Ex Vivo Porcine Organ Perfusion Models as a Suitable Platform for Translational Transplant Research.

abstract：:Dual chamber (DC) peritoneal dialysis (PD) dialysates contain fewer glucose degradation products (GDPs), so potentially reducing advanced glycosylation end products (AGEs), which have been reported to increase inflammation and cardiovascular risk. We wished to determine whether use of DC dialysates resulted in demonst...

journal_title：Artificial organs

authors： Vareesangthip K,Vongsanim S,Fan S,Davenport A

更新日期：2020-07-09 00:00:00

abstract：:The E4T is a totally implantable total artificial heart (TAH) resulting from many years of research work at the Cleveland Clinic Foundation (CCF) and Nimbus, Inc. It consists of four implanted subsystems: the pumping unit, the variable volume device, the transcutaneous transformer, and the internal battery. The pumpin...

journal_title：Artificial organs

authors： Smith WA,Hete BF,Kiraly RJ,Fujimoto LK,Jacobs GB,Ishikawa M,Butler K,Nosé Y

更新日期：1988-10-01 00:00:00

abstract：:Liposome-encapsulated hemoglobin (LEH) was proven to be protective in cerebral ischemia/reperfusion injury. The present study evaluated LEH in a rat model of permanent middle cerebral artery (MCA) occlusion to clarify its effect during ischemia and reperfusion. Five minutes after thread occlusion of the MCA, rats were...

journal_title：Artificial organs

authors： Kawaguchi AT,Kurita D,Furuya H,Yamano M,Ogata Y,Haida M

更新日期：2009-02-01 00:00:00

abstract：:We made miniature modules filled with artificial oxygenator hollow fibers and conducted a simple experiment to study the effect of different membrane structures on the blood. Three types of modules were made: one filled with polyolefin, one filled with polypropylene, and a blank module. The 3 modules were connected th...

journal_title：Artificial organs

authors： Nishida H,Shibuya M,Endo M,Koyanagi H

更新日期：1996-12-01 00:00:00

abstract：:In clinical settings, no method has been established to examine the fatigue of a latissimus dorsi muscle (LDM) preconditioned for cardiomyoplasty. We examined the feasibility of measuring muscle stiffness (tactile stiffness) to evaluate muscle fatigue in situ using our tactile sensor. We stimulated canine LDM with bur...

journal_title：Artificial organs

authors： Inaba H,Miyaji K,Kaneko Y,Ohtsuka T,Ezure M,Tambara K,Takamoto S,Omata S

更新日期：2000-10-01 00:00:00

abstract：:In this study, the hypothesis was tested that a low-resistant, high-compliant oxygenator provides better pulse conductance and less hemolysis than a high-resistant, low-compliant oxygenator during pulsatile cardiopulmonary bypass. Forty adults undergoing coronary artery bypass surgery were randomly divided into two gr...

journal_title：Artificial organs

authors： Simons AP,Wortel P,van Kan RA,van der Veen FH,Weerwind PW,Maessen JG

更新日期：2010-04-01 00:00:00

abstract：:This is a revision of the IDE Application Form, "How to Comply with the Food and Drug Administration's New 'Investigational Device Exemption (IDE)' Regulations, Including an Application Form" originally published in Artificial Organs, Volume 4, Number 4, November 1980. This publication updates the IDE application form...

journal_title：Artificial organs

authors：

更新日期：1982-02-01 00:00:00

abstract：:Cell exclusion is the phenomenon whereby the hematocrit and viscosity of blood decrease in areas of high stress. While this is well known in naturally occurring Poiseuille flow in the human body, it has never previously been shown in Couette flow, which occurs in implantable devices including blood pumps. The high-she...

journal_title：Artificial organs

authors： Leslie LJ,Marshall LJ,Devitt A,Hilton A,Tansley GD

更新日期：2013-03-01 00:00:00

abstract：:Pyridoxalated-hemoglobin-polyoxyethylene conjugate (PHP), which is made from out-dated human red blood cells by two major chemical modifications, namely pyridoxalation and conjugation with polyoxyethylene (POE), is currently under development as a physiological oxygen carrier. This study assessed the effects of PHP-88...

journal_title：Artificial organs

authors： Takahashi T,Iwasaki K,Malchesky PS,Harasaki H,Matsushita M,Nosé Y,Rolin H 3rd,Hall PM

更新日期：1993-03-01 00:00:00

abstract：:Midsize molecule retention is related with renal-failure-associated mortality. Here, the authors describe a new dialysis modality, pulse push/pull hemodialysis (PPPHD), which increases convective clearance. Blood and dialysate are circulated by a pulsatile pump, but with pulsatile flow patterns that are 180 degrees ou...

