Appearance of IgG and IgA antibodies in human bile after tetanus toxoid immunization.

abstract：:Systemic capillary leak syndrome (SCLS) is a rare disease characterized by episodes of collapse due to rapid transfer of considerable volumes of plasma from the intravascular to the extravascular compartment. The pathogenesis of this disease is unknown. The diagnosis is made largely on clinical grounds, and investigat...

journal_title：Clinical and experimental immunology

authors： Zhang W,Ewan PW,Lachmann PJ

更新日期：1993-09-01 00:00:00

abstract：:EAU is a model of ocular inflammatory disease. EAU resembles another T cell-mediated autoimmune disease--experimental allergic encephalomyelitis--since both have increased expression of MHC class II molecules in the target tissue, can be adoptively transferred by activated CD4+ T cells and are inhibited by cyclosporin...

journal_title：Clinical and experimental immunology

authors： Calder VL,Lightman SL

更新日期：1992-08-01 00:00:00

abstract：:Natural autoantibodies (NaAb) and IgG antibodies to tetanus toxoid (TT) were analysed in the sera of 38 children with active visceral leishmaniasis (VL) previously vaccinated with TT and in 30 healthy controls matched for sex and age. Patients exhibited high levels of NaAb to a panel of self antigens (tubulin, myosin,...

journal_title：Clinical and experimental immunology

authors： Louzir H,Belal-Kacemi L,Sassi A,Laouini D,Ben Ismail R,Dellagi K

更新日期：1994-03-01 00:00:00

abstract：:IgG, IgM and hepatitis B surface antigen (HBsAg) containing immune complexes (IC) were detected by the Clq and conglutinin solid phase assays in both HBsAg+ and HBsAg- groups of patients with primary hepatocellular carcinoma (HCC). No differences were observed between the two patient groups either in the levels of ant...

journal_title：Clinical and experimental immunology

authors： Brown SE,Howard CR,Steward MW,Ajdukiewicz AB,Whittle HC

更新日期：1984-02-01 00:00:00

abstract：:Ten patients with chronic lymphatic leukaemia (CLL) were injected with the antigen phichi174 intravenously on two occasions to test their capacity for antibody production. Nine out of ten patients failed to develop a primary response, and five out of ten failed to develop a secondary response. Only one out of the ten ...

journal_title：Clinical and experimental immunology

authors： Hamblin TJ,Jones JV,Peacock DB

更新日期：1975-07-01 00:00:00

abstract：:Mixtures of serum of Freund's complete adjuvant (FCA) immunized guinea-pigs and tuberculin PPD consistently inhibited the in vitro migration of peritoneal exudate cells (PEC) of normal guinea-pigs. It is shown that this inhibitory effect is due to a soluble complex between an IgG2 antibody and PPD. By separation of PP...

journal_title：Clinical and experimental immunology

authors： Kotkes P,Pick E

更新日期：1975-01-01 00:00:00

abstract：:The frequency and specificity of antibodies to native and denatured collagens were evaluated in systemic sclerosis (SSc) and in primary Raynaud's phenomenon (PRP) by direct and competitive ELISA. Antibodies reactive with denatured collagen type I (CI) were found in 43% of the SSc sera, and anti-CIV and anti-CV in 31%....

journal_title：Clinical and experimental immunology

authors： Riente L,Marchini B,Dolcher MP,Puccetti A,Bombardieri S,Migliorini P

更新日期：1995-11-01 00:00:00

abstract：:Sarcoidosis is a systemic, inflammatory disorder, which in a proportion of patients runs a chronic progressive course despite immunosuppressive treatment. Therapeutic granulocyte and monocyte apheresis (GMA) has been shown to be an effective treatment option for other systemic inflammatory disorders, but has not yet b...

journal_title：Clinical and experimental immunology

authors： Olsen HH,Muratov V,Cederlund K,Lundahl J,Eklund A,Grunewald J

更新日期：2014-09-01 00:00:00

abstract：:The repeated administration of a monoclonal anti-Sm antibody (KSml) resulted in a significant prolongation of life in MRL-lpr/lpr lupus mice with a 50% mortality of 36 weeks compared with 18-24 weeks in the control groups. Control animals injected with APC11 (a myeloma protein of the same isotype) lived no longer than...

journal_title：Clinical and experimental immunology

authors： Brennan FM,Williams DG,Bovill D,Stocks MR,Maini RN

更新日期：1986-07-01 00:00:00

abstract：:Spontaneous sperm agglutination was observed in the ejaculate of a 39-year-old male (patient Z). Using an enzyme-linked immunosorbent assay (ELISA) with spermatozoa fixed to wells of a microtitre plate it was determined that IgA was associated with patient Z's spermatozoa but not with a pooled sample of spermatozoa fr...

