Acute hearing loss in patients with hematological disorders.


OBJECTIVE:This study adopted an inner ear test battery to investigate the causes of acute sensorineural hearing loss in patients with hematological disorders. METHODS:During the past 20 years, the authors have experienced 14 patients with hematological disorders, i.e. leukemia or aplastic anemia, having acute sensorineural hearing loss. An inner ear test battery comprising audiometry and cervical vestibular-evoked myogenic potential (cVEMP), ocular VEMP (oVEMP), and caloric tests was performed. RESULTS:Diagnoses comprised of sudden sensorineural hearing loss in 12 patients and endolymphatic hydrops in four patients (two patients had one ear with sudden sensorineural hearing loss while the other ear had endolymphatic hydrops). Percentages of recruitment phenomenon showed a significant difference between endolymphatic hydrops and sudden sensorineural hearing loss. Abnormal percentages for mean hearing level (86%), cVEMP test (71%), oVEMP test (25%), and caloric test (14%) exhibited a significant sequential decline in these patients. CONCLUSION:Acute sensorineural hearing loss in a patient with leukemia or aplastic anemia may be related to either sudden sensorineural hearing loss or endolymphatic hydrops. A significant sequential decline in the function of the cochlea, saccule, utricle, and semicircular canals indicates that the pars inferior is more vulnerable to blood insult than the pars superior.


Acta Otolaryngol


Acta oto-laryngologica


Lin CT,Chiang CW,Young YH




Has Abstract


2015-07-01 00:00:00












  • Transforming growth factor beta 1 genotype and p16 as prognostic factors in head and neck squamous cell carcinoma.

    abstract:CONCLUSION:Transforming growth factor β1 gene (TGFβ1) genotype is a potential p16 independent prognostic factor predicting response to chemoradiotherapy in head and neck squamous cell carcinoma (HNSCC). OBJECTIVES:Expression of p16 and epidermal growth factor receptor (EGFR) has been reported to be associated with sur...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章


    authors: Lundberg M,Leivo I,Saarilahti K,Mäkitie AA,Mattila PS

    更新日期:2012-09-01 00:00:00

  • Effects of short inter-stimulus intervals on olfactory and trigeminal event-related potentials.

    abstract:CONCLUSION:Chemosensory event-related potentials (CSERPs) were identified in all measurements using the 20 s and the 10 s inter-stimulus interval (ISI) protocol, reducing the recording time to 75% or 57% compared with the standard protocol. A possible explanation for the rising CSERP amplitudes by shortening the ISI in...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章


    authors: Kassab A,Schaub F,Vent J,Hüttenbrink KB,Damm M

    更新日期:2009-11-01 00:00:00

  • Histological evaluation of novel ossicular chain replacement prostheses: an animal study in rabbits.

    abstract:CONCLUSION:The improved biocompatibility of Bioverit II coated with a nanostructured surface shows promising qualities for use in human reconstructive middle ear surgery. In the case of chitosan-hydroxyapatite composite prostheses, further investigations regarding composition of the material, degree of purity and desig...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章


    authors: Turck C,Brandes G,Krueger I,Behrens P,Mojallal H,Lenarz T,Stieve M

    更新日期:2007-08-01 00:00:00

  • Effects of Semont maneuver on benign paroxysmal positional vertigo: a meta-analysis.

    abstract:BACKGROUND:Benign paroxysmal positional vertigo (BPPV) is the most common type of peripheral vertigo. This study aimed to evaluate the effects of the Semont maneuver (SM) for BPPV treatment, compared with other methods. METHODS:Studies were selected in relevant databases under pre-defined criteria up to June 2015. The...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章,meta分析


    authors: Zhang X,Qian X,Lu L,Chen J,Liu J,Lin C,Gao X

    更新日期:2017-01-01 00:00:00

  • Auditory brainstem evoked responses in the clinical evaluation and follow-up of insulin-dependent diabetic subjects.

    abstract::In the last few years the use of ABR in the dysmetabolic encephalopathies has aroused considerable interest. Even though brainstem involvement in these syndromes is not yet entirely understood, ABR techniques have provided new and important insights. We studied 60 insulin-dependent diabetic subjects, 29 females and 31...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章


    authors: Martini A,Comacchio F,Fedele D,Crepaldi G,Sala O

    更新日期:1987-05-01 00:00:00

  • Immunohistochemical analysis of EGFR and hyaluronan in tongue cancer and the development of regional recurrence in patients initially diagnosed N0.

