Abstract:
:In this experimental study in the rat, compound 48/80--a potent degranulating drug of mast cells--was instilled in the external auditory meatus towards the tympanic membrane. Moreover, effusion material was produced in the attic space by blocking the tympanic isthmus with a piece of Gelfoam applied through the tympanic bulla. Both these procedures caused a degranulation of the pars flaccida mast cells and subsequently histamine was detected in the rinsing fluid collected from the middle ear cavity. A possible direct cause of the effusion material in the middle ear cavity may be a degranulation of the pars flaccida mast cells, thus resembling an allergic reaction Type I.
journal_name
Acta Otolaryngoljournal_title
Acta oto-laryngologicaauthors
Alm PE,Bloom GD,Hellström S,Salén B,Stenfors LEdoi
10.3109/00016488209128942subject
Has Abstractpub_date
1982-11-01 00:00:00pages
517-22issue
5-6eissn
0001-6489issn
1651-2251journal_volume
94pub_type
杂志文章abstract:CONCLUSION:This study demonstrated differential gene expression profiles in salicylate ototoxicity with oligonucleotide microarray. This study may also provide basic information on candidate genes associated with hearing loss and/or tinnitus or recovery after salicylate-induced cochlear dysfunction. OBJECTIVES:Salicyl...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016480600801365
更新日期:2007-05-01 00:00:00
abstract::Malignant laryngeal tumours with spindle-cell morphology are relatively rare. Differential diagnosis of spindle-cell carcinoma, leiomyosarcoma, fibrosarcoma, rhabdomyosarcoma, malignant melanoma and inflammatory myofibroblastic tumour may be particularly difficult. Ambiguous and indeterminate diagnoses are also possib...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/0036554021000028070
更新日期:2003-01-01 00:00:00
abstract:CONCLUSION:Endolymphatic hydrops could be a reversible inner ear pathological condition. After sac surgery, hydrops was reduced and symptoms went into remission in some cases, although vertigo suppression was not always a result of the reduced hydrops. OBJECTIVE:To examine the changes in endolymphatic hydrops detected...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489.2013.795290
更新日期:2013-09-01 00:00:00
abstract:OBJECTIVES:Hearing loss after spinal anesthesia has been reported to be related to the transmission of a reduced subarachnoid pressure to the inner ear via the cochlear aqueduct due to loss of spinal fluid. However, there are also some controversies related to this phenomenon, which require systematic investigation. M...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016480410017143
更新日期:2004-12-01 00:00:00
abstract::Background: Various graft materials and surgical methods are used in the treatment of tympanic membrane perforations.Aims/Objectives: The aim of this study was to evaluate the operation method and graft success of extended perichondrial butterfly myringoplasty performed by an endoscopic method and the hearing gain of ...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016489.2020.1730949
更新日期:2020-04-01 00:00:00
abstract::Racial differences in the size, shape and structure of the cranium exist. This paper evaluates the importance of race in influencing the required sizes of craniotomies for gaining access to the lateral end of the internal auditory meatus without breaching the labyrinth via the retrosigmoid approach. Fine-cut CT scans ...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489509139402
更新日期:1995-11-01 00:00:00
abstract:CONCLUSION:Changes in the metabolism of arachidonic acid (AA) might be part of a noise-induced compensatory mechanism with regional specificity. OBJECTIVES:The released imbalance of prostaglandins and leukotrienes, both AA metabolites, might result in altered blood flow regulation in the inner ear and probably contrib...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016480903168066
更新日期:2010-03-01 00:00:00
abstract:CONCLUSION:Although this study did not show higher risk of oropharyngeal malignancy in HIV patients overall, they still had much higher prevalence of NHL as well as HL than HIV negative patients. Presence of cervical lymphadenopathy is unreliable in differentiating malignant oropharyngeal tumours from benign lymphoid h...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489.2016.1170878
更新日期:2016-09-01 00:00:00
abstract::[3H]Dihydrostreptomycin was given intramuscularly to young pigmented guinea pigs and rats. Whole-body autoradiography, combined with densitometric measurement of the blackening of the autoradiograms, and liquid scintillation counting were used to determine the levels of radioactivity in the inner ear in relation to bl...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016488609132834
