Abstract:
:The Pathologic changes in the inner ears of 5 patients with Cogan's syndrome were studied by a combined application of MR imaging and CT scanning. We used T1- and T2-weighted MR imaging sequences and a special three-dimensional MR imaging technique which allows a very detailed imaging of the inner ear structures. By the use of a CT scan simultaneously, calcified and noncalcified obliterations could be differentiated. The aim of the study was to visualize membranous labyrinth pathology in Cogan's syndrome and correlate them with the clinical findings. In one patient who recovered completely without hearing loss, the MR and CT investigations revealed no pathology. In the remaining 4 cases, narrowing or obliteration of parts of the vestibular labyrinth was seen. In 3 patients, we found aberrations in the cochlea consistent with the audiological data. The gadolinium-enhanced T1-images showed enhancement of the cochlea and vestibular labyrinth in one case, probably indicating an active process with interruption of the "blood-labyrinth barrier". The results are consistent with the hypothesis that the inner ear pathology in Cogan's syndrome is probably caused by obstructive vasculitis.
journal_name
Acta Otolaryngoljournal_title
Acta oto-laryngologicaauthors
Majoor MH,Albers FW,Casselman JWdoi
10.3109/00016489309135875subject
Has Abstractpub_date
1993-09-01 00:00:00pages
625-31issue
5eissn
0001-6489issn
1651-2251journal_volume
113pub_type
杂志文章abstract:CONCLUSIONS:Codeine shows a similar association with profound deafness to other opiates. Good cochlear implant outcomes suggest a sensory disorder. Although macrocytosis could be due to confounding factors, the lack of other consistent findings may signify a vascular pathology. OBJECTIVES:To describe a series of patie...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016480802579082
更新日期:2009-10-01 00:00:00
abstract:CONCLUSION:These findings indicate a strong protective effect of ALCAR and NAC on impulse noise-induced cochlear damage, and suggest the feasibility of using clinically available antioxidant compounds to protect the ear from acute acoustic injury. OBJECTIVE:Reactive oxygen species have been shown to play a significant...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016480410023038
更新日期:2005-03-01 00:00:00
abstract::By means of cleaving the soft palate and blocking the Eustachian tube, two otomicroscopically well defined types of otitis media, serous and purulent, were created in an animal model (rat). The microbiological pattern of these conditions were characterized at 1, 2, 3, 4 and 6 weeks after the onset. Samples were collec...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489009122521
更新日期:1990-07-01 00:00:00
abstract::This study aimed to investigate whether unilateral vestibular neuritis (VN) causes the same deficits of ocular counter-roll during static head roll (OCR(S)) and dynamic vestibulo-ocular reflex gains during head impulses (VOR(HI)) as unilateral vestibular deafferentation (VD). Ten patients with acute and 14 patients wi...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016489950180379
更新日期:1999-01-01 00:00:00
abstract::Nerves displaying vasoactive intestinal peptide (VIP) immunoreactivity were detected in the upper respiratory tract of guinea pigs, rabbits and cats. VIP nerves were numerous in the cat, less numerous in the rabbit and rare in the guinea pig. In the nasal mucosa, fine varicose VIP nerves were found to surround nasal g...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016487809107524
更新日期:1978-11-01 00:00:00
abstract:CONCLUSION:The average recovery of hearing and cessation of tinnitus was significantly better after treatment with Radix Astragali (RA) than after non-treatment with RA. RA can be valuable adjuvant therapy for patients with acute acoustic trauma (AAT). OBJECTIVES:AAT is one of the early indications for the use of RA. ...
