Topical treatment with growth factors for tympanic membrane perforations: progress towards clinical application.

abstract：OBJECTIVE:Acquired centralized tinnitus (ACT) is the most frequent type of chronic tinnitus. We introduce a cognitive neurophysiological ACT hypothesis based on centralized cognitive sensitization processes. MATERIAL AND METHODS:Published cognitive sensitization processes were reviewed using PubMed. Furthermore, a Coc...

journal_title：Acta oto-laryngologica

authors： Zenner HP,Zalaman IM

更新日期：2004-05-01 00:00:00

abstract：CONCLUSION:We report a distinct pattern of tongue movement. This is interpreted as a compensatory mechanism after hypopharyngo-laryngectomy with reconstruction using a jejunal autograft. Passage through the oesophagus is mainly passive. OBJECTIVE:Swallowing is normally initiated voluntarily, and afterwards presumed to...

journal_title：Acta oto-laryngologica

authors： Bakkan N,Boysen ME,Line PD,Aasen S

更新日期：2010-09-01 00:00:00

abstract：:Background: The management of patients with tinnitus who receive middle ear surgery has not been established.Aims: The aim of this study is (1) how many patients who receive middle ear surgery have tinnitus and (2) how educational counselling and middle ear surgery is effective with consistent tinnitus.Subjects and me...

journal_title：Acta oto-laryngologica

authors： Kanzaki S,Ogawa K

更新日期：2020-04-01 00:00:00

abstract：BACKGROUND:The most crucial clinical problem of Eosinophilic Otitis Media (EOM) is sensorineural hearing loss. A previous report revealed that repeated antigen stimulation of middle ear causes eosinophilic inflammation not only in the middle ear but also in the inner ear. OBJECTIVE:The purpose of the present study was...

journal_title：Acta oto-laryngologica

authors： Kudo N,Matsubara A,Nishizawa H,Miura T

更新日期：2017-05-01 00:00:00

abstract：:[3H]Dihydrostreptomycin was given intramuscularly to young pigmented guinea pigs and rats. Whole-body autoradiography, combined with densitometric measurement of the blackening of the autoradiograms, and liquid scintillation counting were used to determine the levels of radioactivity in the inner ear in relation to bl...

journal_title：Acta oto-laryngologica

authors： Nilsson Tammela M,Tjälve H

更新日期：1986-03-01 00:00:00

abstract：CONCLUSION:A new murine model for the study of Ménière's disease has been developed by treatment with both lipopolysaccharide (LPS) and aldosterone. Induction of vestibular dysfunction in the hydropic animal model may entail additional stress such as reduced inner ear blood flow, and sudden acute changes in endolymph v...

journal_title：Acta oto-laryngologica

authors： Takumida M,Akagi N,Anniko M

更新日期：2008-03-01 00:00:00

abstract：:The possible beneficial effects of carbogen gas (95% O2/5% CO2) inhalation on noise-induced permanent cochlear impairment were investigated. Groups of guinea pigs were exposed to daily 3 1/2-hour presentations of 120 dB of broad-band noise in an atmosphere of either carbogen gas or normal air. Other groups received ca...

journal_title：Acta oto-laryngologica

authors： Brown JJ,Vernon JA,Fenwick JA

更新日期：1982-05-01 00:00:00

abstract：CONCLUSION:The results of this study suggest that treatment with radical scavengers has the potential to become an effective new therapy for age-related hearing loss. OBJECTIVE:To assess the efficacy of treatment with radical scavengers for age-related hearing loss. SUBJECTS AND METHODS:Rebamipide (300 mg/day), alpha...

journal_title：Acta oto-laryngologica

authors： Takumida M,Anniko M

更新日期：2009-01-01 00:00:00

abstract：:The maintenance of upright stance in humans requires the integrative evaluation of vestibular, visual, and proprioceptive information. Recent experiments prove the existence of fast vestibulo-spinal reactions in humans. Their physiological significance for the compensation of sudden external displacements of the body ...

journal_title：Acta oto-laryngologica

authors： Dichgans J,Diener HC

更新日期：1989-05-01 00:00:00

abstract：OBJECTIVE:The aim of this double-blind, randomized, multicenter study was to compare the efficacy of betahistine dihydrochloride (BH) and flunarizine (FL) using the Dizziness Handicap Inventory (DHI), a validated self-assessment questionnaire that has not previously been used in a clinical trial to evaluate antivertigo...

