Abstract:
:Introduction: Cognitive impairment is related to an increase in cardiovascular risk (CVR) in the general population. However, in severe mental disorder (SMD), the evidence is less consistent. Few studies have evaluated the relationship between cognition and vascular burden in SMD. This study determines the relationship between cognition and vascular burden in patients with SMD.Methods: Sixty SMD patients (61% men, mean age: 46) attending a psychosocial rehabilitation centre were included. We evaluated sociodemographic, clinical, laboratory, quality of life and functionality characteristics. And we analysed the association between cognitive performance and vascular burden.Results: SMD diagnoses were: 41.7% schizophrenia, 20.0% bipolar, 5.0% schizoaffective, 21.7% depressive and 11.7% other. Cognitive impairment was present in 55% of the cases. The average vascular burden was 3.2. Patients with cognitive impairment have a significantly higher vascular burden than patients without cognitive impairment (p < 0.05). The speed of processing had a moderate correlation with vascular burden (r = -0.457, p = 0.001).Conclusions: Patients with cognitive impairment had a significantly higher vascular burden than patients without cognitive impairment. There are two practical clinical implications: CVR should be evaluated in all SMD patients; and psychoeducation programmes for CVR should be performed and adapted to the cognitive deficits.
journal_name
Cogn Neuropsychiatryjournal_title
Cognitive neuropsychiatryauthors
Foguet-Boreu Q,Guàrdia Sancho A,Santos Lopez JM,Roura Poch P,Palmarola Ginesta J,Puig-Ribera AM,Muñoz Pradós Jdoi
10.1080/13546805.2019.1676709subject
Has Abstractpub_date
2020-01-01 00:00:00pages
1-13issue
1eissn
1354-6805issn
1464-0619journal_volume
25pub_type
杂志文章abstract:INTRODUCTION:Recent reports of lexical-semantic deficits in patients with schizophrenia (Laws, Al-Uzri, & Mortimer, 2000; Laws, McKenna, & Kondel, 1998) suggest that younger patients have problems accessing intact memories and older patients show apparent "loss" of the lexical-semantic memory representations themselves...
journal_title:Cognitive neuropsychiatry
pub_type: 临床试验,杂志文章
doi:10.1080/13546800444000137
更新日期:2006-01-01 00:00:00
abstract:INTRODUCTION:Previous research suggests that latent inhibition is reduced in patients with acute schizophrenia and in healthy participants with high levels of schizotypic characteristics. Other evidence indicates the disruption of a related effect (learned irrelevance) in patients with acute schizophrenia. METHOD:This...
journal_title:Cognitive neuropsychiatry
pub_type: 杂志文章
doi:10.1080/13546800802664539
更新日期:2009-01-01 00:00:00
abstract::Introduction: Cognitive impairments are common in both Autism Spectrum Disorders (ASD) and schizophrenia, but it is unclear whether the pattern of difficulties is similar or different in the two disorders. This cross-sectional and longitudinal study compared the neuropsychological functioning in adolescents with ASD w...
journal_title:Cognitive neuropsychiatry
pub_type: 杂志文章
doi:10.1080/13546805.2020.1713736
更新日期:2020-05-01 00:00:00
abstract:INTRODUCTION:Previous research has suggested that biases in cognitive processes involved in everyday reasoning may contribute to the development of delusional beliefs. The aim of this study was to explore jumping to conclusions (JTC), a data-gathering bias, and jumping to perceptions (JTP), a bias towards believing amb...
journal_title:Cognitive neuropsychiatry
pub_type: 杂志文章
doi:10.1080/13546800903495684
更新日期:2010-07-01 00:00:00
abstract:INTRODUCTION:There is substantial evidence that patients with schizophrenia present with impaired Theory of Mind (ToM). Whereas previous studies have focused on general ToM abilities, the present study is aimed at testing the underlying behavioural and neurocognitive mechanisms of the impaired integration of affective ...
journal_title:Cognitive neuropsychiatry
pub_type: 杂志文章
doi:10.1080/13546800802490034
更新日期:2008-11-01 00:00:00
abstract::Introduction: Auditory verbal hallucinations (AVH) are a core symptom of psychotic disorders such as schizophrenia but are also reported in 10-15% of the general population. Impairments in self-voice recognition are frequently reported in schizophrenia and associated with the severity of AVH, particularly when the sel...
journal_title:Cognitive neuropsychiatry
pub_type: 杂志文章
doi:10.1080/13546805.2019.1621159
更新日期:2019-07-01 00:00:00
abstract::Numerous studies have suggested, via the interpretation of the negative priming effect as a measure of cognitive inhibition, that schizotypal subjects are less able to inhibit irrelevant distracting information. Recent research has revealed, however, that negative priming effects can be caused by two quite different p...