    abstract:OBJECTIVE:To investigate whether the extent of expression of hyaluronan (HA) and epidermal growth factor receptor (EGFR) in squamous cell carcinoma of the mobile tongue can predict the risk of cervical metastasis and survival. STUDY DESIGN:Retrospective histopathologic study. METHODS:Surgical specimens from 64 patien...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章


    authors: Lindell Jonsson E,Nylander K,Hallén L,Laurell G

    更新日期:2017-08-01 00:00:00

  • Investigation of the ototoxicity of gadoteridol (ProHance) and gadodiamide (Omniscan) in mice.

    abstract:CONCLUSION:In the mouse, when a tympanic perforation is present, gadoteridol does not seem to cause ototoxicity. Gadodiamide may cause mild ototoxicity other than toxicity to the outer hair cells of the cochlea. OBJECTIVES:Endolymphatic hydrops have been visualized through intra-tympanic injection of gadolinium-based ...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章


    authors: Nonoyama H,Tanigawa T,Shibata R,Tanaka H,Katahira N,Horibe Y,Takemura K,Murotani K,Ozeki N,Ueda H

    更新日期:2016-11-01 00:00:00

  • Selective resection of the semicircular canals of rabbits with preservation of hearing.

    abstract::The goal of this investigation was to develop a method of surgical removal of the semicircular canals of the rabbit without induction of auditory impairment. Four different surgical techniques were utilized: i) fenestration of the lateral semicircular canal; ii) fibrin glue perfusion of the canal following fenestratio...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章


    authors: Gjuric M,Wigand ME,Hosemann W

    更新日期:1992-11-01 00:00:00

  • Cholesteatoma. A clinical and morphological analysis.

    abstract::A total of 33 consecutively operated aural cholesteatomas were analysed with regard to preoperative findings and correlated with the morphology of the cholesteatoma tissue. Patients were found in all age groups, 9/33 of the patients were operated at an age below 15 years. A persistent ear discharge had occurred in all...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章


    authors: Anniko M,Mendel L

    更新日期:1981-03-01 00:00:00

  • Early timing of low-dose dexamethasone decreases inflammation in a murine model of eosinophilic airway disease.

    abstract:CONCLUSION:A very low dose of dexamethasone (DEX) was as equally as sufficient as a pharmacological dose to decrease eosinophil inflammation in airways and bone marrow. The timing of DEX treatment in relation to allergen challenge was strongly decisive for the outcome of the inflammatory response. OBJECTIVES:We aimed ...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章


    authors: Georén SK,Tcacencu I,Wikström AC,Stierna P

    更新日期:2009-02-01 00:00:00

  • Intraoperative monitoring of facial nerve antidromic potentials during acoustic neuroma surgery.

    abstract::The present paper presents monopolar recording of facial nerve antidromic potentials as an alternative technique to facial electromyography for the continuous monitoring of the facial nerve during acoustic neuroma surgery. The investigation involved 22 patients undergoing acoustic neuroma surgery via a retrosigmoid ap...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章


    authors: Colletti V,Fiorino F,Policante Z,Bruni L

    更新日期:1997-09-01 00:00:00

  • Sonotubometry. An acoustical method for objective measurement of auditory tubal opening.

    abstract::The sound conduction method for measurement of the Eustachian tube opening has been studied and modifications made in the test procedure to increase its easy performance and reliability. By holding the sound source near to the nostril, mounting the microphone into a circumaural ear defender and by feeding the output o...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章


    authors: Virtanen H

    更新日期:1978-07-01 00:00:00

  • Central origin of canine vidian nerve studied by the HRP method.

    abstract::Central origin of the vidian nerve in the dog was investigated using the retrograde tracing technique of horseradish peroxidase (HRP). After HRP was applied to the vidian nerve, labelled neurons were found in the medulla oblongata and the geniculate ganglion but could not be found in the trigeminal ganglion. Labelled ...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章


    authors: Azuma E,Asakura K,Kataura A

    更新日期:1983-07-01 00:00:00

  • The midline electroneurography method for facial palsy reflects total nerve degeneration.

    abstract:CONCLUSION:The midline electroneurography (ENoG) method might reflect total facial nerve degeneration. OBJECTIVE:We compared ENoG values in patients with facial palsy using two different methods, the midline method and five electroneurogram recordings, to reveal whether the ENoG value obtained with the midline method ...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章


    authors: Wada S,Haginomori S,Mori A,Ichihara T,Kanazawa A,Kawata R,Takubo T,Yorifuji S