journal_title：Acta oto-laryngologica

authors： Albera R,Ciuffolotti R,Di Cicco M,De Benedittis G,Grazioli I,Melzi G,Mira E,Pallestrini E,Passali D,Serra A,Vicini C

更新日期：2003-06-01 00:00:00

abstract：:Vestibular microphonics in response to acoustical stimulation were recorded in cochlea-deprived pigeons. Endolymph flow in the semicircular canals alters this response. A caloric stimulus was applied to the horizontal canal or the posterior vertical canal close to the ampulla. To minimize the influence of gravity, the...

journal_title：Acta oto-laryngologica

authors： Wit HP,Segenhout JM

更新日期：1988-03-01 00:00:00

abstract：:Five out of eight consecutive cases with initial symptoms of a 'midline granuloma' were identified as malignant histiocytosis (histiocytic sarcoma) which within 5 months to 4 years led to generalization and death. The three remaining cases also fulfilled the morphological criteria of this type of neoplasia, though the...

journal_title：Acta oto-laryngologica

authors： Laeng H,Gerber H,Mueller J

更新日期：1986-01-01 00:00:00

abstract：:Metal intoxication (mercury and arsenic) in guinea pigs may cause damage to labyrinthine blood vessels by swelling of the endothelial cells, mitochondrial disintegration and sometimes protrusion of endothelial cell cytoplasm herniating into the blood vessel lumen. Chronic mercury intoxication resulted in distorted end...

journal_title：Acta oto-laryngologica

authors： Anniko M,Sarkady L

更新日期：1977-05-01 00:00:00

abstract：:The fear of destroying an anticipated growth centre has, with time, induced the postponement of nasal septal operations until adult age. Underdevelopment of the nose and middle face is otherwise believed to be the long-term result. In order to test this hypothesis, subepichondrial surgery was performed in growing dome...

journal_title：Acta oto-laryngologica

authors： Freng A,Haye R

更新日期：1985-09-01 00:00:00

abstract：OBJECTIVE:Proteomic analysis with 2D electrophoresis and matrix-assisted laser desorption and ionization time-of-flight mass spectrometry (MALDI-TOF MS) may be a powerful tool for identifying and characterizing the specific proteins relating to the pathogenesis of some diseases, including cholesteatoma. The purpose of ...

journal_title：Acta oto-laryngologica

authors： Kim JL,Jung HH

更新日期：2004-09-01 00:00:00

abstract：:The blowing of chilled (14 degrees C) air into the external auditory canal (EAC) resulted in a profuse middle ear fluid production. The stimulation caused marked changes in the pars flaccida of the tympanic membrane. A slight vasodilatation was noted in the oedematous loose connective tissue layer of the pars flaccida...

journal_title：Acta oto-laryngologica

authors： Goldie P,Hellström S

更新日期：1986-09-01 00:00:00

abstract：CONCLUSION:Our results suggest that patients with migraine or tension-type headache have subclinical deviations of the subjective visual vertical, which may be associated with their subjective imbalance. OBJECTIVES:Patients affected by migraine or tension-type headache often complain of unsteadiness. However, they rar...

journal_title：Acta oto-laryngologica

authors： Asai M,Aoki M,Hayashi H,Yamada N,Mizuta K,Ito Y

更新日期：2009-01-01 00:00:00

abstract：:The present paper presents monopolar recording of facial nerve antidromic potentials as an alternative technique to facial electromyography for the continuous monitoring of the facial nerve during acoustic neuroma surgery. The investigation involved 22 patients undergoing acoustic neuroma surgery via a retrosigmoid ap...

journal_title：Acta oto-laryngologica

authors： Colletti V,Fiorino F,Policante Z,Bruni L

更新日期：1997-09-01 00:00:00

abstract：:Cell proliferation in the endolymphatic sac (ES) after immunostimulation was assessed immunohistochemically. Guinea pigs were employed as experimental animals and keyhole limpet hemocyanin was used as the antigen. After i.p. injection of 5-bromo-2'-deoxyuridine (BrdUrd), the BrdUrd+ cells were counted to assess the nu...

journal_title：Acta oto-laryngologica

authors： Takahashi M,Tomiyama S

更新日期：1995-05-01 00:00:00

abstract：OBJECTIVE:To quantitatively analyze modifications of the paratubal muscles in developing Wistar rats following nasal obstruction. MATERIAL AND METHODS:Twenty-four Wistar rats were used. Twelve were examined at 6, 8 and 12 weeks after birth and were considered normal controls. The nostrils of the remaining 12 rats were...