journal_title：Clinical and experimental immunology

authors： Witkin SS,Zelikovsky G,Good RA,Day NK

更新日期：1981-05-01 00:00:00

abstract：:Glucocorticoid hormones (GCH) regulate, through the apoptotic process, the negative selection of immature T cells in the thymus. Because apoptosis seems to occur also in the maintenance of peripheral tolerance, we have investigated whether GCH may induce apoptosis in human mature lymphocytes. Peripheral blood lymphocy...

journal_title：Clinical and experimental immunology

authors： Lanza L,Scudeletti M,Puppo F,Bosco O,Peirano L,Filaci G,Fecarotta E,Vidali G,Indiveri F

更新日期：1996-03-01 00:00:00

abstract：:People receiving therapy with either 8-methoxypsoralen plus long wavelength ultraviolet radiation (PUVA) or medium wavelength ultraviolet radiation (UVB) have been studied to see whether their unresponsiveness to the contact sensitizer dinitrochlorobenzene (DNCB) is a form of immunological tolerance. It was confirmed ...

journal_title：Clinical and experimental immunology

authors： Friedmann PS,White SI,Parker S,Moss C,Matthews JN

更新日期：1989-04-01 00:00:00

abstract：:Purified proteins (Pa-1 and Pa-2) from pokeweed have been compared with commercial pokeweed mitogen (PWM-G) and other mitogens in their ability to stimulate human lymphocytes. With cultures of T and B cells separated from tonsil lymphocytes, thymidine uptake, blast transformation and immunoglobulin (Ig) synthesis have...

journal_title：Clinical and experimental immunology

authors： Janossy G,Gomez De La Concha E,Waxdal MJ,Platts-Mills T

更新日期：1976-10-01 00:00:00

abstract：:CFA is an inflammatory condition of the lungs resulting in scarring, pulmonary failure and death. The etiology of the disease is unknown, but the pathogenesis is believed to involve a persistent immunological reaction to unidentified antigen in the lung resulting in tissue damage. Recent advances in our understanding ...

journal_title：Clinical and experimental immunology

authors： Wallace WA,Ramage EA,Lamb D,Howie SE

更新日期：1995-09-01 00:00:00

abstract：:There are estimated to be approximately 1500 people in the United Kingdom with C1 inhibitor (C1INH) deficiency. At BartsHealth National Health Service (NHS) Trust we manage 133 patients with this condition and we believe that this represents one of the largest cohorts in the United Kingdom. C1INH deficiency may be her...

journal_title：Clinical and experimental immunology

authors： Manson AL,Price A,Dempster J,Clinton-Tarestad P,Greening C,Enti R,Hill S,Grigoriadou S,Buckland MS,Longhurst HJ

更新日期：2013-07-01 00:00:00

abstract：:Costimulation of T lymphocytes by the leucocyte surface molecules CD80 and CD86 expressed on antigen-presenting cells (APC) is required for the development of T cell responses. The CD28 and CTLA-4 molecules on T cells serve as receptors for the CD80 and CD86 costimulatory antigens. We have examined the frequency of ex...

journal_title：Clinical and experimental immunology

authors： Melichar B,Nash MA,Lenzi R,Platsoucas CD,Freedman RS

更新日期：2000-01-01 00:00:00

abstract：:CD30 is a surface molecule which can be expressed by normal B and T lymphocytes. Our study focused on the CD30 expression and release compared with IL-4 expression as well as CD23-alpha/beta in peripheral blood mononuclear cells (PBMC) from atopic subjects and controls. Data showed a lack of CD30 mRNA expression in th...

journal_title：Clinical and experimental immunology

authors： Esnault S,Benbernou N,Lavaud F,Guenounou M

更新日期：1996-10-01 00:00:00

abstract：:The family of Toll-like receptors (TLRs) initiates innate immune responses, and Toll-like receptor 4 (TLR4) was considered to be an important player in the initiation and progression of atherosclerotic disease. The aim of the study was to investigate the expression of TLR4 on peripheral-blood mononuclear cells (PBMCs)...

journal_title：Clinical and experimental immunology

authors： Geng HL,Lu HQ,Zhang LZ,Zhang H,Zhou L,Wang H,Zhong RQ

更新日期：2006-02-01 00:00:00

abstract：:An association between mannan-binding lectin (MBL) status and severity of lung function impairment in cystic fibrosis (CF) has been found in several studies, but not in others. To explore the possible basis for discrepancies in the literature, we related both MBL and L-ficolin concentrations to lung function and exami...

journal_title：Clinical and experimental immunology

authors： Muhlebach MS,MacDonald SL,Button B,Hubbard JJ,Turner ML,Boucher RC,Kilpatrick DC

更新日期：2006-08-01 00:00:00

abstract：:Isoelectric focusing of serial bleeds from patients with Hashimoto's thyroiditis was carried out and thyroglobulin (Tg) autoantibodies visualized using 125I-labelled Tg followed by autoradiography. Although the spectrotype of these antibodies was polyclonal and varied from patient to patient, each individual's spectro...

