Long-term treatment of nasal polyps with beclomethasone dipropionate aerosol. I. Treatment and rationale.

Abstract:

:Beclomethasone dipropionate is a potent corticosteroid, which when applied by a pressurized metered dose aerosol in the airways has pronounced anti-allergic effects with no risk of systemic steroid side effects at the recommended dosage. An impressive effect in hay fever and perennial rhinitis has been demonstrated. A double-blind short-term trial showed that the drug was effective in about 80% of patients suffering from moderate to severe nasal polyposis. A study of the long-term effects on the nasal mucosa is indicated.

journal_name

Acta Otolaryngol

journal_title

Acta oto-laryngologica

authors

Mygind N,Prytz S,Sorensen H,Pedersen CB

doi

10.3109/00016487609120897

subject

Has Abstract

pub_date

1976-09-01 00:00:00

pages

252-5

issue

3-4

eissn

0001-6489

issn

1651-2251

journal_volume

82

pub_type

临床试验,杂志文章
  • The inner laryngeal lymphatics. A lymphangioscopical and electron microscopical study.

    abstract::Lymphangioscopical and ultrastructural studies of the larynx reveal a lymphatic capillary and a collecting vessel system. Collecting vessels show luminal valves and elastic structural components within the wall. Lymphangioscopy reveals that a strict compartmentation of different laryngeal areas is unjustifiable with t...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.3109/00016488009127137

    authors: Beck C,Mann W

    更新日期:1980-03-01 00:00:00

  • Sinonasal cancer and exposure to softwood.

    abstract::In order to study the connection between occupation and sinonasal cancer we have reviewed the files and histological sections of 70 patients (24 females and 46 males) treated at the Department of Oto-rhino-laryngology, National Hospital of Norway. Detailed information concerning previous occupations was obtained by te...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.3109/00016488509119160

    authors: Voss R,Stenersen T,Roald Oppedal B,Boysen M

    更新日期:1985-01-01 00:00:00

  • Chronic subjective dizziness.

    abstract:CONCLUSION:Chronic subjective dizziness (CSD) is frequent and affects twice as many women as men. Anxiety is a strong predisposing factor. The pathophysiologic concept of this disorder assumes that balance function and emotion share common neurologic pathways, which might explain that the balance disorder can provoke f...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.1080/00016480701805455

    authors: Odman M,Maire R

    更新日期:2008-10-01 00:00:00

  • The effect of batroxobin on cochlear blood flow.

    abstract::Cochlear blood flow is considered to be closely related to cochlear function. Among several etiologic factors implicated in inner ear diseases, disturbance of local blood flow is held to be one of the most important. With this in view, various pharmaceuticals are currently being used to increase local blood flow in pa...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.3109/00016489209137500

    authors: Kawakami M,Makimoto K,Yamamoto H,Takahashi H

    更新日期:1992-11-01 00:00:00

  • Cough reflex induced by capsaicin inhalation in patients with dysphagia.

    abstract:CONCLUSIONS:We conclude that the capsaicin inhalation test is useful to directly assess cough reflex and sensation around the larynx, while it indirectly reflects central nervous system function. OBJECTIVES:To understand the state of the cough reflex before patients with dysphagia start eating. METHODS:We studied the...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.3109/00016489.2010.516013

    authors: Imoto Y,Kojima A,Osawa Y,Sunaga H,Fujieda S

    更新日期:2011-01-01 00:00:00

  • Histological reaction to polyimide films in the cochlea.

    abstract::The biocompatibility of commercially available polyimides was examined in relation to the sensory and neural structures of the cochlea. Thin films of four different polyimides were prepared as substrates for photolithographically produced scala tympani electrode arrays and implanted in 32 cat cochleae. Following at le...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.3109/00016488909127474

    authors: Haggerty HS,Lusted HS

    更新日期:1989-01-01 00:00:00

  • Endolymphatic duct blockage for refractory Ménière's disease: assessment of intraoperative CSF leak on short-term surgical outcomes.