    更新日期:2013-03-01 00:00:00

  • Evoked potentials from the auditory nerve following sinusoidal electrical stimulation of the cochlea: new possibilities for preoperative testing in cochlear-implant candidates?

    abstract::To predict the possible benefit of a cochlear implant to a patient, the clinician requires a reliable objective method to monitor the presence of surviving fibres in the 8th nerve. The subjective promontory test and the evaluation of electrically evoked brainstem potentials are not adequate. An electrical stimulus art...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章


    authors: Hartmann R,Pfennigdorff T,Klinke R

    更新日期:1994-09-01 00:00:00

  • A simple objective evaluation and grading for facial paralysis outcomes.

    abstract:CONCLUSION:A simple measuring box to determine lip-shift angle and eye-width narrowing offered simultaneous and objective data on outcome dysfunction. The method is as easy as visual approaches. The method is objective and as easy as visual access. It is practical for routine clinical use in any clinic. OBJECTIVES:The...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章


    authors: Saito H

    更新日期:2012-01-01 00:00:00

  • Potential pitfalls and therapeutic implications of pretherapeutic radiologic staging in glottic cancers.

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    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章


    authors: Lim JY,Park IS,Park SW,Kim JW,Kim YM

    更新日期:2011-08-01 00:00:00

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    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章


    authors: Ikeda K,Yokoi H,Saito T,Kawano K,Yao T,Furukawa M

    更新日期:2008-01-01 00:00:00

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    pub_type: 临床试验,杂志文章


    authors: Tsukahara K,Nakamura K,Motohashi R,Sato H,Endo M,Katsube Y,Ueda Y,Suzuki M

    更新日期:2014-11-01 00:00:00

  • Cochlear pathology following exposure to mercury.

    abstract::The sensory and secretory epithelia may become morphologically changed following the exposure to mercury chloride. The earliest and most sever change in the sensory epithelium appeared in the apical part of the cochlea, while the basal coils were only seldom damaged (cytocochleogram studies). Acute intoxication mostly...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章


    authors: Anniko M,Sarkady L

    更新日期:1978-03-01 00:00:00

  • Age-related changes in the expression of NMDA, serotonin, and GAD in the central auditory system of the rat.

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    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章


    authors: Shim HJ,Lee LH,Huh Y,Lee SY,Yeo SG

    更新日期:2012-01-01 00:00:00

  • The anti-inflammatory effect of erythromycin and its derivatives, with special reference to nasal polyposis and chronic sinusitis.

    abstract::Macrolides have been used for decades as an important chemotherapeutic agent in the treatment of infectious diseases. In the last 10 years there has also been increasing interest in the interaction between macrolide antibiotics and the immune system. The aim of this review is to focus on the anti-inflammatory action o...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章,评审


    authors: Cervin A

    更新日期:2001-01-01 00:00:00

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    abstract::In a study on the effects of a frequency-dependent automatic gain control in hearing-aids, two experiments were carried out with hearing-impaired listeners. In the first experiment, the effect of varying the amplitude-frequency response on the speech-reception threshold (SRT) of sentences presented in noise was studie...

    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章


    authors: Van Dijkhuizen JN,Festen JM,Plomp R

    更新日期:1990-01-01 00:00:00

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    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章


    authors: Wang D,Brihaye P,Smitz J,De Waele M,Clement P

    更新日期:1996-05-01 00:00:00

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    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章


    authors: Mohammad Azmi HH,Goh BS,Abdullah A,Umat C

    更新日期:2020-10-01 00:00:00

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    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章


    authors: Gao N,Xu XD,Chi FL,Zeng FG,Fu QJ,Jia XH,Yin YB,Ping LC,Kang HY,Feng HH,Wu YZ,Jiang Y

    更新日期:2016-01-01 00:00:00

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    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章


    authors: Wit HP,Segenhout JM

    更新日期:1988-03-01 00:00:00

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    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章


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    pub_type: 杂志文章,多中心研究,随机对照试验


    authors: Lindblom U,Nilsson P,Gärskog O,Kjellen E,Laurell G,Wahlberg P,Zackrisson B,Levring Jäghagen E

    更新日期:2016-01-01 00:00:00

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    journal_title:Acta oto-laryngologica

    pub_type: 杂志文章


    authors: Gavilán C,Gavilán J,Rashad M,Gavilán M

    更新日期:1988-09-01 00:00:00