journal_title:Cognitive neuropsychiatry
pub_type: 杂志文章
doi:10.1080/135468097396423
更新日期:1997-02-01 00:00:00
abstract:INTRODUCTION:Theory-of-mind (ToM) refers to the ability to understand and predict the behaviour of others based on their mental states. Research from brain imaging and lesion studies indicate that the frontal lobes are both involved and necessary to understand mental states. METHODS:A total of 13 people with Parkinson...
journal_title:Cognitive neuropsychiatry
pub_type: 杂志文章
doi:10.1080/13546800244000292
更新日期:2003-08-01 00:00:00
abstract:INTRODUCTION:Visual scanning is widely reported to be abnormal in schizophrenia. The majority of eye movement studies in schizophrenic patients have used pictures of a face in isolation in free viewings. This study was designed to examine whether attentional control, through instructions, modulates the visuomotor behav...
journal_title:Cognitive neuropsychiatry
pub_type: 杂志文章
doi:10.1080/13546805.2012.683245
更新日期:2013-05-01 00:00:00
abstract:INTRODUCTION:The aim of the present study was to compare spatial working memory performance of females and males schizophrenia patients to verify whether the sexual dimorphism of spatial abilities present in the general population is found also in schizophrenia. METHODS:We analysed different types of errors committed ...
journal_title:Cognitive neuropsychiatry
pub_type: 杂志文章
doi:10.1080/13546800903399183
更新日期:2010-07-01 00:00:00
abstract:INTRODUCTION:A sample of everyday difficulties was collected, encompassing errors and unusual experiences participants had encountered when recognising their own faces in everyday life, with the aim of characterising similarities and differences between the reported difficulties and the major forms of self-recognition ...
journal_title:Cognitive neuropsychiatry
pub_type: 杂志文章
doi:10.1080/13546800344000075
更新日期:2004-08-01 00:00:00
abstract::In order to ask whether autism is associated with difficulty in self-monitoring we gave a group of children and adolescents with autism a task in which they themselves had to remember whether they or another person had performed certain actions. In our first experiment, three groups of participants had to recall wheth...
journal_title:Cognitive neuropsychiatry
pub_type: 杂志文章
doi:10.1080/135468099395855
更新日期:1999-11-01 00:00:00
abstract:INTRODUCTION:Most evidence suggests that schizophrenia is associated with pervasive prospective memory (PM) impairment that does not vary as a function of task demands. However, a central tenet of the Multiprocess Framework is that PM involves both automatic and strategic processes, and that their relative prominence v...
journal_title:Cognitive neuropsychiatry
pub_type: 杂志文章
doi:10.1080/13546805.2011.581536
更新日期:2012-01-01 00:00:00
abstract::The psychopathological basis of delusions in schizophrenia is poorly understood. The most enduring of several early theories has suggested a causal link with formal thought disorder, whereas recent approaches have proposed relationships with a variety of cognitive abnormalities. The correlations of delusions with othe...
journal_title:Cognitive neuropsychiatry
pub_type: 杂志文章
doi:10.1080/135468096396451
更新日期:1996-11-01 00:00:00
abstract:INTRODUCTION:It has been suggested that the positive symptoms of acute schizophrenia are a consequence of a disruption of the process that produces latent inhibition (slower acquisition of conditioned responding after preexposure to the conditioned stimulus) and that this effect can be modelled by pro- and antipsychoti...
journal_title:Cognitive neuropsychiatry
pub_type: 杂志文章,评审
doi:10.1080/13546805.2012.667202
更新日期:2012-11-01 00:00:00
abstract:INTRODUCTION:Category fluency is associated with speed-, executive- and semantic impairments in schizphrenia. It has traditionally been linked to negative symptoms, whereas the relation to positive symptoms is mixed. Associations to the consensus negative, positive and disorganisation factors have not been analysed bef...
journal_title:Cognitive neuropsychiatry
pub_type: 杂志文章,随机对照试验
doi:10.1080/13546805.2017.1418306
更新日期:2018-01-01 00:00:00
abstract::Introduction: Predictive coding models propose that high hypnotic suggestibility confers a predisposition to hallucinate due to an elevated propensity to weight perceptual beliefs (priors) over sensory evidence. Multiple lines of research corroborate this prediction and demonstrate a link between hypnotic suggestibili...
journal_title:Cognitive neuropsychiatry
pub_type: 杂志文章
doi:10.1080/13546805.2020.1715932
更新日期:2020-05-01 00:00:00
abstract:INTRODUCTION:In this paper, we argue for a novel account of one cognitive factor implicated in delusional cognition. According to the erotetic theory of delusion we present, the central cognitive factor in delusion is impaired endogenous question raising. METHOD:After presenting the erotetic theory, we draw on it to m...
journal_title:Cognitive neuropsychiatry
pub_type: 杂志文章
doi:10.1080/13546805.2015.1067601
更新日期:2015-01-01 00:00:00
abstract:INTRODUCTION:Research on empathy has a long tradition in clinical research, as deficits in empathy have been found in many mental disorders. Over decades, a large amount of measures for empathy have been developed, but in many cases these have not been analysed with respect to validity. Therefore, this paper aims to re...
