Cognitive neuropsychiatric analysis of an additional large Capgras delusion case series.

Abstract:

INTRODUCTION:Although important to cognitive neuropsychiatry and theories of delusions, Capgras delusion has largely been reported in single case studies. Bell et al. [2017. Uncovering Capgras delusion using a large scale medical records database. British Journal of Psychiatry Open, 3(4), 179-185] previously deployed computational and clinical case identification on a large-scale medical records database to report a case series of 84 individuals with Capgras delusion. We replicated this approach on a new database from a different mental health service provider while additionally examining instances of violence, given previous claims that Capgras is a forensic risk. METHODS:We identified 34 additional cases of Capgras. Delusion phenomenology, clinical characteristics, and presence of lesions detected by neuroimaging were extracted. RESULTS:Although most cases involved misidentification of family members or partners, a notable minority (20.6%) included the misidentification of others. Capgras typically did not present as a monothematic delusion. Few cases had identifiable lesions with no evidence of right-hemisphere bias. There was no evidence of physical violence associated with Capgras. CONCLUSIONS:Findings closely replicate Bell et al. (2017). The majority of Capgras delusion phenomenology conforms to the "dual route" model although a significant minority of cases cannot be explained by this framework.

journal_name

Cogn Neuropsychiatry

authors

Currell EA,Werbeloff N,Hayes JF,Bell V

doi

10.1080/13546805.2019.1584098

subject

Has Abstract

pub_date

2019-03-01 00:00:00

pages

123-134

issue

2

eissn

1354-6805

issn

1464-0619

journal_volume

24

pub_type

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