Histological study of chronic electrode implantation through the round window of the guinea pig.

Abstract:

:A platinum-iridium electrode with a Teflon cover tube was chronically implanted through the round window into the scala tympani of the guinea pig. Animals were sacrificed at 30 to 40 weeks after electrode implantation, and the cochleae were observed by scanning electron microscopy or with light microscopy. The results revealed that the electrode was firmly enclosed with fibrous tissue on the inside of the round window and with epithelial tissue on the outside. These tissues were considered to act as a barrier to the entry of infection while preventing leakage of the perilymph.

journal_name

Acta Otolaryngol

journal_title

Acta oto-laryngologica

authors

Gyo K

doi

10.3109/00016488809097005

subject

Has Abstract

pub_date

1988-03-01 00:00:00

pages

248-54

issue

3-4

eissn

0001-6489

issn

1651-2251

journal_volume

105

pub_type

杂志文章
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    abstract::Craniotomy with cerebrospinal fluid (CSF) suction was performed on 18 guinea pigs to determine the effects on the inner ear morphology. Six control animals received anaesthesia only and 12 were operated on with a postoperative survival time of 1 or 24 h. The histologic examinations showed no signs of endolymphatic hyd...

    journal_title:Acta oto-laryngologica

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.3109/00016489409126116

    authors: Walsted A,Garbarsch C,Michaels L

    更新日期:1994-11-01 00:00:00

  • The olfactory and respiratory epithelium in rhesus and squirrel monkeys studied with freeze-fracture technique.

    abstract::Olfactory and respiratory epithelia was prepared for thin-section and freeze-fracture replicas, and were investigated using electron microscopy. Three cell types were identified in the olfactory epithelium: olfactory receptor neurons (ORN), sustentacular cells (SC) and basal cells (BC); and respiratory epithelial cell...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.3109/00016488909125526

    authors: Engström B,Ekblom A,Hansson P

    更新日期:1989-09-01 00:00:00

  • Comparison of preoperative and postoperative radiation therapy for patients with carcinoma of the head and neck. Interim report.

    abstract::Three hundred and fifty-four patients with squamous cell carcinoma of the oral cavity, oropharynx, supraglottic larynx, hypopharynx or maxillary sinus have been randomized for preoperative radiation therapy and surgery versus surgery and postoperative radiation therapy plus, in the case of patients with lesions of the...

    journal_title:Acta oto-laryngologica

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.3109/00016488109138548

    authors: Snow JB,Gelber RD,Kramer S,Davis LW,Marcial VA,Lowry LD

    更新日期:1981-05-01 00:00:00

  • Psychosomatic aspects of Menière's disease.

    abstract::The author presents a study of the personality structure, youth development and the role of interhuman conflicts in the work situation and the family, in the causation and course of Menière's disease, the somatopsychic reactions of the patients to the illness, and the principles of a form of psychotherapy which was co...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.3109/00016488309139423

    authors: Groen JJ

    更新日期:1983-05-01 00:00:00

  • Expression of glycoconjugates in normal and Sjögren's syndrome labial glands.

    abstract::Glyconjugate expression in formalin-fixed, paraffin-embedded Sjögren's syndrome labial glands (nine cases) was compared with that in normal glands (12 samples) using a wide panel of lectins. Mucous cells expressed mainly mucous-type glycoproteins including sialyl, fucosyl, galactosyl and galactosaminosyl residues, and...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.3109/00016489709114217

    authors: Sidagis J,Ueno K,Wang ZH,Hanamure Y,Furuta S,Ohyama M

    更新日期:1997-11-01 00:00:00

  • Compensatory mechanisms induced by high oropharyngeal airway resistance in rats.

    abstract::Acid base balance changes were observed during 72 h following bilateral nasal obstruction in rats. Mouth breathing caused acute respiratory acidosis and marked aerophagia, leading to spontaneous death of the experimental animal 80 to 90 h postoperatively. Stenotic oropharyngeal airway, due to palatal-epiglottic approx...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.3109/00016489109137406

    authors: Kalogjera L,Pegan B,Petric V

    更新日期:1991-01-01 00:00:00

  • Clinical relevance of magnetic resonance imaging and computed tomography in Cogan's syndrome.