journal_title：Artificial organs

authors： Lee K,Lee SR,Mun CH,Min BG

更新日期：2008-05-01 00:00:00

abstract：:Bubble blood oxygenators equipped with baffles of various types in the oxygenating column were studied. The rate of hemolysis, the volumetric coefficient for oxygen absorption into blood, and the fractional gas holdup were found to be affected mainly by the superficial gas velocity. When compared with the conventional...

journal_title：Artificial organs

authors： Ohshima N,Yoshido F

更新日期：1979-05-01 00:00:00

abstract：:The objective of this study is to compare the myocardium protective effect of Bretschneider's histidine-tryptophan-ketoglutarate (HTK) solution versus Modified St. Thomas' (STH) solution in pediatric cardiac surgery of Tetralogy of Fallot (TOF). Seventy-seven pediatric patients of TOF who received the total surgical r...

journal_title：Artificial organs

authors： Wang ZH,An Y,Du MC,Qin TJ,Liu YB,Xu HZ,Yang LQ

更新日期：2017-05-01 00:00:00

abstract：:We compared in vitro rates of hemolysis for a recently developed centrifugal pump with a conventional roller pump (10-10-00; Stöckert, Munich, Germany). Flow rates of 0.3 L/min and 1 L/min and a pressure of 200 mm Hg were chosen to simulate conditions during neonatal extracorporeal membrane oxygenation (ECMO). There w...

journal_title：Artificial organs

authors： Moon YS,Ohtsubo S,Gomez MR,Moon JK,Nosé Y

更新日期：1996-06-01 00:00:00

abstract：:This study was planned to investigate whether part of the energy produced by cardiac contraction to propel blood toward the systemic circulation can be used to increase the coronary flow in systole. Ten devices (I-X) designed to divert laterally part of a flow column (without substantially increasing resistance to flo...

journal_title：Artificial organs

authors： Moulopoulos S,Stamatelopoulos S,Boufas D,Yannopoulos C,Marousis G,Kouvaras G

更新日期：1979-11-01 00:00:00

abstract：:Total hip arthroplasty (THA) can be achieved by using a cemented or noncemented prosthesis. Besides patient's age, weight, and other clinical signs, the evaluation of the quality of the bones is a crucial parameter on which orthopedic surgeons base the choice between cemented and noncemented THA. Although bone density...

journal_title：Artificial organs

authors： Gargiulo P,Pétursson T,Magnússon B,Bifulco P,Cesarelli M,Izzo GM,Magnúsdóttir G,Halldórsson G,Ludvigsdóttir GK,Tribel J,Jónsson H Jr

更新日期：2013-06-01 00:00:00

abstract：:We aim to evaluate clinical outcomes of emergent extracorporeal membrane oxygenation (ECMO) implantation in newborns with life-threatening meconium aspiration syndrome (MAS) in peripheral hospitals with Hub and Spoke (HandS) setting. We retrospectively reviewed all neonates presenting with MAS, with no other comorbidi...

journal_title：Artificial organs

authors： Fichera D,Zanella F,Fabozzo A,Doglioni N,Trevisanuto D,Lolli E,Vida V,Ceccherini E,Ebraico A,Stellin G,Padalino M

更新日期：2019-01-01 00:00:00

abstract：PURPOSE:We were led to the premise that with retrograde oxygenated blood perfusion, it would be possible to perform operations on the beating heart. METHODS:The experiment consisted of two stages: procedure 1 and 2. In procedure 1, six pigs were used. Retrograde perfusion flow was controlled to be in the range of 5.0-...

journal_title：Artificial organs

authors： Tsukioka T,Tomita S,Watanabe G,Takemura H

更新日期：2004-03-01 00:00:00

abstract：:The objective of this study was to evaluate an alternative neonatal extracorporeal life support (ECLS) circuit with a RotaFlow centrifugal pump and Better-Bladder (BB) for hemodynamic performance and gaseous microemboli (GME) capture in a simulated neonatal ECLS system. The circuit consisted of a Maquet RotaFlow centr...

journal_title：Artificial organs

authors： Spencer SB,Wang S,Woitas K,Glass K,Kunselman AR,Ündar A

更新日期：2017-01-01 00:00:00

abstract：:Solute clearance during high-flux hemodialysis is determined by the combined effects of solute convection and diffusion in the membrane, blood, and dialysate. Previous studies have focused almost entirely on the membrane transport phenomena, largely ignoring the potential contribution from bulk mass transport across t...

journal_title：Artificial organs

authors： Zydney AL

更新日期：1993-11-01 00:00:00

abstract：:Transcatheter aortic valve implantation (TAVI) has gained considerable acceptance in the past decade due to its lower risks than conventional open-heart surgery. However, the deformation and delamination of the leaflets during the crimping procedure have raised questions about the durability and long-term serviceabili...

journal_title：Artificial organs

authors： Mao J,Rassoli A,Tong Y,Rouse EN,Le-Bel G,How D,Germain L,Fatouraee N,Zhang Z,Reed RR,Guidoin R

