Fibroblasts in human vocal fold mucosa.

Abstract:

:Fibroblasts in two portions of the vocal fold mucosa, the macula flava (MF) and Reinke's space (RS), were investigated by means of transmission electron microscopy. Five adult and five newborn larynges from autopsy cases were subjected to study. Both in adults and newborns, fibroblasts in the MF tended to be stellate in shape, to have a small nucleus/cytoplasm (N/C) ratio, and to have a well developed rough endoplasmic reticulum (rER) and Golgi apparatus (GA). They were active in producing collagenous and elastic fibres. Most fibroblasts in RS were oval in newborns and spindle-shaped in adults. They had a large N/C ratio and less developed rER and GA, indicating that they were inactive in producing fibres. We postulate that many fibroblasts in the newborn and infant MF contribute to the development of the vocal ligament, many of those in the adult MF participate in the metabolism of the vocal ligament, and many of those in RS of both age groups are activated when the vocal fold tissue is injured.

journal_name

Acta Otolaryngol

journal_title

Acta oto-laryngologica

authors

Hirano M,Sato K,Nakashima T

doi

10.1080/00016489950181800

subject

Has Abstract

pub_date

1999-03-01 00:00:00

pages

271-6

issue

2

eissn

0001-6489

issn

1651-2251

journal_volume

119

pub_type

杂志文章
  • Auditory nerve and brainstem responses in the newborn and in preschool children.

    abstract::The practicability of recording auditory nerve and brainstem responses during early childhood is demonstrated. This paper reports our experience with two different electrode locations: ear-canal/ear-lobe and ear-lobe/vertex. The test is performed with a light portable stimulus-generating and response-recording system ...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.3109/00016487909126421

    authors: Montandon PB,Cao MH,Engel RT,Grajew T

    更新日期:1979-03-01 00:00:00

  • Positional nystagmus of central type and its neural mechanism.

    abstract::Observations of Hallpike (1967) suggested that the neural mechanism responsible for positional nystagmus of central type, the direction-changing type of Nylén, was dependent upon derangement of compensatory eye reflexes subserved by neck proprioceptors and/or otolith organs in the presence of damage to the medial vest...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.3109/00016488309139447

    authors: Dix MR

    更新日期:1983-05-01 00:00:00

  • Differences in innervation and secretory behaviour of two nasal glandular parts in the rat.

    abstract::The submucosal glands in the rat nose are characterized by the presence of both neutral and acid glycoproteins, which are important constituents of nasal and tracheobronchial secretions. This study is an attempt to gain a better insight into the secretion of these two types of glycoproteins and its neural regulation. ...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.3109/00016488709128287

    authors: Klaassen AB,Dooper MW,Rodrigues de Miranda JF,Krabbendam H

    更新日期:1987-11-01 00:00:00

  • Laser irradiation of the semicircular canal: occlusion of the canal or duct.

    abstract::The aim of this study was to evaluate the effects of argon laser irradiation of the semicircular canals using computed tomography (CT) images and to examine the basis for laser treatment for benign paroxysmal positional vertigo (BPPV). CT images of the posterior canal were evaluated postoperatively in a patient with i...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.3109/00016489.2011.622292

    authors: Nomura Y,Kobayashi H

    更新日期:2012-01-01 00:00:00

  • Differences in taste detection thresholds between normal-weight and obese young adults.

    abstract:CONCLUSION:Compared with normal-weight individuals, obese young adults exhibited a significantly higher taste threshold for salty taste. Smoking also affected taste functions in this population. OBJECTIVE:The aim of this study was to investigate the differences in taste detection thresholds between normal-weight and o...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.3109/00016489.2014.975370

    authors: Park DC,Yeo JH,Ryu IY,Kim SH,Jung J,Yeo SG

    更新日期:2015-05-01 00:00:00

  • Changes in the characteristics of definite Meniere's disease over time in Japan: a long-term survey by the Peripheral Vestibular Disorder Research Committee of Japan, formerly the Meniere's Disease Research Committee of Japan.

    abstract:CONCLUSION:The incidence of new cases of Meniere's disease (MD) in elderly patients aged 60 years or more was found to have increased over time after correction for age distribution in the overall population. Job- and care-related fatigue may be involved in the recent increase in elderly-onset cases because physical an...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章,多中心研究

    doi:10.1080/00016480802112587

    authors: Shojaku H,Watanabe Y,Yagi T,Takahashi M,Takeda T,Ikezono T,Ito J,Kubo T,Suzuki M,Takumida M,Takeda N,Furuya N,Yamashita H,Peripheral Vestibular Disorder Research Committee of Japan.