journal_title:Acta oto-laryngologica
pub_type: 临床试验,杂志文章
doi:10.3109/00016489.2011.591823
更新日期:2011-10-01 00:00:00
abstract:CONCLUSION:Because nystagmus induced by ampullopetal inhibition of the posterior semicircular canal (PSCC) rotates around the axis perpendicular to the plane of the anterior semicircular canal (ASCC) of the other side, when free-floating debris is initially located at the distal portion of the PSCC, a patient showing p...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489.2012.763180
更新日期:2013-06-01 00:00:00
abstract::The first systematically performed study concerning the size variation of the mastoid air cell system was measured on the X-ray film in a lateral projection, as exposed on the skull table. A new type of equipment (Orbix) with an isocentric motion of the roentgen tube and the film cassette and a different magnification...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016488309130921
更新日期:1983-01-01 00:00:00
abstract::In a previous investigation into noise-induced hearing loss by comparing 2-month-old albino with pigmented guinea pigs, albinos displayed significantly greater shifts in cochlear microphonic (CM) threshold and less recovery than the pigmented animals 7 days after noise exposure. The present study compared the response...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016488809107372
更新日期:1988-07-01 00:00:00
abstract::The penetration of oral erythromycin stearate (Abboticin), administered in a dosage of 500 mg three times a day, into the maxillary sinus mucosa and secretion was studied in 15 patients (22 sinuses) operated on for chronic maxillary sinusitis. The average concentration in serum was 2.3 microgram/ml, 1.2 microgram/ml i...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016487709123970
更新日期:1977-09-01 00:00:00
abstract::Background: The development of hearing and plasticity of brain after cochlear implantation (CI) for prelingually deaf children with white matter changes (group A) is unclear.Objective: To investigate the development of hearing for children in group A during 1 year after CI activation, compared with non-complicated pee...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016489.2020.1720285
更新日期:2020-05-01 00:00:00
abstract:CONCLUSION:Delayed facial palsy after tympanoplasty had no predisposition for gender or side. It seemed that prednisolone alone without antiviral drugs was enough for the treatment of delayed facial palsy after tympanoplasty. OBJECTIVE:To analyze the clinical characteristics and prognosis of delayed facial palsy after...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489.2014.971464
更新日期:2015-02-01 00:00:00
abstract::Undifferentiated giant and spindle cell carcinoma is an unusual and high-grade malignant type of cancer of the thyroid. The results of surgical and/or radiotherapeutic treatment have been discouraging. Only a few patients respond to therapy, usually for a short time. Recently, a few reports have been published on the ...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016487709128859
更新日期:1977-03-01 00:00:00
abstract::The production of middle ear effusion by mechanical stimulation was studied in sympathectomized and vagotomized animals. Mechanical stimulation was obtained by a 14 degree C airstream in the external auditory canal. In sympathectomized animals this procedure caused effusion production and vasoconstriction of pars flac...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016488809107365
更新日期:1988-07-01 00:00:00
abstract::The ultrastructure of the geniculate ganglion was studied in the guinea pig and monkey. Two cytologically distinct colonies of ganglion cells were seen and identified as light and dark cells. All neurons were unmyelinated and most were unipolar, although a few bipolar cells were seen. The axons, upon leaving the cell ...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016488209130869
更新日期:1982-01-01 00:00:00
abstract:OBJECTIVES:To evaluate the long-term (24 months) clinical performance (vocal fold function) and safety of hylan B gel as compared with bovine cross-linked collagen in the treatment of patients with glottal insufficiency. MATERIAL AND METHODS:In a prospective trial, 70 patients with glottal insufficiency due to unilate...
