Abstract:
:Although schizophrenic patients, as a group, show deficits on measures of explicit learning, it is unclear whether they also have deficits on measures of implicit learning. The current study assessed procedural learning in a sample of 48 chronic schizophrenic inpatients and 23 normal controls using the serial reaction time test (SRT). In addition, we examined the clinical correlates of procedural learning. The SRT yields indices of total motor learning and two subcomponents: reaction time learning, and sequence learning. Although patients performed comparably to normal controls on total motor learning, they showed significantly less sequence learning (P <.03) than controls. Reaction time learning did not differ between the two groups. None of the symptom or clinical variables was correlated with the indices of learning. Chronic schizophrenic inpatients showed normal levels of procedural learning on the SRT. However, their learning was qualitatively different than that of controls (i.e. patients showed deficits in sequence learning, but not reaction time learning). Reduced sequence learning could reflect dysfunctional cortico-cerebellar circuits.
journal_name
Cogn Neuropsychiatryjournal_title
Cognitive neuropsychiatryauthors
Green MF,Kern RS,Williams O,McGurk S,Kee Kdoi
10.1080/135468097396360subject
Has Abstractpub_date
1997-05-01 00:00:00pages
123-34issue
2eissn
1354-6805issn
1464-0619journal_volume
2pub_type
杂志文章abstract::The thalamus has been described as a "relay station" for sensory information from most sensory modalities projecting to cortical areas. Therefore injury to the thalamus may result in multimodal sensory and motor deficits. In the present study, a 61-year-old woman suffered a right thalamic cerebral vascular accident (C...
journal_title:Cognitive neuropsychiatry
pub_type: 杂志文章
doi:10.1080/13546800701319094
更新日期:2007-09-01 00:00:00
abstract:INTRODUCTION:It has been suggested that the positive symptoms of acute schizophrenia are a consequence of a disruption of the process that produces latent inhibition (slower acquisition of conditioned responding after preexposure to the conditioned stimulus) and that this effect can be modelled by pro- and antipsychoti...
journal_title:Cognitive neuropsychiatry
pub_type: 杂志文章,评审
doi:10.1080/13546805.2012.667202
更新日期:2012-11-01 00:00:00
abstract:INTRODUCTION:We report a novel delusion, primarily persecutory in form, in which the patient believes that he is being filmed, and that the films are being broadcast for the entertainment of others. METHODS:We describe a series of patients who presented with a delusional system according to which they were the subject...
journal_title:Cognitive neuropsychiatry
pub_type: 杂志文章
doi:10.1080/13546805.2012.666113
更新日期:2012-11-01 00:00:00
abstract:INTRODUCTION:Theory-of-mind (ToM) refers to the ability to understand and predict the behaviour of others based on their mental states. Research from brain imaging and lesion studies indicate that the frontal lobes are both involved and necessary to understand mental states. METHODS:A total of 13 people with Parkinson...
journal_title:Cognitive neuropsychiatry
pub_type: 杂志文章
doi:10.1080/13546800244000292
更新日期:2003-08-01 00:00:00
abstract::The psychopathological basis of delusions in schizophrenia is poorly understood. The most enduring of several early theories has suggested a causal link with formal thought disorder, whereas recent approaches have proposed relationships with a variety of cognitive abnormalities. The correlations of delusions with othe...
journal_title:Cognitive neuropsychiatry
pub_type: 杂志文章
doi:10.1080/135468096396451
更新日期:1996-11-01 00:00:00
abstract:INTRODUCTION:Individuals with schizophrenia, particularly those with passivity symptoms, often feel that their actions and thoughts are controlled by an external agent. Recent evidence has elucidated the role of body representations in the aetiology of passivity symptoms, yet one representation - body structural descri...
journal_title:Cognitive neuropsychiatry
pub_type: 杂志文章
doi:10.1080/13546805.2016.1231111
更新日期:2016-07-01 00:00:00
abstract::INTRODUCTION. Ample evidence already shows that theory of mind (ToM) is impaired in people with schizophrenia. Our aim was to critically review this literature. METHOD. We completed a selected review of the research literature on ToM in schizophrenia. RESULTS. Gaps in ToM research were identified. A specific relations...
journal_title:Cognitive neuropsychiatry
pub_type: 杂志文章,评审
doi:10.1080/13546805.2011.561576
更新日期:2011-11-01 00:00:00
abstract:INTRODUCTION:Although important to cognitive neuropsychiatry and theories of delusions, Capgras delusion has largely been reported in single case studies. Bell et al. [2017. Uncovering Capgras delusion using a large scale medical records database. British Journal of Psychiatry Open, 3(4), 179-185] previously deployed c...