更新日期:1986-03-01 00:00:00
abstract::In experiments on 11 dogs, the authors attempted to develop a method for avoiding serious complications following simultaneous bilateral radical neck dissection. Both internal jugular veins were resected; one vein was reconstructed with the autologous v. femoralis. Blood flow in the reconstructed vein was normal in th...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016488409132914
更新日期:1984-05-01 00:00:00
abstract::Using primary cultures of marginal cells of stria vascularis from guinea pig and gerbil, ionic channels located on the luminal membrane were investigated by means of patch clamp technique. Recordings were performed in cell-attached and inside-out configurations. In cell-attached configuration, single channel activity ...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489109137391
更新日期:1991-01-01 00:00:00
abstract:CONCLUSION:The addition of transoral robotic surgery (TORS) in the diagnostic management of patients classified with head and neck squamous cell carcinoma of unknown primary (SCCUP) is promising and appears to improve detection rates of the primary tumour. The approach presented in this first Scandinavian study could p...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489.2015.1052983
更新日期:2015-01-01 00:00:00
abstract::In 12 healthy volunteers, and 5 prelingually and 5 postlingually profoundly deaf subjects, a 500 Hz filtered click stimulus was applied to the mastoid via the bone conductor. In all the healthy volunteers, middle latency response (MLR) was recorded. Among all profoundly deaf subjects, MLR was recorded only in 2 with p...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016488509108929
更新日期:1985-03-01 00:00:00
abstract::Normal quantum type bone remodeling was studied in temporal bones of young domestic pigs by means of combined microradiography, osteofluorochrome labelling and osteoid staining. Evolving secondary osteons were morphologically normal although much less in the otic capsule than in the surrounding compacta of the tempora...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489009122540
更新日期:1990-09-01 00:00:00
abstract::Background: Frequency-specific hearing studies are important for predicting hearing results and the prognosis after stapes surgery, to prepare for the rehabilitation of frequency-specific hearing in patients with otosclerosis.Objectives: To evaluate outcomes of stapes surgery of Chinese otosclerosis patients with diff...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016489.2020.1724331
更新日期:2020-05-01 00:00:00
abstract::Background: Recurrent respiratory papillomatosis (RRP) remains a challenging and frustrating disease to treat.Objective: To explore the efficacy of microsurgery in combined with Topical-PDT in treating recurrent respiratory papillomatosis.Materials and methods: Fifty patients with RRP were treated with microsurgery in...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016489.2019.1667530
更新日期:2019-12-01 00:00:00
abstract::Background: The management of patients with tinnitus who receive middle ear surgery has not been established.Aims: The aim of this study is (1) how many patients who receive middle ear surgery have tinnitus and (2) how educational counselling and middle ear surgery is effective with consistent tinnitus.Subjects and me...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016489.2020.1713397
更新日期:2020-04-01 00:00:00
abstract:BACKGROUND:As tympanotomy using the transcanal approach was a routine surgical technique for traumatic ossicular disruption, the efficacy of the posterior tympanum approach was rarely explored. AIM:This study aimed to investigate whether the hearing outcomes improved after simultaneous ossiculoplasty and facial nerve ...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016489.2020.1833081
更新日期:2020-11-05 00:00:00
abstract::Macrolides have been used for decades as an important chemotherapeutic agent in the treatment of infectious diseases. In the last 10 years there has also been increasing interest in the interaction between macrolide antibiotics and the immune system. The aim of this review is to focus on the anti-inflammatory action o...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章,评审
doi:10.1080/000164801300006326
更新日期:2001-01-01 00:00:00