    abstract:BACKGROUND:Endolymphatic sac decompression has shown limited success for the treatment of Ménière's disease (MD). We have published a novel technique with very promising results for the treatment of refractory MD: the Endolymphatic Duct Blockage (EDB) with two titanium clips. One of the challenges of this technique was...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.1080/00016489.2018.1481524

    authors: Saliba I,Asmar MH

    更新日期:2018-10-01 00:00:00

  • Spindle-cell tumours of the larynx: diagnostic pitfalls. A case report and review of the literature.

    abstract::Malignant laryngeal tumours with spindle-cell morphology are relatively rare. Differential diagnosis of spindle-cell carcinoma, leiomyosarcoma, fibrosarcoma, rhabdomyosarcoma, malignant melanoma and inflammatory myofibroblastic tumour may be particularly difficult. Ambiguous and indeterminate diagnoses are also possib...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.1080/0036554021000028070

    authors: Marioni G,Bottin R,Staffieri A,Altavilla G

    更新日期:2003-01-01 00:00:00

  • Study on the dye leakage response of nasal mucosa following topical, capsaicin challenge in guinea pigs.

    abstract::We examined the serial changes of intravenously applied dye leakage and preliminary examined histamine release into nasal lavage fluid after topical stimulation with capsaicin in guinea pigs. A significant increase in the dye leakage response was detected for 30-40 min, with the maximum response occurring between 5 an...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.3109/00016489209137438

    authors: Asakura K,Shirasaki H,Narita S,Kojima T,Kataura A

    更新日期:1992-01-01 00:00:00

  • Electrophysiological effects of multiple instillation of Haemophilus influenzae type b endotoxin on the inner ear.

    abstract::An analysis of auditory brainstem response (ABR) thresholds and ABR-based frequency tuning curves was performed in 15 Sprague-Dawley rats exposed to Haemophilus influenzae type b endotoxin; 5 microg/50 microl toxin was instilled every second day, altogether five times, into the middle ear cavity through a small perfor...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.3109/00016489709113406

    authors: Stenqvist M,Anniko M,Pettersson A

    更新日期:1997-05-01 00:00:00

  • Cross-platform data integration of paratubal electromyography and sonotubometry for eustachian tube: a pilot study.

    abstract:CONCLUSION:The sensitive sonotubometry and MATLAB provide a new tool to study the eustachian tube (ET) function and contribute more to reliable data and precise analysis. The levator veli palatini muscle (mLVP) and the salpingopharyngeus muscle (mSP) may, respectively, be the most important and least important muscle f...

    journal_title:Acta oto-laryngologica

    pub_type: 临床试验,杂志文章

    doi:10.1080/00016489.2016.1191672

    authors: Lin C,Li Y,Lin X,Zhang S,Tang A,Nong D

    更新日期:2016-11-01 00:00:00

  • Endoscope-assisted retrosigmoid keyhole approach for cerebellopontine angle: cadaveric study.

    abstract:CONCLUSION:A 20 mm hole made backwards from the midpoint of the asterion to the mastoid process is suitable for a retrosigmoid keyhole approach with the aid of an endoscope. The endoscope-assisted retrosigmoid keyhole approach can be considered an effective and safe method for removal of vestibular schwannoma. OBJECTI...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.3109/00016489.2013.817682

    authors: Sun JQ,Sun JW

    更新日期:2013-11-01 00:00:00

  • Aminotransferases in post-mortem cochlear fluids.

    abstract::Aspartate and alanine aminotransferase (ASAT, ALAT) activities were measured in human post-mortem sera, cerebrospinal fluid (CSF), perilymph and endolymph. Due to heart and/or liver morbidity during a terminal illness, the ASAT and ALAT serum activities were considerably increased as compared with normal and both were...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.3109/00016487609107478

    authors: Palva T,Nousiainen R,Raunio V

    更新日期:1976-01-01 00:00:00

  • Elemental composition of the mature inner ear.

    abstract::An X-ray energy dispersive analysis was performed on the mature serial sectioned freeze-dried mammalian labyrinth (CBA/CBA mouse). The elemental distribution in the endolymphatic and perilymphatic spaces revealed similar results as have been reported in the literature when withdrawing fluid for microanalysis. The cupu...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.3109/00016488009131744

    authors: Anniko M,Wroblewski R

    更新日期:1980-11-01 00:00:00

  • Penetration of erythromycin stearate into maxillary sinus mucosa and secretion in chronic maxillary sinusitis.

