Abstract：
:The meaning we derive from our experiences is not a simple static extraction of the elements but is largely based on the order in which those elements occur. Models propose that sequence encoding is supported by interactions between high- and low-frequency oscillations, such that elements within an experience are represented by neural cell assemblies firing at higher frequencies (gamma) and sequential order is encoded by the specific timing of firing with respect to a lower frequency oscillation (theta). During episodic sequence memory formation in humans, we provide evidence that items in different sequence positions exhibit greater gamma power along distinct phases of a theta oscillation. Furthermore, this segregation is related to successful temporal order memory. Our results provide compelling evidence that memory for order, a core component of an episodic memory, capitalizes on the ubiquitous physiological mechanism of theta-gamma phase-amplitude coupling.
journal_name
Nat Neuroscijournal_title
Nature neuroscienceauthors
Heusser AC,Poeppel D,Ezzyat Y,Davachi Ldoi
10.1038/nn.4374subject
Has Abstractpub_date
2016-10-01 00:00:00pages
1374-80issue
10eissn
1097-6256issn
1546-1726pii
nn.4374journal_volume
19pub_type
杂志文章abstract：:Spillover of glutamate under physiological conditions has only been established as an adjunct to conventional synaptic transmission. Here we describe a pure spillover connection between the climbing fiber and molecular layer interneurons in the rat cerebellar cortex. We show that, instead of acting via conventional sy...
journal_title：Nature neuroscience
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abstract：:An afterimage looks larger when one fixates on a distant than on a closer surface. We show that the retinotopic activity in the primary visual cortex (V1) associated with viewing an afterimage is modulated by perceived size, even when the size of the retinal image remains constant. This suggests that V1 has an importa...
journal_title：Nature neuroscience
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abstract：:Social behaviors recruit multiple cognitive operations that require interactions between cortical and subcortical brain regions. Interareal synchrony may facilitate such interactions between cortical and subcortical neural populations. However, it remains unknown how neurons from different nodes in the social brain ne...
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journal_title：Nature neuroscience
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abstract：:In the version of this article initially published, the annotation accompanying ref. 47 ended with "though the modulation of microglia." The first word of this phrase should have been "through." The error has been corrected in the HTML and PDF versions of the article. ...
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pub_type： 已发布勘误
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pub_type： 杂志文章
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journal_title：Nature neuroscience
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更新日期：2013-11-01 00:00:00
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更新日期：2013-08-01 00:00:00
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更新日期：2005-02-01 00:00:00
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更新日期：1999-05-01 00:00:00
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pub_type： 杂志文章
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更新日期：2013-03-01 00:00:00
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journal_title：Nature neuroscience
pub_type： 杂志文章
doi：10.1038/nn2020
更新日期：2008-01-01 00:00:00
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更新日期：2018-05-01 00:00:00
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pub_type： 杂志文章,评审
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更新日期：2014-10-01 00:00:00
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