    abstract::The Pathologic changes in the inner ears of 5 patients with Cogan's syndrome were studied by a combined application of MR imaging and CT scanning. We used T1- and T2-weighted MR imaging sequences and a special three-dimensional MR imaging technique which allows a very detailed imaging of the inner ear structures. By t...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.3109/00016489309135875

    authors: Majoor MH,Albers FW,Casselman JW

    更新日期:1993-09-01 00:00:00

  • Extracellular ATP-induced Ca2+ mobilization of type I spiral ganglion cells from the guinea pig cochlea.

    abstract::Intracellular calcium concentrations ([Ca2+]i) in type I cochlear spiral ganglion cells (SGCs) of the guinea pig were measured by digital imaging microscopy and the Ca(2+)-sensitive dye Fura-2. Extracellular ATP induced elevation of [Ca2+]i in type I SGCs in a concentration-dependent manner. The ATP-induced elevation ...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.3109/00016489709113435

    authors: Cho H,Harada N,Yamashita T

    更新日期:1997-07-01 00:00:00

  • Cell proliferation in the endolymphatic sac in situ after inner ear immunostimulation.

    abstract::Cell proliferation in the endolymphatic sac (ES) after immunostimulation was assessed immunohistochemically. Guinea pigs were employed as experimental animals and keyhole limpet hemocyanin was used as the antigen. After i.p. injection of 5-bromo-2'-deoxyuridine (BrdUrd), the BrdUrd+ cells were counted to assess the nu...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.3109/00016489509139336

    authors: Takahashi M,Tomiyama S

    更新日期:1995-05-01 00:00:00

  • Observations on the structure and the biomechanics of the cricothyroid articulation.

    abstract::We examined quantitatively the ventrodorsal gliding occurring along a sagittal plane in the cricothyroid articulation. For this purpose we used 10 fresh excised human larynges taken at autopsy. Furthermore we examined the morphology, the hydroxyproline content and collagen types of the ligaments and the articular caps...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.3109/00016488709134706

    authors: Vilkman EA,Pitkänen R,Suominen H

    更新日期:1987-01-01 00:00:00

  • Radix Astragali injection enhances recovery from acute acoustic trauma.

    abstract:CONCLUSION:The average recovery of hearing and cessation of tinnitus was significantly better after treatment with Radix Astragali (RA) than after non-treatment with RA. RA can be valuable adjuvant therapy for patients with acute acoustic trauma (AAT). OBJECTIVES:AAT is one of the early indications for the use of RA. ...

    journal_title:Acta oto-laryngologica

    pub_type: 临床试验,杂志文章

    doi:10.3109/00016489.2011.591823

    authors: Xiong M,He Q,Lai H,Huang W,Wang L,Yang C,Wang J

    更新日期:2011-10-01 00:00:00

  • Concentrations of chemical mediators in nasal secretions of patients with hay fever during natural allergen exposure.

    abstract::By using the microsuction technique, quantitative determination of the chemical mediators in nasal secretions was performed in 40 patients with seasonal allergic rhinitis during the pollen season. The aim of this study was to investigate the actual concentrations of these important mediators in nasal secretions during...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.3109/00016489409126103

    authors: Wang D,Clement P,Smitz J,Derde MP

    更新日期:1994-09-01 00:00:00

  • Diclofenac (Voltaren). Pain-relieving effect after tonsillectomy.

    abstract::The efficacy of diclofenac suppositories was estimated in a two-centre, double-blind, placebo-controlled study comprising 97 patients (47 in the diclofenac group and 50 in the placebo group). The series from the two centres and patients in the two treatment groups were comparable. Immediately postoperatively, the pati...

    journal_title:Acta oto-laryngologica

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.3109/00016488409107553

    authors: Dommerby H,Rasmussen OR

    更新日期:1984-07-01 00:00:00

  • Variation in bacterial count in otorrhea from cases of chronic otitis media depending upon the method of antibiotic administration.

    abstract::Patients with chronic otitis media (COM) were divided into two groups, one to be given Cephalexin (CEX) orally and the other to be given CEX ear drops locally. The counts of viable bacteria in otorrheal samples collected before and after CEX administration were determined. The incidence of decrease in the count of bac...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.3109/00016488109133264

    authors: Sugiyama M,Tanabe K,Chang KC,Nakai Y

    更新日期:1981-09-01 00:00:00

  • A comparison of the furosemide and glycerol tests for Meniere's disease. With special reference to the bilateral lesion.