    abstract::The penetration of oral erythromycin stearate (Abboticin), administered in a dosage of 500 mg three times a day, into the maxillary sinus mucosa and secretion was studied in 15 patients (22 sinuses) operated on for chronic maxillary sinusitis. The average concentration in serum was 2.3 microgram/ml, 1.2 microgram/ml i...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.3109/00016487709123970

    authors: Paavolainen M,Kohonen A,Palva T,Renkonen OV

    更新日期:1977-09-01 00:00:00

  • Partial deafness cochlear implantation provides benefit to a new population of individuals with hearing loss.

    abstract:CONCLUSION:Partial deafness cochlear implantation (PDCI) is a feasible means of treating individuals who have good low frequency hearing, but a severe to profound hearing loss in the mid to high frequencies. The individuals have benefit in noise and show significant benefit in a number of difficult listening conditions...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.1080/00016480600606632

    authors: Skarzynski H,Lorens A,Piotrowska A,Anderson I

    更新日期:2006-09-01 00:00:00

  • Autonomic nerves and middle ear fluid production. An experimental study in the rat.

    abstract::The production of middle ear effusion by mechanical stimulation was studied in sympathectomized and vagotomized animals. Mechanical stimulation was obtained by a 14 degree C airstream in the external auditory canal. In sympathectomized animals this procedure caused effusion production and vasoconstriction of pars flac...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.3109/00016488809107365

    authors: Goldie P,Hellström S

    更新日期:1988-07-01 00:00:00

  • Colonization by Haemophilus influenzae and group A streptococci in recurrent acute tonsillitis and in tonsillar hypertrophy.

    abstract::One hundred patients subjected to tonsillectomy because of recurrent acute tonsillitis or tonsillar hypertrophy were evaluated bacteriologically both with ordinary throat culturing and cultures from tonsillar cores. In 26% of the patients H. influenzae was isolated and in 20% beta-haemolytic group A streptococci. Grow...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.3109/00016489009107448

    authors: Stjernquist-Desatnik A,Prellner K,Schalén C

    更新日期:1990-03-01 00:00:00

  • Prediction of upper respiratory tract bacteria in acute otitis media.

    abstract:CONCLUSIONS:Thorough otomicroscopical examination of the tympanic membrane in acute otitis media (AOM) might distinguish AOM episodes caused by different bacteria. It thus might be a way to select appropriate treatment for each patient without raising the number of dangerous complications. OBJECTIVES:The aim of this s...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.1080/00016480601091719

    authors: Foglé-Hansson M,White P,Hermansson A

    更新日期:2007-09-01 00:00:00

  • A comparison of the furosemide and glycerol tests for Meniere's disease. With special reference to the bilateral lesion.

    abstract::The feasibility of furosemide test for the detection of endolymphatic hydrops has previously been discussed (Authors, 1973, 1975). The glycerol test also has been reported as being effective for the same purpose but only in Meniere patients with fluctuating hearing loss (Klockhoff & Lindblom, 1966). In 48 patients wit...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.3109/00016487709128845

    authors: Futaki T,Kitahara M,Morimoto M

    更新日期:1977-03-01 00:00:00

  • A daily nasal spray with saline prevents symptoms of rhinitis.

    abstract:OBJECTIVE:To ascertain whether a daily nasal spray with physiological saline could prevent symptoms of common cold in a population of otherwise healthy adults. MATERIAL AND METHODS:This was study involving 10 weeks of daily use of a nasal saline spray and 10 weeks of only recording symptoms. Young adults eligible for ...

    journal_title:Acta oto-laryngologica

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1080/00016480410017657

    authors: Tano L,Tano K

    更新日期:2004-11-01 00:00:00

  • Expression patterns of Nedd4 isoforms and SGK1 in the rat cochlea.

    abstract:CONCLUSION:Our findings suggest that there exists a Na(+) transport system in the cochlea consisting of SGK1, Nedd4 isoforms and ENaC, which may work in concert to transport Na(+) and to maintain homeostasis in the inner ear as they do in other tight epithelia. OBJECTIVES:It has been well demonstrated that the epithel...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.1080/00016480802552501

    authors: Zhong SX,Liu ZH

    更新日期:2009-09-01 00:00:00

  • An evaluation of normal strial capillary transport using the electron-opaque tracers ferritin and iron dextran.