journal_title：Clinical and experimental immunology

authors： Delves PJ,Roitt IM

更新日期：1988-03-01 00:00:00

abstract：:We have investigated the expression of chemokines and their receptors in leprosy skin lesions using immunohistochemistry. Skin biopsies from 25 leprosy patients across the leprosy spectrum, 11 patients undergoing type I reversal reactions and four normal donors were immunostained by ABC peroxidase method using antibod...

journal_title：Clinical and experimental immunology

authors： Kirkaldy AA,Musonda AC,Khanolkhar-Young S,Suneetha S,Lockwood DN

更新日期：2003-12-01 00:00:00

abstract：:The biological role of T cell receptor (TCR) gamma delta bearing cells is currently not fully understood. Recently, a monoclonal antibody (TCR delta 1) reacting against the whole molecule became available which facilitates the direct analysis of TCR-gamma delta+ cells. We studied 11 children with atopic dermatitis, 20...

journal_title：Clinical and experimental immunology

authors： Schauer U,Dippel E,Gieler U,Bräuer J,Jung T,Heymanns J,Rieger CH

更新日期：1991-12-01 00:00:00

abstract：:Functional impairments of polymorphonuclear granulocytes (PMN) are believed to contribute to hampered inflammation and host defence in alcoholics. We studied effects of i.v. ethanol administration on PMN responses in rabbits during induction of a knee-joint synovitis. The synovitis conferred systemic effects, since ch...

journal_title：Clinical and experimental immunology

authors： Nilsson E,Thomsen P,Ericson L,Palmblad J

更新日期：1995-10-01 00:00:00

abstract：:Using in situ hybridization, we analysed the immunoglobulin repertoire expressed by the B cells present in myasthenia gravis thymuses from four patients. B cells, mostly in activated state, were clustered in germinal centres, in which multiple isotypes were identified. A majority of cells expressed IgG as compared wit...

journal_title：Clinical and experimental immunology

authors： Guigou V,Emilie D,Berrih-Aknin S,Fumoux F,Fougereau M,Schiff C

更新日期：1991-02-01 00:00:00

abstract：:It has been demonstrated immunohistologically using cryostat sections that the lectins PHA and Con A bind to human placentae. Both lectins stain trophoblastic basement membrane (TBM), perivascular tissue and stroma. No staining of trophoblasts was observed. It has been shown by blocking experiments that the lectin bin...

journal_title：Clinical and experimental immunology

authors： Johnson PM,Faulk WP

更新日期：1976-06-01 00:00:00

abstract：:Both CC- and CXC-chemokines are known to be potent leucocyte activators and chemoattractants and play important roles in inflammatory responses. However, chemokine response to bacillus Calmette-Guérin (BCG) infection remains incompletely defined. In this study, we investigated human CC- [macrophage-derived chemokine (...

journal_title：Clinical and experimental immunology

authors： Luo Y,Chen X,O'Donnell MA

更新日期：2007-02-01 00:00:00

abstract：:Our study aimed to determine the functional activity of different osteoclast progenitor (OCP) subpopulations and signals important for their migration to bone lesions, causing local and systemic bone resorption during the course of collagen-induced arthritis in C57BL/6 mice. Arthritis was induced with chicken type II ...

journal_title：Clinical and experimental immunology

authors： Ikić Matijašević M,Flegar D,Kovačić N,Katavić V,Kelava T,Šućur A,Ivčević S,Cvija H,Lazić Mosler E,Kalajzić I,Marušić A,Grčević D

更新日期：2016-12-01 00:00:00

abstract：:In order to evaluate the impact of induction and increase target antigen expression on immunotoxin potency, we measured the potentiating effect of recombinant immune interferon-gamma (rIFN-gamma) on the cytotoxicity of an anti HLA-DR ricin A-chain immunotoxin (2G5 RTA-IT) on the myeloid cell line ML-3. After 48 h of i...

journal_title：Clinical and experimental immunology

authors： Chiron M,Jaffrezou JP,Carayon P,Bordier C,Roubinet F,Xavier C,Brandely M,Laurent G

更新日期：1990-11-01 00:00:00

abstract：:The allergenic properties of the proteins of two lyophilized fractions of fresh natural rubber latex obtained by ultracentrifugation, the C serum and the sedimented bottom or lutoid fraction, have been compared with those of the serum proteins of two samples of high ammonia latex (HAL) [A]HALS obtained from HAL stored...

journal_title：Clinical and experimental immunology

authors： Kekwick R,Bhambri S,Chabane MH,Autegarden JE,Levy DA,Leynadier F

更新日期：1996-05-01 00:00:00

abstract：:The predominance of Th2 cytokine-secreting pattern in allergic asthma has been known as a cause and an accelerating factor, and Th1 suppresses these allergic phenomena, but the role of Th0 clones is obscure. Because Th1/Th2 differentiation has been determined by cytokine environment, we investigated how mite-specific ...

journal_title：Clinical and experimental immunology

authors： Yamashita N,Takeno M,Kaneko S,Mizushima Y,Sakane T

更新日期：1997-08-01 00:00:00