    abstract::The feasibility of furosemide test for the detection of endolymphatic hydrops has previously been discussed (Authors, 1973, 1975). The glycerol test also has been reported as being effective for the same purpose but only in Meniere patients with fluctuating hearing loss (Klockhoff & Lindblom, 1966). In 48 patients wit...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.3109/00016487709128845

    authors: Futaki T,Kitahara M,Morimoto M

    更新日期:1977-03-01 00:00:00

  • Management of the neck in node-positive tonsillar cancer.

    abstract:CONCLUSION:Neck dissection (ND) may not be warranted for those patients with complete response in the neck. Human papillomavirus (HPV)-positive or -negative tumour does not affect this recommendation. OBJECTIVES:Treatment of tonsillar cancer varies considerably worldwide, although non-surgical treatment, e.g. radiothe...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.3109/00016489.2014.920516

    authors: Marklund L,Lundberg B,Hammarstedt-Nordenvall L

    更新日期:2014-10-01 00:00:00

  • Postnatal development of vestibular receptor surfaces in the rat.

    abstract::The development of vestibular receptor surfaces was studied during the postnatal period in the rat on the 1st, 7th, 13th, 32nd and 75th days after birth. Cristae and utricles increase and change their shapes, up to day 13 for the cristae and day 32 for the utricles. Cristae hair bundles are less developed than those o...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.3109/00016488609108602

    authors: Dechesne C,Mbiene JP,Sans A

    更新日期:1986-01-01 00:00:00

  • Double-blind, randomized, multicenter study comparing the effect of betahistine and flunarizine on the dizziness handicap in patients with recurrent vestibular vertigo.

    abstract:OBJECTIVE:The aim of this double-blind, randomized, multicenter study was to compare the efficacy of betahistine dihydrochloride (BH) and flunarizine (FL) using the Dizziness Handicap Inventory (DHI), a validated self-assessment questionnaire that has not previously been used in a clinical trial to evaluate antivertigo...

    journal_title:Acta oto-laryngologica

    pub_type: 临床试验,杂志文章,多中心研究,随机对照试验

    doi:10.1080/00016480310001475

    authors: Albera R,Ciuffolotti R,Di Cicco M,De Benedittis G,Grazioli I,Melzi G,Mira E,Pallestrini E,Passali D,Serra A,Vicini C

    更新日期:2003-06-01 00:00:00

  • Gain and phase characteristics of compensatory eye movements in light and darkness. A study with a broad frequency-band rotatory test.

    abstract::Thirteen normal subjects were investigated with a broad frequency-band (up to 4.5 Hz) rotatory test. The vestibular stimulation consisted of either a pseudo-random or a sinusoidal frequency sweep oscillation. Eye movements were recorded by EOG. Head movements were recorded either by a potentiometer attached to the cha...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.3109/00016488409130983

    authors: Larsby B,Hydén D,Odkvist LM

    更新日期:1984-03-01 00:00:00

  • Social handicap among workers with noise-induced hearing loss.

    abstract::A thorough examination of hearing and hearing loss among workers in the saw- and papermill industries in northern Sweden showed that even a serious hearing loss does not give the expected social handicap. ...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.3109/00016487609119960

    authors: Diamant H

    更新日期:1976-03-01 00:00:00

  • Epstein-Barr virus infection and plasma transforming growth factor-beta1 levels in head and neck cancers.

    abstract:CONCLUSIONS:In addition to the correlation of transforming growth factor (TGF)-beta1 levels to the radiation toxicity, both Epstein-Barr virus (EBV) infection and postoperative status play roles in the change in plasma TGF-beta1 levels in patients with head and neck cancers. OBJECTIVES:To assess the parameters involve...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.1080/00016480701714293

    authors: Chen HW,Yang SF,Chang YC,Wang TY,Chen YJ,Hwang JJ

    更新日期:2008-10-01 00:00:00

  • Effects of Semont maneuver on benign paroxysmal positional vertigo: a meta-analysis.

    abstract:BACKGROUND:Benign paroxysmal positional vertigo (BPPV) is the most common type of peripheral vertigo. This study aimed to evaluate the effects of the Semont maneuver (SM) for BPPV treatment, compared with other methods. METHODS:Studies were selected in relevant databases under pre-defined criteria up to June 2015. The...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章,meta分析

    doi:10.1080/00016489.2016.1212265

    authors: Zhang X,Qian X,Lu L,Chen J,Liu J,Lin C,Gao X

    更新日期:2017-01-01 00:00:00

  • Histopathologic assessment of fungal involvement of the paranasal sinuses in Turkey.