journal_title:Cognitive neuropsychiatry
pub_type: 杂志文章
doi:10.1080/13546805.2014.991781
更新日期:2015-01-01 00:00:00
abstract::INTRODUCTION. This study used Item-Response Theory (IRT) to model the psychometric properties of a false belief picture sequencing task. Consistent with the mental time travel hypothesis of paranoia, we anticipated that performance on this deductive theory of mind (ToM) task would not be associated with the presence o...
journal_title:Cognitive neuropsychiatry
pub_type: 杂志文章
doi:10.1080/13546805.2011.574418
更新日期:2011-11-01 00:00:00
abstract:INTRODUCTION:We report a novel delusion, primarily persecutory in form, in which the patient believes that he is being filmed, and that the films are being broadcast for the entertainment of others. METHODS:We describe a series of patients who presented with a delusional system according to which they were the subject...
journal_title:Cognitive neuropsychiatry
pub_type: 杂志文章
doi:10.1080/13546805.2012.666113
更新日期:2012-11-01 00:00:00
abstract:BACKGROUND:Cohen et al.'s (1990, 1999) concept of context has been employed to explain various schizophrenic cognitive deficits. Braver et al.'s (2001) modified definition allows us to link context to cognitive complexity and explain a range of our experimental findings. METHOD:Saccadic and manual responses to experim...
journal_title:Cognitive neuropsychiatry
pub_type: 杂志文章
doi:10.1080/13546800802058658
更新日期:2008-05-01 00:00:00
abstract::Cognitive Neuropsychiatry has secured recognition in Thomson's Science and Social Science Citation Indices which will lead to the calculation of the journal impact factor. ...
journal_title:Cognitive neuropsychiatry
pub_type: 社论
doi:10.1080/13546805.2012.715800
更新日期:2012-01-01 00:00:00
abstract:INTRODUCTION:Cognitive impairment is a pervasive feature of schizophrenia, and is a major determinant of the functional disability that is characteristic of the disorder. However, research investigating whether patients with schizophrenia show a deficit awareness remains unclear. The present study aimed to replicate an...
journal_title:Cognitive neuropsychiatry
pub_type: 杂志文章
doi:10.1080/13546805.2014.909311
更新日期:2014-01-01 00:00:00
abstract:INTRODUCTION:Studies comparing IQ in Offspring of Bipolar Parents (OBP) with Offspring of Healthy Controls (OHC) have reported conflicting findings. They have included OBP with mental health/neurodevelopmental disorders and/or pharmacological treatment which could affect results. This UK study aimed to assess IQ in OBP...
journal_title:Cognitive neuropsychiatry
pub_type: 杂志文章
doi:10.1080/13546805.2016.1259103
更新日期:2017-01-01 00:00:00
abstract:INTRODUCTION:There is evidence that schizophrenics have an abnormal corpus callosum and an abnormal pattern of cerebral asymmetries. We investigated whether there are corresponding functional abnormalities in interhemispheric transfer (IT) and laterality effects. METHODS:Medicated schizophrenic patients and matched co...
journal_title:Cognitive neuropsychiatry
pub_type: 杂志文章
doi:10.1080/13546800143000195
更新日期:2002-05-01 00:00:00
abstract:BACKGROUND:Substance abuse is highly prevalent in schizophrenia and it has been associated with negative consequences on the course of the pathology. Regarding cognition, the prevailing literature has produced mixed results. Some groups have reported greater cognitive impairments in dual diagnosis schizophrenia, while ...
journal_title:Cognitive neuropsychiatry
pub_type: 杂志文章
doi:10.1080/13546800802264330
更新日期:2008-07-01 00:00:00
abstract:INTRODUCTION:Although important to cognitive neuropsychiatry and theories of delusions, Capgras delusion has largely been reported in single case studies. Bell et al. [2017. Uncovering Capgras delusion using a large scale medical records database. British Journal of Psychiatry Open, 3(4), 179-185] previously deployed c...
journal_title:Cognitive neuropsychiatry
pub_type: 杂志文章
doi:10.1080/13546805.2019.1584098
更新日期:2019-03-01 00:00:00
abstract:INTRODUCTION:Functional Cognitive Disorder (FCD) is poorly understood. We sought to better characterise FCD in order to inform future diagnostic criteria and evidence based treatments. Additionally, we compared FCD patients with and without co-morbid depression, including their neuropsychological profiles, to determine...
journal_title:Cognitive neuropsychiatry
pub_type: 杂志文章
doi:10.1080/13546805.2019.1590190
更新日期:2019-03-01 00:00:00
abstract:INTRODUCTION:Individuals with schizophrenia consistently show impairments in social cognition (SC). SC has become a potential treatment target due to its association with functional outcomes. An alternative method of assessment is to administer an observer-based scale incorporating an informant's "first hand" impressio...
journal_title:Cognitive neuropsychiatry
pub_type: 杂志文章
doi:10.1080/13546805.2014.999915
更新日期:2015-01-01 00:00:00