Abstract:
PURPOSE:To analyze the outcomes following re-irradiation for local recurrence of rare head and neck tumors. MATERIAL AND METHODS:We retrospectively analyzed 11 patients who had received intensity-modulated radiation therapy (IMRT) for recurrent tumors in the head and neck except for laryngopharynx. RESULTS:Primary tumor sites included the maxillary sinus, nasal cavity, and external ear canal in six, three, and two patients, respectively. The median follow-up times were 13 (range, 3-54) months. The median survival time was 17 months with 1- and 2-year survival rates of 63.64 and 39.77%, respectively. Among 11 patients, five experienced local failure in the follow-up period. The 1- and 2-year local control rates were 58 and 47%, respectively. Patients who had received a radiation dose of ≥3 Gy per fraction showed significantly better local control than those receiving less (p = .0419). One patient experienced Grade 3 facial pain as acute toxicity. Late toxicities included radiographic findings of partial central nervous system necrosis in three patients and Grade 3 osteonecrosis and Grade 3 facial nerve disorder in one patient. CONCLUSIONS:Re-irradiation of rare head and neck tumors using IMRT for loco-regional recurrence may be an acceptable treatment option.
journal_name
Acta Otolaryngoljournal_title
Acta oto-laryngologicaauthors
Doi H,Uemoto K,Masai N,Tatsumi D,Shiomi H,Oh RJdoi
10.1080/00016489.2018.1438662subject
Has Abstractpub_date
2018-08-01 00:00:00pages
750-758issue
8eissn
0001-6489issn
1651-2251journal_volume
138pub_type
杂志文章abstract::The vestibular and optokinetic responses of a group of white cats were evaluated and compared with the responses from a control group of pigmented animals. The results indicate that in all cases the white cats exhibited varying degrees of vestibular and/or optokinetic dysfunction, which in some animals varied from tes...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016487709123944
更新日期:1977-07-01 00:00:00
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journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016489.2019.1666213
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journal_title:Acta oto-laryngologica
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doi:10.3109/00016489.2014.882017
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abstract::We report a case of electromagnetic interference between a bone-anchored hearing aid (BAHA) and a cellular phone. A 54-year-old women was successfully treated for severe mixed conductive and sensorineural hearing loss with a BAHA. Five years after implantation, the patient experienced a sudden feeling of dizziness, ac...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/000164800750061723
更新日期:2000-10-01 00:00:00
abstract::We studied three-dimensional arrangement of collagen fibers and elastic fibers in the human vocal fold by scanning electron microscopy after digesting cellular elements and collagen fibers with formic acid treatment and cellular elements and elastic fibers with 10% sodium hydroxide. The superficial layer consisted of ...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489609137924
更新日期:1996-09-01 00:00:00
abstract:CONCLUSION:Selected patients with Meniere's disease (MD) show an improvement of disability from vertigo after transtympanic ventilation tube insertion, although an effect on vestibular function is not seen if ipsilateral middle ear pressure lower than -50 daPa is used as a selection criterion. OBJECTIVES:Transtympanic...
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pub_type: 杂志文章
doi:10.3109/00016480902791678
更新日期:2009-12-01 00:00:00
abstract::Fibroblasts in two portions of the vocal fold mucosa, the macula flava (MF) and Reinke's space (RS), were investigated by means of transmission electron microscopy. Five adult and five newborn larynges from autopsy cases were subjected to study. Both in adults and newborns, fibroblasts in the MF tended to be stellate ...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016489950181800
更新日期:1999-03-01 00:00:00
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journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489409126013
更新日期:1994-01-01 00:00:00
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journal_title:Acta oto-laryngologica
pub_type: 杂志文章
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journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016489.2017.1296585
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abstract:OBJECTIVES:In this paper we test the concept of combining electrical stimulation for high-frequency sound with acoustic hearing for low-frequency information in the same ear. In addition, we test whether residual hearing can be preserved when an electrode is placed up to 10 mm into the inner ear, and whether the site o...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016480410016423
更新日期:2004-05-01 00:00:00
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journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016480510043468
更新日期:2006-01-01 00:00:00
abstract::The practicability of recording auditory nerve and brainstem responses during early childhood is demonstrated. This paper reports our experience with two different electrode locations: ear-canal/ear-lobe and ear-lobe/vertex. The test is performed with a light portable stimulus-generating and response-recording system ...
journal_title:Acta oto-laryngologica
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更新日期:1979-03-01 00:00:00
abstract::In consecutive series of 326 laryngeal cancer patients, of 29 (9%) with stage T3N0 glottic carcinomas, 23 achieved complete local remission after curative radiotherapy and form the basis of the present investigation. Flow cytometry determinations of DNA-ploidy status and the S-phase fraction, and a "histopathological ...
journal_title:Acta oto-laryngologica
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doi:10.3109/00016489309135796
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journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489009107432
更新日期:1990-03-01 00:00:00
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doi:10.1080/00016489.2017.1341641
更新日期:2017-11-01 00:00:00
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journal_title:Acta oto-laryngologica
pub_type: 临床试验,杂志文章
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更新日期:2014-11-01 00:00:00
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doi:10.1080/00016480310002168
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pub_type: 杂志文章
doi:10.3109/00016489.2012.720029
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pub_type: 杂志文章
doi:10.1080/00016480500534439
更新日期:2006-09-01 00:00:00
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pub_type: 杂志文章
doi:10.1080/00016480510037014
更新日期:2006-01-01 00:00:00
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journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489.2010.536991
更新日期:2011-05-01 00:00:00
abstract::Primary non-Hodgkin's lymphoma of the nasal cavity is a disease more likely to affect men than women; it is characterized by a T cell immunophenotype and is often associated with involvement of the paranasal structures and with high recurrence rates. Many authors report that its extremely poor prognosis depends on tum...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/000164800750046081
更新日期:2000-06-01 00:00:00
abstract::In a previous paper we demonstrated physiologically a sensitive period for acoustic trauma in the rat pup cochlea, with a maximum at 22 days of age. Seven or 60 days after noise exposure these 22-day exposed rats were used for light and electron microscopy. At 7 days, surface preparation revealed restricted damage to ...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016488009127143
更新日期:1980-03-01 00:00:00
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journal_title:Acta oto-laryngologica
pub_type: 杂志文章,随机对照试验
doi:10.3109/00016489.2013.824113
更新日期:2013-12-01 00:00:00
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journal_title:Acta oto-laryngologica
pub_type: 临床试验,杂志文章,多中心研究
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更新日期:2010-09-01 00:00:00
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journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016488909127518
更新日期:1989-05-01 00:00:00
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journal_title:Acta oto-laryngologica
pub_type: 历史文章,杂志文章
doi:10.1080/00016480510043431
更新日期:2005-11-01 00:00:00
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journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016480410017503
更新日期:2004-10-01 00:00:00
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journal_title:Acta oto-laryngologica
pub_type: 杂志文章,随机对照试验
doi:10.3109/00016489.2010.524938
更新日期:2011-03-01 00:00:00