更新日期：2019-10-01 00:00:00

abstract：:In patients undergoing exchange-transfusion with hemoglobin (Hb)-based oxygen (O₂) carriers (HBOC), native Hb coexists with newly transfused Hb. The two Hb types share the same arterial and venous PO₂, but their affinities for O₂ vary. A simple spreadsheet model is described aiming at evaluating the contribution of ea...

journal_title：Artificial organs

authors： Samaja M,Terraneo L

更新日期：2012-02-01 00:00:00

abstract：:An apparatus has been contructed to regulate ultrafiltration accurately during dialysis. The principle of the apparatus is that, per unit of time, exactly the same amount of dialysate is introduced into the dialyzer as is discharged from it. The apparatus consists of two isovolumetric pumps connected in line. The four...

journal_title：Artificial organs

authors： Flendrig JG,Carpay WM,Dekkers WT

更新日期：1978-05-01 00:00:00

abstract：:Vecuronium is a curaric agent, largely used in anesthesia. Indications as to its employ in uremic patients appear to be debated because of partial renal elimination of the drug. A 52-year-old hemodialyzed woman required transplantectomy for rejection. At awakeness after general anesthesia (induced with fentanyl, propo...

journal_title：Artificial organs

authors： Rollino C,Visetti E,Borsa S,Pignataro A,Pozzato M,Vallero A,Quarello F

更新日期：2000-05-01 00:00:00

abstract：:Hemodialysis vascular access (VA) stenosis remains a frequent complication. However, early detection is challenging and costly. The aim of this in vitro study was to assess a new detection method based on pulse pressure analysis at the hemodialysis needle. A silicon model of a radiocephalic arteriovenous fistula was b...

journal_title：Artificial organs

authors： Van Canneyt K,Planken RN,Eloot S,Segers P,Verdonck P

更新日期：2010-02-01 00:00:00

abstract：:Central vascular catheters are used to access the central vascular system in both acute and chronic uremic patients undergoing hemodialysis. Among different approaches, the internal jugular vein seems to have less adverse effects. We describe our long-term experience with a two-catheter system. Percutaneous jugular ve...

journal_title：Artificial organs

authors： Tesio F,De Baz H,Panarello G,Calianno G,Quaia P,Raimondi A,Schinella D

更新日期：1994-04-01 00:00:00

abstract：:Albumin-coated Amberlite XAD-7 has been previously shown to be blood compatible in in vitro hemoperfusion experiments whith human blood. In this study, the preliminary results are reported on single hemoperfusions with albumin-coated XAD-7 resin in four patients with acute liver failure. The mean platelet count was 11...

journal_title：Artificial organs

authors： Hughes R,Ton HY,Langley P,Davies M,Hanid MA,Mellon P,Silk DB,Williams R

更新日期：1979-02-01 00:00:00

abstract：:Many patients all over the world suffer from acute wounds caused by traumas or burns. In most crucial cases, skin regeneration cannot be promoted spontaneously, and skin grafts are applied as the main treatment. However, this therapy has some drawbacks which motivate researchers to develop wound dressings. In this stu...

journal_title：Artificial organs

authors： Mohseni M,Shamloo A,Aghababaei Z,Vossoughi M,Moravvej H

更新日期：2016-08-01 00:00:00

abstract：:The use of and demand for functional electrical stimulation (FES) systems and conventional orthoses in the spinal cord lesioned population was assessed. The assessment was conducted by a postal survey of the members of the spinal injury associations in the U.K. Out of all the respondents, only 2% had used an FES syste...

journal_title：Artificial organs

authors： Maxwell DJ,Granat MH,Baardman G,Hermens HJ

更新日期：1999-05-01 00:00:00

abstract：:This article reports preliminary results of pilot studies of a new implantable two channel drop foot stimulator. The stimulator consists of an externally worn transmitter inductively coupled to an implanted receiver unit located in the lower leg, lateral and distal to the knee. The receiver is connected to electrodes ...

journal_title：Artificial organs

authors： Kenney L,Bultstra G,Buschman R,Taylor P,Mann G,Hermens H,Holsheimer J,Nene A,Tenniglo M,van der Aa H,Hobby J

更新日期：2002-03-01 00:00:00

abstract：:Characteristics of morphology, cardiac function, and cardiac reserve at late state were evaluated at rest, by changing the pacing rates, and after exercise in patients with ventricular pacemakers for isolated congenital complete atrioventricular block. Heart size was reduced statistically after pacemaker implantation,...

journal_title：Artificial organs

authors： Nawa S,Kioka Y,Shimizu A,Tsuji H,Miyachi Y,Ebara K,Kino K,Shigenobu M,Murakami T,Senoo Y

更新日期：1987-06-01 00:00:00