUS) prevents free-floating otoliths from entering canals and that vertical recognition training (VRT) promotes vestibular compensation.Aims/objectives: We would like to assess HUS and VRT for intractable motion-evoked dizziness, including possible benign paroxysmal...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016489.2020.1727566
更新日期:2020-06-01 00:00:00
abstract:CONCLUSION:The endoscopic approaches developed for the treatment of the chordomas according to the different clival location provide the possibility for more complete tumor resection with maximal preservation of anatomic structures and reduction of the overall incidence of complications. OBJECTIVE:The endoscope has re...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016480801995404
更新日期:2009-01-01 00:00:00
abstract:CONCLUSION:The developed software (HITCal) may be a useful tool in the analysis and measurement of the saccadic video head impulse test (vHIT) responses and with the experience obtained during its use the authors suggest that HITCal is an excellent method for enhanced exploration of vHIT outputs. OBJECTIVE:To develop ...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489.2015.1035401
更新日期:2015-09-01 00:00:00
abstract:CONCLUSIONS:Increased expression of Dicer may be a prognostic biomarker for patients with laryngeal squamous cell carcinoma (LSCC). OBJECTIVES:Recent studies have shown that many microRNAs (miRNAs) play an important role in the development and progression of human cancers. Dicer, one of the most important enzymes of t...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489.2014.920962
更新日期:2014-09-01 00:00:00
abstract::It has already been reported that anaphylatoxin (AT) is closely related to inner ear lesions. In this study the pathology of inner ear damage caused by AT was investigated in Hartley strain and C4 deficient guinea pigs (C4D-GP). Although the biological activity of C3a and C5a is strong, it is of short duration, and th...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016489.1992.11665416
更新日期:1992-01-01 00:00:00
abstract:CONCLUSION:This study suggests that hyperbilirubinemia in the neonatal rat can impair auditory function and induce peripheral nerve pathology by reducing neurofilament-positive cells in spiral ganglion neurons (SGNs). This finding indicates a potential connection between hyperbilirubinemia and auditory impairment. OBJ...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489.2014.938361
更新日期:2014-11-01 00:00:00
abstract::Caloric responses from 50 consecutive patients, referred routinely for investigation of hearing and/or balance problems, were evaluated by computer and manual methods of analysis. Using measures of nystagmic slow-phase velocity, there was found to be a high degree of correlation between the two methods. Of the 50 pati...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016488709128267
更新日期:1987-11-01 00:00:00