journal_title:Cognitive neuropsychiatry
pub_type: 杂志文章
doi:10.1080/13546805.2019.1584098
更新日期:2019-03-01 00:00:00
abstract:BACKGROUND:Substance abuse is highly prevalent in schizophrenia and it has been associated with negative consequences on the course of the pathology. Regarding cognition, the prevailing literature has produced mixed results. Some groups have reported greater cognitive impairments in dual diagnosis schizophrenia, while ...
journal_title:Cognitive neuropsychiatry
pub_type: 杂志文章
doi:10.1080/13546800802264330
更新日期:2008-07-01 00:00:00
abstract:INTRODUCTION:Memory for public and autobiographical events was investigated in people diagnosed with depression, schizophrenia, and a group of healthy controls. The aim was to determine whether the overgeneral memory effect emerged in clinical conditions other than depression and in memory domains other than autobiogra...
journal_title:Cognitive neuropsychiatry
pub_type: 杂志文章
doi:10.1080/13546800601066142
更新日期:2007-07-01 00:00:00
abstract:INTRODUCTION:It is assumed that people spontaneously evaluate any incoming stimulus as pleasant or unpleasant. The evaluative response appears to structure perception and to have direct links to emotional states. METHODS:To investigate the automatic processing of face valence a sequential priming task based on emotion...
journal_title:Cognitive neuropsychiatry
pub_type: 杂志文章
doi:10.1080/13546800344000318
更新日期:2005-01-01 00:00:00
abstract:INTRODUCTION:Cognitive neuropsychiatry has had much success in providing theoretical models for the causal origins of many delusional beliefs. Recently, it has been suggested that some anorexia nervosa patients' beliefs about their own body size should be considered delusions. As such, it seems high time the methods of...
journal_title:Cognitive neuropsychiatry
pub_type: 杂志文章
doi:10.1080/13546805.2017.1401531
更新日期:2017-11-01 00:00:00
abstract:INTRODUCTION:Visual scanning is widely reported to be abnormal in schizophrenia. The majority of eye movement studies in schizophrenic patients have used pictures of a face in isolation in free viewings. This study was designed to examine whether attentional control, through instructions, modulates the visuomotor behav...
journal_title:Cognitive neuropsychiatry
pub_type: 杂志文章
doi:10.1080/13546805.2012.683245
更新日期:2013-05-01 00:00:00
abstract:INTRODUCTION:Studies comparing IQ in Offspring of Bipolar Parents (OBP) with Offspring of Healthy Controls (OHC) have reported conflicting findings. They have included OBP with mental health/neurodevelopmental disorders and/or pharmacological treatment which could affect results. This UK study aimed to assess IQ in OBP...
journal_title:Cognitive neuropsychiatry
pub_type: 杂志文章
doi:10.1080/13546805.2016.1259103
更新日期:2017-01-01 00:00:00
abstract::We describe a case of transient functional retrograde amnesia that had features of a fugue state, and that was accompanied by loss of personal identity and significant autobiographical amnesia. Uniquely, we were able to gather information from witnesses who observed the episode from its onset, and we were also able to...
journal_title:Cognitive neuropsychiatry
pub_type: 杂志文章
doi:10.1080/135468096396541
更新日期:1996-08-01 00:00:00
abstract::Introduction: Auditory verbal hallucinations (AVH) are a core symptom of psychotic disorders such as schizophrenia but are also reported in 10-15% of the general population. Impairments in self-voice recognition are frequently reported in schizophrenia and associated with the severity of AVH, particularly when the sel...
journal_title:Cognitive neuropsychiatry
pub_type: 杂志文章
doi:10.1080/13546805.2019.1621159
更新日期:2019-07-01 00:00:00
abstract:INTRODUCTION:In this paper, we argue for a novel account of one cognitive factor implicated in delusional cognition. According to the erotetic theory of delusion we present, the central cognitive factor in delusion is impaired endogenous question raising. METHOD:After presenting the erotetic theory, we draw on it to m...
journal_title:Cognitive neuropsychiatry
pub_type: 杂志文章
doi:10.1080/13546805.2015.1067601
更新日期:2015-01-01 00:00:00
abstract:INTRODUCTION:The failure of integrative brain function is a fundamental characteristic of schizophrenia. Synchronous Gamma (40 Hz) activity, proposed as a candidate mechanism underlying the integration ("binding") of distributed brain activities, may provide a direct window into schizophrenic disintegration. METHODS:4...
journal_title:Cognitive neuropsychiatry
pub_type: 杂志文章
doi:10.1080/713752240
更新日期:2003-02-01 00:00:00
abstract:INTRODUCTION:Previous research has suggested that biases in cognitive processes involved in everyday reasoning may contribute to the development of delusional beliefs. The aim of this study was to explore jumping to conclusions (JTC), a data-gathering bias, and jumping to perceptions (JTP), a bias towards believing amb...