    更新日期:2009-02-01 00:00:00

  • The avian stapedius muscle. Influence on auditory sensitivity and sound transmission.

    abstract::The influence of the solitary avian middle ear muscle, the m. stapedius, on auditory sensitivity and sound transmission was investigated in the domestic chicken, Gallus gallus. Electrophysiological recordings of inner ear microphonic potentials (MP) were made in order to determine the effects of calibrated, mechanical...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:

    authors: Counter SA,Borg E

    更新日期:1982-09-01 00:00:00

  • Unexpected findings and surgical complications in 505 consecutive cochlear implantations: a proposal for reporting consensus.

    abstract:CONCLUSION:Cochlear implantation is a safe procedure in experienced hands, as the rate of severe complications is below 2%. Complications differ between children and adults, and transient disequilibrium/vertigo is the most common complication, followed by wound infection, haematoma/oedema and transient chorda tympani s...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.3109/00016480903358261

    authors: Hansen S,Anthonsen K,Stangerup SE,Jensen JH,Thomsen J,Cayé-Thomasen P

    更新日期:2010-05-01 00:00:00

  • Transdermally administered scopolamine vs. dimenhydrinate. II. Effect on different types of nystagmus.

    abstract::The effects of transdermally administered scopolamine (TTS-scopolamine) (release rate 5 micrograms/h, one and two patches) and dimenhydrinate (100 mg) on caloric, angular acceleration induced and optokinetic nystagmus were examined in 16 volunteers in a randomized double-blind study. All drugs induced a statistically ...

    journal_title:Acta oto-laryngologica

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.3109/00016488509182266

    authors: Pyykkö I,Schalén L,Matsuoka I

    更新日期:1985-05-01 00:00:00

  • A simple objective evaluation and grading for facial paralysis outcomes.

    abstract:CONCLUSION:A simple measuring box to determine lip-shift angle and eye-width narrowing offered simultaneous and objective data on outcome dysfunction. The method is as easy as visual approaches. The method is objective and as easy as visual access. It is practical for routine clinical use in any clinic. OBJECTIVES:The...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.3109/00016489.2011.626793

    authors: Saito H

    更新日期:2012-01-01 00:00:00

  • Morphology of tracheal scar after resection with CO2-laser and high-frequency cutting loop. A study in normal pigs.

    abstract::In 6 pigs a bronchoscopical resection of the tracheal mucosa was performed using CO2-laser on one side, and an electric high-frequency cutting loop (ECL) on the other. The pigs were sacrificed 3 months later. On macroscopic examination the tracheal mucosa appeared almost normal on the laser-resected side, while severe...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.3109/00016488909127514

    authors: Vorre P,Illum P,Oster S,Reske-Nielsen E,Larsen KB

    更新日期:1989-03-01 00:00:00

  • The olfactory and respiratory epithelium in rhesus and squirrel monkeys studied with freeze-fracture technique.

    abstract::Olfactory and respiratory epithelia was prepared for thin-section and freeze-fracture replicas, and were investigated using electron microscopy. Three cell types were identified in the olfactory epithelium: olfactory receptor neurons (ORN), sustentacular cells (SC) and basal cells (BC); and respiratory epithelial cell...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.3109/00016488909125526

    authors: Engström B,Ekblom A,Hansson P

    更新日期:1989-09-01 00:00:00

  • The relaxation time of the stapedius reflex in dystrophia myotonica (Steinert).

    abstract::Eight patients with dystrophia myotonica (Steinert) were studied. They all had myotonia and pathological EMG and in some cases other signs of the disease. The 50% relaxation times of the stapedius reflex were significantly prolonged compared with a control group of 40 healthy, young subjects with normal hearing and no...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.3109/00016488209128937

    authors: Zakrisson JE,Blom S

    更新日期:1982-11-01 00:00:00

  • Damaged utricular function clarified by oVEMP in patients with benign paroxysmal positional vertigo.

    abstract:CONCLUSION:Utricular dysfunction in patients with posterior canal benign paroxysmal positional vertigo (pBPPV) was supported by findings for ocular vestibular evoked myogenic potential (oVEMP). OBJECTIVE:To evaluate the utricular and saccular function in patients with pBPPV. METHODS:This study focused on 12 patients ...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.3109/00016489.2012.720030

    authors: Nakahara H,Yoshimura E,Tsuda Y,Murofushi T

    更新日期:2013-02-01 00:00:00

  • Evidence of direct communication of bone marrow cells with the endolymphatic sac in experimental autoimmune labyrinthitis.

