Association between cognitive impairment and cardiovascular burden in patients with severe mental disorder.

Abstract:

:Introduction: Cognitive impairment is related to an increase in cardiovascular risk (CVR) in the general population. However, in severe mental disorder (SMD), the evidence is less consistent. Few studies have evaluated the relationship between cognition and vascular burden in SMD. This study determines the relationship between cognition and vascular burden in patients with SMD.Methods: Sixty SMD patients (61% men, mean age: 46) attending a psychosocial rehabilitation centre were included. We evaluated sociodemographic, clinical, laboratory, quality of life and functionality characteristics. And we analysed the association between cognitive performance and vascular burden.Results: SMD diagnoses were: 41.7% schizophrenia, 20.0% bipolar, 5.0% schizoaffective, 21.7% depressive and 11.7% other. Cognitive impairment was present in 55% of the cases. The average vascular burden was 3.2. Patients with cognitive impairment have a significantly higher vascular burden than patients without cognitive impairment (p < 0.05). The speed of processing had a moderate correlation with vascular burden (r = -0.457, p = 0.001).Conclusions: Patients with cognitive impairment had a significantly higher vascular burden than patients without cognitive impairment. There are two practical clinical implications: CVR should be evaluated in all SMD patients; and psychoeducation programmes for CVR should be performed and adapted to the cognitive deficits.

journal_name

Cogn Neuropsychiatry

authors

Foguet-Boreu Q,Guàrdia Sancho A,Santos Lopez JM,Roura Poch P,Palmarola Ginesta J,Puig-Ribera AM,Muñoz Pradós J

doi

10.1080/13546805.2019.1676709

subject

Has Abstract

pub_date

2020-01-01 00:00:00

pages

1-13

issue

1

eissn

1354-6805

issn

1464-0619

journal_volume

25

pub_type

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