journal_title:Cognitive neuropsychiatry
pub_type: 杂志文章
doi:10.1080/13546800903495684
更新日期:2010-07-01 00:00:00
abstract::Introduction: Cognitive impairment is related to an increase in cardiovascular risk (CVR) in the general population. However, in severe mental disorder (SMD), the evidence is less consistent. Few studies have evaluated the relationship between cognition and vascular burden in SMD. This study determines the relationshi...
journal_title:Cognitive neuropsychiatry
pub_type: 杂志文章
doi:10.1080/13546805.2019.1676709
更新日期:2020-01-01 00:00:00
abstract:INTRODUCTION:Although social cognition skills and biases are well-studied in paranoia, "mind perception" - perceiving the extent to which someone even possesses a thinking, feeling mind - is not. We sought to better characterise the profile of mind perception for individuals with paranoia. METHODS:We examined links be...
journal_title:Cognitive neuropsychiatry
pub_type: 杂志文章
doi:10.1080/13546805.2017.1287692
更新日期:2017-03-01 00:00:00
abstract::In order to ask whether autism is associated with difficulty in self-monitoring we gave a group of children and adolescents with autism a task in which they themselves had to remember whether they or another person had performed certain actions. In our first experiment, three groups of participants had to recall wheth...
journal_title:Cognitive neuropsychiatry
pub_type: 杂志文章
doi:10.1080/135468099395855
更新日期:1999-11-01 00:00:00
abstract::Patients with Gilles de la Tourette syndrome (TS) frequently show obsessions and compulsions. Pathophysiologically, TS has been linked to abnormalities of the basal ganglia and forebrain which are related to emotional processes. Because recordings of event-related potentials (ERPs) have shown that the emotional conten...
journal_title:Cognitive neuropsychiatry
pub_type: 杂志文章
doi:10.1080/135468099396052
更新日期:1999-02-01 00:00:00
abstract::Background: Jumping to conclusions (JTC) and overconfidence in errors are well established in individuals with a liability to psychosis. Experimental research suggests that subjecting individuals to dilemmas and doubt prompts a subsequent hardening of attitudes and may foster delusion-like convictions. For the present...
journal_title:Cognitive neuropsychiatry
pub_type: 杂志文章,随机对照试验
doi:10.1080/13546805.2019.1642863
更新日期:2019-07-01 00:00:00
abstract::Bipolar disorder is characterised by affective instability and mood dysregulation. Understanding of the neural mechanism underlying this remains limited, however. Here, findings will be described from studies that have employed neuroimaging techniques to measure neural responses to emotionally salient stimuli in indiv...
journal_title:Cognitive neuropsychiatry
pub_type: 杂志文章,评审
doi:10.1080/13546800444000290
更新日期:2006-05-01 00:00:00
abstract::Numerous genes modulate dopamine and consequently prefrontal cortical function. Some of these genes - notably catechol-O-methyltransferase - have been shown to impact a variety of core cognitive processes that are dependent upon the prefrontal cortex. This demonstration that a single functional polymorphism can contri...
journal_title:Cognitive neuropsychiatry
pub_type:
doi:10.1080/13546800903126016
更新日期:2009-01-01 00:00:00
abstract::Confabulations and delusions both involve the production of false claims. Although they may have different types of content, they share several characteristics. For example, they are often held with considerable conviction and are resistant to counter evidence, they may be acted upon, and they may be accompanied by a ...
journal_title:Cognitive neuropsychiatry
pub_type: 杂志文章,评审
doi:10.1080/13546800903441902
更新日期:2010-01-01 00:00:00
abstract:INTRODUCTION:Theories of delusions which rely on a combination of abnormal experience and defective belief evaluation and/ or cognitive bias are the subject of an emerging consensus. This paper challenges the validity of these theories and constructs a two factor alternative. METHODS:The paper starts by identifying th...
journal_title:Cognitive neuropsychiatry
pub_type: 杂志文章
doi:10.1080/13546805.2013.803959
更新日期:2014-01-01 00:00:00
abstract:INTRODUCTION:Recent reports of lexical-semantic deficits in patients with schizophrenia (Laws, Al-Uzri, & Mortimer, 2000; Laws, McKenna, & Kondel, 1998) suggest that younger patients have problems accessing intact memories and older patients show apparent "loss" of the lexical-semantic memory representations themselves...
journal_title:Cognitive neuropsychiatry
pub_type: 临床试验,杂志文章
doi:10.1080/13546800444000137
更新日期:2006-01-01 00:00:00
abstract::We used a variant of the Stroop paradigm to investigate attention bias in a young woman (JK) with delusional beliefs that she had died and that members of her family had changed. JK was shown sets of words printed in different colours of ink, and was asked to name the colour of each word. Sets of words were chosen whi...
journal_title:Cognitive neuropsychiatry
pub_type: 杂志文章
doi:10.1080/135468096396668
更新日期:1996-02-01 00:00:00