    abstract::In experimental autoimmune labyrinthitis, we found that the guinea pigs sensitized with bovine inner ear antigen (IEAg) developed cellular infiltration within the endolymphatic sac (E. sac). In this study, we investigated the distribution of immune mediated cells within bony vascular channels. The channels, which are ...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.3109/00016489309135786

    authors: Yamanobe S,Harris JP,Keithley EM

    更新日期:1993-03-01 00:00:00

  • Immediate postoperative nystagmus and vestibular symptoms after stapes surgery.

    abstract:CONCLUSION:Vestibular disturbance is frequent, but mild even immediately after stapes surgery. Vestibular symptoms improved or disappeared quickly, and they did not correlate with nystagmus. Outpatient stapes surgery performed under local anaesthesia is a feasible approach. OBJECTIVE:Vestibular symptoms are common and...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.3109/00016489.2013.782106

    authors: Hirvonen TP,Aalto H

    更新日期:2013-08-01 00:00:00

  • T3N0 glottic carcinoma: DNA S-phase as a predictor of the outcome after radiotherapy.

    abstract::In consecutive series of 326 laryngeal cancer patients, of 29 (9%) with stage T3N0 glottic carcinomas, 23 achieved complete local remission after curative radiotherapy and form the basis of the present investigation. Flow cytometry determinations of DNA-ploidy status and the S-phase fraction, and a "histopathological ...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.3109/00016489309135796

    authors: Tennvall J,Wennerberg J,Willén R,Ask A,Baldetorp B,Fernö M

    更新日期:1993-03-01 00:00:00

  • Correlation between severity of sleep apnea and upper airway morphology: Cephalometry and MD-CT study during awake and sleep states.

    abstract:CONCLUSION:The data show that the evaluation of obstruction site in patients with obstructive sleep apnea (OSA) should be performed in the sleep state rather than in wakefulness. OBJECTIVE:The aim of this study was to identify correlation between severity of OSA as measured by the apnea-hypopnea index (AHI) and upper ...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.3109/00016489.2010.514007

    authors: Heo JY,Kim JS

    更新日期:2011-01-01 00:00:00

  • The prevalence of hypothyroidism after treatment for laryngeal and hypopharyngeal carcinomas: are autoantibodies of influence?

    abstract:CONCLUSIONS:The incidence rate of hypothyroidism after treatment for laryngeal and hypopharyngeal cancer is high, especially after combination treatment. An association between hypothyroidism and autoantibodies was found. OBJECTIVES:The incidences of hypothyroidism and autoantibodies were assessed retrospectively in 1...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.1080/00016480600818096

    authors: Lo Galbo AM,de Bree R,Kuik DJ,Lips PT,Mary B,Von Blomberg E,Langendijk JA,Leemans CR

    更新日期:2007-03-01 00:00:00

  • Reconstruction of the jugular vein with autotransplantation in an experimental model.

    abstract::In experiments on 11 dogs, the authors attempted to develop a method for avoiding serious complications following simultaneous bilateral radical neck dissection. Both internal jugular veins were resected; one vein was reconstructed with the autologous v. femoralis. Blood flow in the reconstructed vein was normal in th...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.3109/00016488409132914

    authors: Oresković M,Cerenko D,Sanković F,Maticić Z

    更新日期:1984-05-01 00:00:00

  • Ultrastructural changes of the basement membrane zone in benign lesions of the vocal folds.

    abstract::The basement membrane zone (BMZ) of the epithelium of the vocal folds was investigated electron microscopically in 10 patients suffering from various benign lesions and in 3 controls. Various defects were observed: a thickening by deposition of electron dense material, a loss of normal architecture, and a near absence...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.3109/00016489309135774

    authors: Dikkers FG,Hulstaert CE,Oosterbaan JA,Cervera-Paz FJ

    更新日期:1993-01-01 00:00:00

  • Diazepam reduces excitability of amygdala and further influences auditory cortex following sodium salicylate treatment in rats.

    abstract:CONCLUSION:Diazepam can reduce the excitability of lateral amygdala and eventually suppress the excitability of the auditory cortex in rats following salicylate treatment, indicating the regulating effect of lateral amygdala to the auditory cortex in the tinnitus procedure. OBJECTIVE:To study the spontaneous firing ra...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.1080/00016489.2016.1204664

    authors: Song Y,Liu J,Ma F,Mao L

    更新日期:2016-12-01 00:00:00

  • Vestibular dysfunction causing instability in aged patients.

    abstract::Unilateral vestibular hypofunction (UVH) is a common vestibular dysfunction. Its influence upon the vestibulospinal reflex (VSR) is studied by posturography. The postural sway is disturbed when the VSR is disregulated because of the UVH. The degree of disturbance depends on the effectivity of the central compensation....

