In pursuit of excellence: an integrated care pathway for C1 inhibitor deficiency.

Abstract:

:There are estimated to be approximately 1500 people in the United Kingdom with C1 inhibitor (C1INH) deficiency. At BartsHealth National Health Service (NHS) Trust we manage 133 patients with this condition and we believe that this represents one of the largest cohorts in the United Kingdom. C1INH deficiency may be hereditary or acquired. It is characterized by unpredictable episodic swellings, which may affect any part of the body, but are potentially fatal if they involve the larynx and cause significant morbidity if they involve the viscera. The last few years have seen a revolution in the treatment options that are available for C1 inhibitor deficiency. However, this occurs at a time when there are increased spending restraints in the NHS and the commissioning structure is being overhauled. Integrated care pathways (ICP) are a tool for disseminating best practice, for facilitating clinical audit, enabling multi-disciplinary working and for reducing health-care costs. Here we present an ICP for managing C1 inhibitor deficiency.

journal_name

Clin Exp Immunol

authors

Manson AL,Price A,Dempster J,Clinton-Tarestad P,Greening C,Enti R,Hill S,Grigoriadou S,Buckland MS,Longhurst HJ

doi

10.1111/cei.12083

subject

Has Abstract

pub_date

2013-07-01 00:00:00

pages

1-7

issue

1

eissn

0009-9104

issn

1365-2249

journal_volume

173

pub_type

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