journal_title：Acta oto-laryngologica

authors： Scarano E,Fetoni AR,Picciotti P,Cadoni G,Galli J,Paludetti G

更新日期：2003-01-01 00:00:00

abstract：:Immunological mechanisms are thought to play an important role in the pathogenesis of some cochleo-vestibular diseases. This study attempts to present further evidence of autoantibodies reactive against guinea pig inner ear proteins found in patients with autoimmune inner ear diseases (AIED) and specifically identifie...

journal_title：Acta oto-laryngologica

authors： Boulassel MR,Deggouj N,Tomasi JP,Gersdorff M

更新日期：2001-01-01 00:00:00

abstract：:Background: It has been reported that head-up sleep (HUS) prevents free-floating otoliths from entering canals and that vertical recognition training (VRT) promotes vestibular compensation.Aims/objectives: We would like to assess HUS and VRT for intractable motion-evoked dizziness, including possible benign paroxysmal...

journal_title：Acta oto-laryngologica

authors： Kitahara T,Horinaka A,Shiozaki T,Ito T,Wada Y,Yamanaka T,Nario K

更新日期：2020-06-01 00:00:00

abstract：:By means of cleaving the soft palate and blocking the Eustachian tube, two otomicroscopically well defined types of otitis media, serous and purulent, were created in an animal model (rat). The microbiological pattern of these conditions were characterized at 1, 2, 3, 4 and 6 weeks after the onset. Samples were collec...

journal_title：Acta oto-laryngologica

authors： Johansson U,Hellström S

更新日期：1990-07-01 00:00:00

abstract：:Characteristic patterns of laryngeal dysfunction due to central neurologic disease are documented by 16 mm ciné photography. Representative patients are used to describe typical patterns of abnormal laryngeal function which occur in upper motor neuron, extrapyramidal, cerebellar, nuclear and mixed foci of lesions. The...

journal_title：Acta oto-laryngologica

authors： Ward PH,Hanson DG,Berci G

更新日期：1981-05-01 00:00:00

abstract：CONCLUSION:Given the phonetic balancing across lists and the validation with spectrally degraded speech, the present Mandarin disyllable recognition test (DRT) materials may be useful for assessing speech performance of Mandarin-speaking cochlear implant (CI) users. If combined with the previously developed sentence ma...

journal_title：Acta oto-laryngologica

authors： Zhu M,Wang X,Fu QJ

更新日期：2012-08-01 00:00:00

abstract：:Cells can die by two distinct pathways: apoptosis and necrosis. To explore whether intense noise can induce hair cell (HC) death via the apoptotic pathway, we systematically examined morphological changes in guinea pig cochlear HC nuclei stained with Hoechst 33342, a fluorescent dye specifically labelling the nuclear ...

journal_title：Acta oto-laryngologica

authors： Hu BH,Guo W,Wang PY,Henderson D,Jiang SC

更新日期：2000-01-01 00:00:00

abstract：:Background: Amyloidosis is a benign, slowly progressive disease. However, the treatment of laryngeal amyloidosis (LA) has not been studied systematically.Objectives: To investigate the treatment results of cold micro forceps or carbon dioxide laser under microlaryngoscope in the treatment of LA.Methods: A retrospectiv...

journal_title：Acta oto-laryngologica

authors： Wu X,Zhang J,Wei C

更新日期：2019-12-01 00:00:00

abstract：:Macrolides have been used for decades as an important chemotherapeutic agent in the treatment of infectious diseases. In the last 10 years there has also been increasing interest in the interaction between macrolide antibiotics and the immune system. The aim of this review is to focus on the anti-inflammatory action o...

journal_title：Acta oto-laryngologica

authors： Cervin A

更新日期：2001-01-01 00:00:00

abstract：:Racial differences in the size, shape and structure of the cranium exist. This paper evaluates the importance of race in influencing the required sizes of craniotomies for gaining access to the lateral end of the internal auditory meatus without breaching the labyrinth via the retrosigmoid approach. Fine-cut CT scans ...

journal_title：Acta oto-laryngologica

authors： Low WK,Fenton JE,Fagan PA,Gibson WP

更新日期：1995-11-01 00:00:00

abstract：:The purpose of this study was to show the early stages of polyp formation, as part of our studies on the pathogenesis of nasal polyps. Two and 4 weeks after experimental tubal occlusion in 18 Wistar rats, 13 showed signs of bacterial infection, respective acute otitis media. In the majority of these rats polypouslike ...

journal_title：Acta oto-laryngologica

authors： Larsen PL,Tos M

更新日期：1991-01-01 00:00:00