abstract::An experimental model of sinusitis in the rabbit was developed, using type 3 pneumococci. The superior parts of the rabbit maxillary sinuses were surgically exposed and the maxillary ostium was unilaterally blocked. The following day a challenge dose of 10(7)-10(9) colony-forming units of Streptococcus pneumoniae, cap...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:
更新日期:1987-05-01 00:00:00
abstract::The view current over the last 60 years or so that coniotomy often leads to subglottic stenosis has recently been called into question. In the present study 103 electively performed coniotomies have been analysed. The operation was found to be much easier than tracheotomy. There was no case of severe peroperative or p...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016488309132905
更新日期:1983-09-01 00:00:00
abstract::In human temporal bone specimens the vibrations of the labyrinthine fluid were measured by a piezoelectric system after application of various techniques of otosclerosis surgery. Compared with the amplitude in the case of a normal stapes, the surgical techniques according to Zangemeister, Shea and Schuknect resulted i...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016487509124656
更新日期:1975-01-01 00:00:00
abstract:OBJECTIVE:This study adopted an inner ear test battery to investigate the causes of acute sensorineural hearing loss in patients with hematological disorders. METHODS:During the past 20 years, the authors have experienced 14 patients with hematological disorders, i.e. leukemia or aplastic anemia, having acute sensorin...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489.2015.1015608
更新日期:2015-07-01 00:00:00
abstract:BACKGROUND:The most crucial clinical problem of Eosinophilic Otitis Media (EOM) is sensorineural hearing loss. A previous report revealed that repeated antigen stimulation of middle ear causes eosinophilic inflammation not only in the middle ear but also in the inner ear. OBJECTIVE:The purpose of the present study was...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016489.2016.1266508
更新日期:2017-05-01 00:00:00
abstract:INTRODUCTION:This study showed that short and long interval treatments achieved comparable success rates. There was no statistically significant difference in the rate of early and late recurrences between the two groups. Modified Epley maneuver can be applied in a short interval time with comparable success and recurr...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016489.2016.1252852
更新日期:2017-05-01 00:00:00
abstract::45CaCl2 was injected into gerbils in single or multiple doses, and the resulting radioactivity in serum, otoconial CaCO3, bone samples, and selected labyrinthine epithelium was determined by liquid scintillation spectrometry. Incorporation into both utricular and saccular otoconia occurred at the rate of 0.06-0.07 nmo...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016487509121327
更新日期:1975-09-01 00:00:00
abstract::Background: It has been reported that head-up sleep (HUS) prevents free-floating otoliths from entering canals and that vertical recognition training (VRT) promotes vestibular compensation.Aims/objectives: We would like to assess HUS and VRT for intractable motion-evoked dizziness, including possible benign paroxysmal...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016489.2020.1727566
更新日期:2020-06-01 00:00:00
abstract:INTRODUCTION:Bilateral cochlear implants are seen to improve hearing capabilities. OBJECTIVE:To assess the auditory outcome of paediatric bilateral cochlear implant in Universiti Kebangsaan Malaysia. MATERIALS AND METHODS:This was a cross-sectional and descriptive study single centre analysis. Categories of Auditory ...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016489.2020.1775887
更新日期:2020-10-01 00:00:00
abstract:OBJECTIVES:In this paper we test the concept of combining electrical stimulation for high-frequency sound with acoustic hearing for low-frequency information in the same ear. In addition, we test whether residual hearing can be preserved when an electrode is placed up to 10 mm into the inner ear, and whether the site o...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016480410016423
更新日期:2004-05-01 00:00:00
abstract:CONCLUSION:The age-related changes in ocular vestibular-evoked myogenic potentials (oVEMPs) elicited by galvanic vestibular stimulation (GVS) and bone-conducted vibration (BCV) might be attributed to the morphological degeneration of the vestibular system. OBJECTIVE:This study employed GVS and BCV modes for eliciting ...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489.2012.708437
更新日期:2012-12-01 00:00:00