Visual-spatial processing and working-memory load as a function of negative and positive psychotic-like experiences.

Abstract:

INTRODUCTION:Patients with schizophrenia show impairments in working-memory and visual-spatial processing, but little is known about the dynamic interplay between the two. To provide insight into this important question, we examined the effect of positive and negative symptom expressions in healthy adults on perceptual processing while concurrently performing a working-memory task that requires the allocations of various degrees of cognitive resources. METHODS:The effect of positive and negative symptom expressions in healthy adults (N = 91) on perceptual processing was examined in a dual-task paradigm of visual-spatial working memory (VSWM) under three conditions of cognitive load: a baseline condition (with no concurrent working-memory demand), a low VSWM load condition, and a high VSWM load condition. RESULTS:Participants overall performed more efficiently (i.e., faster) with increasing cognitive load. This facilitation in performance was unrelated to symptom expressions. However, participants with high-negative, low-positive symptom expressions were less accurate in the low VSWM condition compared to the baseline and the high VSWM load conditions. CONCLUSIONS:Attenuated, subclinical expressions of psychosis affect cognitive performance that is impaired in schizophrenia. The "resource limitations hypothesis" may explain the performance of the participants with high-negative symptom expressions. The dual-task of visual-spatial processing and working memory may be beneficial to assessing the cognitive phenotype of individuals with high risk for schizophrenia spectrum disorders.

journal_name

Cogn Neuropsychiatry

authors

Abu-Akel A,Reniers RL,Wood SJ

doi

10.1080/13546805.2016.1206873

subject

Has Abstract

pub_date

2016-09-01 00:00:00

pages

402-411

issue

5

eissn

1354-6805

issn

1464-0619

journal_volume

21

pub_type

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