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.3109/00016488709109046

    authors: Norré ME,Forrez G,Beckers A

    更新日期:1987-07-01 00:00:00

  • Patients' perceptions of vocal problems: results from a survey in the Tokyo area.

    abstract::Laryngoscopy in cases of sulcus vocalis reveals bowed vocal folds, resulting in a spindle-shaped chink with glottal incompetence. The anatomic and functional problems and resulting incomplete glottal closure during phonation lead to the presenting symptoms of breathy hoarseness, decrease in maximum phonation time (MPT...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章,评审

    doi:10.3109/00016489.2014.999873

    authors: Tsunoda K,Fujimaki Y,Nito T,Yamasoba T,Tayama N,Makiyama K,Murofushi T,Tsunoda A,Ohshima K,Nishiyama K,Kano S,Niimi S

    更新日期:2015-06-01 00:00:00

  • The development of medial geniculate body in man: changes in the cholinesterase (CHE) activity during fetal and perinatal life.

    abstract::In the present study cholinesterase histochemical (ChE) techniques have been used to demonstrate differentiation and maturation of the medial geniculate body (MGB) in the human fetuses (ranging between 10.5 to 28 weeks) and infants (premature and three postnatal months). In the youngest specimens examined (10.5 to 15 ...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.3109/00016488309139464

    authors: Krmpotić-Nemanić J,Kostović I,Nemanić D

    更新日期:1983-05-01 00:00:00

  • Gait instability in patients with acoustic neuroma.

    abstract:OBJECTIVE:To investigate pathological gait in patients with unilateral acoustic neuroma using tactile sensors placed under both feet. MATERIAL AND METHODS:Forty-three patients were enrolled in the study. They were categorized into two groups: the small tumor group had tumors < 2 cm from the porus acousticus without an...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.1080/00016480310000566

    authors: Ishikawa K,Wang Y,Wong WH,Shibata Y,Itasaka Y

    更新日期:2004-05-01 00:00:00

  • Nasal problems in wood furniture workers. A study of symptoms and physiological variables.

    abstract::The occurrence of symptoms from the upper airways in the furniture industry was studied by means of a questionnaire which was answered by 676 wood furniture workers from 50 different factories. Twenty per cent reported nasal hypersecretion and 40% nasal obstruction. A randomized sample of 61 workers was investigated f...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.3109/00016488409107596

    authors: Wilhelmsson B,Drettner B

    更新日期:1984-11-01 00:00:00

  • The role of cholinergic transmission in outer hair cell functioning evaluated by distortion product otoacoustic emissions in myasthenic patients.

    abstract::Outer hair cells (OHCs) are the source of otoacoustic emissions, following a tropomyosin-miosin-dependent contraction, which are regulated by the olivocochlear bundle via the release of acetylcholine (ACh). ACh acts on ACh receptors (AChR) located on the OHC post-synaptic membrane. In myasthenia gravis (M.G.) neuromus...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.1080/000164801300043127

    authors: Paludetti G,Di Nardo W,D'Ecclesia A,Evoli A,Scarano E,Di Girolamo S

    更新日期:2001-01-01 00:00:00

  • Effect of chewing gum on static posturography in patients with balance disorders.

    abstract:CONCLUSION:The chewing gum indirectly affects postural control by influencing vestibular function to stabilize posture during upright standing. OBJECTIVES:This study aimed to evaluate the effect of chewing gum on static posturography in patients. METHODS:The subjects were 26 patients with chronic balance disorders. T...

    journal_title:Acta oto-laryngologica

    pub_type: 临床试验,杂志文章

    doi:10.3109/00016489.2011.607846

    authors: Goto F,Kushiro K,Tsutsumi T

    更新日期:2011-11-01 00:00:00

  • Thyroplasty type I (lateral compression) for dysphonia due to vocal cord paralysis or atrophy.

    abstract::Based on the experimental results of thyroplasty, thyroplasty type I which aims at medical shifting the vocal cord was performed on 8 patients with dysphonia, 6 with vocal cord paralysis and 2 with vocal cord atrophy. The surgery was conducted on either in- or out-patient basis and local anesthesia was used. Usually, ...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.3109/00016487509121353

    authors: Isshiki N,Okamura H,Ishikawa T

    更新日期:1975-11-01 00:00:00