journal_title:Acta oto-laryngologica
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1080/00016480410017701
更新日期:2004-12-01 00:00:00
abstract::The gram negative bacteria, nontypable Haemophilus influenzae (NTHi) was used to induce otitis media in a total of 18 chinchillas. Three days post-inoculation, three cohorts of 6 chinchillas each were treated daily for four days with either ceftriaxone, chloramphenicol, or diluent without antibiotics. Middle ear fluid...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489709118000
更新日期:1997-01-01 00:00:00
abstract::Glyconjugate expression in formalin-fixed, paraffin-embedded Sjögren's syndrome labial glands (nine cases) was compared with that in normal glands (12 samples) using a wide panel of lectins. Mucous cells expressed mainly mucous-type glycoproteins including sialyl, fucosyl, galactosyl and galactosaminosyl residues, and...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489709114217
更新日期:1997-11-01 00:00:00
abstract:CONCLUSION:The increased AQP5 expression associated with ageing in glands, which mainly secreted a serous solution, suggests a compensation for the decreased amount of saliva secretion associated with age progression. OBJECTIVE:To investigate the change in aquaporin-1 (AQP1) and aquaporin-5 (AQP5) expression in the sa...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489.2016.1165353
更新日期:2016-09-01 00:00:00
abstract:OBJECTIVE:To report on the long-term results, focusing on prosthesis lifetime, achieved with the VoiceMaster prosthesis in an outpatient population. MATERIAL AND METHODS:The VoiceMaster prosthesis was used over a 40-month period. Average prosthesis lifetimes were calculated both individually and for the group as a who...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016480310001330
更新日期:2003-06-01 00:00:00
abstract::The postnatal development of lower stations in the auditory pathway was studied in the guinea pig by recording auditory brainstem potentials. At birth, the brainstem responses of young guinea pigs already have thresholds corresponding to those of adult animals. However, the latencies of the individual potentials are s...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016488409130965
更新日期:1984-01-01 00:00:00
abstract::In the last few years the use of ABR in the dysmetabolic encephalopathies has aroused considerable interest. Even though brainstem involvement in these syndromes is not yet entirely understood, ABR techniques have provided new and important insights. We studied 60 insulin-dependent diabetic subjects, 29 females and 31...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:
更新日期:1987-05-01 00:00:00
abstract:BACKGROUND:Combination therapy consisting of a platinum agent, 5-fluorouracil and cetuximab (EXTREME regimen) is recommended for recurrent or metastatic squamous cell carcinoma of the head and neck (R/M-SCCHN). However, it is advisable to use platinum-free regimens as first-line therapy in patients resistant to platinu...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章,多中心研究
doi:10.1080/00016489.2018.1551623
更新日期:2019-02-01 00:00:00
abstract:CONCLUSION:Gene transcription and protein expression of α-ENaC showed a divergent expression in association with the development of OME induced by barotrauma. OBJECTIVES:ENaC was identified to mediate the fluid absorption through epithelia of the middle ear. This study was designed to investigate the involvement of EN...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489.2015.1017888
更新日期:2015-07-01 00:00:00
abstract::Patients with hemifacial spasm and trigeminal neuralgia later treated with microvascular decompression and surgical interposition for their vascular loop disturbance were investigated preoperatively with electronystagmography, saccade test and audiometry. Some of them underwent an extended investigation including comp...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016488809119522
更新日期:1988-05-01 00:00:00
abstract:CONCLUSION:Nasal obstruction, rhinorrhea, and the amount of rhinorrhea that confidently reflect the parasympathetic stimulation can be used to more precisely predict nonspecific nasal hyper-reactivity (NHR). OBJECTIVE:We aimed to identify factors that confidently reflected the presence and the degree of NHR, measured ...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489.2012.681798
更新日期:2012-10-01 00:00:00
abstract:PURPOSE:To analyze the outcomes following re-irradiation for local recurrence of rare head and neck tumors. MATERIAL AND METHODS:We retrospectively analyzed 11 patients who had received intensity-modulated radiation therapy (IMRT) for recurrent tumors in the head and neck except for laryngopharynx. RESULTS:Primary tu...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016489.2018.1438662
更新日期:2018-08-01 00:00:00
abstract:CONCLUSIONS:The procedure cleared the lesion completely and preserved the physiological function of the external auditory canal. OBJECTIVE:To develop a novel surgical procedure to treat chronic suppurative otitis media (CSOM). To explore the merit of using pedicled temporalis myofascia (PTM) and reconstruction of the ...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489.2013.767987
更新日期:2013-07-01 00:00:00
abstract:CONCLUSION:Partial deafness cochlear implantation (PDCI) is a feasible means of treating individuals who have good low frequency hearing, but a severe to profound hearing loss in the mid to high frequencies. The individuals have benefit in noise and show significant benefit in a number of difficult listening conditions...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016480600606632
更新日期:2006-09-01 00:00:00
abstract::There is no single technique for reconstruction of the canal wall following radical mastoidectomy. Autograft tissues may be unsuitable because of resorption and limited availability. An ideal foreign implant material should be bone-like in quality, non-ototoxic, readily available and malleable. Plaster of Paris, a deg...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016488609108631
更新日期:1986-05-01 00:00:00