    abstract::Enzymatic tracer techniques to study normal and pathologic strial capillary transport pose various problems. The use of electron opaque tracers can circumvent many of these problems. Iron dextran (mol. diam 20--70 A) and ferritin (mol. diam 110 A) were injected intravenously and the mice sacrificed at intervals of 1/2...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.3109/00016488009127103

    authors: Santos-Sacchi J,Marovitz WF

    更新日期:1980-01-01 00:00:00

  • Acute hearing loss in patients with hematological disorders.

    abstract:OBJECTIVE:This study adopted an inner ear test battery to investigate the causes of acute sensorineural hearing loss in patients with hematological disorders. METHODS:During the past 20 years, the authors have experienced 14 patients with hematological disorders, i.e. leukemia or aplastic anemia, having acute sensorin...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.3109/00016489.2015.1015608

    authors: Lin CT,Chiang CW,Young YH

    更新日期:2015-07-01 00:00:00

  • Gravity load related asymmetries in the sagittal vestibulo-collic reflex.

    abstract::EMG recordings of the neck muscles (biventer cervicis, complexus, splenius, longus capitis) of decerebrate cats were obtained during pitch and roll stimulations (sinusoidal stimulation: 30 degrees p-p amplitude, 0.2 Hz frequency). Most of the EMG responses to pitch showed activation peaks leading the position stimuli ...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.3109/00016489309135800

    authors: Pettorossi VE,Santarelli R,Draicchio F,Errico P,Ferraresi A

    更新日期:1993-05-01 00:00:00

  • Follow-up vestibular examination in Menière's disease.

    abstract::A retrospective study was carried out on repeated audio-vestibular examinations in 53 patients with unilateral Meniere's disease, between the vertiginous spells. Most patients showed no change in the caloric response reduction of the afflicted ear in the subsequent tests compared with the first one. These patients had...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.3109/00016488109133278

    authors: Hulshof JH,Baarsma EA

    更新日期:1981-11-01 00:00:00

  • Angiogenesis from the eighth cranial nerve to vestibular schwannomas.

    abstract::Vascularization between vestibular schwannomas and the adjacent eighth cranial nerve was examined in order to elucidate the angiogenic effect of these tumours. Specimens from 12 patients were examined by light microscopy and immunohistochemistry (series 1), while specimens from another 17 patients were examined by lig...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.3109/00016489609137712

    authors: Matsunaga T,Kanzaki J,Hosoda Y

    更新日期:1996-01-01 00:00:00

  • Primary non-Hodgkin's lymphoma of the nasal cavity. Clinical case report and discussion.

    abstract::Primary non-Hodgkin's lymphoma of the nasal cavity is a disease more likely to affect men than women; it is characterized by a T cell immunophenotype and is often associated with involvement of the paranasal structures and with high recurrence rates. Many authors report that its extremely poor prognosis depends on tum...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.1080/000164800750046081

    authors: Cavalot AL,Ricci E,Nazionale G,Palonta F,Fadda GL

    更新日期:2000-06-01 00:00:00

  • Bone resorption in chronic otitis media. A light-microscopical and histochemical investigation of acid phosphatase activity.

    abstract::As a continuation of our previous work, where we have demonstrated that in chronic otitis media the picture in the submucosa-bone marginal zone is dominated by capillary proliferation and occurrence of a mononuclear, histiocyte-like cell containing lysosome-like cytoplasmatic bodies, we now report the presence of cons...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.3109/00016487509124704

    authors: Thomsen J,Bretlau P,Kristensen HK

    更新日期:1975-05-01 00:00:00

  • Role of alcohol and smoking in diagnostic delay of head and neck cancer patients.

    abstract:CONCLUSIONS:This study shows that heavy drinking is a risk factor for prolonged delay in presenting with head and neck cancer and for presenting with a large tumour in the head and neck region. Excessive smoking is only a risk factor for being diagnosed with a large tumour, although there is a weak association between ...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章

    doi:10.1080/00016480510028456

    authors: Brouha X,Tromp D,Hordijk GJ,Winnubst J,De Leeuw R

    更新日期:2005-05-01 00:00:00