    abstract:OBJECTIVE:To assess paranasal sinus material histopathologically for the presence of fungus. MATERIAL AND METHODS:Paraffin-embedded archival biopsy samples of patients who underwent endonasal sinus surgery between 1992 and 2002 were retrospectively assessed for the presence of fungi. Hematoxylin-eosin-stained sections...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.1080/00016480310001222

    authors: Erkiliç S,Aydin A,Bayazit YA,Güldür E,Deniz H,Bayazit N,Ozer E

    更新日期:2003-04-01 00:00:00

  • The relevance of migraine in patients with Meńière's disease.

    abstract:CONCLUSION:Coexistent migraine affects relevant clinical features of patients with Ménière's disease (MD). OBJECTIVE:Epidemiological studies have shown an association between migraine and MD. We sought to determine whether the coexistence of migraine affects any clinical features in patients with MD. PATIENTS AND MET...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.1080/00016480701242469

    authors: Cha YH,Brodsky J,Ishiyama G,Sabatti C,Baloh RW

    更新日期:2007-12-01 00:00:00

  • Effects of perilymphatically perfused gentamicin on microphonic potential, lipid labeling and morphology of cochlear tissues.

    abstract::The perilymphatic space of the guinea pig was perfused in situ with artificial perilymph containing [32P] orthophosphate and 3H-glycerol while cochlear microphonic potentials (CM) were monitored. The perfusion of 10 mM gentamicin suppressed CM by 62% within 30 min. 32P-incorporation into phosphatidylinositol bisphosph...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.3109/00016488309132872

    authors: Tachibana M,Anniko M,Schacht J

    更新日期:1983-07-01 00:00:00

  • A novel method for determining the relation between nasal polyposis and oxidative stress: the thiol/disulphide homeostasis.

    abstract:CONCLUSION:It is thought that oxidative stress may be the major cause of the increase in the oxide thiol form in the study group. The relationship between oxidative stress status and dynamic thiol/disulphide in nasal polyposis now needs to be investigated. OBJECTIVES:The purpose of this study was to evaluate the relat...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.1080/00016489.2016.1186833

    authors: Şimşek E,Erel O,Bicer CK,Çarlıoğlu A

    更新日期:2016-11-01 00:00:00

  • Is horizontal semicircular canal ocular reflex influenced by otolith organs input?

    abstract:CONCLUSION:Otolith organs input influences the axis of horizontal semicircular canal ocular reflex; therefore, the plane of compensatory eye movements induced by the horizontal canal stimulation is not always parallel to the canal. OBJECTIVE:To clarify whether horizontal canal ocular reflex is influenced by otolith or...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.3109/00016489.2012.656286

    authors: Ichijo H

    更新日期:2012-07-01 00:00:00

  • Penetration of enoxacin into middle ear effusion.

    abstract::An oral dose of 400 mg enoxacin was given to each of 19 patients with long-standing secretory otitis media (SOM). A total of 27 samples of middle ear effusion (MEE) and blood were collected at different intervals during a 6-h period after administration of the drug. The concentration of enoxacin in MEE and serum was d...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.3109/00016489009125166

    authors: Sundberg L,Edén T

    更新日期:1990-05-01 00:00:00

  • Polyp formation by experimental tubal occlusion in the rat.

    abstract::The purpose of this study was to show the early stages of polyp formation, as part of our studies on the pathogenesis of nasal polyps. Two and 4 weeks after experimental tubal occlusion in 18 Wistar rats, 13 showed signs of bacterial infection, respective acute otitis media. In the majority of these rats polypouslike ...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.3109/00016489109138432

    authors: Larsen PL,Tos M

    更新日期:1991-01-01 00:00:00

  • PET-methionine of skull base neuromas and meningiomas.

    abstract::Eighteen patients with intracranial skull base tumours diagnosed at CT or MR as neuromas or meningiomas were studied with positron emission tomography (PET) using L-(methyl-11C) methionine. Compared with normal cerebellar tissue, the uptake of methionine in the tumours increased more rapidly and reached a higher level...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.3109/00016489709113425

    authors: Nyberg G,Bergström M,Enblad P,Lilja A,Muhr C,Långström B

    更新日期:1997-07-01 00:00:00